floxuridine has been researched along with Carcinoma, Non-Small Cell Lung in 8 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemcitabine and dFdU were quantified by high performance liquid chromatography with ultraviolet detection." | 2.75 | Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism. ( Boezen, HM; de Vries, EG; Groen, HJ; Maring, JG; Maurer, JM; Slijfer, M; Uges, DR; Wachters, FM, 2010) |
| "Doxifluridine is a fluoropyrimidine derivate which can be administered orally with very low toxicities." | 2.68 | Phase II study of oral doxifluridine in elderly patients with advanced non-small-cell lung cancer. ( Baldini, E; Ceribelli, A; Comella, G; Conte, PF; Falcone, A; Pfanner, E; Ricci, S; Sarcina, R; Stampino, CG; Tibaldi, C, 1996) |
| "Since cancer is mainly a disease of older persons, the incidence of malignancies of all types is expected to increase during the coming decades." | 1.29 | [Chemotherapy for older cancer patients]. ( Urushizaki, I, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maring, JG | 1 |
| Wachters, FM | 1 |
| Slijfer, M | 1 |
| Maurer, JM | 1 |
| Boezen, HM | 1 |
| Uges, DR | 1 |
| de Vries, EG | 1 |
| Groen, HJ | 1 |
| Wilson, PM | 1 |
| LaBonte, MJ | 1 |
| Lenz, HJ | 1 |
| Mack, PC | 1 |
| Ladner, RD | 1 |
| Rademaker-Lakhai, JM | 1 |
| Crul, M | 1 |
| Pluim, D | 1 |
| Sparidans, RW | 1 |
| Baas, P | 1 |
| Beijnen, JH | 1 |
| van Zandwijk, N | 1 |
| Schellens, JH | 1 |
| Marangon, E | 1 |
| Sala, F | 1 |
| Caffo, O | 1 |
| Galligioni, E | 1 |
| D'Incalci, M | 1 |
| Zucchetti, M | 1 |
| Urushizaki, I | 1 |
| Baldini, E | 1 |
| Tibaldi, C | 1 |
| Pfanner, E | 1 |
| Ricci, S | 1 |
| Falcone, A | 1 |
| Ceribelli, A | 1 |
| Sarcina, R | 1 |
| Comella, G | 1 |
| Stampino, CG | 1 |
| Conte, PF | 1 |
| Sugimoto, Y | 1 |
| Ohe, Y | 1 |
| Nishio, K | 1 |
| Ohmori, T | 1 |
| Fujiwara, Y | 1 |
| Saijo, N | 1 |
| Drings, P | 1 |
| Calcanis, A | 1 |
4 trials available for floxuridine and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2010 |
Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small- | 2005 |
Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Smal | 2008 |
Phase II study of oral doxifluridine in elderly patients with advanced non-small-cell lung cancer.
Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Sm | 1996 |
4 other studies available for floxuridine and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Inhibition of dUTPase induces synthetic lethality with thymidylate synthase-targeted therapies in non-small cell lung cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; | 2012 |
[Chemotherapy for older cancer patients].
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Ce | 1993 |
In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colony-Forming Units Assay; Colorecta | 1992 |
[Furtulon (doxifluridine) in the treatment of non-small cell bronchial carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small | 1987 |