Page last updated: 2024-11-06

floxuridine and Meningeal Neoplasms

floxuridine has been researched along with Meningeal Neoplasms in 8 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.

Research Excerpts

ExcerptRelevanceReference
"In metastatic brain tumors from lung, breast, and gastric cancer, the average time from the diagnosis of primary cancer to brain metastasis was shorter in cases with high activities and longer in cases with low activities."1.27[Activities of pyrimidine nucleoside phosphorylase in brain tumors and antitumor effect of 5'-DFUR]. ( Miki, Y; Miwa, M; Nomura, K; Shibui, S; Watanabe, T, 1983)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakagawa, H6
Miyahara, E2
Suzuki, T1
Wada, K1
Tamura, M2
Fukushima, Y2
Yoshioka, K1
Itoh, K1
Shibui, S1
Watanabe, T1
Miki, Y1
Nomura, K1
Miwa, M1
Yamada, M4
Fukushima, M2
Shimizu, K1
Ikenaka, K4
Maeda, N2
Iwatsuki, K2
Tsuzuki, T1
Hirayama, A2
Yamamoto, H1
Kobayashi, T1

Trials

3 trials available for floxuridine and Meningeal Neoplasms

ArticleYear
Continuous intrathecal administration of 5-fluoro-2'-deoxyuridine for the treatment of neoplastic meningitis.
    Neurosurgery, 2005, Volume: 57, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Child; Drug Administration Schedule;

2005
[Clinical application of FdUrd to meningeal dissemination of malignant tumors].
    No shinkei geka. Neurological surgery, 1998, Volume: 26, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Drug Admin

1998
Clinical trial of intrathecal administration of 5-fluoro-2'-deoxyuridine for treatment of meningeal dissemination of malignant tumors.
    Journal of neuro-oncology, 1999, Volume: 45, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Floxuridine; Follow-Up Studies; Huma

1999

Other Studies

5 other studies available for floxuridine and Meningeal Neoplasms

ArticleYear
Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:8

    Topics: Actins; Agar; Amides; Animals; Brain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cells, Culture

2005
[Activities of pyrimidine nucleoside phosphorylase in brain tumors and antitumor effect of 5'-DFUR].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:10

    Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Floxuridine; Glioma; Humans; Meningeal Neoplasm

1983
[In vivo study on intrathecal use of 5-fluoro-2'-deoxyuridine (FdUrd) in meningeal dissemination of malignant tumor].
    No shinkei geka. Neurological surgery, 1998, Volume: 26, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Brain; Floxuridine; Injections, Spinal; Meningeal Neoplasm

1998
Intrathecal 5-fluoro-2'-deoxyuridine (FdUrd) for the treatment of solid tumor neoplastic meningitis: an in vivo study.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain; Female; Floxuridine; Humans; Injections, Spinal; Meningeal Ne

1999
[New developments in chemotherapy for experimental brain metastasis].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Flo

1985
chemdatabank.com