floxuridine has been researched along with Mast-Cell Sarcoma in 3 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Mast-Cell Sarcoma: A unifocal malignant tumor that consists of atypical pathological MAST CELLS without systemic involvement. It causes local destructive growth in organs other than in skin or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The increase in lifespan (ILS) of mice treated with 5'-DFUR was augmented by the combination with guanosine or inosine in a dose-dependent fashion, and the maximum ILS was about 160% with the combination, while that in the case of 5'-DFUR alone was only 48% in the P388 leukemia system." | 1.27 | Potentiation of the chemotherapeutic action of 5'-deoxy-5-fluorouridine in combination with guanosine and related compounds. ( Iigo, M; Ishitsuka, H; Miwa, M; Nitta, K, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, DB | 1 |
| Lingwood, CA | 1 |
| Iigo, M | 1 |
| Miwa, M | 1 |
| Ishitsuka, H | 1 |
| Nitta, K | 1 |
| Schindler, R | 1 |
| Ramseier, L | 1 |
| Kolb, B | 1 |
3 other studies available for floxuridine and Mast-Cell Sarcoma
| Article | Year |
|---|---|
A model of cell cycle control: effects of thymidine on synchronous cell cultures.
Topics: Animals; Cell Count; Cell Division; Cell Line; Centrifugation, Zonal; DNA, Neoplasm; Floxuridine; Ma | 1975 |
Potentiation of the chemotherapeutic action of 5'-deoxy-5-fluorouridine in combination with guanosine and related compounds.
Topics: Animals; Drug Synergism; Floxuridine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Inosi | 1987 |
[Mutation to inhibitor-resistance and backward mutation to inhibitor-sensitivity in cancer cell cultures].
Topics: Animals; Culture Media; Culture Techniques; Floxuridine; Glycine; Hypoxanthines; Mast-Cell Sarcoma; | 1967 |