Page last updated: 2024-11-06

floxuridine and Local Neoplasm Recurrence

floxuridine has been researched along with Local Neoplasm Recurrence in 85 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Research Excerpts

ExcerptRelevanceReference
"We conducted a phase II study to determine the availability and safety of combination chemotherapy with weekly paclitaxel and doxifluridine (a capecitabine metabolite) in the treatment of advanced or recurrent breast cancer."9.13Efficacy of doxifluridine combined with weekly paclitaxel therapy in the treatment of advanced or recurrent breast cancer: results of the JMTO BC01 phase II trial. ( Asaishi, K; Doi, T; Inaba, M; Kimura, M; Nishimura, R; Okamoto, Y; Okuyama, N; Takeuchi, H; Tamaki, N; Tominaga, T; Yanagita, Y, 2008)
"Twenty-four eligible patients (23 of whom were evaluated) with advanced and metastatic breast cancer were treated at the Saitama Cancer Center every 4 weeks with pirarubicin (30 mg/m2 i."9.09[Therapeutic efficacy of pirarubicin cyclophosphamide and doxifluridine in advanced and metastatic breast cancer]. ( Higashi, Y; Inoue, K; Kurosumi, M; Suemasu, K; Tabei, T, 1999)
"We investigated efficacy and tolerance of chemotherapy with doxifluridine (5'-DFUR) and docetaxel (TXT) in advanced/recurrent breast cancer."9.09[A phase I study of docetaxel (TXT) and doxifluridine (5'-DFUR) combination therapy in patients with advanced and recurrent breast cancer]. ( Aoyama, H; Asaga, T; Iwase, H; Kimura, M; Mitsuyama, S; Nishimura, R; Tominaga, T, 2001)
"To evaluate the feasibility and efficacy of weekly paclitaxel and 5'-DFUR combination therapy in advanced or recurrent breast cancer, 13 patients were enrolled in this pilot study."7.72[Evaluation of weekly paclitaxel and doxifluridine (5'-DFUR) combination therapy in patients with advanced or recurrent breast cancer]. ( Kou, Y; Okamoto, Y; Okuyama, N; Sawada, T; Tominaga, T, 2003)
"Two cases of recurrent breast cancer are reported in which chemotherapy with mitoxantrone proved remarkably effective."7.70[Chemotherapy with mitoxantrone for the treatment of recurrent breast cancer]. ( Katagata, N; Matsuoka, T; Nomizu, T; Takenoshita, S; Tsuchiya, A; Watanabe, F; Yabuta, T; Yamaki, Y, 2000)
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."7.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
"We treated fifteen patients with recurrent breast cancer by a combination of mitoxantrone (8 mg/m i."7.69[Efficacy of combination chemotherapy with mitoxantrone, vincristine, doxifluridine and prednisolone for recurrence of breast cancer]. ( Katsumata, K; Kawasaki, M; Koyanagi, Y; Kusama, M; Moriwaki, R; Murano, A; Nagakawa, Y; Ogata, T; Shibata, K; Yamamoto, K, 1997)
"A comparative study was performed to evaluate the efficacy and safety of 5'-DFUR and tegafur in recurrent breast cancer."7.67[A comparative study of 5'-DFUR and tegafur in recurrent breast cancer]. ( Abe, O; Ogawa, N; Taguchi, T; Terasawa, T; Tominaga, T; Yoshida, Y, 1985)
"A total of 112 patients with pTa or pT1 bladder cancer were eligible for the analysis and were allocated to either an adjuvant group (TURBT+5'-DFUR; n = 47; initial 23 months) or a control group (TURBT alone; n = 65, final 23 months)."6.71Novel prophylactic effect of doxifluridine in superficial bladder cancer. ( Aoki, A; Baba, Y; Jojima, K; Matsuyama, H; Naito, K; Shimabukuro, T; Suga, A; Suyama, K; Uchiyama, K; Yamamoto, N, 2004)
"In treating advanced or recurrent breast cancer, anthracycline-containing chemotherapy is used for palliation and to maintain quality of life."6.705'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer. ( Akao, S; Hiraide, H; Ishikawa, H; Maruyama, M; Matsumoto, F; Mochizuki, H; Okamura, H; Sato , K; Tabei, T; Tamakuma, S; Touma, M; Yagi, Y, 2001)
"A comparative study of 5'-DFUR 600 mg/day alone (C-arm) or in combination with TAM 30 mg/day (A-arm) or MPA 600 mg/day (B-arm) was carried out."6.38[A comparative study with 5'-DFUR alone or in combination with tamoxifen (TAM) or medroxyprogesterone acetate (MPA) for advanced or recurrent breast cancer]. ( Aikawa, T; Hirai, T; Kotsuma, Y; Maeura, Y; Miyauchi, K; Takatsuka, Y; Yayoi, E, 1992)
"Guidelines recommend etoposide, methotrexate, actinomycin D (EMA)/cyclophosphamide, vincristine (CO) as first-line treatment for high-risk gestational trophoblastic neoplasia (GTN)."5.51Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia. ( Feng, F; Ji, M; Jiang, S; Ren, T; Wan, X; Xiang, Y; Yang, J; Zhao, J, 2022)
"Although most patients with gestational trophoblastic neoplasia (GTN) are cured by conventional chemotherapy, some develop drug resistance or relapse."5.37Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia. ( Feng, F; Geng, S; Wan, X; Wang, T; Xiang, Y, 2011)
"We report a postmenopausal recurrent breast cancer patient with triple negative disease who presented with right recurrent nerve palsy."5.35[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide (DMpC) combination therapy is effective against recurrent triple negative breast cancer--a case report]. ( Jinta, E; Sakurai, T; Shimizu, S; Suzuma, T; Umemura, T; Yoshimura, G, 2008)
"For metastatic breast cancer patients who have hormone receptor-positive tumors, hormonal therapy aiming at optimal palliation and prolongation of life is the initial treatment of choice."5.32[Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer]. ( Fuchimoto, S; Inagaki, M; Miyoshi, K; Nakagawa, T; Ohsaki, T; Ohtsuka, S; Yumura, M, 2004)
"Concurrent carboplatin chemotherapy did not significantly improve the long-term survival after inductive carboplatin and floxuridine chemotherapy in locoregionally advanced nasopharyngeal carcinoma."5.20Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area. ( Cao, KJ; Guo, L; Guo, X; Hong, MH; Huang, PY; Mai, HQ; Mo, HY; Qian, CN; Wu, PH; Zeng, Q, 2015)
"We conducted a phase II study to determine the availability and safety of combination chemotherapy with weekly paclitaxel and doxifluridine (a capecitabine metabolite) in the treatment of advanced or recurrent breast cancer."5.13Efficacy of doxifluridine combined with weekly paclitaxel therapy in the treatment of advanced or recurrent breast cancer: results of the JMTO BC01 phase II trial. ( Asaishi, K; Doi, T; Inaba, M; Kimura, M; Nishimura, R; Okamoto, Y; Okuyama, N; Takeuchi, H; Tamaki, N; Tominaga, T; Yanagita, Y, 2008)
"We investigated efficacy and tolerance of chemotherapy with doxifluridine (5'-DFUR) and docetaxel (TXT) in advanced/recurrent breast cancer."5.09[A phase I study of docetaxel (TXT) and doxifluridine (5'-DFUR) combination therapy in patients with advanced and recurrent breast cancer]. ( Aoyama, H; Asaga, T; Iwase, H; Kimura, M; Mitsuyama, S; Nishimura, R; Tominaga, T, 2001)
"Twenty-four eligible patients (23 of whom were evaluated) with advanced and metastatic breast cancer were treated at the Saitama Cancer Center every 4 weeks with pirarubicin (30 mg/m2 i."5.09[Therapeutic efficacy of pirarubicin cyclophosphamide and doxifluridine in advanced and metastatic breast cancer]. ( Higashi, Y; Inoue, K; Kurosumi, M; Suemasu, K; Tabei, T, 1999)
"Fifty-nine patients with invasive primary gastric adenocarcinoma who were deemed resectable for cure entered a clinical trial that called for 2 cycles of protracted infusion 5-fluorouracil with weekly leucovorin and cisplatin chemotherapy followed by surgery."5.08Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report. ( Baranda, J; Casagrande, Y; Crookes, P; Groshen, S; Laine, L; Leichman, CG; Leichman, L; Silberman, H; Stain, S; Tan, M, 1997)
"High-dose toremifene therapy (120 mg/day) is useful for the recurrence of receptor-positive breast cancer."3.74[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy]. ( Murakami, S; Yamamoto, Y, 2007)
"To evaluate the feasibility and efficacy of weekly paclitaxel and 5'-DFUR combination therapy in advanced or recurrent breast cancer, 13 patients were enrolled in this pilot study."3.72[Evaluation of weekly paclitaxel and doxifluridine (5'-DFUR) combination therapy in patients with advanced or recurrent breast cancer]. ( Kou, Y; Okamoto, Y; Okuyama, N; Sawada, T; Tominaga, T, 2003)
"Two cases of recurrent breast cancer are reported in which chemotherapy with mitoxantrone proved remarkably effective."3.70[Chemotherapy with mitoxantrone for the treatment of recurrent breast cancer]. ( Katagata, N; Matsuoka, T; Nomizu, T; Takenoshita, S; Tsuchiya, A; Watanabe, F; Yabuta, T; Yamaki, Y, 2000)
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."3.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
"We treated fifteen patients with recurrent breast cancer by a combination of mitoxantrone (8 mg/m i."3.69[Efficacy of combination chemotherapy with mitoxantrone, vincristine, doxifluridine and prednisolone for recurrence of breast cancer]. ( Katsumata, K; Kawasaki, M; Koyanagi, Y; Kusama, M; Moriwaki, R; Murano, A; Nagakawa, Y; Ogata, T; Shibata, K; Yamamoto, K, 1997)
"A comparative study was performed to evaluate the efficacy and safety of 5'-DFUR and tegafur in recurrent breast cancer."3.67[A comparative study of 5'-DFUR and tegafur in recurrent breast cancer]. ( Abe, O; Ogawa, N; Taguchi, T; Terasawa, T; Tominaga, T; Yoshida, Y, 1985)
" No DLT was observed in level 2, and this combination therapy seemed safe and feasible for outpatients."2.72[Evaluation of safety and efficacy for bi-weekly Docetaxel and 5'-DFUR combination therapy in patients with advanced or recurrent breast cancer--Phase I study]. ( Ikeda, M; Ishiguro, K; Kataoka, T; Komaki, K; Kurebayashi, J; Morimoto, T; Sonoo, H; Tanaka, K; Tangoku, A; Yoshizawa, K, 2006)
"A total of 112 patients with pTa or pT1 bladder cancer were eligible for the analysis and were allocated to either an adjuvant group (TURBT+5'-DFUR; n = 47; initial 23 months) or a control group (TURBT alone; n = 65, final 23 months)."2.71Novel prophylactic effect of doxifluridine in superficial bladder cancer. ( Aoki, A; Baba, Y; Jojima, K; Matsuyama, H; Naito, K; Shimabukuro, T; Suga, A; Suyama, K; Uchiyama, K; Yamamoto, N, 2004)
" The mean dosage per course of TXT was 58."2.71[Bi-weekly chemotherapy with medium-dose docetaxel for advanced and recurrent breast cancers (The 15th study of Keiji Breast Cancer Study Group)]. ( Fujii, K; Fujino, S; Higashide, S; Hori, T; Inamoto, T; Kan, N; Lee, CJ; Maruhashi, K; Mise, K; Mitsumori, M; Nishimura, S; Okamoto, M; Okamura, T; Sawai, S; Takemoto, Y; Yamauchi, A, 2005)
" The purpose of the present study was to examine the efficacy of long-term administration of 5'-DFUR/CPA for patients with recurrent breast cancer."2.71The efficacy of long-term oral chemotherapy with 5'-deoxy-5-fluorouridine and cyclophosphamide for recurrent breast cancer. ( Aihara, N; Fukunaga, M; Iba, T; Kidokoro, A; Suda, M; Sugiyama, K, 2004)
"Most colorectal cancers metastatic to the liver are resistant to chemotherapy and are not amenable to surgical resection."2.70Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil. ( Bilchik, AJ; Chawla, SP; Chung, MH; Foshag, LJ; Ramming, KP; Rose, DM; Stern, SS; Wood, TF, 2001)
"In treating advanced or recurrent breast cancer, anthracycline-containing chemotherapy is used for palliation and to maintain quality of life."2.705'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer. ( Akao, S; Hiraide, H; Ishikawa, H; Maruyama, M; Matsumoto, F; Mochizuki, H; Okamura, H; Sato , K; Tabei, T; Tamakuma, S; Touma, M; Yagi, Y, 2001)
"Patients with one to three potentially resectable metastases were randomized preoperatively to receive no further therapy (control arm, 56 patients) or postoperative hepatic arterial floxuridine combined with intravenous continuous-infusion fluorouracil (chemotherapy arm, 53 patients)."2.70Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy--an intergroup study. ( Adak, S; Benson, AB; Gray, B; Kemeny, MM; Lipsitz, S; Macdonald, JS; O'Dwyer, PJ; Sigurdson, ER; Smith, T, 2002)
"However, in bladder cancer, response rates have only been reported in Phase II clinical trials."2.69[5'-DFUR chemoprophylaxis in superficial bladder cancer. Kanagawa Urology 5'-DFUR Study Group]. ( Chiba, K; Ebato, T; Fukuda, M; Fukuoka, H; Fukushima, S; Hirokawa, M; Hosaka, M; Ikeda, I; Kanno, H; Kitami, K; Kondo, I; Kubota, Y; Masuda, M; Miura, T; Miyai, K; Moriyama, M; Noguchi, K; Noguchi, S; Sasaki, K; Sato, K; Senga, Y, 2000)
"Leukocytopenia was more severe in group B."2.67[Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy] ( Ito, T; Komatsu, Y; Moriya, N; Ogasawara, H; Saito, S; Sakata, Y; Sugimoto, N; Tamura, Y; Tsushima, K; Yamada, Y, 1994)
" Fluorodeoxyuridine (FUDR) or 5-fluorouracil (5-FU) was used as the agent and a total dosage of 10-20 g was administered for 6-12 months in most studies."2.41[The role of prophylactic hepatic arterial infusion chemotherapy after potentially curative resection of hepatic metastases from colorectal cancer]. ( Monden, T; Tono, T, 2000)
"A comparative study of 5'-DFUR 600 mg/day alone (C-arm) or in combination with TAM 30 mg/day (A-arm) or MPA 600 mg/day (B-arm) was carried out."2.38[A comparative study with 5'-DFUR alone or in combination with tamoxifen (TAM) or medroxyprogesterone acetate (MPA) for advanced or recurrent breast cancer]. ( Aikawa, T; Hirai, T; Kotsuma, Y; Maeura, Y; Miyauchi, K; Takatsuka, Y; Yayoi, E, 1992)
"Sarcopenia was prevalent (48%) and was associated with a worse survival (HR 2."1.48Implementation and early outcomes for a surgeon-directed hepatic arterial infusion pump program for colorectal liver metastases. ( Abdel-Misih, S; Beal, EW; Bloomston, M; Chafitz, A; Chakedis, J; Davidson, G; Dillhoff, M; Galo, J; Pawlik, TM; Reardon, J; Schmidt, CR; Sun, S, 2018)
"Among 62 patients with ovarian cancer enrolled in IP platinum doublet studies in clinical trials (with etoposide (n = 18), with floxuridine (n = 30), and with topotecan (n = 14)), a deleterious BRCA mutation was eventually identified in 10 patients."1.40Ovarian cancer in BRCA mutation carriers: improved outcome after intraperitoneal (IP) cisplatin. ( Curtin, J; Downey, A; Edwards, S; Kwa, M; Muggia, F; Reich, E; Wallach, R, 2014)
"Although most patients with gestational trophoblastic neoplasia (GTN) are cured by conventional chemotherapy, some develop drug resistance or relapse."1.37Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia. ( Feng, F; Geng, S; Wan, X; Wang, T; Xiang, Y, 2011)
"We report a postmenopausal recurrent breast cancer patient with triple negative disease who presented with right recurrent nerve palsy."1.35[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide (DMpC) combination therapy is effective against recurrent triple negative breast cancer--a case report]. ( Jinta, E; Sakurai, T; Shimizu, S; Suzuma, T; Umemura, T; Yoshimura, G, 2008)
"Many patients with gastric cancer respond to TS-1, but some fail to respond or have recurrence."1.34Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1. ( Arai, W; Haruta, H; Hirashima, Y; Hosoya, Y; Hyodo, M; Kurashina, K; Nagai, H; Saito, S; Sakuma, K; Yasuda, Y; Yokoyama, T; Zuiki, T, 2007)
"We designed a new regimen to evaluate the efficacy and feasibility of weekly paclitaxel combined with orally administered 5'-DFUR therapy against advanced and recurrent gastric cancer."1.33[Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study]. ( Deguchi, Y; Kamimura, K; Kaneko, I; Kii, E; Murata, T; Tsubono, M; Yasumizu, R, 2005)
"The data on 307 patients with colorectal cancer at stage II or III, who underwent potentially curative resection with lymphadenectomy, were reviewed."1.33The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. ( Ikeda, S; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Ogo, S; Ohkita, A; Ozasa, H; Sasatomi, T; Shirouzu, K, 2006)
"For metastatic breast cancer patients who have hormone receptor-positive tumors, hormonal therapy aiming at optimal palliation and prolongation of life is the initial treatment of choice."1.32[Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer]. ( Fuchimoto, S; Inagaki, M; Miyoshi, K; Nakagawa, T; Ohsaki, T; Ohtsuka, S; Yumura, M, 2004)
"In the field of gastric cancer treatment, especially for patients showing multiple resistance to anticancer drugs, an effective therapy is critically needed."1.31Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens. ( Kurihara, M; Matsukawa, M; Nakamachi, M; Sato, A; Shimada, K; Ushio, J; Yamamoto, W, 2002)
"A 55-year-old woman with recurrent breast cancer treated with sequential mastectomies, chemo-and hormonal therapy of UFT, CPM and TAM, achieved remission."1.29[A case of recurrent breast cancer responding to long-term treatment with 5'-DFUR combined with MPA]. ( Kimura, M; Koida, T; Sekihara, M, 1996)
"The authors report a case with esophageal cancer who had undergone a non-curative resection and showed a recurrence."1.28[A case of recurrent esophageal cancer maintaining complete long-term response after 5'-DFUR and ftorafur administrations]. ( Fujimura, N; Ishida, C; Koyama, S; Maezato, K; Makino, N; Matsukawa, Y; Matsumoto, K; Mizuno, Y; Naitoh, M; Yamamoto, E, 1992)
" These dose-response data indicate that locally recurrent tumors are frequently, but not always, different from the original primary tumor in response to chemotherapy agents and ionizing X-irradiation."1.27Development and characterization of a rat model for locally recurring mammary tumors: sensitivities to 5-fluoro-2'-deoxyuridine, adriamycin, and X-irradiation. ( Aeed, PA; Estrada, J; Welch, DR, 1988)
"5'-DFUR was administered orally to recurrent breast cancer patients at a daily dosage of 1,200 mg given 3 times a day for more than 8 weeks."1.27[Clinical trial of 5'-DFUR in patients with recurrent breast cancer]. ( Komaki, K; Konishi, Y; Miki, H; Monden, Y; Morimoto, T; Ooshimo, K; Tanaka, T; Uomine, Y; Yamakawa, T, 1988)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-19908 (9.41)18.7374
1990's23 (27.06)18.2507
2000's38 (44.71)29.6817
2010's15 (17.65)24.3611
2020's1 (1.18)2.80

Authors

AuthorsStudies
Ji, M1
Jiang, S1
Zhao, J1
Wan, X2
Feng, F2
Ren, T1
Yang, J1
Xiang, Y2
Dhir, M1
Zenati, MS1
Jones, HL1
Bartlett, DL1
Choudry, MHA1
Pingpank, JF1
Holtzman, MP1
Bahary, N1
Hogg, ME1
Zeh, HJ1
Geller, DA1
Wallis Marsh, J1
Tsung, A1
Zureikat, AH1
Chakedis, J1
Beal, EW1
Sun, S1
Galo, J1
Chafitz, A1
Davidson, G1
Reardon, J1
Dillhoff, M1
Pawlik, TM1
Abdel-Misih, S1
Bloomston, M1
Schmidt, CR1
Buisman, FE1
Homs, MYV1
Grünhagen, DJ1
Filipe, WF1
Bennink, RJ1
Besselink, MGH1
Borel Rinkes, IHM1
Bruijnen, RCG1
Cercek, A1
D'Angelica, MI1
van Delden, OM1
Donswijk, ML1
van Doorn, L1
Doornebosch, PG1
Emmering, J1
Erdmann, JI1
IJzerman, NS1
Grootscholten, C1
Hagendoorn, J1
Kemeny, NE2
Kingham, TP1
Klompenhouwer, EG1
Kok, NFM1
Koolen, S1
Kuhlmann, KFD1
Kuiper, MC1
Lam, MGE1
Mathijssen, RHJ1
Moelker, A1
Oomen-de Hoop, E1
Punt, CJA1
Te Riele, WW1
Roodhart, JML1
Swijnenburg, RJ1
Prevoo, W1
Tanis, PJ1
Vermaas, M1
Versleijen, MWJ1
Veuger, FP1
Weterman, MJ1
Verhoef, C1
Groot Koerkamp, B1
Kang, YK2
Chang, HM2
Yook, JH2
Ryu, MH2
Park, I1
Min, YJ1
Zang, DY2
Kim, GY1
Yang, DH2
Jang, SJ2
Park, YS2
Lee, JL2
Kim, TW2
Oh, ST1
Park, BK1
Jung, HY2
Kim, BS2
Yoshino, S1
Furuya, T1
Shimizu, R1
Ozasa, H3
Nishimura, T1
Fukuda, S1
Kawaoka, T1
Hazama, S1
Oka, M1
Kwa, M1
Edwards, S1
Downey, A1
Reich, E1
Wallach, R1
Curtin, J1
Muggia, F2
Yoo, C1
Lee, YJ1
Kim, JH1
Huang, PY1
Zeng, Q1
Cao, KJ1
Guo, X1
Guo, L1
Mo, HY1
Wu, PH1
Qian, CN1
Mai, HQ1
Hong, MH1
Nishimura, R2
Tominaga, T5
Kimura, M4
Yanagita, Y1
Tamaki, N1
Asaishi, K1
Okamoto, Y2
Okuyama, N2
Takeuchi, H1
Inaba, M1
Doi, T1
Sakurai, T2
Umemura, T1
Jinta, E1
Suzuma, T1
Yoshimura, G1
Shimizu, S1
Huh, JW1
Kim, HR1
Yoshikawa, T1
Tsuburaya, A1
Shimada, K2
Sato, A2
Takahashi, M2
Koizumi, W1
Yoshizawa, Y1
Nabeshima, K1
Hataya, K1
Kobayashi, O1
Samaras, P1
Breitenstein, S1
Haile, SR1
Stenner-Liewen, F1
Heinrich, S1
Feilchenfeldt, J1
Renner, C1
Knuth, A1
Pestalozzi, BC1
Clavien, PA1
Geng, S1
Wang, T1
Takeyoshi, I1
Makita, F1
Tanahashi, Y1
Iwazaki, S1
Ogawa, T1
Tomizawa, N1
Nakamura, S1
Ishikawa, H2
Ohya, T1
Kakinuma, S1
Nakagami, K1
Sato, Y1
Koyano, T1
Roppongi, T1
Izumi, M1
Kobayashi, J1
Kawate, S1
Sunose, Y1
Kobayashi, M1
Yamada, T2
Sakamoto, I1
Bolton, JS1
O'Connell, MJ1
Mahoney, MR1
Farr, GH1
Fitch, TR1
Maples, WJ1
Nagorney, DM1
Rubin, J1
Fuloria, J1
Steen, PD1
Alberts, SR1
Cohen, DJ1
Newman, E1
Iqbal, S1
Chang, RY1
Potmesil, M1
Ryan, T1
Donahue, B1
Chandra, A1
Liu, M1
Utate, M1
Hiotis, S1
Pachter, LH1
Hochster, H1
Yakabe, T1
Noshiro, H1
Ikeda, O1
Miyoshi, A1
Kitajima, Y1
Satoh, S1
Wagner, PL1
Jones, D1
Aronova, A1
Shia, J1
Weiser, MR1
Temple, LK1
Chung, KY1
O'Reilly, EM1
Kelsen, D1
Paty, PB1
Nash, GM1
Bilchik, AJ2
Wood, TF1
Chawla, SP1
Rose, DM1
Chung, MH1
Stern, SS1
Foshag, LJ1
Ramming, KP1
Nakamachi, M1
Ushio, J1
Yamamoto, W1
Kurihara, M1
Matsukawa, M1
Sawada, T1
Kou, Y1
Wang, H1
Li, H1
Zang, M1
Xu, F1
Kato, T1
Kikkawa, N2
Tsujie, M1
Iijima, S1
Handa, R1
Naoi, Y1
Oshima, S1
Yamamoto, H2
Kurokawa, E1
Suzuki, O1
Sekishita, Y1
Shiono, T1
Kondo, S1
Kato, H1
Miyoshi, K1
Ohtsuka, S1
Inagaki, M1
Ohsaki, T1
Fuchimoto, S1
Yumura, M1
Nakagawa, T1
Iba, T1
Kidokoro, A1
Fukunaga, M1
Sugiyama, K1
Aihara, N1
Suda, M1
Yoshitani, S1
Imaizumi, H1
Kuroda, M1
Yokoi, M1
Tanaka, Y1
Harada, H1
Kosaka, T1
Takashima, S2
Matsuyama, H1
Baba, Y1
Shimabukuro, T1
Uchiyama, K1
Aoki, A1
Suga, A1
Jojima, K1
Suyama, K1
Yamamoto, N1
Naito, K1
Fujino, S1
Kan, N1
Lee, CJ1
Inamoto, T1
Mise, K1
Sawai, S1
Okamoto, M1
Nishimura, S1
Hori, T1
Maruhashi, K1
Yamauchi, A1
Fujii, K1
Mitsumori, M1
Higashide, S1
Takemoto, Y1
Okamura, T1
Ogata, Y2
Matono, K2
Sasatomi, T1
Ishibashi, N2
Ohkita, A1
Mizobe, T2
Ogo, S1
Ikeda, S2
Shirouzu, K2
Tsubono, M1
Kaneko, I1
Kii, E1
Murata, T1
Kamimura, K1
Deguchi, Y1
Yasumizu, R1
Tanaka, K2
Noura, S1
Ohue, M1
Takachi, K1
Kishi, K1
Eguchi, H1
Miyashiro, I1
Yano, M1
Ohigashi, H2
Sasaki, Y2
Ishikawa, O2
Imaoka, S3
Kameyama, M2
Murata, K1
Mizutani, S1
Oyama, T1
Hatanaka, N1
Uchikoshi, F1
Yoshidome, K1
Tori, M1
Ueshima, S1
Okuma, K1
Hiraoka, K1
Yamagami, Y1
Takahashi, H1
Sueyoshi, K1
Taira, M1
Nakahara, M1
Nakao, K1
Mori, S1
Akagi, Y1
Murakami, H1
Ikeda, M1
Sonoo, H2
Kurebayashi, J1
Morimoto, T3
Tangoku, A1
Komaki, K2
Kataoka, T1
Ishiguro, K1
Yoshizawa, K1
Gotoh, J1
Akabane, H1
Kita, K1
Fujiyoshi, M1
Hirokata, G1
Imai, K1
Kawai, T1
Yanagida, N1
Nakano, S1
Arai, W1
Hosoya, Y1
Hyodo, M1
Haruta, H1
Kurashina, K1
Saito, S2
Hirashima, Y1
Yokoyama, T1
Zuiki, T1
Sakuma, K1
Yasuda, Y1
Nagai, H1
Murakami, S1
Yamamoto, Y1
Takiuchi, H1
Goto, M1
Imamura, H1
Furukawa, H1
Imano, M1
Imamoto, H1
Kimura, Y1
Ishida, H1
Fujitani, K1
Narahara, H1
Shimokawa, T1
Nakata, E1
Okajima, K1
Ishida, Y1
Munetomo, Y1
Gotoh, K1
Toyohara, M1
Miyazaki, H1
Matsunaga, S1
Maeura, Y2
Fujimura, T1
Kelsen, DP1
Saltz, L1
Cohen, AM1
Yao, TJ1
Enker, W1
Tong, W1
Tao, Y1
Bertino, JR1
Takahashi, K1
Mori, T1
Takahashi, T1
Nakamori, S1
Yasuda, T1
Nakano, H1
Hiratsuka, M1
Kabuto, T1
Yamada, Y1
Tsushima, K2
Sakata, Y2
Ito, T1
Sugimoto, N1
Ogasawara, H2
Tamura, Y2
Moriya, N1
Komatsu, Y1
Taguchi, T2
Sakai, K1
Irie, K1
Terasawa, T2
Shimoyama, T1
Iwanaga, T2
Fukuda, I1
Okumura, S1
Yasutake, K3
Enomoto, K1
Abe, R1
Iino, Y1
Koyama, H2
Nomura, Y1
Abe, O2
Nakazato, H2
Nishisaki, H1
Oya, M2
Nakashima, T1
Hasegawa, H1
Horita, K1
Yoshida, R1
Nakanishi, Y1
Abo, K1
Koida, T1
Sekihara, M1
Crookes, P1
Leichman, CG1
Leichman, L1
Tan, M1
Laine, L1
Stain, S1
Baranda, J1
Casagrande, Y1
Groshen, S2
Silberman, H1
Muggia, FM1
Jeffers, S1
Muderspach, L1
Roman, L1
Rosales, R1
Safra, T1
Morrow, CP1
Katsumata, K1
Yamamoto, K1
Shibata, K1
Murano, A1
Kawasaki, M1
Moriwaki, R1
Nagakawa, Y1
Ogata, T1
Koyanagi, Y1
Kusama, M1
Takatsuka, Y2
Shin, E1
Davies, MM1
Fordy, C1
Burke, D1
Allen-Mersh, TG1
González Barón, M1
Inoue, K1
Tabei, T2
Suemasu, K1
Higashi, Y1
Kurosumi, M1
Senoo, T1
Nishiki, M1
Tashiro, H1
Takahashi, I1
Yamamura, S1
Ishikawa, T1
Yanaga, K1
Wakasugi, K1
Matsusaka, T1
Kume, K1
Kokufu, I1
Taniguchi, H1
Kim, YH1
Fukuda, K1
Yamamoto, M1
Yano, T1
Yamada, K1
Kitano, H1
Takiguchi, N1
Nakajima, N1
Saitoh, N1
Fujimoto, S1
Hara, Y1
Kawasaki, T1
Yabata, E1
Gen, T1
Jibiki, M1
Kudoh, A1
Noguchi, N1
Igarashi, K1
Kikuchi, M1
Matsuoka, T1
Nomizu, T1
Yabuta, T1
Katagata, N1
Watanabe, F1
Yamaki, Y1
Tsuchiya, A1
Takenoshita, S1
Tono, T1
Monden, T1
Kubota, Y1
Noguchi, S2
Masuda, M1
Hosaka, M1
Noguchi, K1
Sasaki, K1
Miura, T1
Ikeda, I1
Kondo, I1
Senga, Y1
Moriyama, M1
Fukushima, S1
Ebato, T1
Fukuda, M1
Kitami, K1
Fukuoka, H1
Sato, K1
Hirokawa, M1
Chiba, K1
Kanno, H1
Miyai, K1
Iwata, H1
Mizutani, M1
Iwase, T1
Murai, H1
Miura, S1
Min, JS1
Kim, NK1
Park, JK1
Yun, SH1
Noh, JK1
Sato , K1
Hiraide, H1
Tamakuma, S1
Maruyama, M1
Touma, M1
Okamura, H1
Matsumoto, F1
Akao, S1
Yagi, Y1
Mochizuki, H1
Aoyama, H1
Iwase, H1
Mitsuyama, S1
Asaga, T1
Kemeny, MM1
Adak, S1
Gray, B1
Macdonald, JS1
Smith, T1
Lipsitz, S1
Sigurdson, ER1
O'Dwyer, PJ1
Benson, AB1
Miyamoto, H1
Yoshida, S1
Imatomi, M1
Saitoh, T1
Nakata, A1
Dizon, DS1
Mizuno, Y1
Makino, N1
Matsumoto, K1
Fujimura, N1
Yamamoto, E1
Ishida, C1
Koyama, S1
Naitoh, M1
Maezato, K1
Matsukawa, Y1
Yayoi, E1
Miyauchi, K2
Aikawa, T1
Hirai, T1
Kotsuma, Y1
Imamura, Y1
Yoshimura, Y1
Matsushita, K1
Tokisue, M1
Ohno, S1
Masuda, T1
Nishizawa, Y1
Inaji, H1
Itoh, T1
Furukohri, N1
Saitoh, S1
Baba, T1
Munakata, A1
Yoshida, Y2
Ogawa, N1
Hoshino, A1
Ohara, K1
Kamiya, O1
Nagata, K1
Ono, Y1
Kawakubo, A1
Ozaki, Y1
Suzuki, A1
Ogasawara, T1
Sugiura, I1
Sears, HF1
Shen, JW1
Herlyn, M1
Atkinson, B1
Engstrom, PF1
Koprowski, H1
Goodman, HM1
Dottino, PR1
Kredenster, D1
Mark, M1
Runowicz, C1
Cohen, CJ1
Welch, DR1
Aeed, PA1
Estrada, J1
Yamakawa, T1
Tanaka, T1
Konishi, Y1
Uomine, Y1
Miki, H1
Ooshimo, K1
Monden, Y1
Taylor, I1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology[NCT03092518]Phase 227 participants (Actual)Interventional2017-06-05Active, not recruiting
A Multicenter and Prospective Clinical Trial of Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma[NCT04522050]Phase 165 participants (Anticipated)Interventional2018-10-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for floxuridine and Local Neoplasm Recurrence

ArticleYear
Arterial chemotherapy as adjuvant and palliative treatment of hepatic colorectal metastases: an update.
    Surgical oncology clinics of North America, 2003, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Combined Modality Therapy; Flox

2003
[Treatment strategy for recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cyclophospha

1998
[Oral fluoropyrimidines in oncology].
    Anales de la Real Academia Nacional de Medicina, 1998, Volume: 115, Issue:3

    Topics: Administration, Oral; Antidotes; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplas

1998
[The role of prophylactic hepatic arterial infusion chemotherapy after potentially curative resection of hepatic metastases from colorectal cancer].
    Nihon Geka Gakkai zasshi, 2000, Volume: 101, Issue:8

    Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Floxuridine; Fluorouracil; Hepatectomy; Hepat

2000
Intrahepatic arterial infusion of chemotherapy: clinical results.
    Seminars in oncology, 2002, Volume: 29, Issue:2

    Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Combined Modality Therapy; Floxuridine; Fluor

2002
[A comparative study with 5'-DFUR alone or in combination with tamoxifen (TAM) or medroxyprogesterone acetate (MPA) for advanced or recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Drug Therapy, Combination; Female; Flox

1992
Adjuvant cytotoxic chemotherapy for colorectal cancer: the present position.
    The Australian and New Zealand journal of surgery, 1988, Volume: 58, Issue:9

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Combine

1988

Trials

36 trials available for floxuridine and Local Neoplasm Recurrence

ArticleYear
Efficacies of FAEV and EMA/CO regimens as primary treatment for gestational trophoblastic neoplasia.
    British journal of cancer, 2022, Volume: 127, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dactinomycin; Etoposide; Female; Floxuridine; Gestat

2022
Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases - the multicenter randomized controlled PUMP trial.
    BMC cancer, 2019, Apr-05, Volume: 19, Issue:1

    Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic;

2019
Adjuvant chemotherapy for gastric cancer: a randomised phase 3 trial of mitomycin-C plus either short-term doxifluridine or long-term doxifluridine plus cisplatin after curative D2 gastrectomy (AMC0201).
    British journal of cancer, 2013, Apr-02, Volume: 108, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Floxurid

2013
Combination phase II study of weekly paclitaxel and 5'-DFUR for unresectable or recurrent gastric cancer.
    Anticancer research, 2013, Volume: 33, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic;

2013
Enhanced efficacy of postoperative adjuvant chemotherapy in advanced gastric cancer: results from a phase 3 randomized trial (AMC0101).
    Cancer chemotherapy and pharmacology, 2014, Volume: 73, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Fema

2014
Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:13

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy, Ad

2015
Efficacy of doxifluridine combined with weekly paclitaxel therapy in the treatment of advanced or recurrent breast cancer: results of the JMTO BC01 phase II trial.
    Anti-cancer drugs, 2008, Volume: 19, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival

2008
A phase II study of doxifluridine and docetaxel combination chemotherapy for advanced or recurrent gastric cancer.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2009, Volume: 12, Issue:4

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surv

2009
A phase II study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/recurrent gastric cancer.
    Anticancer research, 2011, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation

2011
Hepatic arterial infusion and systemic chemotherapy after multiple metastasectomy in patients with colorectal carcinoma metastatic to the liver: a North Central Cancer Treatment Group (NCCTG) phase II study, 92-46-52.
    Clinical colorectal cancer, 2012, Volume: 11, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neop

2012
Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil.
    Clinical colorectal cancer, 2001, Volume: 1, Issue:1

    Topics: Antimetabolites, Antineoplastic; Camptothecin; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regiona

2001
[Prevention and treatment of bladder tumors recurrence with furtulon].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2000, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2000
The efficacy of long-term oral chemotherapy with 5'-deoxy-5-fluorouridine and cyclophosphamide for recurrent breast cancer.
    International journal of clinical oncology, 2004, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast

2004
Novel prophylactic effect of doxifluridine in superficial bladder cancer.
    Scandinavian journal of urology and nephrology, 2004, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Carcinoma, Transitional Cell; Cystectomy; Dose

2004
[Bi-weekly chemotherapy with medium-dose docetaxel for advanced and recurrent breast cancers (The 15th study of Keiji Breast Cancer Study Group)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:5

    Topics: Adult; Aged; Alopecia; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bone Marr

2005
[Evaluation of safety and efficacy for bi-weekly Docetaxel and 5'-DFUR combination therapy in patients with advanced or recurrent breast cancer--Phase I study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:6

    Topics: Administration, Oral; Aged; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Bone Ne

2006
Multi-center phase II study for combination therapy with paclitaxel/doxifluridine to treat advanced/recurrent gastric cancer showing resistance to S-1 (OGSG 0302).
    Japanese journal of clinical oncology, 2008, Volume: 38, Issue:3

    Topics: Adenocarcinoma; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Disease-Free

2008
[Combination therapy of high dose 5'-DFUR+MMC for advanced or recurrent gastric cancer. 5'-DFUR Joint Research Group in the Osaka District for Gastric Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Administration Schedule;

1995
A phase I trial of immediate postoperative intraperitoneal floxuridine and leucovorin plus systemic 5-fluorouracil and levamisole after resection of high risk colon cancer.
    Cancer, 1994, Oct-15, Volume: 74, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Combined Modality Th

1994
[Hepatic arterial infusion after hepatectomy for liver metastases of colorectal carcinoma to prevent residual hepatic recurrence].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Female; Floxuridine; Flu

1994
[Adjuvant chemo-endocrine chemotherapy with gastrin antagonist after resection of liver metastasis in colorectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:13

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adj

1994
[Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy]
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alopecia; Anorexia; Antineoplastic Combined Ch

1994
[A randomized controlled study of maintenance therapy with (2"R)-4'-O-tetrahydropyranyladriamycin for advanced and recurrent breast cancer. Clinical Study Group of THP for Breast Cancer in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:7

    Topics: Adult; Alopecia; Anorexia; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protoco

1996
Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report.
    Cancer, 1997, May-01, Volume: 79, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

1997
Phase I/II study of intraperitoneal floxuridine and platinums (cisplatin and/or carboplatin).
    Gynecologic oncology, 1997, Volume: 66, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carbop

1997
[Therapeutic efficacy of pirarubicin cyclophosphamide and doxifluridine in advanced and metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dox

1999
[Usefulness of low dose 5'-DFUR (5'-deoxy-5-fluorouridine) for advanced or recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:7

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Drug Adm

1999
[Effects of DAC (doxifluridine, adriamycin, cyclophosphamide) chemotherapy in advanced breast cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:6

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclop

1999
A phase III randomized study comparing oral doxifluridine and oral 5-fluorouracil after curative resection of gastric cancer.
    International journal of oncology, 2000, Volume: 16, Issue:5

    Topics: Administration, Oral; Adult; Aged; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Floxuridin

2000
[5'-DFUR chemoprophylaxis in superficial bladder cancer. Kanagawa Urology 5'-DFUR Study Group].
    Hinyokika kiyo. Acta urologica Japonica, 2000, Volume: 46, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Flo

2000
A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer.
    Annals of surgical oncology, 2000, Volume: 7, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disea

2000
5'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer.
    Breast cancer (Tokyo, Japan), 2001, Volume: 8, Issue:1

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neo

2001
[A phase I study of docetaxel (TXT) and doxifluridine (5'-DFUR) combination therapy in patients with advanced and recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2001, Volume: 28, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Drug Admin

2001
Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy--an intergroup study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Mar-15, Volume: 20, Issue:6

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasm

2002
[Clinical trial of a new fluorinated pyrimidine, 5'-deoxy-5-fluorouridine (5'-DFUR)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 1

    Topics: Adult; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Clinical Trials as Topic; Drug Admin

1986
Continuous infusion fluoropyrimidines as salvage therapy for patients with advanced ovarian carcinoma.
    Gynecologic oncology, 1988, Volume: 29, Issue:3

    Topics: Adult; Aged; Cyclophosphamide; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Mi

1988

Other Studies

42 other studies available for floxuridine and Local Neoplasm Recurrence

ArticleYear
Effectiveness of Hepatic Artery Infusion (HAI) Versus Selective Internal Radiation Therapy (Y90) for Pretreated Isolated Unresectable Colorectal Liver Metastases (IU-CRCLM).
    Annals of surgical oncology, 2018, Volume: 25, Issue:2

    Topics: Antimetabolites, Antineoplastic; Brachytherapy; Colorectal Neoplasms; Combined Modality Therapy; Emb

2018
Implementation and early outcomes for a surgeon-directed hepatic arterial infusion pump program for colorectal liver metastases.
    Journal of surgical oncology, 2018, Volume: 118, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Body Fat Distribution; Colorectal N

2018
Ovarian cancer in BRCA mutation carriers: improved outcome after intraperitoneal (IP) cisplatin.
    Annals of surgical oncology, 2014, Volume: 21, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Carboplatin; Cis

2014
[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide (DMpC) combination therapy is effective against recurrent triple negative breast cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Floxurid

2008
Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0?
    Journal of surgical oncology, 2009, Oct-01, Volume: 100, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv

2009
Selective intra-arterial chemotherapy with floxuridine as second- or third-line approach in patients with unresectable colorectal liver metastases.
    Annals of surgical oncology, 2011, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Colorectal Neoplasms; F

2011
Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dactinomycin; Dru

2011
Postoperative intraperitoneal 5-fluoro-2'-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma.
    Annals of surgical oncology, 2012, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem

2012
Second-line chemotherapy with paclitaxel and doxifluridine after failure of S-1 in elderly patients with unresectable advanced or recurrent gastric cancer.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female;

2011
Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasis.
    Diseases of the colon and rectum, 2012, Volume: 55, Issue:4

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal N

2012
Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2002, Volume: 5, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm

2002
[Evaluation of weekly paclitaxel and doxifluridine (5'-DFUR) combination therapy in patients with advanced or recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dr

2003
[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat

2003
Positive response to oral chemoendocrine combination therapy using 5"-deoxy-5-fluorouridine for locally advanced breast cancer with carcinomatous pleurisy: report of a case.
    Surgery today, 2003, Volume: 33, Issue:12

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Breast Neoplasms; Drug Therapy, Combination;

2003
[Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:10

    Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas

2004
[A case of long-term survival after chemo-radiation for postoperative local recurrence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy

2004
The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo

2006
[Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:9

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche

2005
[A case of chemoradiation with tissue expander for local reccurence of rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Adenocarcinoma, Mucinous; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antine

2005
[Combined chemotherapy with weekly Paclitaxel and doxifluridine for advanced and recurrent gastric cancers].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; F

2006
The expression of vascular endothelial growth factor determines the efficacy of post-operative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
    Oncology reports, 2006, Volume: 15, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo

2006
[A case of local recurrence of rectal cancer in long-term responding to combined therapy of low-dose CPT-11 and 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptoth

2006
Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1.
    International journal of clinical oncology, 2007, Volume: 12, Issue:2

    Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Combine

2007
[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine

2007
[Combination therapy of high dose doxifluridine (5'-DFUR)+mitomycin C (MMC) for advanced or recurrent colorectal cancer. Joint Research Group in the Osaka Area for Combination Therapy of 5'-DFUR with Other Drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms

1993
[Combined chemotherapy with MMC, ADM, CDDP, etoposide (VP-16) and 5'-DFUR, (MACVD therapy) as a second-line chemotherapy for metastatic gastric cancer: three cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Floxuridi

1996
[A case of recurrent breast cancer responding to long-term treatment with 5'-DFUR combined with MPA].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:9

    Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Ad

1996
[Efficacy of combination chemotherapy with mitoxantrone, vincristine, doxifluridine and prednisolone for recurrence of breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:15

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

1997
Management of symptomatic locoregional recurrence during regional chemotherapy for colorectal liver metastases.
    The British journal of surgery, 1998, Volume: 85, Issue:3

    Topics: Abdominal Neoplasms; Antimetabolites, Antineoplastic; Chemotherapy, Cancer, Regional Perfusion; Colo

1998
[A case of adriamycin and methotrexate-resistant recurrent breast cancer treated with doxifluridine and mitomycin C].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:9

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco

1999
[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

2000
[Chemotherapy with mitoxantrone for the treatment of recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Drug Administratio

2000
A case of metastatic breast cancer achieving complete response by combination therapy with 5'-deoxy-5-fluorouridine and cyclophosphamide.
    Breast cancer (Tokyo, Japan), 2000, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Breast Neoplasms; Carcinoma, Duct

2000
[Successful treatment of advanced recurent breast cancer using DMpC therapy as maintenance therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cyclophospha

2002
[A case of recurrent esophageal cancer maintaining complete long-term response after 5'-DFUR and ftorafur administrations].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:4

    Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Esophageal Neoplasms; Floxurid

1992
[A study of combined chemotherapy with MMC, ADM, CDDP, etoposide (VP-16), 5'DFUR (MAC-VD therapy) in advanced cancer and local relapse of the stomach].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxoru

1990
[Combination therapy with 5'DFUR and MPA as a second line treatment for advanced/recurrent breast cancer].
    Nihon Gan Chiryo Gakkai shi, 1990, Mar-20, Volume: 25, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Floxuridine;

1990
[Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Ne

1989
[A comparative study of 5'-DFUR and tegafur in recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:10

    Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Capsules; Diar

1985
Circulating tumor markers and assessment of response to intrahepatic chemotherapy of colon carcinoma.
    American journal of clinical oncology, 1985, Volume: 8, Issue:2

    Topics: Adult; Aged; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Carcinoembryonic Antigen;

1985
Development and characterization of a rat model for locally recurring mammary tumors: sensitivities to 5-fluoro-2'-deoxyuridine, adriamycin, and X-irradiation.
    Cancer research, 1988, Aug-15, Volume: 48, Issue:16

    Topics: Animals; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Femal

1988
[Clinical trial of 5'-DFUR in patients with recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:10

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Female; Floxuridi

1988