floxuridine has been researched along with Cleft Palate in 7 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Cleft Palate: Congenital fissure of the soft and/or hard palate, due to faulty fusion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cleft palate was induced in rat foetuses using 5-fluoro-2-desoxyuridine and was associated with greatly decreased mucopolysaccharide synthesis." | 1.26 | Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate. ( Ferguson, MW, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferguson, MW | 3 |
| Singh, GD | 2 |
| Moxham, BJ | 2 |
| Langley, MS | 1 |
| Embery, G | 1 |
| Bro-Rasmussen, F | 1 |
| Jensen, B | 1 |
| Hansen, OM | 1 |
| Ostergaard, AH | 1 |
| Williams, JP | 1 |
7 other studies available for floxuridine and Cleft Palate
| Article | Year |
|---|---|
Developmental mechanisms in normal and abnormal palate formation with particular reference to the aetiology, pathogenesis and prevention of cleft palate.
Topics: Alligators and Crocodiles; Animals; Cleft Palate; Disease Models, Animal; Female; Floxuridine; Micro | 1981 |
Mesenchymal cell activity during 5-fluoro-2-deoxyuridine-induced cleft palate formation in the rat.
Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Cell Division; Cleft Palate; Embryon | 1996 |
Glycosaminoglycan biosynthesis during 5-fluoro-2-deoxyuridine-induced palatal clefts in the rat.
Topics: Animals; Chondroitin Sulfates; Cleft Palate; Densitometry; Dermatan Sulfate; Electrophoresis, Cellul | 1997 |
The mechanism of palatal shelf elevation and the pathogenesis of cleft palate.
Topics: Animals; Cleft Palate; Female; Floxuridine; Glycosaminoglycans; Palate; Rats; Rats, Inbred Strains | 1977 |
The teratogenic effects of 5-fluoro-2-desoxyuridine (F.U.D.R.) on the Wistar rat fetus with particular reference to cleft palate.
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Central Nervous System; Cleft Palate; Fetus; Flox | 1978 |
Fluorodeoxyuridine-induced malformations in mice. Studies on the early stages of teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cleft Palate; Clubfoot; Encephalocele; Femal | 1971 |
Incorporation of thymidine after administration of fluorouracil and fluorouridine to adult and embryo mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, Drug; E | 1971 |