floxuridine has been researched along with Carcinoma in 54 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied three new dose schedules of hepatic arterial infusion of floxuridine (FUDR) and leucovorin and update survival analysis of a previously reported trial using these drugs by hepatic arterial infusion for patients with hepatic metastases from colorectal carcinoma." | 9.07 | Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update. ( Bertino, JR; Botet, J; Budd, AJ; Chapman, D; Cohen, A; Conti, JA; Kemeny, N; Mazumdar, M; Seiter, K; Sigurdson, ER, 1994) |
| "A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)." | 7.70 | [A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000) |
| "Parameters for inhibition of thymidylate synthase (TS) in a DMH-induced transplantable rat colon carcinoma were studied after intraperitoneal administration of bolus doxifluridine (5'-dFUR) 200 mg/kg." | 7.67 | Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. ( Almersjö, O; Berne, M; Gustavsson, B; Spears, P; Sundström, E, 1988) |
| " The neurotoxicity was dose related, affecting 7 of 8 patients in the high dosage group and 3 of 9 patients in the low dosage group." | 6.66 | Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd). ( Fosså, SD; Heier, MS, 1986) |
| "Concurrent carboplatin chemotherapy did not significantly improve the long-term survival after inductive carboplatin and floxuridine chemotherapy in locoregionally advanced nasopharyngeal carcinoma." | 5.20 | Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area. ( Cao, KJ; Guo, L; Guo, X; Hong, MH; Huang, PY; Mai, HQ; Mo, HY; Qian, CN; Wu, PH; Zeng, Q, 2015) |
| "The combination of irinotecan and a fluoropyrimidine has been widely accepted as a treatment for advanced colorectal carcinoma." | 5.11 | Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy. ( Hiro, J; Inoue, Y; Kobayashi, M; Kusunoki, M; Miki, C; Mori, K; Shirane, M; Tanaka, K; Yanagi, H, 2004) |
| "We studied three new dose schedules of hepatic arterial infusion of floxuridine (FUDR) and leucovorin and update survival analysis of a previously reported trial using these drugs by hepatic arterial infusion for patients with hepatic metastases from colorectal carcinoma." | 5.07 | Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update. ( Bertino, JR; Botet, J; Budd, AJ; Chapman, D; Cohen, A; Conti, JA; Kemeny, N; Mazumdar, M; Seiter, K; Sigurdson, ER, 1994) |
| " Our study population was patients who had undergone arterial mapping in preparation for placement of a hepatic arterial floxuridine infusion pump for treatment of metastatic hepatic colorectal carcinoma." | 3.72 | Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump. ( Brancatelli, G; Federle, MP; Geller, DA; Kapoor, V; Katyal, S; Marsh, JW, 2003) |
| " Using a murine dorsal air sac (DAS) assay, we have previously shown that UFT and its metabolites, gamma-hydroxybutyric acid (GHB) and 5-fluorouracil (5-FU), inhibited the angiogenesis induced by murine renal cell carcinoma." | 3.71 | gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. ( Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K, 2001) |
| "A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)." | 3.70 | [A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000) |
| " One patient had severe ileitis caused by intravenous administration of 5-fluorouracil; the other had severe duodenitis caused by infusion of 5-floxuridine into the hepatic artery by an implanted pump." | 3.68 | Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings. ( Hiehle, JF; Levine, MS, 1991) |
| "Four human head and neck xenograft (HNX) tumour lines grown in nude mice and two murine colon carcinomas (Colon 26 and 38) were tested for their sensitivity to 5-fluorouracil (5-FU) and its prodrug 5'deoxy-5-fluorouridine (Doxifluridine, 5'd-FUR)." | 3.67 | Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes. ( Braakhuis, BJ; de Bruijn, EA; Laurensse, EJ; Peters, GJ; Pinedo, HM; van Walsum, M, 1989) |
| "Parameters for inhibition of thymidylate synthase (TS) in a DMH-induced transplantable rat colon carcinoma were studied after intraperitoneal administration of bolus doxifluridine (5'-dFUR) 200 mg/kg." | 3.67 | Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. ( Almersjö, O; Berne, M; Gustavsson, B; Spears, P; Sundström, E, 1988) |
| " The neurotoxicity was dose related, affecting 7 of 8 patients in the high dosage group and 3 of 9 patients in the low dosage group." | 2.66 | Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd). ( Fosså, SD; Heier, MS, 1986) |
| " Such simultaneous administration enabled us to substantially increase the dosage intensity of both, thereby increasing the effectiveness of each drug." | 2.40 | Infusional chemotherapy combined with recombinant human granulocyte colony stimulating factor: advantages and limitations. ( Lackman, RD; Weiss, AJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (66.67) | 18.7374 |
| 1990's | 7 (12.96) | 18.2507 |
| 2000's | 9 (16.67) | 29.6817 |
| 2010's | 2 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, PY | 1 |
| Zeng, Q | 1 |
| Cao, KJ | 1 |
| Guo, X | 1 |
| Guo, L | 1 |
| Mo, HY | 1 |
| Wu, PH | 1 |
| Qian, CN | 1 |
| Mai, HQ | 1 |
| Hong, MH | 1 |
| Chen, LC | 2 |
| Hsueh, C | 1 |
| Tsang, NM | 2 |
| Liang, Y | 2 |
| Chang, KP | 1 |
| Hao, SP | 1 |
| Yu, JS | 1 |
| Chang, YS | 2 |
| Martínez C, J | 1 |
| Jarufe C, N | 1 |
| González D, R | 1 |
| Alvarez Z, M | 1 |
| Chen, CC | 1 |
| Kapoor, V | 1 |
| Brancatelli, G | 1 |
| Federle, MP | 1 |
| Katyal, S | 1 |
| Marsh, JW | 1 |
| Geller, DA | 1 |
| WOLBERG, WH | 1 |
| JOHNSON, RO | 1 |
| CURRERI, AR | 1 |
| LINDNER, A | 1 |
| KUTKAM, T | 1 |
| SANKARANARAYANAN, K | 1 |
| RUCKER, R | 1 |
| ARRADONDO, J | 1 |
| OETTGEN, HF | 1 |
| CLIFFORD, P | 1 |
| CANDLER, P | 1 |
| SULLIVAN, RD | 1 |
| WATKINS, E | 1 |
| HEIDELBERGER, C | 2 |
| BOOHAR, J | 1 |
| BIRNIE, GD | 1 |
| REYES, P | 1 |
| Inoue, Y | 1 |
| Shirane, M | 1 |
| Miki, C | 1 |
| Hiro, J | 1 |
| Tanaka, K | 1 |
| Kobayashi, M | 1 |
| Mori, K | 1 |
| Yanagi, H | 1 |
| Kusunoki, M | 1 |
| Creaven, PJ | 1 |
| Madajewicz, S | 1 |
| Mittelman, A | 1 |
| Fujita, F | 1 |
| Fujita, M | 1 |
| Taguchi, T | 1 |
| Spagliardi, E | 1 |
| Torelli, P | 1 |
| Barra, M | 1 |
| Orsi, D | 1 |
| Bruzzo, F | 1 |
| van der Heyden, S | 1 |
| Gheuens, E | 1 |
| van de Vrie, W | 1 |
| Van Bockstaele, D | 1 |
| Van Oosterom, A | 1 |
| Eggermont, A | 1 |
| De Bruijn, EA | 2 |
| Castoldi, MC | 1 |
| Dellafiore, L | 1 |
| Pancera, G | 1 |
| Kemeny, N | 2 |
| Seiter, K | 1 |
| Conti, JA | 1 |
| Cohen, A | 1 |
| Bertino, JR | 1 |
| Sigurdson, ER | 1 |
| Botet, J | 1 |
| Chapman, D | 1 |
| Mazumdar, M | 1 |
| Budd, AJ | 1 |
| Weiss, AJ | 1 |
| Lackman, RD | 1 |
| Evrard, A | 1 |
| Cuq, P | 1 |
| Robert, B | 1 |
| Vian, L | 1 |
| Pèlegrin, A | 1 |
| Cano, JP | 1 |
| Leder, GH | 1 |
| Pillasch, J | 1 |
| Kornmann, M | 1 |
| Danenberg, PV | 1 |
| Link, KH | 1 |
| Hara, Y | 1 |
| Kawasaki, T | 1 |
| Yabata, E | 1 |
| Gen, T | 1 |
| Jibiki, M | 1 |
| Kudoh, A | 1 |
| Noguchi, N | 1 |
| Igarashi, K | 2 |
| Kikuchi, M | 1 |
| Gonen, M | 1 |
| Sullivan, D | 1 |
| Schwartz, L | 1 |
| Benedetti, F | 1 |
| Saltz, L | 1 |
| Stockman, J | 1 |
| Fong, Y | 1 |
| Jarnagin, W | 1 |
| Bertino, J | 1 |
| Tong, W | 1 |
| Paty, P | 1 |
| Basaki, Y | 1 |
| Chikahisa, L | 1 |
| Aoyagi, K | 1 |
| Miyadera, K | 1 |
| Yonekura, K | 1 |
| Hashimoto, A | 1 |
| Okabe, S | 1 |
| Wierzba, K | 1 |
| Yamada, Y | 1 |
| Gruenberger, T | 1 |
| Zhao, J | 1 |
| King, J | 1 |
| Chung, T | 1 |
| Clingan, PR | 1 |
| Morris, DL | 1 |
| Brockman, RW | 1 |
| Shaddix, SC | 1 |
| Rose, LM | 1 |
| Patt, YZ | 1 |
| Wallace, S | 1 |
| Hersh, EM | 1 |
| Hall, SW | 1 |
| Menachem, YB | 1 |
| Granmayeh, M | 1 |
| McBride, CM | 1 |
| Benjamin, RS | 1 |
| Mavligit, GM | 1 |
| Hiehle, JF | 1 |
| Levine, MS | 1 |
| Nakagawa, Y | 1 |
| Peters, GJ | 2 |
| Braakhuis, BJ | 1 |
| Laurensse, EJ | 2 |
| van Walsum, M | 1 |
| Pinedo, HM | 2 |
| Donegan, WL | 1 |
| Simoni, G | 1 |
| Bignami, P | 1 |
| Civalleri, D | 1 |
| Cosimelli, M | 1 |
| Craus, W | 1 |
| Percivale, PL | 1 |
| Repetto, M | 1 |
| Fujimoto, S | 1 |
| Shrestha, RD | 1 |
| Miyazaki, M | 1 |
| Endoh, F | 1 |
| Ohta, M | 1 |
| Togawa, Y | 1 |
| Okui, K | 1 |
| Heier, MS | 1 |
| Fosså, SD | 1 |
| van Dijk, J | 1 |
| van Groeningen, C | 1 |
| Leyva, A | 1 |
| Lankelma, J | 1 |
| Shepard, KV | 1 |
| Levin, B | 1 |
| Faintuch, J | 1 |
| Doria, MI | 1 |
| DuBrow, RA | 1 |
| Riddell, RH | 1 |
| Mercer, JR | 1 |
| Knaus, EE | 1 |
| Wiebe, LI | 1 |
| Valone, FH | 1 |
| Kohler, M | 1 |
| Fisher, K | 1 |
| Hannigan, J | 1 |
| Flam, M | 1 |
| Gandara, D | 1 |
| Hendrickson, C | 1 |
| Richman, E | 1 |
| Yu, KP | 1 |
| Berne, M | 1 |
| Gustavsson, B | 1 |
| Almersjö, O | 1 |
| Spears, P | 1 |
| Sundström, E | 1 |
| Park, JG | 1 |
| Collins, JM | 1 |
| Gazdar, AF | 1 |
| Allegra, CJ | 1 |
| Steinberg, SM | 1 |
| Greene, RF | 1 |
| Kramer, BS | 1 |
| Bello, LJ | 1 |
| Ginsberg, HS | 2 |
| Obert, G | 1 |
| Tripier, F | 1 |
| Bingen, A | 1 |
| Guir, J | 1 |
| Lawrence, WC | 1 |
| Coyle, M | 2 |
| McMahon, M | 2 |
| Strauss, B | 2 |
| Lucas, JJ | 1 |
| Kato, K | 1 |
| Dolyniuk, M | 1 |
| Wheeler, GP | 1 |
| Bowdon, BJ | 1 |
| Adamson, DJ | 1 |
| Vail, MH | 1 |
| Marcialis, MA | 1 |
| Biondi, E | 1 |
| Atzeni, A | 1 |
| Schivo, ML | 1 |
| Uccheddu, P | 1 |
| Loddo, B | 1 |
| Carter, BJ | 1 |
| Koczot, FJ | 1 |
| Garrison, J | 1 |
| Rose, JA | 1 |
| Dolin, R | 1 |
| Nakajima, S | 1 |
| Hamada, C | 1 |
| Uetake, H | 1 |
| Van Dyk, JJ | 1 |
| Clarkson, BD | 1 |
| Duschinsky, R | 1 |
| Keller, O | 1 |
| La Sala, E | 1 |
| Krakoff, IH | 1 |
| Rouse, HC | 1 |
| Schlesinger, RW | 1 |
| Poste, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter and Prospective Clinical Trial of Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma[NCT04522050] | Phase 1 | 65 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver[NCT00001576] | Phase 1 | 28 participants | Interventional | 1997-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for floxuridine and Carcinoma
| Article | Year |
|---|---|
[Current therapeutic options for liver metastasis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Catheter Ablation; Colorect | 2008 |
New potential treatment modalities for disseminated prostatic cancer.
Topics: Androgen Antagonists; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic A | 1984 |
Infusional chemotherapy combined with recombinant human granulocyte colony stimulating factor: advantages and limitations.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Doxorubicin; Dr | 1997 |
Radiation sensitizers.
Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs | 1976 |
6 trials available for floxuridine and Carcinoma
| Article | Year |
|---|---|
Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy, Ad | 2015 |
Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr | 2004 |
Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Drug A | 1994 |
Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Ca | 2001 |
Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd).
Topics: Adult; Aged; Brain Diseases; Carcinoid Tumor; Carcinoma; Cerebellar Diseases; Colonic Neoplasms; Ele | 1986 |
A Northern California Oncology Group randomized trial of leucovorin plus 5-fluorouracil versus sequential methotrexate, 5-fluorouracil, and leucovorin in patients with advanced colorectal cancer who failed treatment with 5-fluorouracil or 5-fluorodeoxyuri
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Drug Administration Sc | 1987 |
44 other studies available for floxuridine and Carcinoma
| Article | Year |
|---|---|
Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Pharmacological; Biomarkers, Tumor; Carcin | 2008 |
Epstein-Barr virus latent membrane protein 1 induces the chemotherapeutic target, thymidine phosphorylase, via NF-kappaB and p38 MAPK pathways.
Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Floxuridine; Humans; Nasopharyngeal Ne | 2010 |
Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump.
Topics: Aged; Angiography, Digital Subtraction; Antimetabolites, Antineoplastic; Carcinoma; Colorectal Neopl | 2003 |
Controlled-dose therapy as an adjunct to surgery.
Topics: Carcinoma; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Protein Deficiency | 1963 |
INHIBITION OF EHRLICH ASCITES TUMOR WITH 5-FLUOROURACIL AND OTHER AGENTS.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Floxuridine; Fluorouracil; Hydr | 1963 |
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona | 1963 |
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neop | 1964 |
FLUORINATED PYRIMIDINES. XXII. EFFECTS OF VARIOUS COMPOUNDS ON THE INCORPORATION OF (14C)FORMATE INTO DNA THYMINE IN SUSPENSIONS OF EHRLICH ASCITES CELLS.
Topics: Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; | 1964 |
FLUORINATED PYRIMIDINES. XXV. THE INHIBITION OF THYMIDYLATE SYNTHETASE FROM EHRLICH ASCITES CARCINOMA CELLS BY PYRIMIDINE ANALOGS.
Topics: Adenosine Triphosphate; Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Enzyme Inhibitors; Fl | 1965 |
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal | 1984 |
[The therapy of the liver metastases of colorectal carcinoma].
Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Combined Modality Therapy | 1994 |
5'-Deoxy-5-fluorouridine increases daunorubicin uptake in multidrug-resistant cells and its activity is related with P-gp 170 expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Carrier Proteins; Colon | 1994 |
[The evolution of the liver metastases from colorectal carcinoma treated with hepatic intra-arterial chemotherapy. The echographic and CT aspects].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Floxuridine; Fluoro | 1994 |
Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Colonic Neoplasms; Drug Synergism; Floxuridine; | 1999 |
Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 2000 |
[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; | 2000 |
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carc | 2001 |
Echogenicity of liver metastases from colorectal carcinoma is an independent prognostic factor in patients treated with regional chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Female; Flox | 2002 |
Biochemical aspects of chemotherapy of mouse colon carcinoma: fluoropyrimidines and pyrazofurin.
Topics: Amidophosphoribosyltransferase; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcino | 1977 |
Hepatic arterial infusion of Corynebacterium parvum and chemotherapy.
Topics: Antineoplastic Agents; Carcinoembryonic Antigen; Carcinoma; Catheterization; Female; Floxuridine; He | 1978 |
Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings.
Topics: Aged; Carcinoma; Duodenitis; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Ileitis; Inf | 1991 |
[Pharmacokinetics of anticancer drugs in hamsters with tongue carcinoma].
Topics: Animals; Bleomycin; Carcinoma; Cricetinae; Floxuridine; Kinetics; Male; Mesocricetus; Peplomycin; Ti | 1986 |
Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes.
Topics: Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Drug Resistance; Female; Floxuridine; | 1989 |
Hepatic artery infusion chemotherapy for colorectal metastases: a personal experience.
Topics: Adult; Aged; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans | 1985 |
[Comparison of the performance of a totally implantable pump and conventional access systems in regional arterial chemotherapy of liver tumors].
Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Floxuridine; Humans; Infusions, I | 1986 |
Combined therapy of polyamine antimetabolites and antitumor drugs for human gastric cancer xenotransplanted into nude mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcino | 1986 |
Toxicity and antitumor effect of 5-fluorouracil and its rescue by uridine.
Topics: Animals; Body Temperature Regulation; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug | 1986 |
Hepatitis in patients receiving intraarterial chemotherapy for metastatic colorectal carcinoma.
Topics: Bilirubin; Carcinoma; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Female; Floxuridine | 1987 |
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Erythro | 1987 |
Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat.
Topics: Animals; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Male | 1988 |
Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human colorectal carcinoma cell lines.
Topics: Carcinoma; Cell Survival; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; L | 1988 |
Inhibition of host protein synthesis in type 5 adenovirus-infected cells.
Topics: Acid Phosphatase; Adenoviridae; Antigens; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Com | 1967 |
[Effects of arginine deficiency on the replication of vaccinial virus].
Topics: Arginine; Carcinoma; Cell Line; DNA, Viral; Floxuridine; Humans; Microscopy, Electron; Mouth Neoplas | 1971 |
Evidence for a relationship between equine abortion (herpes) virus deoxyribonucleic acid synthesis and the S phase of the KB cell mitotic cycle.
Topics: Animals; Autoradiography; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; C | 1971 |
Failure of alkylated HEp.2 cells to replicate newly synthesized DNA.
Topics: Alkanes; Alkylating Agents; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; | 1971 |
Synthesis of virus-specific ribonucleic acid in KB cells infected with type 2 adenovirus.
Topics: Adenoviridae; Carcinoma; Cell Line; Cell-Free System; Cells, Cultured; Centrifugation, Density Gradi | 1971 |
DNA synthesis, repair and chromosome breaks in eucaryotic cells.
Topics: Alkylating Agents; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chroma | 1972 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Rep | 1972 |
5-Iodo-2-deoxyuridine resistance of vaccinia viruses in cells endowed with thymidine kinase activity.
Topics: Bromodeoxyuridine; Carcinoma; Cell Line; Drug Resistance, Microbial; Floxuridine; Humans; Idoxuridin | 1973 |
Separate helper functions provided by adenovirus for adenovirus-associated virus multiplication.
Topics: Adenoviridae; Carcinoma; Cell Line; DNA, Viral; Floxuridine; Helper Viruses; Humans; Kinetics; Mouth | 1973 |
Tumor-specific transplantation antigen activity of freshly adenovirus-infected cells. Intercurrent immunization against viral tumorigenesis with virus-infected cells.
Topics: Adenoviridae; Animals; Animals, Newborn; Antigens, Neoplasm; Carcinoma; Cell Line; Cricetinae; Floxu | 1974 |
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carci | 1967 |
The effects of arginine starvation on macromolecular synthesis in infection with type 2 adenovirus. I. Synthesis and utilization of structural proteins.
Topics: Adenoviridae; Adenoviridae Infections; Amino Acids; Arginine; Carbon Isotopes; Carcinoma; Cell Line; | 1972 |
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transfor | 1972 |