floxuridine has been researched along with Kidney Failure in 2 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Plasma concentration data were pooled and analyzed using a population pharmacokinetic program (NONMEM)." | 2.71 | Gemcitabine in patients with solid tumors and renal impairment: a pharmacokinetic phase I study. ( Delaloge, S; Di Palma, M; Forgue, ST; Le Chevalier, T; Llombart, A; Ni, L; Tourani, JM; Turpin, F, 2004) |
| "Gemcitabine was rapidly eliminated from plasma even in patients with renal dysfunction." | 1.35 | Measurement of plasma concentration of gemcitabine and its metabolite dFdU in hemodialysis patients with advanced urothelial cancer. ( Hirobe, M; Itoh, T; Kunishima, Y; Masumori, N; Takayanagi, A; Takeuchi, M; Tsukamoto, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Delaloge, S | 1 |
| Llombart, A | 1 |
| Di Palma, M | 1 |
| Tourani, JM | 1 |
| Turpin, F | 1 |
| Ni, L | 1 |
| Forgue, ST | 1 |
| Le Chevalier, T | 1 |
| Masumori, N | 1 |
| Kunishima, Y | 1 |
| Hirobe, M | 1 |
| Takeuchi, M | 1 |
| Takayanagi, A | 1 |
| Tsukamoto, T | 1 |
| Itoh, T | 1 |
1 trial available for floxuridine and Kidney Failure
| Article | Year |
|---|---|
Gemcitabine in patients with solid tumors and renal impairment: a pharmacokinetic phase I study.
Topics: Antimetabolites, Antineoplastic; Deoxycytidine; Female; Floxuridine; Gemcitabine; Humans; Male; Midd | 2004 |
1 other study available for floxuridine and Kidney Failure
| Article | Year |
|---|---|
Measurement of plasma concentration of gemcitabine and its metabolite dFdU in hemodialysis patients with advanced urothelial cancer.
Topics: Antimetabolites, Antineoplastic; Area Under Curve; Bone Neoplasms; Cystectomy; Deoxycytidine; Fatal | 2008 |