floxuridine has been researched along with Recrudescence in 7 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated 17 colorectal cancer patients' PyNPase and DPD activities in tumor and normal tissues using an enzyme-linked immunosorbent assay (ELISA) to assess their clinical significance as indicators for selecting colorectal cancer patients for 5'-DFUR together with MMC as adjuvant chemotherapy." | 6.73 | Pyrimidine nucleoside phosphorylase and dihydropyrimidine dihydrogenase activities as predictive factors for the efficacy of doxifluridine together with mitomycin C as adjuvant chemotherapy in primary colorectal cancer. ( Higashijima, J; Kurita, N; Miyamoto, H; Miyatani, T; Nishioka, M; Shimada, M; Yoshikawa, K, 2007) |
| "We investigated 17 colorectal cancer patients' PyNPase and DPD activities in tumor and normal tissues using an enzyme-linked immunosorbent assay (ELISA) to assess their clinical significance as indicators for selecting colorectal cancer patients for 5'-DFUR together with MMC as adjuvant chemotherapy." | 2.73 | Pyrimidine nucleoside phosphorylase and dihydropyrimidine dihydrogenase activities as predictive factors for the efficacy of doxifluridine together with mitomycin C as adjuvant chemotherapy in primary colorectal cancer. ( Higashijima, J; Kurita, N; Miyamoto, H; Miyatani, T; Nishioka, M; Shimada, M; Yoshikawa, K, 2007) |
| "Doxifluridine (5'-DFUR) is an intermediate of capecitabine approved in Europe and USA to treat metastatic colorectal cancer." | 2.71 | A randomized controlled trial of postoperative adjuvant immunochemotherapy for colorectal cancer with oral medicines. ( Koda, K; Kodaira, S; Miyazaki, M; Nakazato, H; Ogawa, K; Saito, N; Sarashina, H; Suwa, T; Suzuki, M; Watanabe, S, 2003) |
| "We enrolled 1217 primary breast cancer patients and randomly assigned them into two treatment groups; one received six-month postoperative 5'-DFUR treatment by consecutive or intermittent administration, and the other surgery alone." | 2.70 | The effect of adjuvant 5'-deoxy-5-fluorouridine in early stage breast cancer patients: results from a multicenter randomized controlled trial. ( Abe, O; Abe, R; Asaishi, K; Enomoto, K; Hattori, T; Hayasaka, H; Hirata, K; Izuo, M; Kimijima, I; Koyama, H; Miura, S; Monden, Y; Morimoto, T; Nakazato, H; Nomura, Y; Ohashi, Y; Ota, J; Senoo, T; Sonoo, H; Sugimachi, K; Taguchi, T; Toge, T; Toi, M; Tominaga, T; Uchino, J; Watanabe, H; Yamaguchi, S; Yoshida, M, 2002) |
| "He had type 3 gastric cancer on the posterior wall of vestibular part." | 1.38 | [A case report of complete response by weekly paclitaxel and 5'-DFUR combination chemotherapy for recurrenced gastric cancer with peritoneal dissemination]. ( Kondo, J; Nagashima, Y; Nakamura, M; Nishimura, T; Okada, T; Sakata, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kusama, M | 1 |
| Nakamura, M | 1 |
| Sakata, K | 1 |
| Kondo, J | 1 |
| Nishimura, T | 1 |
| Nagashima, Y | 1 |
| Okada, T | 1 |
| Koda, K | 1 |
| Miyazaki, M | 1 |
| Sarashina, H | 1 |
| Suwa, T | 1 |
| Saito, N | 1 |
| Suzuki, M | 1 |
| Ogawa, K | 1 |
| Watanabe, S | 1 |
| Kodaira, S | 1 |
| Nakazato, H | 2 |
| Nishioka, M | 1 |
| Miyamoto, H | 1 |
| Kurita, N | 1 |
| Higashijima, J | 1 |
| Yoshikawa, K | 1 |
| Miyatani, T | 1 |
| Shimada, M | 1 |
| Wong, MK | 1 |
| Bjarnason, GA | 1 |
| Hrushesky, WJ | 1 |
| Webster, P | 1 |
| Morava-Protzner, I | 1 |
| Towers, M | 1 |
| Tominaga, T | 1 |
| Toi, M | 1 |
| Abe, O | 1 |
| Ohashi, Y | 1 |
| Uchino, J | 1 |
| Hayasaka, H | 1 |
| Abe, R | 1 |
| Izuo, M | 1 |
| Enomoto, K | 1 |
| Watanabe, H | 1 |
| Yoshida, M | 1 |
| Taguchi, T | 1 |
| Koyama, H | 1 |
| Senoo, T | 1 |
| Toge, T | 1 |
| Monden, Y | 1 |
| Hattori, T | 1 |
| Nomura, Y | 1 |
| Sugimachi, K | 1 |
| Hirata, K | 1 |
| Miura, S | 1 |
| Morimoto, T | 1 |
| Asaishi, K | 1 |
| Kimijima, I | 1 |
| Ota, J | 1 |
| Sonoo, H | 1 |
| Yamaguchi, S | 1 |
| Serlin, O | 1 |
| Keehn, RJ | 1 |
| Higgins, GA | 1 |
| Harrower, HW | 1 |
| Mendeloff, GL | 1 |
4 trials available for floxuridine and Recrudescence
| Article | Year |
|---|---|
A randomized controlled trial of postoperative adjuvant immunochemotherapy for colorectal cancer with oral medicines.
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Colorect | 2003 |
Pyrimidine nucleoside phosphorylase and dihydropyrimidine dihydrogenase activities as predictive factors for the efficacy of doxifluridine together with mitomycin C as adjuvant chemotherapy in primary colorectal cancer.
Topics: Adult; Aged; Antineoplastic Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Dihydrouracil D | 2007 |
The effect of adjuvant 5'-deoxy-5-fluorouridine in early stage breast cancer patients: results from a multicenter randomized controlled trial.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Disease-Free Survival; Female; Floxu | 2002 |
Factors related to survival following resection for gastric carcinoma: analysis of 903 cases.
Topics: Adult; Aged; Clinical Trials as Topic; Floxuridine; Humans; Male; Middle Aged; Prognosis; Recurrence | 1977 |
3 other studies available for floxuridine and Recrudescence
| Article | Year |
|---|---|
[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide(DMpC)combination therapy found effective for case of chest wall recurrent breast cancer with bone and pleural metastases].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophospha | 2012 |
[A case report of complete response by weekly paclitaxel and 5'-DFUR combination chemotherapy for recurrenced gastric cancer with peritoneal dissemination].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Floxuridine; Gastre | 2012 |
Steroid-responsive interstitial lung disease in patients receiving 2'-deoxy-5-fluorouridine-infusion chemotherapy. A report of three cases.
Topics: Aged; Carcinoma, Renal Cell; Cough; Dyspnea; Female; Fever; Floxuridine; Forced Expiratory Volume; H | 1995 |