floxuridine has been researched along with Liver Dysfunction in 4 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The pharmacokinetic analysis of gemcitabine and dFdU was performed with high-performance liquid chromatography-tandem mass spectrometry assay in cycles 1 and 2." | 1.35 | Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function. ( Citro, G; Cognetti, F; Colantonio, S; Contestabile, M; Di Segni, S; Felici, A; Milella, M; Nuvoli, B; Sacconi, A; Sperduti, I; Zaratti, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Felici, A | 1 |
| Di Segni, S | 1 |
| Milella, M | 1 |
| Colantonio, S | 1 |
| Sperduti, I | 1 |
| Nuvoli, B | 1 |
| Contestabile, M | 1 |
| Sacconi, A | 1 |
| Zaratti, M | 1 |
| Citro, G | 1 |
| Cognetti, F | 1 |
| Byfield, JE | 1 |
| Barone, RM | 1 |
| Frankel, SS | 1 |
| Sharp, TR | 1 |
| Soon, PS | 1 |
| Glenn, D | 1 |
| Jorgensen, J | 1 |
| Morris, DL | 1 |
| Kemeny, NE | 1 |
1 review available for floxuridine and Liver Dysfunction
| Article | Year |
|---|---|
Is hepatic infusion of chemotherapy effective treatment for liver metastases? Yes!
Topics: Actuarial Analysis; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dexamethasone; Fl | 1992 |
1 trial available for floxuridine and Liver Dysfunction
| Article | Year |
|---|---|
Is hepatic infusion of chemotherapy effective treatment for liver metastases? Yes!
Topics: Actuarial Analysis; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dexamethasone; Fl | 1992 |
3 other studies available for floxuridine and Liver Dysfunction
| Article | Year |
|---|---|
Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function.
Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Biliary Tract Neopla | 2009 |
Treatment with combined intra-arterial 5-FUdR infusion and whole-liver radiation for colon carcinoma metastatic to the liver. Preliminary results.
Topics: Adult; Colonic Neoplasms; Combined Modality Therapy; Drug Implants; Evaluation Studies as Topic; Flo | 1984 |
Fluorodeoxyuridine causes bilomas after hepatic cryotherapy.
Topics: Antimetabolites, Antineoplastic; Bile; Cryotherapy; Floxuridine; Hepatectomy; Humans; Infusions, Int | 1998 |