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floxuridine and Carcinoma 256, Walker

floxuridine has been researched along with Carcinoma 256, Walker in 12 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Carcinoma 256, Walker: A transplantable carcinoma of the rat that originally appeared spontaneously in the mammary gland of a pregnant albino rat, and which now resembles a carcinoma in young transplants and a sarcoma in older transplants. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
" At the 1st hr after dosing the 5-FU level in the small intestine was close to, but that in other tissues was much lower than, the 5-FU level in the tumor of both types."1.26Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats. ( Fukazawa, H; Hongu, Y; Ichihara, S; Shimizu, H; Suzuki, S, 1980)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WOLBERG, WH1
JOHNSON, RO1
CURRERI, AR1
Kelley, JL4
Baker, BR4
Suzuki, S1
Hongu, Y1
Fukazawa, H1
Ichihara, S1
Shimizu, H1
Nakagawa, H1
Yamada, M1
Fukushima, M1
Shimizu, K1
Ikenaka, K1
Fogt, F1
Wan, J1
O'Hara, C1
Bistrian, BR1
Blackburn, GL1
Istfan, NW1
Abrams, DN1
Lee, YW1
Mercer, JR1
Knaus, EE1
Wiebe, LI1
Miwa, M1
Nishimura, J1
Kamiyama, T1
Ishitsuka, H1
Buskirk, HH1
Crim, JA1
Petering, HG1
Merritt, K1
Johnson, AG1
Bresnick, E1
Thompson, UB1

Other Studies

12 other studies available for floxuridine and Carcinoma 256, Walker

ArticleYear
Controlled-dose therapy as an adjunct to surgery.
    Cancer, 1963, Volume: 16

    Topics: Carcinoma; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Protein Deficiency

1963
Irreversible enzyme inhibitors. 202. Candidate active-site-directed irreversible inhibitors of 5-fluoro-2'-deoxyuridine phosphorylase from Walker 256 rat tumor derived from 1-benzyl-5-(3-ethoxybenzyl)uracil.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:5

    Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma 256, Walker; Chemical Phenomena; Chemistry;

1982
Tissue distribution of 5'-deoxy-5-fluorouridine and derived 5-fluorouracil in tumor-bearing mice and rats.
    Gan, 1980, Volume: 71, Issue:2

    Topics: Animals; Carcinoma 256, Walker; Female; Floxuridine; Fluorouracil; Male; Mice; Rats; Sarcoma 180; Te

1980
[In vitro study on intrathecal application of 5-fluoro-2'-deoxyuridine (FdUrd) for meningeal dissemination of malignant tumor].
    No shinkei geka. Neurological surgery, 1998, Volume: 26, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Carcinoma 256, Walker; Floxuridine; Fluor

1998
Flow cytometric measurement of cell cycle kinetics in rat Walker-256 carcinoma following in vivo and in vitro pulse labelling with bromodeoxyuridine.
    Cytometry, 1991, Volume: 12, Issue:1

    Topics: Animals; Bromodeoxyuridine; Carcinoma 256, Walker; Cell Cycle; Cell Line; Cell Transformation, Neopl

1991
Tumour uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models. IX. Radiolabelled 1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)uracil and 1-(2'-chloro-2'-deoxy-beta-D-ribofuranosyl)uracil.
    The British journal of radiology, 1986, Volume: 59, Issue:699

    Topics: Animals; Carbon Radioisotopes; Carcinoma 256, Walker; Chlorine; Deoxyuridine; Floxuridine; Lung Neop

1986
[Conversion of 5'-deoxy-5-fluorouridine to 5-FU by pyrimidine nucleoside phosphorylases in normal and tumor tissues from rodents bearing tumors and cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Floxuridine; Fluorouracil; Humans; Leukemia L

1987
Effect of uracil mustard and several antitumor drugs on the primary antibody response in rats and mice.
    Journal of the National Cancer Institute, 1965, Volume: 34, Issue:6

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Carcinoma 256, Walker; Cyclophosphamide; Cy

1965
Irreversible enzyme inhibitors. CLXIX. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 6-substituted uracils.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:3

    Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil

1970
Irreversible enzyme inhibitors. CLXX. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 1-substituted uracils.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:3

    Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil

1970
Irreversible enzyme inhibitors. CLXXI. Inhibition of FUDR phosphorylase from Walker 256 rat tumor by 5-substituted uracils.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:3

    Topics: Animals; Binding Sites; Carcinoma 256, Walker; Floxuridine; Rats; Transferases; Uracil

1970
Properties of deoxythymidine kinase partially purified from animal tumors.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:10

    Topics: Adenosine Triphosphate; Animals; Barium; Bromodeoxyuridine; Calcium Chloride; Carcinoma 256, Walker;

1965