floxuridine has been researched along with Deficiency, Mental in 8 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The main clinical features are mental retardation, typical facial dysmorphism and macroorchidism." | 2.37 | [Mental retardation linked to fragility of chromosome X: current knowledge]. ( Auger, M; Giraud, F; Mattei, JF; Mattei, MG, 1984) |
| " Fibroblast cultures from 10 retarded males expressed fra(X) in a dose-response relationship to increasing concentrations of FUdR." | 1.27 | Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28. Results of folic acid treatment on fra(X) expression. ( Nielsen, KB; Tommerup, N, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hecht, F | 1 |
| Jacky, PB | 1 |
| Sutherland, GR | 1 |
| Jacobs, PA | 1 |
| Hunt, PA | 1 |
| Mayer, M | 1 |
| Wang, JC | 1 |
| Boss, GR | 1 |
| Erbe, RW | 1 |
| Nielsen, KB | 1 |
| Tommerup, N | 3 |
| Mattei, JF | 1 |
| Mattei, MG | 1 |
| Auger, M | 1 |
| Giraud, F | 1 |
| Glover, TW | 1 |
| Nielssen, KB | 1 |
| Mikkelsen, M | 1 |
| Poulsen, H | 1 |
| Brøndum-Nielsen, K | 1 |
| von Koskull, H | 1 |
| Aula, P | 1 |
| Ammälä, P | 1 |
| Nordström, AM | 1 |
| Rapola, J | 1 |
2 reviews available for floxuridine and Deficiency, Mental
| Article | Year |
|---|---|
The fragile X chromosome: current methods.
Topics: Cells, Cultured; Chromosome Fragility; Chromosome Mapping; Female; Fibroblasts; Floxuridine; Folic A | 1982 |
[Mental retardation linked to fragility of chromosome X: current knowledge].
Topics: Bromodeoxyuridine; Child; Chromosome Banding; Ear, External; Face; Floxuridine; Folic Acid; Fragile | 1984 |
6 other studies available for floxuridine and Deficiency, Mental
| Article | Year |
|---|---|
Expression of the marker (X) (q28) in lymphoblastoid cell lines.
Topics: Cell Line; Culture Media; Female; Floxuridine; Gene Expression Regulation; Genetic Linkage; Genetic | 1982 |
Cytogenetic investigations in mentally retarded and normal males from 14 families with the fragile site at Xq28. Results of folic acid treatment on fra(X) expression.
Topics: Adolescent; Adult; Bromodeoxyuridine; Cells, Cultured; Child; Child, Preschool; Chromosome Fragile S | 1984 |
FUdR induction of the X chromosome fragile site: evidence for the mechanism of folic acid and thymidine inhibition.
Topics: Cells, Cultured; DNA; Female; Floxuridine; Folic Acid; Humans; Intellectual Disability; Lymphocytes; | 1981 |
Marker X chromosome induction in fibroblasts by FUdR.
Topics: Adult; Cells, Cultured; Chromosome Fragility; Female; Floxuridine; Humans; Intellectual Disability; | 1981 |
5-Fluoro-2'-deoxyuridine induction of the fragile site on Xq28 associated with X linked mental retardation.
Topics: Cells, Cultured; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Female; Floxuri | 1981 |
Improved technique for the expression of fragile-X in cultured amniotic fluid cells.
Topics: Adult; Amniotic Fluid; Cells, Cultured; Chromosome Fragility; Diazepam; Female; Floxuridine; Humans; | 1985 |