floxuridine has been researched along with Carcinoma 256, Walker in 12 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " At the 1st hr after dosing the 5-FU level in the small intestine was close to, but that in other tissues was much lower than, the 5-FU level in the tumor of both types." | 1.26 | Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats. ( Fukazawa, H; Hongu, Y; Ichihara, S; Shimizu, H; Suzuki, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WOLBERG, WH | 1 |
| JOHNSON, RO | 1 |
| CURRERI, AR | 1 |
| Kelley, JL | 4 |
| Baker, BR | 4 |
| Suzuki, S | 1 |
| Hongu, Y | 1 |
| Fukazawa, H | 1 |
| Ichihara, S | 1 |
| Shimizu, H | 1 |
| Nakagawa, H | 1 |
| Yamada, M | 1 |
| Fukushima, M | 1 |
| Shimizu, K | 1 |
| Ikenaka, K | 1 |
| Fogt, F | 1 |
| Wan, J | 1 |
| O'Hara, C | 1 |
| Bistrian, BR | 1 |
| Blackburn, GL | 1 |
| Istfan, NW | 1 |
| Abrams, DN | 1 |
| Lee, YW | 1 |
| Mercer, JR | 1 |
| Knaus, EE | 1 |
| Wiebe, LI | 1 |
| Miwa, M | 1 |
| Nishimura, J | 1 |
| Kamiyama, T | 1 |
| Ishitsuka, H | 1 |
| Buskirk, HH | 1 |
| Crim, JA | 1 |
| Petering, HG | 1 |
| Merritt, K | 1 |
| Johnson, AG | 1 |
| Bresnick, E | 1 |
| Thompson, UB | 1 |
12 other studies available for floxuridine and Carcinoma 256, Walker
| Article | Year |
|---|---|
Controlled-dose therapy as an adjunct to surgery.
Topics: Carcinoma; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Protein Deficiency | 1963 |
Irreversible enzyme inhibitors. 202. Candidate active-site-directed irreversible inhibitors of 5-fluoro-2'-deoxyuridine phosphorylase from Walker 256 rat tumor derived from 1-benzyl-5-(3-ethoxybenzyl)uracil.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma 256, Walker; Chemical Phenomena; Chemistry; | 1982 |
Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats.
Topics: Animals; Carcinoma 256, Walker; Female; Floxuridine; Fluorouracil; Male; Mice; Rats; Sarcoma 180; Te | 1980 |
[In vitro study on intrathecal application of 5-fluoro-2'-deoxyuridine (FdUrd) for meningeal dissemination of malignant tumor].
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Carcinoma 256, Walker; Floxuridine; Fluor | 1998 |
Flow cytometric measurement of cell cycle kinetics in rat Walker-256 carcinoma following in vivo and in vitro pulse labelling with bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Carcinoma 256, Walker; Cell Cycle; Cell Line; Cell Transformation, Neopl | 1991 |
Tumour uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models. IX. Radiolabelled 1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)uracil and 1-(2'-chloro-2'-deoxy-beta-D-ribofuranosyl)uracil.
Topics: Animals; Carbon Radioisotopes; Carcinoma 256, Walker; Chlorine; Deoxyuridine; Floxuridine; Lung Neop | 1986 |
[Conversion of 5'-deoxy-5-fluorouridine to 5-FU by pyrimidine nucleoside phosphorylases in normal and tumor tissues from rodents bearing tumors and cancer patients].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Leukemia L | 1987 |
Effect of uracil mustard and several antitumor drugs on the primary antibody response in rats and mice.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Carcinoma 256, Walker; Cyclophosphamide; Cy | 1965 |
Irreversible enzyme inhibitors. CLXIX. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 6-substituted uracils.
Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil | 1970 |
Irreversible enzyme inhibitors. CLXX. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 1-substituted uracils.
Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil | 1970 |
Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 5-substituted uracils.
Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil | 1970 |
Properties of deoxythymidine kinase partially purified from animal tumors.
Topics: Adenosine Triphosphate; Animals; Barium; Bromodeoxyuridine; Calcium Chloride; Carcinoma 256, Walker; | 1965 |