Page last updated: 2024-11-06

floxuridine and Cytomegalovirus

floxuridine has been researched along with Cytomegalovirus in 8 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.

Research Excerpts

ExcerptRelevanceReference
"Human cytomegalovirus was capable of adsorbing to and penetrating guinea pig cells, but was unable to replicate new virus."1.25Nonproductive infection of guinea pig cells with human cytomegalovirus. ( Fioretti, A; Furukawa, T; Plotkin, SA; Santoli, D, 1973)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Raić-Malić, S1
Svedruzić, D1
Gazivoda, T1
Marunović, A1
Hergold-Brundić, A1
Nagl, A1
Balzarini, J1
De Clercq, E1
Mintas, M1
PLOWRIGHT, W1
MACADAM, RF1
ARMSTRONG, JA1
Chua, CC1
Carter, TH1
St Jeor, S1
Sachs, MS1
Selker, EU1
Lin, B1
Roberts, CJ1
Luo, Z1
Vaught-Alexander, D1
Margolin, BS1
Tyms, AS1
Davis, JM1
Clarke, JR1
Jeffries, DJ1
Feigin, RD1
Shackelford, PG1
Haymond, MW1
DeVivo, DC1
Furukawa, T2
Fioretti, A2
Plotkin, S1
Santoli, D1
Plotkin, SA1

Other Studies

8 other studies available for floxuridine and Cytomegalovirus

ArticleYear
Synthesis and antitumor activities of novel pyrimidine derivatives of 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid and 4,5-didehydro-5,6- dideoxy-L-ascorbic acid.
    Journal of medicinal chemistry, 2000, Dec-14, Volume: 43, Issue:25

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Ascorbic Acid; Cell Line; Crystallography, X-Ray;

2000
GROWTH AND CHARACTERIZATION OF THE VIRUS OF BOVINE MALIGNANT CATARRHAL FEVER IN EAST AFRICA.
    Journal of general microbiology, 1965, Volume: 39

    Topics: Africa, Eastern; Animals; Cattle; Cattle Diseases; Chloroform; Cytomegalovirus; Cytopathogenic Effec

1965
Transcription of the human cytomegalovirus genome in productively infected cells.
    The Journal of general virology, 1981, Volume: 56, Issue:Pt 1

    Topics: Cells, Cultured; Cycloheximide; Cytomegalovirus; DNA, Viral; Floxuridine; Genes, Viral; Humans; Lung

1981
Expression of herpes virus thymidine kinase in Neurospora crassa.
    Nucleic acids research, 1997, Jun-15, Volume: 25, Issue:12

    Topics: Antiviral Agents; Bromodeoxyuridine; Cloning, Molecular; Cytomegalovirus; DNA Replication; Floxuridi

1997
Synthesis of cytomegalovirus DNA is an antiviral target late in virus growth.
    The Journal of general virology, 1987, Volume: 68 ( Pt 6)

    Topics: Acyclovir; Antiviral Agents; Cell Line; Cytomegalovirus; DNA, Viral; Floxuridine; Foscarnet; Gancicl

1987
Floxuridine treatment of congenital cytomegalic inclusion disease.
    Pediatrics, 1971, Volume: 48, Issue:2

    Topics: Blood; Cerebrospinal Fluid; Cytomegalovirus; Cytomegalovirus Infections; Floxuridine; Humans; Infant

1971
Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication.
    Journal of virology, 1973, Volume: 11, Issue:6

    Topics: Amino Acids; Antigens, Viral; Bromodeoxyuridine; Carbon Isotopes; Cell Line; Centrifugation, Density

1973
Nonproductive infection of guinea pig cells with human cytomegalovirus.
    Journal of virology, 1973, Volume: 11, Issue:6

    Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Nucleus; Complement Fixation Tests; Cyc

1973