Page last updated: 2024-11-06

floxuridine and Lymphoma

floxuridine has been researched along with Lymphoma in 12 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
"The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines."7.66Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980)
"The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines."3.66Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980)
"The object of this study was to develop a sustained release implantable dosage form of a new silicone gel (PHYCON 6600R) which undergoes addition polymerization to produce a solid gel at ordinary temperature."1.28Application of new silicone gel to sustained release dosage form of antitumor drug. ( Azuma, T; Imasaka, K; Kawaguchi, T; Nagai, T; Ueda, H, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MARUYAMA, Y1
SILINI, G1
KAPLAN, HS1
Saiko, P1
Horvath, Z1
Illmer, C1
Madlener, S1
Bauer, W1
Hoechtl, T1
Erlach, N1
Grusch, M1
Krupitza, G1
Mader, RM1
Jaeger, W1
Schott, H1
Agarwal, RP1
Fritzer-Szekeres, M1
Szekeres, T1
Hartmann, HR1
Matter, A1
Cohen, A1
Ullman, B2
Maybaum, J1
Mandel, HG1
Day, JL1
Sadee, W1
Nakagawa, H1
Yamada, M1
Maeda, N1
Iwatsuki, K1
Hirayama, A1
Ikenaka, K1
Riccardi, C1
Giampietri, A1
Puccetti, P1
Biancifiori, F1
Fioretti, MC1
Imasaka, K1
Ueda, H1
Azuma, T1
Kawaguchi, T1
Nagai, T1
Kanzawa, F1
Matsushima, Y1
Ishihara, J1
Hoshi, A1
Ohba, T1
Watanabe, K1
Painter, RB1
Young, BR1
Nesnow, S1
Mian, AM1
Oki, T1
Dexter, DL1
Heidelberger, C1
Lehmann, AR1
Kirk-Bell, S1
Shall, S1
Whish, WJ1

Trials

1 trial available for floxuridine and Lymphoma

ArticleYear
Clinical trial of intrathecal administration of 5-fluoro-2'-deoxyuridine for treatment of meningeal dissemination of malignant tumors.
    Journal of neuro-oncology, 1999, Volume: 45, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Floxuridine; Follow-Up Studies; Huma

1999

Other Studies

11 other studies available for floxuridine and Lymphoma

ArticleYear
STUDIES OF THE LSA ASCITES LYMPHOMA OF C57B1 MICE. II. RADIOSENSITIZATION IN VIVO WITH 5-BROMODEOXYCYTIDINE AND COMBINED 5-FLUORODEOXYURIDINE AND 5-BROMODEOXYCYTIDINE.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1963, Volume: 7

    Topics: Ascites; Bromodeoxycytidine; DNA; DNA, Neoplasm; Floxuridine; Lymphoma; Mice; Neoplasms; Neoplasms,

1963
Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.
    Leukemia research, 2005, Volume: 29, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Dimerization; Floxuridine; Human

2005
Antiproliferative action of a novel fluorinated uridine analog, 5'-deoxy-5-fluorouridine, measured in vitro and in vivo on four different murine tumor lines.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Animals; Cell Line; Drug Evaluation, Preclinical; Floxuridine; Isomerism; Lung Neoplasms; Lymphoma;

1982
Role of intracellular dTTP levels in fluorodeoxyuridine toxicity.
    Biochemical pharmacology, 1984, Oct-15, Volume: 33, Issue:20

    Topics: Animals; Cell Line; Floxuridine; Lymphoma; Mice; Mutation; Nucleosides; Thymidylate Synthase; Thymin

1984
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Animals; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Leu

1980
Murine leukemia growth inhibition or enhancement following immunization with tumor cells antigenically altered by drug treatment.
    Pharmacological research communications, 1977, Volume: 9, Issue:4

    Topics: Animals; Antigens, Neoplasm; Cells, Cultured; Dacarbazine; Female; Floxuridine; Gamma Rays; Idoxurid

1977
Application of new silicone gel to sustained release dosage form of antitumor drug.
    Drug design and delivery, 1989, Volume: 4, Issue:3

    Topics: Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Implants; Floxuridine; Gels; L

1989
Antitumor activity of alkylesters of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP) against murine lymphoma L5178Y resistant to 5-fluoro-2'-deoxyuridine.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Deoxyuracil Nucleotides; Drug Resistance;

1986
Repair replication in mammalian cells after x-irradiation.
    Mutation research, 1972, Volume: 14, Issue:2

    Topics: Animals; Base Sequence; Bromodeoxyuridine; Cell Line; Cells, Cultured; Centrifugation, Density Gradi

1972
Fluorinated pyrimidines. 41. Syntheses of 5-trifluoromethyl-3'-deoxyuridine and 5-fluoro-3'-deoxyuridine.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:6

    Topics: Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Ion Exc

1972
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.
    Experimental cell research, 1974, Volume: 83, Issue:1

    Topics: Adenosine Diphosphate; Animals; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin;

1974