floxuridine and Meningeal Neoplasms
floxuridine has been researched along with Meningeal Neoplasms in 8 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"In metastatic brain tumors from lung, breast, and gastric cancer, the average time from the diagnosis of primary cancer to brain metastasis was shorter in cases with high activities and longer in cases with low activities." | 1.27 | [Activities of pyrimidine nucleoside phosphorylase in brain tumors and antitumor effect of 5'-DFUR]. ( Miki, Y; Miwa, M; Nomura, K; Shibui, S; Watanabe, T, 1983) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (25.00) | 18.7374 |
1990's | 4 (50.00) | 18.2507 |
2000's | 2 (25.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Nakagawa, H | 6 |
Miyahara, E | 2 |
Suzuki, T | 1 |
Wada, K | 1 |
Tamura, M | 2 |
Fukushima, Y | 2 |
Yoshioka, K | 1 |
Itoh, K | 1 |
Shibui, S | 1 |
Watanabe, T | 1 |
Miki, Y | 1 |
Nomura, K | 1 |
Miwa, M | 1 |
Yamada, M | 4 |
Fukushima, M | 2 |
Shimizu, K | 1 |
Ikenaka, K | 4 |
Maeda, N | 2 |
Iwatsuki, K | 2 |
Tsuzuki, T | 1 |
Hirayama, A | 2 |
Yamamoto, H | 1 |
Kobayashi, T | 1 |
Trials
3 trials available for floxuridine and Meningeal Neoplasms
Article | Year |
---|---|
Continuous intrathecal administration of 5-fluoro-2'-deoxyuridine for the treatment of neoplastic meningitis.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Child; Drug Administration Schedule; | 2005 |
[Clinical application of FdUrd to meningeal dissemination of malignant tumors].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Drug Admin | 1998 |
Clinical trial of intrathecal administration of 5-fluoro-2'-deoxyuridine for treatment of meningeal dissemination of malignant tumors.
Topics: Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Floxuridine; Follow-Up Studies; Huma | 1999 |
Other Studies
5 other studies available for floxuridine and Meningeal Neoplasms
Article | Year |
---|---|
Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
Topics: Actins; Agar; Amides; Animals; Brain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cells, Culture | 2005 |
[Activities of pyrimidine nucleoside phosphorylase in brain tumors and antitumor effect of 5'-DFUR].
Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Floxuridine; Glioma; Humans; Meningeal Neoplasm | 1983 |
[In vivo study on intrathecal use of 5-fluoro-2'-deoxyuridine (FdUrd) in meningeal dissemination of malignant tumor].
Topics: Animals; Antimetabolites, Antineoplastic; Brain; Floxuridine; Injections, Spinal; Meningeal Neoplasm | 1998 |
Intrathecal 5-fluoro-2'-deoxyuridine (FdUrd) for the treatment of solid tumor neoplastic meningitis: an in vivo study.
Topics: Animals; Antineoplastic Agents; Brain; Female; Floxuridine; Humans; Injections, Spinal; Meningeal Ne | 1999 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Flo | 1985 |