floxuridine has been researched along with Cell Transformation, Neoplastic in 40 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Puromycin was used to study the effect of the inhibition of protein synthesis on transformation of hamster cells (BHK21) by polyoma virus." | 1.25 | Effect of the inhibition of protein synthesis on the establishment of transformation by polyoma virus. ( Basilico, C; Marin, G, 1967) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (92.50) | 18.7374 |
| 1990's | 3 (7.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawamura, H | 1 |
| Hashimoto, Y | 1 |
| Jones, PA | 2 |
| Benedict, WF | 2 |
| Baker, MS | 1 |
| Mondal, S | 1 |
| Rapp, U | 1 |
| Heidelberger, C | 3 |
| Beard, P | 1 |
| Acheson, NH | 1 |
| Maxwell, IH | 1 |
| Hirai, K | 1 |
| Defendi, V | 1 |
| Smith, CA | 1 |
| Hanawalt, PC | 1 |
| Rosenthal, LJ | 1 |
| Nomura, S | 4 |
| Fischinger, PJ | 4 |
| Türler, H | 2 |
| Salomon, C | 1 |
| Weil, R | 2 |
| Manor, H | 1 |
| Kamen, R | 1 |
| Geng, Y | 1 |
| Gheuens, E | 1 |
| de Bruijn, EA | 1 |
| Fogt, F | 1 |
| Wan, J | 1 |
| O'Hara, C | 1 |
| Bistrian, BR | 1 |
| Blackburn, GL | 1 |
| Istfan, NW | 1 |
| Kidson, SH | 1 |
| De Haan, JB | 1 |
| Berjis, M | 1 |
| Green, MH | 1 |
| Saneyoshi, M | 1 |
| Peterson, AR | 1 |
| Mattern, CF | 2 |
| Gerwin, BI | 1 |
| Dunn, KJ | 3 |
| Hartley, JW | 1 |
| Kern, J | 1 |
| Gilden, RV | 1 |
| Huebner, RJ | 1 |
| Bello, LJ | 1 |
| Ginsberg, HS | 1 |
| Taderera, JV | 1 |
| Hawtrey, AO | 1 |
| Borek, E | 1 |
| Ryan, A | 1 |
| Barbanti-Brodano, G | 1 |
| Fiume, L | 1 |
| Pollack, RE | 1 |
| Green, H | 1 |
| Todaro, GJ | 1 |
| Zur Hausen, H | 1 |
| Hancock, R | 1 |
| Marin, G | 1 |
| Basilico, C | 1 |
| Culp, LA | 2 |
| Grimes, WJ | 1 |
| Black, PH | 2 |
| Mora, PT | 1 |
| Cumar, FA | 1 |
| Brady, RO | 1 |
| Nesnow, S | 1 |
| Mian, AM | 1 |
| Oki, T | 1 |
| Dexter, DL | 1 |
| Fogel, M | 1 |
| Poste, G | 1 |
| Ossowski, L | 1 |
| Reich, E | 1 |
| Smith, GL | 1 |
| Consigli, RA | 1 |
| Vogel, A | 2 |
| Risser, R | 1 |
| Pollack, R | 1 |
| Coscia, JF | 1 |
| Hare, JD | 1 |
| Ensminger, WD | 1 |
| Tamm, I | 1 |
| Ozanne, B | 1 |
3 reviews available for floxuridine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deo | 1985 |
Lysogenic induction.
Topics: Animals; Bacteria; Bacteriolysis; Bacteriophages; Cell Transformation, Neoplastic; Chromosomes; Coli | 1973 |
Cellular DNA replication in viral infection.
Topics: Adenoviridae; Animals; Autoradiography; Cell Transformation, Neoplastic; Cycloheximide; Cytoplasm; D | 1971 |
37 other studies available for floxuridine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Inhibitory effect of 5-halogenated deoxyuridines on in vitro keratinization of a transformed rat urinary bladder epithelial cell line.
Topics: Animals; Binding, Competitive; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; DNA Re | 1981 |
Oncogenic transformation of C3H/10T1/2 clone 8 mouse embryo cells by halogenated pyrimidine nucleosides.
Topics: Animals; Antigens, Viral; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transformation, Neoplast | 1976 |
Strand-specific transcription of polyoma virus DNA-early in productive infection and in transformed cells.
Topics: Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Culture Techniques; Cytoplasm; DNA, Viral; | 1975 |
The effects of serum concentration on the level of integration of simian virus (SV40) genome and the transformation frequency in SV40-infected Chinese hamster cells.
Topics: Antigens, Viral; Blood; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Colchicine; C | 1976 |
Repair replication in human cells. Simplified determination utilizing hydroxyurea.
Topics: Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; DNA | 1976 |
Isolation and characterization of poly(A)-containing polyoma "early" and "late" messenger RNAs.
Topics: Cell Line; Cell Transformation, Neoplastic; DNA Replication; Floxuridine; Nucleic Acid Hybridization | 1976 |
Rapid screening assay for revertants of murine sarcoma virus-transformed cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Clone Cells; Floxuridine; Gammaretrovirus; Leukemia Viru | 1976 |
Interaction of polyoma and mouse DNAs. IV. Time course and extent of integration of polyoma DNA into mouse DNA during lytic infection.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; DNA; DNA, Neoplasm; DNA, Vir | 1977 |
Polyoma-induced stimulation of cellular RNA synthesis is paralleled by changed expression of the viral genome.
Topics: Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cycloheximide; Floxuridine; Genes; Kinetic | 1977 |
Polyoma virus-specific RNA synthesis in an inducible line of polyoma virus-transformed rat cells.
Topics: Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytop | 1978 |
Activation and cytotoxicity of 5'-deoxy-5-fluorouridine in c-H-ras transformed NIH 3T3 cells.
Topics: Animals; Biotransformation; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationsh | 1991 |
Flow cytometric measurement of cell cycle kinetics in rat Walker-256 carcinoma following in vivo and in vitro pulse labelling with bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Carcinoma 256, Walker; Cell Cycle; Cell Line; Cell Transformation, Neopl | 1991 |
Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells.
Topics: Animals; Bromodeoxyuridine; Catechol Oxidase; Cell Line; Cell Transformation, Neoplastic; Floxuridin | 1990 |
Selective cytotoxicity of L-canavanine in tumorigenic Madin-Darby canine kidney T1 cells.
Topics: Animals; Canavanine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cycloheximide; Dogs; | 1986 |
[Recent advances and trends in cancer chemotherapy using nucleoside analogs].
Topics: Animals; Cell Transformation, Neoplastic; Cytarabine; Floxuridine; Humans; Neoplasms; Nucleosides; S | 1988 |
Revertants of mouse cells transformed by murine sarcoma virus. II. Flat variants induced by fluordeoxyuridine and colcemid.
Topics: Agglutination Tests; Animals; Antigens, Viral; Cell Fusion; Cell Line; Cell Transformation, Neoplast | 1973 |
Revertants of mouse cells transformed by murine sarcoma virus: flat variants without a rescuable sarcoma virus from a clone of BALB/3T3 transformed by Kirsten MSV.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Colchicine; Conca | 1974 |
T antigens of bovine and canine adenoviruses demonstrated by immunofluorescence.
Topics: Adenoviridae; Animals; Antigens; Cattle; Cell Transformation, Neoplastic; Complement Fixation Tests; | 1969 |
Inhibition of host protein synthesis in type 5 adenovirus-infected cells.
Topics: Acid Phosphatase; Adenoviridae; Antigens; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Com | 1967 |
Transformation of hamster cells in vitro by 1- -D arabinofuranosylcytosine, 5-fluorodeoxyuridine and hydroxyurea.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Cytarabine; Cytosine Nucle | 1972 |
In vitro effect of a 5-fluorodeoxyuridine albumin conjugate on tumour cells and on peritoneal macrophages.
Topics: Animals; Carbodiimides; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; | 1974 |
Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability.
Topics: Animals; Cell Transformation, Neoplastic; Clone Cells; Contact Inhibition; Cricetinae; Floxuridine; | 1968 |
Persistence of the viral genome in adenovirus type 12-infected hamster cells.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antigens; Autoradiography; Cell Transformation, Neop | 1968 |
The use of polyoma virus for studies on genetic regulation in mammalian cells.
Topics: Animals; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Culture Techniques; Cyto | 1970 |
Effect of the inhibition of protein synthesis on the establishment of transformation by polyoma virus.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Cricetinae; D | 1967 |
Contact-inhibited revertant cell lines isolated from SV40-transformed cells. I. Biologic, virologic, and chemical properties.
Topics: Animals; Antigens, Viral; Cell Fusion; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Clo | 1971 |
A common biochemical change in SV40 and polyoma virus transformed mouse cells coupled to control of cell growth in culture.
Topics: Animals; Carbon Isotopes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chromatograph | 1971 |
Contact-inhibited revertant cell lines isolated from simian virus 40-transformed cells. 3. Concanavalin A-selected revertant cells.
Topics: Agglutination; Animals; Antigens, Viral; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Ch | 1972 |
Fluorinated pyrimidines. 41. Syntheses of 5-trifluoromethyl-3'-deoxyuridine and 5-fluoro-3'-deoxyuridine.
Topics: Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, Ion Exc | 1972 |
Induction of virus synthesis in polyoma-transformed cells by DNA antimetabolites and by irradiation after pretreatment with 5-bromodeoxyuridine.
Topics: Animals; Antigens, Viral; Antimetabolites; Bromodeoxyuridine; Cell Division; Cell Line; Cell Transfo | 1972 |
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transfor | 1972 |
Effects of nucleoside analogs on transcription of simian virus 40.
Topics: Animals; Bromine; Cell Line; Cell Transformation, Neoplastic; DNA, Viral; Fibroblasts; Floxuridine; | 1972 |
Transient inhibition of polyoma virus synthesis by sendai virus (parainfluenza I). II. Mechanism of the interference by inactivated virus.
Topics: Animals; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Culture Techniques; Dact | 1972 |
Isolation and characterization of revertant cell lines. 3. Isolation of density-revertants of SV40-transformed 3T3 cells using colchicine.
Topics: Animals; Antigens, Neoplasm; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplasti | 1973 |
A polyoma-induced hamster tumor cell with altered DNA synthesis in vivo and reduced polynucleotide ligase activity in vitro.
Topics: Animals; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Cell Transformation, Neo | 1973 |
Rapid screening assay for revertants derived from MSV-transformed cells.
Topics: Animals; Cell Count; Cell Transformation, Neoplastic; Clone Cells; Cytological Techniques; Floxuridi | 1973 |
Selection of revertants of Kirsten sarcoma virus transformed nonproducer BALB-3T3 cells.
Topics: Animals; Autoradiography; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; Concanavali | 1974 |