floxuridine has been researched along with Necrosis in 18 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We have studied the mechanisms regulating cell death (necrosis in original F28-7 cells and apoptosis in their variant F28-7-A cells) in the mouse mammary tumor cell line FM3A using the anticancer agent floxuridine (FUdR)." | 3.96 | Intracellular microRNA expression patterns influence cell death fates for both necrosis and apoptosis. ( Funayama, N; Hiramoto, A; Kim, HS; Ogino, Y; Sato, A; Shimotsuma, A; Takahashi, Y; Wataya, Y; Yamamoto, A, 2020) |
| "The first was treated for synovial sarcoma of a metatarsal." | 1.30 | Soft-tissue complications of intra-arterial chemotherapy for extremity sarcomas. ( Bezwada, HP; Granick, MS; Lackman, RL; Long, CD; Moore, JH; Weiss, AJ, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, A | 9 |
| Yamamoto, A | 2 |
| Shimotsuma, A | 1 |
| Ogino, Y | 1 |
| Funayama, N | 1 |
| Takahashi, Y | 1 |
| Hiramoto, A | 9 |
| Wataya, Y | 11 |
| Kim, HS | 10 |
| Nakama, K | 3 |
| Watanabe, H | 1 |
| Satake, A | 8 |
| Omi, T | 1 |
| Masutani, M | 1 |
| Miyazaki, E | 5 |
| Naito, T | 2 |
| Uchikubo, Y | 2 |
| Hiraoka, O | 4 |
| Miyake, T | 4 |
| Okamatsu, A | 2 |
| Hasegawa, T | 1 |
| Mitani, S | 1 |
| Kemeny, MM | 1 |
| Alava, G | 1 |
| Oliver, JM | 1 |
| Bezwada, HP | 1 |
| Granick, MS | 1 |
| Long, CD | 1 |
| Moore, JH | 1 |
| Lackman, RL | 1 |
| Weiss, AJ | 1 |
| Kakutani, T | 1 |
| Ebara, Y | 1 |
| Kanja, K | 1 |
| Hidaka, M | 1 |
| Matsumoto, Y | 1 |
| Nagano, A | 1 |
| Shibata, T | 1 |
| Sasaki, Y | 1 |
| Imaoka, S | 1 |
| Wada, H | 1 |
| Nagano, H | 1 |
| Ishikawa, O | 1 |
| Ohigashi, H | 1 |
| Fukuda, I | 1 |
| Kabuto, T | 1 |
| Hiratsuka, M | 1 |
| Komuro, K | 1 |
| Mitsumori, N | 1 |
| Iwamoto, K | 1 |
| Murai, R | 1 |
| Ishida, T | 1 |
| Nagasaki, Y | 1 |
| Hujii, Y | 1 |
| Amano, R | 1 |
| Yamazaki, M | 1 |
| Nagayama, A | 1 |
| Kocks, I | 1 |
| Körber, W | 1 |
| Larena-Avellaneda, A | 1 |
| Reed, WP | 1 |
| Newman, KA | 1 |
| Applefeld, MM | 1 |
| Sutton, FJ | 1 |
| Bro-Rasmussen, F | 1 |
| Jensen, B | 1 |
| Sorensen, AH | 1 |
18 other studies available for floxuridine and Necrosis
| Article | Year |
|---|---|
Intracellular microRNA expression patterns influence cell death fates for both necrosis and apoptosis.
Topics: Animals; Apoptosis; Benzoquinones; Cell Line, Tumor; Down-Regulation; Floxuridine; Gene Expression P | 2020 |
Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine.
Topics: Activating Transcription Factor 3; Animals; Apoptosis; Cell Line, Tumor; Floxuridine; HSP90 Heat-Sho | 2014 |
Association of nuclear membrane protein lamin B1 with necrosis and apoptosis in cell death induced by 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Cell Death; Cell Line, Tumor; Floxuridine; | 2008 |
Gene expression profiles of necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cytochromes c; Floxuridine; G | 2008 |
Molecular mechanisms in two cell death-types, necrosis and apoptosis, induced by 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Floxuridine; Lamin Type B; Mi | 2008 |
Association of nuclear-intermediate filament lamin B1 with necrotic- and apoptotic-morphologies in cell death induced by 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Floxuridine; Lamin Type B; Mi | 2009 |
Protein expression profiles of necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine in mouse cancer cells.
Topics: Amino Acid Sequence; Animals; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Size; Electrophor | 2010 |
Mechanisms of cell death induced by 5-fluoro-2'-deoxyuridine (FUdR)--necrosis or apoptosis after treated with FUdR.
Topics: Apoptosis; Floxuridine; Genes, fos; Genes, jun; Genes, myc; Necrosis; RNA, Messenger | 2002 |
Proteome and transcriptome analysis of 5-fluoro-2'-deoxyuridine-induced cell death mechanisms.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Floxuridine; Gene Expression | 2006 |
Proteome and transcriptome analysis of cell death induced by 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Floxuridine; Gene Expression | 2007 |
The effects on liver metastases of circadian patterned continuous hepatic artery infusion of FUDR.
Topics: Adenocarcinoma; Animals; Catheterization, Peripheral; Circadian Rhythm; Drug Administration Schedule | 1994 |
Soft-tissue complications of intra-arterial chemotherapy for extremity sarcomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chondrosarcoma; Cisplatin; Doxorubicin; Extre | 1998 |
Different modes of cell death induced by 5-fluoro-2'-deoxyuridine in two clones of the mouse mammary tumor FM3A cell line.
Topics: Animals; Apoptosis; Caspase 1; Caspase 3; Caspases; Clone Cells; Cysteine Endopeptidases; DNA Fragme | 1998 |
[Selective anticancer effects of intra-arterial infusion of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine (TT82) in hepatocellular carcinoma].
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Combined Modality Therapy; Drug Ev | 1989 |
[A case of remission of metastatic gastric cancer lesions in the chest and abdominal wall by 5'-DFUR administration].
Topics: Abdominal Muscles; Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Female; Floxuridine; | 1985 |
[Bronchobiliary fistula in necrotizing liver metastasis of sigmoid cancer following regional chemotherapy].
Topics: Biliary Fistula; Bronchial Fistula; Female; Floxuridine; Humans; Infusions, Intra-Arterial; Liver; L | 1988 |
Drug extravasation as a complication of venous access ports.
Topics: Adolescent; Adult; Aged; Dobutamine; Extravasation of Diagnostic and Therapeutic Materials; Floxurid | 1985 |
Congenital meromelia or "spontaneous amputations". Experimental studies on mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Animals, Newborn; Ectromelia; Female; | 1972 |