floxuridine has been researched along with Herpes Simplex in 6 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-(2-Fluoroethyl)-2'-deoxyuridine (FEDU), its 2'-fluoroarabinofuranosyl analog (FEFAU) and the 2'-fluoroarabinofuranosyl analog (CEFAU) of the potent anti-herpesvirus compound 5-(2-chloroethyl)-2'-deoxyuridine (CEDU) were evaluated for activity against herpes simplex virus type 1 (HSV-1) and HSV-2 in vitro and in vivo." | 3.67 | In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil. ( De Clercq, E; Griengl, H; Rosenwirth, B; Schwarz, W; Streicher, W; Wanek, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YC | 1 |
| Nakayama, K | 1 |
| Grill, SP | 1 |
| Rosenwirth, B | 1 |
| Streicher, W | 1 |
| De Clercq, E | 1 |
| Wanek, E | 1 |
| Schwarz, W | 1 |
| Griengl, H | 1 |
| Iwashina, T | 1 |
| Tovell, DR | 1 |
| Xu, L | 1 |
| Tyrrell, DL | 1 |
| Knaus, EE | 1 |
| Wiebe, LI | 1 |
| Schneweis, KE | 1 |
| Hanna, C | 1 |
| Gologan, R | 1 |
1 review available for floxuridine and Herpes Simplex
| Article | Year |
|---|---|
[Aspects of antiviral therapy in herpes infections].
Topics: Animals; Antiviral Agents; Azauridine; Cytarabine; Encephalitis; Floxuridine; Herpes Simplex; Herpes | 1972 |
5 other studies available for floxuridine and Herpes Simplex
| Article | Year |
|---|---|
Roles of thymidylate synthetase activity in herpes simplex virus-infected HeLa cells.
Topics: Drug Synergism; Floxuridine; HeLa Cells; Herpes Simplex; Humans; Methyltransferases; Nucleosides; Th | 1983 |
In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Chemical Phe | 1987 |
Synthesis and antiviral activity of IVFRU, a potential probe for the non-invasive diagnosis of herpes simplex encephalitis.
Topics: Animals; Antiviral Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Dogs; Encephalitis; Eryth | 1988 |
[Immunologic analysis of the two Herpes simplex type viruses].
Topics: Animals; Antibodies, Viral; Antibody Specificity; Antigens, Viral; Bromodeoxyuridine; Cross Reaction | 1972 |
Incorporation of idoxuridine analogs into corneal herpes simplex virus.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cornea; DNA, Viral; Epithelium; Floxuridine; Fluorourac | 1972 |