Page last updated: 2024-11-06

floxuridine and Pregnancy

floxuridine has been researched along with Pregnancy in 63 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"The most commonly used multiagent chemotherapy for high-risk gestational trophoblastic neoplasia (GTN) is etoposide, methotrexate and actinomycin D/cyclophosphamide and vincristine (EMA/CO) worldwide."8.02Results with Floxuridine, Actinomycin D, Etoposide, and Vincristine in Gestational Trophoblastic Neoplasias with International Federation of Gynecology and Obstetrics Scores ≥5. ( Feng, F; Kong, Y; Li, Y; Ren, T; Wan, X; Xiang, Y; Yang, J; Zhao, J, 2021)
"To analyze the reproductive outcomes of gestational trophoblastic neoplasia (GTN) patients who were cured only by floxuridine-based regimens."7.96Reproductive outcomes after floxuridine-based regimens for gestational trophoblastic neoplasia: A retrospective cohort study in a national referral center in China. ( Feng, FZ; Jiang, F; Ren, T; Wan, XR; Xiang, Y; Yang, JJ; Yang, K; Zhao, J, 2020)
"To evaluate the efficacy and toxicity profile of floxuridine, dactinomycin, etoposide and vincristine (FAEV) regimen as primary treatment in stage IV gestational trophoblastic neoplasia (GTN)."7.83Primary treatment of stage IV gestational trophoblastic neoplasia with floxuridine, dactinomycin, etoposide and vincristine (FAEV): A report based on our 10-year clinical experiences. ( Feng, F; Ren, T; Wan, X; Xiang, Y; Yang, J, 2016)
"To evaluate the combination chemotherapy regimen with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) as primary treatment for gestational trophoblastic neoplasia (GTN)."7.80Combination chemotherapy regimen with floxuridine, dactinomycin, etoposide, and vincristine as primary treatment for gestational trophoblastic neoplasia. ( Feng, FZ; Ren, T; Wan, XR; Wang, T; Xiang, Y, 2014)
"Guidelines recommend etoposide, methotrexate, actinomycin D (EMA)/cyclophosphamide, vincristine (CO) as first-line treatment for high-risk gestational trophoblastic neoplasia (GTN)."5.51Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia. ( Feng, F; Ji, M; Jiang, S; Ren, T; Wan, X; Xiang, Y; Yang, J; Zhao, J, 2022)
"Although most patients with gestational trophoblastic neoplasia (GTN) are cured by conventional chemotherapy, some develop drug resistance or relapse."5.37Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia. ( Feng, F; Geng, S; Wan, X; Wang, T; Xiang, Y, 2011)
"The most commonly used multiagent chemotherapy for high-risk gestational trophoblastic neoplasia (GTN) is etoposide, methotrexate and actinomycin D/cyclophosphamide and vincristine (EMA/CO) worldwide."4.02Results with Floxuridine, Actinomycin D, Etoposide, and Vincristine in Gestational Trophoblastic Neoplasias with International Federation of Gynecology and Obstetrics Scores ≥5. ( Feng, F; Kong, Y; Li, Y; Ren, T; Wan, X; Xiang, Y; Yang, J; Zhao, J, 2021)
"To analyze the reproductive outcomes of gestational trophoblastic neoplasia (GTN) patients who were cured only by floxuridine-based regimens."3.96Reproductive outcomes after floxuridine-based regimens for gestational trophoblastic neoplasia: A retrospective cohort study in a national referral center in China. ( Feng, FZ; Jiang, F; Ren, T; Wan, XR; Xiang, Y; Yang, JJ; Yang, K; Zhao, J, 2020)
"To evaluate the efficacy and toxicity profile of floxuridine, dactinomycin, etoposide and vincristine (FAEV) regimen as primary treatment in stage IV gestational trophoblastic neoplasia (GTN)."3.83Primary treatment of stage IV gestational trophoblastic neoplasia with floxuridine, dactinomycin, etoposide and vincristine (FAEV): A report based on our 10-year clinical experiences. ( Feng, F; Ren, T; Wan, X; Xiang, Y; Yang, J, 2016)
"To evaluate the combination chemotherapy regimen with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) as primary treatment for gestational trophoblastic neoplasia (GTN)."3.80Combination chemotherapy regimen with floxuridine, dactinomycin, etoposide, and vincristine as primary treatment for gestational trophoblastic neoplasia. ( Feng, FZ; Ren, T; Wan, XR; Wang, T; Xiang, Y, 2014)
"Treatment of choriocarcinoma cells (JAr line) for 24 hr with methotrexate, fluorodeoxyuridine, 1-beta-D-arabinofuranosylcytosine, or hydroxyurea, in doses that inhibit DNA synthesis, results in a 2."3.66Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis. ( Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K, 1979)
"Whether gastric cancer in young adults differs from gastric cancer in older patients has been a controversial issue."2.41Gastric cancer in very young adults: apropos four patients and a review of the literature. ( Fiehler, J; Höffken, K; Kath, R; Schneider, CP, 2000)
"Chemotherapy is typically used to treat choriocarcinoma."1.46CLIC1 Induces Drug Resistance in Human Choriocarcinoma Through Positive Regulation of MRP1. ( Wang, D; Wu, J, 2017)
"Although most patients with gestational trophoblastic neoplasia (GTN) are cured by conventional chemotherapy, some develop drug resistance or relapse."1.37Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia. ( Feng, F; Geng, S; Wan, X; Wang, T; Xiang, Y, 2011)
" Dose-response relationships of skeleton variations and malformations induced by three antineoplastic drugs (FUDR: 5-fluoro-2'-deoxyuridine, HU: hydroxyurea and 6-MPr: 6-mercaptopurine-riboside) were evaluated."1.35Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment. ( Chahoud, I; Paumgartten, FJ, 2009)
"Spinal canal metastasis secondary to gestational trophoblastic neoplasia (GTN) is a rare condition."1.35Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report. ( Cao, Y; Feng, F; Xiang, Y, 2009)
"Cleft palate was induced in rat foetuses using 5-fluoro-2-desoxyuridine and was associated with greatly decreased mucopolysaccharide synthesis."1.26Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate. ( Ferguson, MW, 1981)

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-199037 (58.73)18.7374
1990's7 (11.11)18.2507
2000's8 (12.70)29.6817
2010's8 (12.70)24.3611
2020's3 (4.76)2.80

Authors

AuthorsStudies
Ji, M1
Jiang, S1
Zhao, J5
Wan, X8
Feng, F7
Ren, T7
Yang, J5
Xiang, Y13
Jiang, F2
Yang, K1
Wan, XR4
Feng, FZ2
Yang, JJ1
Li, Y1
Kong, Y2
Li, J3
Wang, X1
Liu, R1
Lin, G1
Xu, H1
Wang, T2
Xiao, C1
Chahoud, I2
Talsness, CE1
Walter, A1
Grote, K1
Wu, J1
Wang, D1
Paumgartten, FJ1
Cao, Y1
Geng, S1
Yang, XY2
Wu, Y4
Yang, YM1
Yin, SJ1
GENTRY, GA2
LAWSON, LA1
RANDALL, CC2
KARNOFSKY, DA1
BASCH, RS1
Yang, X2
Yang, Y1
Ying, S1
Liu, N2
Chen, L2
Dong, RF1
Doherty, GH1
Dong, R1
Hecht, F1
Jacky, PB1
Sutherland, GR2
Brookwell, R1
Daniel, A1
Turner, G1
Fishburn, J1
Ritter, EJ3
Scott, WJ2
Wilson, JG2
Lampkin, BC1
Neely, JE1
Whatley, SA1
Hall, C1
Lim, L1
Ferguson, MW1
Knudsen, TB1
Kochhar, DM1
Mathinos, PR1
Randall, JL1
Jenkins, EC2
Morys, I1
Henderson, J1
Genovese, M1
Carter, M1
Li, SY1
Houck, GE1
Ding, X1
Stark-Houck, SL1
Dobkin, CS1
Yokoyama, M1
Morrison, RS1
Black, IB1
Dreyfus, CF1
Amwayi, PJ1
Otiang'a-Owiti, GE1
Hou, JG1
Cohen, G1
Mytilineou, C2
Nagao, T1
Kuwagata, M1
Saito, Y1
Kath, R1
Fiehler, J1
Schneider, CP1
Höffken, K1
Forsthoefel, PF1
Williams, ML1
Langman, J3
Cardell, EL1
Azizkhan, JC1
Speeg, KV1
Stromberg, K1
Goode, D1
Krawczun, MS1
Brooks, SE1
Brooks, SL1
Sherman, SL1
Brown, WT1
Casper, D1
Blum, M1
Galloway, WD1
Brown, NT1
Khan, KM1
Baker, E1
Purvis-Smith, S1
Hockey, A1
Krumins, E1
Eichenbaum, SZ1
Gibas, LM1
Grujic, S1
Barr, MA1
Jackson, LG1
von Koskull, H1
Aula, P1
Ammälä, P1
Nordström, AM1
Rapola, J1
Ishiwata, K1
Ido, T1
Kawashima, K1
Yamada, H1
Takahashi, T1
Iwata, R1
Matsui, A1
Sakuragawa, N1
Bro-Rasmussen, F3
Jensen, B3
Sorensen, AH2
Brent, RL1
Bolden, BT1
Weiss, A1
Manning, JP1
Carter, SG1
Calenti, L1
Anderson, JI1
Hansen, OM1
Ostergaard, AH1
Ruch, JV1
Karcher-Djuricic, V1
Omori, K1
Nicol, AG1
Conkie, D1
Lanyon, WG1
Drewienkiewicz, CE1
Williamson, R1
Paul, J1
Williams, JP1
Owens, IS1
Vonderhaar, BK3
Topper, YJ3
Webster, W1
Shimada, M1
Andreoli, J1
Rodier, P1
Flickinger, RA1
Bradley, MO1
Kleinbrecht, J1
O'Callaghan, DJ1
Hyde, JM1

Reviews

3 reviews available for floxuridine and Pregnancy

ArticleYear
The fragile X chromosome: current methods.
    American journal of medical genetics, 1982, Volume: 11, Issue:4

    Topics: Cells, Cultured; Chromosome Fragility; Chromosome Mapping; Female; Fibroblasts; Floxuridine; Folic A

1982
Gastric cancer in very young adults: apropos four patients and a review of the literature.
    Journal of cancer research and clinical oncology, 2000, Volume: 126, Issue:4

    Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Cis

2000
The role of gene redundancy and number of cell divisions in embryonic determination.
    The ... Symposium. Society for Developmental Biology. Symposium, 1970, Volume: 29

    Topics: Amphibians; Animals; Anura; Cell Differentiation; Cell Division; Collagen; DNA Replication; Embryoni

1970

Trials

3 trials available for floxuridine and Pregnancy

ArticleYear
Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia.
    British journal of cancer, 2022, Volume: 127, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Floxuridine; Gestat

2022
Floxuridine-containing regimens in the treatment of gestational trophoblastic tumor.
    The Journal of reproductive medicine, 2004, Volume: 49, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Fe

2004
Efficacy of the FAEV regimen in the treatment of high-risk, drug-resistant gestational trophoblastic tumor.
    The Journal of reproductive medicine, 2007, Volume: 52, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin; Dactinomycin; Drug Re

2007

Other Studies

57 other studies available for floxuridine and Pregnancy

ArticleYear
Reproductive outcomes after floxuridine-based regimens for gestational trophoblastic neoplasia: A retrospective cohort study in a national referral center in China.
    Gynecologic oncology, 2020, Volume: 159, Issue:2

    Topics: Adult; Antimetabolites, Antineoplastic; China; Female; Fertility Preservation; Floxuridine; Gestatio

2020
Results with Floxuridine, Actinomycin D, Etoposide, and Vincristine in Gestational Trophoblastic Neoplasias with International Federation of Gynecology and Obstetrics Scores ≥5.
    The oncologist, 2021, Volume: 26, Issue:12

    Topics: Dactinomycin; Etoposide; Female; Floxuridine; Gestational Trophoblastic Disease; Humans; Obstetrics;

2021
Clinical characteristics and prognosis of ultra high-risk gestational trophoblastic neoplasia patients: A retrospective cohort study.
    Gynecologic oncology, 2017, Volume: 146, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Dactinomycin; Eto

2017
An efficient method for dorsal root ganglia neurons purification with a one-time anti-mitotic reagent treatment.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Female; Floxuridine; Ganglia, Spinal; Immunohistochemistry;

2013
Combination chemotherapy regimen with floxuridine, dactinomycin, etoposide, and vincristine as primary treatment for gestational trophoblastic neoplasia.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2014, Volume: 36, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Floxuridine;

2014
Management and prognosis of patients with brain metastasis from gestational trophoblastic neoplasia: a 24-year experience in Peking union medical college hospital.
    BMC cancer, 2015, Apr-28, Volume: 15

    Topics: Adult; Brain Neoplasms; China; Combined Modality Therapy; Dactinomycin; Disease-Free Survival; Drug

2015
Postnatal investigation of prenatally induced effects on the vertebral column of rats reduces the uncertainty of classification of anomalies.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 58

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Female; Floxuridine; Gestational Age; Male; Pregn

2015
Primary treatment of stage IV gestational trophoblastic neoplasia with floxuridine, dactinomycin, etoposide and vincristine (FAEV): A report based on our 10-year clinical experiences.
    Gynecologic oncology, 2016, Volume: 143, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Floxuridine;

2016
CLIC1 Induces Drug Resistance in Human Choriocarcinoma Through Positive Regulation of MRP1.
    Oncology research, 2017, Jul-05, Volume: 25, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chloride Channels; Choriocarcinoma; Drug

2017
Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment.
    Environmental research, 2009, Volume: 109, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone and Bones; Dose-Response Relationship, Drug; Female; Floxuridin

2009
Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.
    The Journal of reproductive medicine, 2009, Volume: 54, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta

2009
Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dactinomycin; Dru

2011
[Floxuridine-containing regime in the treatment of gestational trophoblastic tumor].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2003, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols;

2003
REPLICATION OF A DEOXYRIBONUCLEIC ACID VIRUS IN THYMINE-DEFICIENT MAMMALIAN CELLS.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Animals; DNA; DNA Replication; DNA, Viral; Female; Floxuridine; Horses; Methotrexate; Nucleotides; P

1964
Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.
    The Journal of biophysical and biochemical cytology, 1960, Volume: 7

    Topics: Cytidine; DNA; Female; Floxuridine; Fluorouracil; Humans; Orotic Acid; Pregnancy; Pyrimidines; Thymi

1960
[Efficacy of FAEV regimen in treatment of high-risk drug-resistant gestational trophoblastic tumor].
    Zhonghua fu chan ke za zhi, 2006, Volume: 41, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chorionic Gonadotropin, beta Subunit, Human;

2006
Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons.
    Neuroscience research, 2007, Volume: 57, Issue:2

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cytochromes c; Dopamine; Dose-Re

2007
The fragile X(q27) form of X-linked mental retardation: FUdR as an inducing agent for fra(X)(q27) expression in lymphocytes, fibroblasts, and amniocytes.
    American journal of medical genetics, 1982, Volume: 13, Issue:2

    Topics: Cells, Cultured; Female; Floxuridine; Fragile X Syndrome; Humans; Lymphocytes; Male; Pedigree; Pheno

1982
Potentiation of teratogenesis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:3 Pt 1

    Topics: Animals; Antibiotics, Antineoplastic; Cytarabine; DNA; Drug Synergism; Embryo, Mammalian; Female; Fl

1984
Effect of 5-fluoro-2'-deoxyuridine on deoxyribonucleotide pools in vivo.
    Journal of the National Cancer Institute, 1980, Volume: 65, Issue:3

    Topics: Animals; Culture Techniques; Deoxyribonucleotides; Embryo, Mammalian; Female; Floxuridine; Humans; M

1980
Hypothalamic neurons in dissociated cell culture: the mechanism of increased survival times in the presence of non-neuronal cells.
    Journal of neurochemistry, 1981, Volume: 36, Issue:6

    Topics: Animals; Cell Communication; Cell Division; Cell Survival; Cells, Cultured; Female; Floxuridine; Hyp

1981
Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate.
    British journal of orthodontics, 1981, Volume: 8, Issue:3

    Topics: Alligators and Crocodiles; Animals; Cleft Palate; Disease Models, Animal; Female; Floxuridine; Micro

1981
Limb development in mouse embryos. III. Cellular events underlying the determination of altered skeletal patterns following treatment with 5'fluoro-2-deoxyuridine.
    Teratology, 1981, Volume: 23, Issue:2

    Topics: Animals; Bone and Bones; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Extremities

1981
Potentiative interactions between caffeine and various teratogenic agents.
    Teratology, 1982, Volume: 25, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Res

1982
Fragile X induction systems in CVS cultures: effect on cytogenetic, PCR, and genomic Southern Blot DNA analyses of the FMR-1 gene.
    American journal of medical genetics, 1994, Jul-15, Volume: 51, Issue:4

    Topics: Blotting, Southern; Cells, Cultured; Chorionic Villi; Chorionic Villi Sampling; Chromosome Banding;

1994
Septal neuron cholinergic and GABAergic functions: differential regulation by basic fibroblast growth factor and epidermal growth factor.
    Brain research. Developmental brain research, 1994, Apr-15, Volume: 78, Issue:2

    Topics: Acetylcholine; Animals; Brain; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Embryo,

1994
Use of biometric embryonic growth parameters as indicator of exposure to a teratogen.
    East African medical journal, 1997, Volume: 74, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Anthropometry; Embryonic and Fetal Development; Female; Floxur

1997
Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system.
    Journal of neurochemistry, 1997, Volume: 69, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Female; Fetus; Fibroblast Growth Factor 2

1997
Effects of prenatal exposure to 5-fluoro-2'-deoxyuridine on developing central nervous system and reproductive function in male offspring of mice.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites, Antineoplastic; Brain; DNA Fragmentation; Dos

1998
The effects of 5-fluorouracil and 5-fluorodeoxyuridine used alone and in combination with normal nucleic acid precursors on development of mice in lines selected for low and high expression of Strong's luxoid gene.
    Teratology, 1975, Volume: 11, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cell Survival; Drug Synergism; Female; Fetal Deat

1975
Cell degeneration and recovery of the fetal mammalian brain after a chemical insult.
    Teratology, 1977, Volume: 16, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Cell Movement; Cell Survival; DNA Replication; Female;

1977
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-R

1979
Laboratory aspects of prenatal fra(X) detection.
    Progress in clinical and biological research, 1991, Volume: 368

    Topics: Amniocentesis; Cells, Cultured; Chorionic Villi Sampling; Dose-Response Relationship, Drug; False Ne

1991
EGF enhances the survival of dopamine neurons in rat embryonic mesencephalon primary cell culture.
    Journal of neuroscience research, 1991, Volume: 30, Issue:2

    Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Dopamine; Epidermal Growth Factor; ErbB Rece

1991
Mouse pup vocalizations following in utero exposure to fluorodeoxyuridine.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Female; Floxuridine; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Vocalization, Anim

1986
Protective role of compensatory growth in the development of mammalian inner ear.
    JPMA. The Journal of the Pakistan Medical Association, 1986, Volume: 36, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Ear, Inner; Female; Floxuridine; Pregnancy; Rats; Rats, Inbred

1986
Prenatal diagnosis of the fragile X using thymidine induction.
    Prenatal diagnosis, 1987, Volume: 7, Issue:3

    Topics: Adult; Amniocentesis; Australia; Chorionic Villi; Female; Floxuridine; Fragile X Syndrome; Humans; M

1987
A simple technique for obtaining high quality chromosome preparations from chorionic villus samples using FdU synchronization.
    Prenatal diagnosis, 1987, Volume: 7, Issue:5

    Topics: Chorionic Villi; Chromosome Banding; Chromosomes, Human; Female; Floxuridine; Genetic Techniques; Hu

1987
Improved technique for the expression of fragile-X in cultured amniotic fluid cells.
    Human genetics, 1985, Volume: 69, Issue:3

    Topics: Adult; Amniotic Fluid; Cells, Cultured; Chromosome Fragility; Diazepam; Female; Floxuridine; Humans;

1985
Placental transfer of positron-emitting radionuclides in metabolic substrates.
    International journal of nuclear medicine and biology, 1985, Volume: 12, Issue:1

    Topics: Adenine; Amino Acids; Animals; Carbohydrate Metabolism; Carbon Isotopes; Electrons; Female; Fetus; F

1985
"Spontaneous" amputations.
    Lancet (London, England), 1972, Apr-22, Volume: 1, Issue:7756

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amputation, Surgical; Animals; Female; Floxuridi

1972
The use of uterine vascular clamping in the pregnant rat to modify the embryotoxic effects of anticancer drugs.
    Cancer research, 1968, Volume: 28, Issue:10

    Topics: Aminopterin; Animals; Chemotherapy, Cancer, Regional Perfusion; Female; Fetus; Floxuridine; Fluorour

1968
Transformation of precursor protein to an active enzyme molecule in the decidual alkaline phosphatase respone of the pseudopregnant rat; studies with nucleic acid inhibitors and amino acid antagonists.
    Enzymologia, 1969, Volume: 36, Issue:4

    Topics: Alkaline Phosphatase; Amino Acids; Animals; Chloramphenicol; Cycloheximide; Dactinomycin; Decidua; E

1969
Fluorodeoxyuridine-induced malformations in mice. Studies on the early stages of teratogenesis.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cleft Palate; Clubfoot; Encephalocele; Femal

1971
[Preliminary results of the in vitro action of 5-fluoro-deoxyuridine on the differentiation of the odontoblasts].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Volume: 164, Issue:11

    Topics: Animals; Cell Differentiation; Cells, Cultured; Female; Floxuridine; In Vitro Techniques; Mice; Odon

1970
Teratogenic effects of 5-fluoro-2'-deoxyuridine in pregnant mice.
    Teratology, 1972, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Floxuridine; Liver; Mice; Nucleic A

1972
Characteristics of erythropoietin-induced RNA from foetal mouse liver erythropoietic cell cultures and the effects of 5-fluorodeoxyuridine.
    Biochimica et biophysica acta, 1972, Aug-25, Volume: 277, Issue:2

    Topics: Animals; Autoradiography; Cells, Cultured; Chemical Phenomena; Chemistry; DNA; Electrophoresis, Poly

1972
Congenital meromelia or "spontaneous amputations". Experimental studies on mice.
    Acta orthopaedica Scandinavica, 1972, Volume: 43, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Animals, Newborn; Ectromelia; Female;

1972
Incorporation of thymidine after administration of fluorouracil and fluorouridine to adult and embryo mice.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, Drug; E

1971
Concerning the necessary coupling of development to proliferation of mouse mammary epithelial cells.
    The Journal of biological chemistry, 1973, Jan-25, Volume: 248, Issue:2

    Topics: Animals; Caseins; Culture Techniques; Cytarabine; Deoxyribonucleosides; DNA; Enzyme Induction; Epith

1973
Effect of fluorodeoxyuridine, colcemid, and bromodeoxyuridine on developing neocortex of the mouse.
    The American journal of anatomy, 1973, Volume: 137, Issue:1

    Topics: Animals; Benzocycloheptenes; Bromodeoxyuridine; Cell Differentiation; Cell Movement; Cell Nucleus; C

1973
The influence of a prenatal trauma on formation of Purkinje cells.
    The American journal of anatomy, 1973, Volume: 137, Issue:1

    Topics: Animals; Cerebellum; Female; Fetal Diseases; Floxuridine; Gestational Age; Mice; Mitosis; Pregnancy;

1973
Critical cell proliferation as a prerequisite for differentiation of mammary epithelial cells.
    Enzyme, 1973, Volume: 15, Issue:1

    Topics: Animals; Caseins; Cell Differentiation; Cytarabine; Epithelium; Estradiol; Female; Floxuridine; Gluc

1973
Arginase activity patterns and their regulation during embryonic development in liver and kidney.
    Developmental biology, 1973, Volume: 33, Issue:1

    Topics: Animals; Arginase; Cycloheximide; Cytidine; Dactinomycin; DNA; Enzyme Activation; Female; Floxuridin

1973
A role of the cell cycle in hormone-dependent differentiation.
    The Journal of cell biology, 1974, Volume: 63, Issue:2 Pt 1

    Topics: Animals; Carbon Radioisotopes; Cell Division; Cells, Cultured; Cytarabine; DNA; Epithelium; Female;

1974
The embryotoxic effects of 5-fluoro-2'-deoxyuridine in mice.
    Teratology, 1970, Volume: 3, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetus; Floxuridine;

1970
Kinetics of viral deoxyribonucleic acid, protein, and infectious particle production and alterations in host macromolecular syntheses in equine abortion (herpes) virus-infected cells.
    Journal of virology, 1968, Volume: 2, Issue:8

    Topics: Abortion, Veterinary; Animals; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytopathogenic Ef

1968