floxuridine has been researched along with Invasiveness, Neoplasm in 17 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemcitabine and capecitabine are nucleoside analogues used in chemotherapy strategies for the treatment of breast cancer." | 3.71 | Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers. ( Baldwin, SA; Cass, CE; Clarke, ML; Coupland, RW; Dabbagh, L; Jennings, LL; Koski, SL; Mackey, JR; Santos, CL; Vsianska, M; Young, JD, 2002) |
| "The data on 307 patients with colorectal cancer at stage II or III, who underwent potentially curative resection with lymphadenectomy, were reviewed." | 1.33 | The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer. ( Ikeda, S; Ishibashi, N; Matono, K; Mizobe, T; Ogata, Y; Ogo, S; Ohkita, A; Ozasa, H; Sasatomi, T; Shirouzu, K, 2006) |
| "With a diagnosis of advanced breast cancer with skin invasion, she underwent right mastectomy with a free skin graft." | 1.32 | Massive mucinous carcinoma of the breast untreated for 6 years. ( Sakaguchi, K; Tsuchie, K; Yoneyama, F, 2003) |
| "The mean activity in 37 bladder cancers and in 8 samples of normal bladder epithelial tissue was 108." | 1.30 | Thymidine phosphorylase activity in human bladder cancer: difference between superficial and invasive cancer. ( Hosaka, M; Kubota, Y; Matsuzaki, J; Miura, T; Moriyama, M; Noguchi, S; Takebayashi, S, 1997) |
| "She was diagnosed as having an advanced gastric cancer, which was unresectable because of liver metastasis, esophageal invasion and paraaortic lymph node metastasis." | 1.29 | [Unresectable gastric cancer followed by remarkably effective tumor disappearance and good quality of life for 10 months after CDDP/5'-DFUR combination chemotherapy--a case report]. ( Hoshino, K; Ikeda, H; Kamoshita, N; Kobayashi, J; Koyama, T; Morishita, Y; Nakamura, M; Tanaka, T, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SG | 1 |
| Hwang, SH | 1 |
| Takizawa, M | 1 |
| Hirano, M | 1 |
| Murakami, N | 1 |
| Uno, Y | 1 |
| Kikuchi, T | 1 |
| Nozawa, H | 1 |
| Hara, T | 1 |
| Asaumi, Y | 1 |
| Kikkawa, H | 1 |
| Yoneyama, F | 1 |
| Tsuchie, K | 1 |
| Sakaguchi, K | 1 |
| Nakagawa, H | 1 |
| Yoshioka, K | 1 |
| Miyahara, E | 1 |
| Fukushima, Y | 1 |
| Tamura, M | 1 |
| Itoh, K | 1 |
| Ogata, Y | 2 |
| Matono, K | 2 |
| Sasatomi, T | 1 |
| Ishibashi, N | 2 |
| Ohkita, A | 1 |
| Mizobe, T | 2 |
| Ogo, S | 1 |
| Ikeda, S | 2 |
| Ozasa, H | 2 |
| Shirouzu, K | 2 |
| Fukuda, Y | 1 |
| Fujio, N | 1 |
| Ihara, T | 1 |
| Takatori, H | 1 |
| Tsukazaki, T | 1 |
| Koyama, I | 1 |
| Tsukazaki, Y | 1 |
| Osugi, H | 1 |
| Mori, S | 1 |
| Akagi, Y | 1 |
| Murakami, H | 1 |
| Tajima, H | 1 |
| Matsuki, N | 2 |
| Takeda, T | 1 |
| Horichi, H | 1 |
| Kumaki, T | 1 |
| Shima, K | 1 |
| Tohyama, Y | 1 |
| Kojima, K | 1 |
| Shirota, Y | 1 |
| Yasuda, S | 1 |
| Nakamura, T | 1 |
| Nihei, Z | 1 |
| Hirayama, R | 1 |
| Mishima, Y | 1 |
| Hoshino, K | 1 |
| Nakamura, M | 1 |
| Kamoshita, N | 1 |
| Ikeda, H | 1 |
| Kobayashi, J | 1 |
| Tanaka, T | 1 |
| Koyama, T | 1 |
| Morishita, Y | 1 |
| Nishimura, G | 1 |
| Izumi, R | 1 |
| Takeyama, S | 1 |
| Konishi, K | 1 |
| Fujita, H | 1 |
| Miyata, R | 1 |
| Sasaki, T | 1 |
| Kojima, Y | 1 |
| Takada, M | 1 |
| Takita, Y | 1 |
| Kanno, M | 1 |
| Ueno, K | 1 |
| Mura, T | 1 |
| Asano, K | 1 |
| Syouji, M | 1 |
| Yamazaki, H | 1 |
| Ooto, T | 1 |
| Ueda, H | 1 |
| Takigawa, Y | 1 |
| Sawa, T | 1 |
| Miyazaki, I | 1 |
| Ueda, M | 2 |
| Ueki, M | 2 |
| Terai, Y | 2 |
| Morimoto, A | 1 |
| Fujii, H | 2 |
| Yoshizawa, K | 2 |
| Yanagihara, T | 2 |
| Kubota, Y | 1 |
| Miura, T | 1 |
| Moriyama, M | 1 |
| Noguchi, S | 1 |
| Matsuzaki, J | 1 |
| Takebayashi, S | 1 |
| Hosaka, M | 1 |
| Kumagai, K | 1 |
| Ueki, K | 1 |
| Soga, H | 1 |
| Hayashida, H | 1 |
| Yoshiki, T | 1 |
| Higuchi, K | 1 |
| Okada, Y | 1 |
| Kobayashi, T | 1 |
| Kimura, T | 1 |
| Mackey, JR | 1 |
| Jennings, LL | 1 |
| Clarke, ML | 1 |
| Santos, CL | 1 |
| Dabbagh, L | 1 |
| Vsianska, M | 1 |
| Koski, SL | 1 |
| Coupland, RW | 1 |
| Baldwin, SA | 1 |
| Young, JD | 1 |
| Cass, CE | 1 |
1 trial available for floxuridine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
[Long-term outcome of preoperative chemotherapy with 5'-deoxy-5-fluorouridine (5'-DFUR) for gastric cancer].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Female; Floxuridine; Follow-Up Studies; Humans; M | 2000 |
16 other studies available for floxuridine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape | 2016 |
[A case of recurrent gastric cancer that responded dramatically to docetaxel and 5'-DFUR combination chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Administr | 2002 |
Massive mucinous carcinoma of the breast untreated for 6 years.
Topics: Adenocarcinoma, Mucinous; Biopsy, Needle; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Floxurid | 2003 |
Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.
Topics: Actins; Agar; Amides; Animals; Brain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cells, Culture | 2005 |
The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo | 2006 |
[A case of advanced gastric cancer with direct invasion of the transverse colon responding to paclitaxel/5'-DFUR combined therapy].
Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Colon, Transverse; Coloni | 2005 |
The expression of vascular endothelial growth factor determines the efficacy of post-operative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemo | 2006 |
[A case of cutaneous and brain metastasis of gastric carcinoma, treated effectively by chemotherapy with CDDP, MMC, etoposide and 5'-DFUR].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Ne | 1994 |
[A case of nonresectable advanced gastric cancer responding to combined chemotherapy with 5'-DFUR, CDDP, and MMC].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Flox | 1996 |
[Unresectable gastric cancer followed by remarkably effective tumor disappearance and good quality of life for 10 months after CDDP/5'-DFUR combination chemotherapy--a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Cisplatin; Esoph | 1996 |
[Effect on 5'-deoxy-5-fluorouridine (5'-DFUR) of pyrimidine nucleoside phosphorylase (PyNPase), matrix metalloprotease and serum IAP values. Hokuriku Colorectal Cancer Chemotherapy Study Group].
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Extracellular Matrix; Female; Floxuridine; Hu | 1997 |
Stimulatory effects of EGF and TGF-alpha on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in uterine cervical-carcinoma SKG-IIIb cells.
Topics: Basement Membrane; Carcinoma, Squamous Cell; Chemotaxis; Collagen; Collagenases; Dose-Response Relat | 1997 |
Thymidine phosphorylase activity in human bladder cancer: difference between superficial and invasive cancer.
Topics: Epithelial Cells; Floxuridine; Fluorouracil; Humans; Kinetics; Neoplasm Invasiveness; Neoplasm Stagi | 1997 |
Effects of sex steroids and growth factors on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in ovarian adenocarcinoma OMC-3 cells.
Topics: Basement Membrane; Cell Division; Cell Movement; Collagenases; Culture Media, Conditioned; Cystadeno | 1998 |
[Case report of a patient with invading bladder cancer and lymph node swelling which decreased following 5'-DFUR treatment].
Topics: Aged; Antineoplastic Agents; Child, Preschool; Floxuridine; Humans; Lymph Nodes; Lymphatic Metastasi | 2000 |
Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.
Topics: Affinity Labels; Animals; Antibodies, Monoclonal; Antibody Formation; Antimetabolites, Antineoplasti | 2002 |