Page last updated: 2024-11-06

floxuridine and Carcinoma

floxuridine has been researched along with Carcinoma in 54 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"We studied three new dose schedules of hepatic arterial infusion of floxuridine (FUDR) and leucovorin and update survival analysis of a previously reported trial using these drugs by hepatic arterial infusion for patients with hepatic metastases from colorectal carcinoma."9.07Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update. ( Bertino, JR; Botet, J; Budd, AJ; Chapman, D; Cohen, A; Conti, JA; Kemeny, N; Mazumdar, M; Seiter, K; Sigurdson, ER, 1994)
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."7.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
"Parameters for inhibition of thymidylate synthase (TS) in a DMH-induced transplantable rat colon carcinoma were studied after intraperitoneal administration of bolus doxifluridine (5'-dFUR) 200 mg/kg."7.67Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. ( Almersjö, O; Berne, M; Gustavsson, B; Spears, P; Sundström, E, 1988)
" The neurotoxicity was dose related, affecting 7 of 8 patients in the high dosage group and 3 of 9 patients in the low dosage group."6.66Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd). ( Fosså, SD; Heier, MS, 1986)
"Concurrent carboplatin chemotherapy did not significantly improve the long-term survival after inductive carboplatin and floxuridine chemotherapy in locoregionally advanced nasopharyngeal carcinoma."5.20Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area. ( Cao, KJ; Guo, L; Guo, X; Hong, MH; Huang, PY; Mai, HQ; Mo, HY; Qian, CN; Wu, PH; Zeng, Q, 2015)
"The combination of irinotecan and a fluoropyrimidine has been widely accepted as a treatment for advanced colorectal carcinoma."5.11Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy. ( Hiro, J; Inoue, Y; Kobayashi, M; Kusunoki, M; Miki, C; Mori, K; Shirane, M; Tanaka, K; Yanagi, H, 2004)
"We studied three new dose schedules of hepatic arterial infusion of floxuridine (FUDR) and leucovorin and update survival analysis of a previously reported trial using these drugs by hepatic arterial infusion for patients with hepatic metastases from colorectal carcinoma."5.07Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update. ( Bertino, JR; Botet, J; Budd, AJ; Chapman, D; Cohen, A; Conti, JA; Kemeny, N; Mazumdar, M; Seiter, K; Sigurdson, ER, 1994)
" Our study population was patients who had undergone arterial mapping in preparation for placement of a hepatic arterial floxuridine infusion pump for treatment of metastatic hepatic colorectal carcinoma."3.72Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump. ( Brancatelli, G; Federle, MP; Geller, DA; Kapoor, V; Katyal, S; Marsh, JW, 2003)
" Using a murine dorsal air sac (DAS) assay, we have previously shown that UFT and its metabolites, gamma-hydroxybutyric acid (GHB) and 5-fluorouracil (5-FU), inhibited the angiogenesis induced by murine renal cell carcinoma."3.71gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. ( Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K, 2001)
"A left radical mastectomy was performed on a 53-year-old woman, diagnosed with left inflammatory breast cancer, after local arterial chemotherapy with cyclophosphamide (CPA), doxorubicin and 5-fluorouracil (5-FU)."3.70[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)]. ( Gen, T; Hara, Y; Igarashi, K; Jibiki, M; Kawasaki, T; Kikuchi, M; Kudoh, A; Noguchi, N; Yabata, E, 2000)
" One patient had severe ileitis caused by intravenous administration of 5-fluorouracil; the other had severe duodenitis caused by infusion of 5-floxuridine into the hepatic artery by an implanted pump."3.68Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings. ( Hiehle, JF; Levine, MS, 1991)
"Four human head and neck xenograft (HNX) tumour lines grown in nude mice and two murine colon carcinomas (Colon 26 and 38) were tested for their sensitivity to 5-fluorouracil (5-FU) and its prodrug 5'deoxy-5-fluorouridine (Doxifluridine, 5'd-FUR)."3.67Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes. ( Braakhuis, BJ; de Bruijn, EA; Laurensse, EJ; Peters, GJ; Pinedo, HM; van Walsum, M, 1989)
"Parameters for inhibition of thymidylate synthase (TS) in a DMH-induced transplantable rat colon carcinoma were studied after intraperitoneal administration of bolus doxifluridine (5'-dFUR) 200 mg/kg."3.67Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat. ( Almersjö, O; Berne, M; Gustavsson, B; Spears, P; Sundström, E, 1988)
" The neurotoxicity was dose related, affecting 7 of 8 patients in the high dosage group and 3 of 9 patients in the low dosage group."2.66Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd). ( Fosså, SD; Heier, MS, 1986)
" Such simultaneous administration enabled us to substantially increase the dosage intensity of both, thereby increasing the effectiveness of each drug."2.40Infusional chemotherapy combined with recombinant human granulocyte colony stimulating factor: advantages and limitations. ( Lackman, RD; Weiss, AJ, 1997)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199036 (66.67)18.7374
1990's7 (12.96)18.2507
2000's9 (16.67)29.6817
2010's2 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, PY1
Zeng, Q1
Cao, KJ1
Guo, X1
Guo, L1
Mo, HY1
Wu, PH1
Qian, CN1
Mai, HQ1
Hong, MH1
Chen, LC2
Hsueh, C1
Tsang, NM2
Liang, Y2
Chang, KP1
Hao, SP1
Yu, JS1
Chang, YS2
Martínez C, J1
Jarufe C, N1
González D, R1
Alvarez Z, M1
Chen, CC1
Kapoor, V1
Brancatelli, G1
Federle, MP1
Katyal, S1
Marsh, JW1
Geller, DA1
WOLBERG, WH1
JOHNSON, RO1
CURRERI, AR1
LINDNER, A1
KUTKAM, T1
SANKARANARAYANAN, K1
RUCKER, R1
ARRADONDO, J1
OETTGEN, HF1
CLIFFORD, P1
CANDLER, P1
SULLIVAN, RD1
WATKINS, E1
HEIDELBERGER, C2
BOOHAR, J1
BIRNIE, GD1
REYES, P1
Inoue, Y1
Shirane, M1
Miki, C1
Hiro, J1
Tanaka, K1
Kobayashi, M1
Mori, K1
Yanagi, H1
Kusunoki, M1
Creaven, PJ1
Madajewicz, S1
Mittelman, A1
Fujita, F1
Fujita, M1
Taguchi, T1
Spagliardi, E1
Torelli, P1
Barra, M1
Orsi, D1
Bruzzo, F1
van der Heyden, S1
Gheuens, E1
van de Vrie, W1
Van Bockstaele, D1
Van Oosterom, A1
Eggermont, A1
De Bruijn, EA2
Castoldi, MC1
Dellafiore, L1
Pancera, G1
Kemeny, N2
Seiter, K1
Conti, JA1
Cohen, A1
Bertino, JR1
Sigurdson, ER1
Botet, J1
Chapman, D1
Mazumdar, M1
Budd, AJ1
Weiss, AJ1
Lackman, RD1
Evrard, A1
Cuq, P1
Robert, B1
Vian, L1
Pèlegrin, A1
Cano, JP1
Leder, GH1
Pillasch, J1
Kornmann, M1
Danenberg, PV1
Link, KH1
Hara, Y1
Kawasaki, T1
Yabata, E1
Gen, T1
Jibiki, M1
Kudoh, A1
Noguchi, N1
Igarashi, K2
Kikuchi, M1
Gonen, M1
Sullivan, D1
Schwartz, L1
Benedetti, F1
Saltz, L1
Stockman, J1
Fong, Y1
Jarnagin, W1
Bertino, J1
Tong, W1
Paty, P1
Basaki, Y1
Chikahisa, L1
Aoyagi, K1
Miyadera, K1
Yonekura, K1
Hashimoto, A1
Okabe, S1
Wierzba, K1
Yamada, Y1
Gruenberger, T1
Zhao, J1
King, J1
Chung, T1
Clingan, PR1
Morris, DL1
Brockman, RW1
Shaddix, SC1
Rose, LM1
Patt, YZ1
Wallace, S1
Hersh, EM1
Hall, SW1
Menachem, YB1
Granmayeh, M1
McBride, CM1
Benjamin, RS1
Mavligit, GM1
Hiehle, JF1
Levine, MS1
Nakagawa, Y1
Peters, GJ2
Braakhuis, BJ1
Laurensse, EJ2
van Walsum, M1
Pinedo, HM2
Donegan, WL1
Simoni, G1
Bignami, P1
Civalleri, D1
Cosimelli, M1
Craus, W1
Percivale, PL1
Repetto, M1
Fujimoto, S1
Shrestha, RD1
Miyazaki, M1
Endoh, F1
Ohta, M1
Togawa, Y1
Okui, K1
Heier, MS1
Fosså, SD1
van Dijk, J1
van Groeningen, C1
Leyva, A1
Lankelma, J1
Shepard, KV1
Levin, B1
Faintuch, J1
Doria, MI1
DuBrow, RA1
Riddell, RH1
Mercer, JR1
Knaus, EE1
Wiebe, LI1
Valone, FH1
Kohler, M1
Fisher, K1
Hannigan, J1
Flam, M1
Gandara, D1
Hendrickson, C1
Richman, E1
Yu, KP1
Berne, M1
Gustavsson, B1
Almersjö, O1
Spears, P1
Sundström, E1
Park, JG1
Collins, JM1
Gazdar, AF1
Allegra, CJ1
Steinberg, SM1
Greene, RF1
Kramer, BS1
Bello, LJ1
Ginsberg, HS2
Obert, G1
Tripier, F1
Bingen, A1
Guir, J1
Lawrence, WC1
Coyle, M2
McMahon, M2
Strauss, B2
Lucas, JJ1
Kato, K1
Dolyniuk, M1
Wheeler, GP1
Bowdon, BJ1
Adamson, DJ1
Vail, MH1
Marcialis, MA1
Biondi, E1
Atzeni, A1
Schivo, ML1
Uccheddu, P1
Loddo, B1
Carter, BJ1
Koczot, FJ1
Garrison, J1
Rose, JA1
Dolin, R1
Nakajima, S1
Hamada, C1
Uetake, H1
Van Dyk, JJ1
Clarkson, BD1
Duschinsky, R1
Keller, O1
La Sala, E1
Krakoff, IH1
Rouse, HC1
Schlesinger, RW1
Poste, G1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter and Prospective Clinical Trial of Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma[NCT04522050]Phase 165 participants (Anticipated)Interventional2018-10-01Recruiting
A Phase I Study of Isolated Hepatic Perfusion With Escalating Dose Melphalan Followed by Postoperative Hepatic Arterial Floxuridine and Leucovorin for Metastatic Unresectable Colorectal Cancers of the Liver[NCT00001576]Phase 128 participants Interventional1997-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for floxuridine and Carcinoma

ArticleYear
[Current therapeutic options for liver metastasis].
    Revista medica de Chile, 2008, Volume: 136, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Catheter Ablation; Colorect

2008
New potential treatment modalities for disseminated prostatic cancer.
    The Urologic clinics of North America, 1984, Volume: 11, Issue:2

    Topics: Androgen Antagonists; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic A

1984
Infusional chemotherapy combined with recombinant human granulocyte colony stimulating factor: advantages and limitations.
    American journal of clinical oncology, 1997, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Clinical Trials as Topic; Doxorubicin; Dr

1997
Radiation sensitizers.
    Cancer, 1976, Volume: 37, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs

1976

Trials

6 trials available for floxuridine and Carcinoma

ArticleYear
Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:13

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy, Ad

2015
Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy.
    International journal of oncology, 2004, Volume: 25, Issue:6

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Pr

2004
Hepatic arterial floxuridine and leucovorin for unresectable liver metastases from colorectal carcinoma. New dose schedules and survival update.
    Cancer, 1994, Feb-15, Volume: 73, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Drug A

1994
Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, May-15, Volume: 19, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Ca

2001
Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd).
    Acta neurologica Scandinavica, 1986, Volume: 73, Issue:5

    Topics: Adult; Aged; Brain Diseases; Carcinoid Tumor; Carcinoma; Cerebellar Diseases; Colonic Neoplasms; Ele

1986
A Northern California Oncology Group randomized trial of leucovorin plus 5-fluorouracil versus sequential methotrexate, 5-fluorouracil, and leucovorin in patients with advanced colorectal cancer who failed treatment with 5-fluorouracil or 5-fluorodeoxyuri
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Drug Administration Sc

1987

Other Studies

44 other studies available for floxuridine and Carcinoma

ArticleYear
Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Jun-15, Volume: 14, Issue:12

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Pharmacological; Biomarkers, Tumor; Carcin

2008
Epstein-Barr virus latent membrane protein 1 induces the chemotherapeutic target, thymidine phosphorylase, via NF-kappaB and p38 MAPK pathways.
    Cellular signalling, 2010, Volume: 22, Issue:7

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Floxuridine; Humans; Nasopharyngeal Ne

2010
Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump.
    AJR. American journal of roentgenology, 2003, Volume: 181, Issue:2

    Topics: Aged; Angiography, Digital Subtraction; Antimetabolites, Antineoplastic; Carcinoma; Colorectal Neopl

2003
Controlled-dose therapy as an adjunct to surgery.
    Cancer, 1963, Volume: 16

    Topics: Carcinoma; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Protein Deficiency

1963
INHIBITION OF EHRLICH ASCITES TUMOR WITH 5-FLUOROURACIL AND OTHER AGENTS.
    Experimental cell research, 1963, Volume: 24

    Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; Floxuridine; Fluorouracil; Hydr

1963
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
    Cancer chemotherapy reports, 1963, Volume: 32

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona

1963
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neop

1964
FLUORINATED PYRIMIDINES. XXII. EFFECTS OF VARIOUS COMPOUNDS ON THE INCORPORATION OF (14C)FORMATE INTO DNA THYMINE IN SUSPENSIONS OF EHRLICH ASCITES CELLS.
    Biochimica et biophysica acta, 1964, Dec-16, Volume: 91

    Topics: Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA;

1964
FLUORINATED PYRIMIDINES. XXV. THE INHIBITION OF THYMIDYLATE SYNTHETASE FROM EHRLICH ASCITES CARCINOMA CELLS BY PYRIMIDINE ANALOGS.
    Biochimica et biophysica acta, 1965, May-11, Volume: 103

    Topics: Adenosine Triphosphate; Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Enzyme Inhibitors; Fl

1965
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:8

    Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal

1984
[The therapy of the liver metastases of colorectal carcinoma].
    Minerva chirurgica, 1994, Volume: 49, Issue:10 Suppl 1

    Topics: Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Colorectal Neoplasms; Combined Modality Therapy

1994
5'-Deoxy-5-fluorouridine increases daunorubicin uptake in multidrug-resistant cells and its activity is related with P-gp 170 expression.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Carrier Proteins; Colon

1994
[The evolution of the liver metastases from colorectal carcinoma treated with hepatic intra-arterial chemotherapy. The echographic and CT aspects].
    La Radiologia medica, 1994, Volume: 87, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Floxuridine; Fluoro

1994
Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study.
    International journal of cancer, 1999, Jan-29, Volume: 80, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Colonic Neoplasms; Drug Synergism; Floxuridine;

1999
Theoretical considerations and in vitro concentration response studies with two human colorectal carcinoma cell lines. The rational experimental base for clinical studies in regional chemotherapy.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic

2000
[A case of recurrent breast cancer with carcinoma erysipeloides responding to sequential therapy with docetaxel (TXT) and doxifluridine (5'-DFUR) accompanied by leucovorin (LV)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2000, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms;

2000
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
    Angiogenesis, 2001, Volume: 4, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carc

2001
Echogenicity of liver metastases from colorectal carcinoma is an independent prognostic factor in patients treated with regional chemotherapy.
    Cancer, 2002, Mar-15, Volume: 94, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma; Colorectal Neoplasms; Female; Flox

2002
Biochemical aspects of chemotherapy of mouse colon carcinoma: fluoropyrimidines and pyrazofurin.
    Cancer, 1977, Volume: 40, Issue:5 Suppl

    Topics: Amidophosphoribosyltransferase; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcino

1977
Hepatic arterial infusion of Corynebacterium parvum and chemotherapy.
    Surgery, gynecology & obstetrics, 1978, Volume: 147, Issue:6

    Topics: Antineoplastic Agents; Carcinoembryonic Antigen; Carcinoma; Catheterization; Female; Floxuridine; He

1978
Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings.
    Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, 1991, Volume: 42, Issue:2

    Topics: Aged; Carcinoma; Duodenitis; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Ileitis; Inf

1991
[Pharmacokinetics of anticancer drugs in hamsters with tongue carcinoma].
    Tsurumi shigaku. Tsurumi University dental journal, 1986, Volume: 12, Issue:2

    Topics: Animals; Bleomycin; Carcinoma; Cricetinae; Floxuridine; Kinetics; Male; Mesocricetus; Peplomycin; Ti

1986
Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes.
    British journal of cancer, 1989, Volume: 59, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma; Colonic Neoplasms; Drug Resistance; Female; Floxuridine;

1989
Hepatic artery infusion chemotherapy for colorectal metastases: a personal experience.
    Journal of surgical oncology, 1985, Volume: 30, Issue:3

    Topics: Adult; Aged; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans

1985
[Comparison of the performance of a totally implantable pump and conventional access systems in regional arterial chemotherapy of liver tumors].
    Minerva medica, 1986, Jan-14, Volume: 77, Issue:1-2

    Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Floxuridine; Humans; Infusions, I

1986
Combined therapy of polyamine antimetabolites and antitumor drugs for human gastric cancer xenotransplanted into nude mice.
    The Japanese journal of surgery, 1986, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcino

1986
Toxicity and antitumor effect of 5-fluorouracil and its rescue by uridine.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Animals; Body Temperature Regulation; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug

1986
Hepatitis in patients receiving intraarterial chemotherapy for metastatic colorectal carcinoma.
    American journal of clinical oncology, 1987, Volume: 10, Issue:1

    Topics: Bilirubin; Carcinoma; Chemical and Drug Induced Liver Injury; Colonic Neoplasms; Female; Floxuridine

1987
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Erythro

1987
Inhibition of thymidylate synthase after administration of doxifluridine in a transplantable colon carcinoma in the rat.
    Cancer investigation, 1988, Volume: 6, Issue:4

    Topics: Animals; Carcinoma; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Male

1988
Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human colorectal carcinoma cell lines.
    Journal of the National Cancer Institute, 1988, Dec-07, Volume: 80, Issue:19

    Topics: Carcinoma; Cell Survival; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; L

1988
Inhibition of host protein synthesis in type 5 adenovirus-infected cells.
    Journal of virology, 1967, Volume: 1, Issue:5

    Topics: Acid Phosphatase; Adenoviridae; Antigens; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Com

1967
[Effects of arginine deficiency on the replication of vaccinial virus].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Mar-22, Volume: 272, Issue:12

    Topics: Arginine; Carcinoma; Cell Line; DNA, Viral; Floxuridine; Humans; Microscopy, Electron; Mouth Neoplas

1971
Evidence for a relationship between equine abortion (herpes) virus deoxyribonucleic acid synthesis and the S phase of the KB cell mitotic cycle.
    Journal of virology, 1971, Volume: 7, Issue:6

    Topics: Animals; Autoradiography; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; C

1971
Failure of alkylated HEp.2 cells to replicate newly synthesized DNA.
    Mutation research, 1971, Volume: 12, Issue:4

    Topics: Alkanes; Alkylating Agents; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient;

1971
Synthesis of virus-specific ribonucleic acid in KB cells infected with type 2 adenovirus.
    Journal of virology, 1971, Volume: 8, Issue:2

    Topics: Adenoviridae; Carcinoma; Cell Line; Cell-Free System; Cells, Cultured; Centrifugation, Density Gradi

1971
DNA synthesis, repair and chromosome breaks in eucaryotic cells.
    The Johns Hopkins medical journal, 1972, Volume: 1

    Topics: Alkylating Agents; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chroma

1972
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
    Cancer research, 1972, Volume: 32, Issue:12

    Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Rep

1972
5-Iodo-2-deoxyuridine resistance of vaccinia viruses in cells endowed with thymidine kinase activity.
    Experientia, 1973, Jun-15, Volume: 29, Issue:6

    Topics: Bromodeoxyuridine; Carcinoma; Cell Line; Drug Resistance, Microbial; Floxuridine; Humans; Idoxuridin

1973
Separate helper functions provided by adenovirus for adenovirus-associated virus multiplication.
    Nature: New biology, 1973, Jul-18, Volume: 244, Issue:133

    Topics: Adenoviridae; Carcinoma; Cell Line; DNA, Viral; Floxuridine; Helper Viruses; Humans; Kinetics; Mouth

1973
Tumor-specific transplantation antigen activity of freshly adenovirus-infected cells. Intercurrent immunization against viral tumorigenesis with virus-infected cells.
    Japanese journal of microbiology, 1974, Volume: 18, Issue:3

    Topics: Adenoviridae; Animals; Animals, Newborn; Antigens, Neoplasm; Carcinoma; Cell Line; Cricetinae; Floxu

1974
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
    Cancer research, 1967, Volume: 27, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carci

1967
The effects of arginine starvation on macromolecular synthesis in infection with type 2 adenovirus. I. Synthesis and utilization of structural proteins.
    Virology, 1972, Volume: 48, Issue:2

    Topics: Adenoviridae; Adenoviridae Infections; Amino Acids; Arginine; Carbon Isotopes; Carcinoma; Cell Line;

1972
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
    Experimental cell research, 1972, Volume: 73, Issue:2

    Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transfor

1972