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floxuridine and Carcinoma, Epidermoid

floxuridine has been researched along with Carcinoma, Epidermoid in 32 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Research Excerpts

ExcerptRelevanceReference
"Sixteen patients with squamous carcinoma of the cervix were prospectively treated in a Phase I study."2.68Treatment of locally advanced cervical cancer with concurrent radiation and intra-arterial chemotherapy. ( Burke, TW; Eifel, PJ; Gershenson, DM; Kavanagh, JJ; Levenback, C; McNamara, MM; Morris, M, 1995)
"Case 2: A 74-year-old female with anal squamous cell carcinoma Stage II was treated by chemoradiotherapy with tegafur/uracil, external irradiation (30 Gy) and interstitial irradiation (24 Gy)."2.42[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma]. ( Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Masuda, N; Mishima, H; Sawamura, T; Takeda, Y; Takeno, A; Tsujinaka, T, 2004)
"Oral squamous cell carcinoma (OSCC) is the major cancer of head and neck with increasing incidence and mortality in Taiwan."1.38Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma. ( Chang, KP; Chang, YS; Chen, CC; Chen, LC; Hseuh, C; Liang, Y; Wu, CS, 2012)
" The clinical evaluation of UCN-01 combined with 5-fluoropyrimidines may be of interest."1.31Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells. ( Danenberg, KD; Danenberg, PV; Grem, JL; Kao, V; Nguyen, D, 2002)
"The overall response rate was 20."1.28[Phase II study of 5'-DFUR in uterine cervical cancer and ovarian cancer]. ( Ikeda, M; Noda, K; Ochiai, K; Saito, Y; Sato, A; Suzuki, M; Takada, M; Terashima, Y; Yajima, A; Yoshida, K, 1991)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199018 (56.25)18.7374
1990's10 (31.25)18.2507
2000's2 (6.25)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, CS1
Chang, KP1
Chen, LC1
Chen, CC1
Liang, Y1
Hseuh, C1
Chang, YS1
Hasegawa, K2
Okamoto, H1
Kawamura, K1
Kato, R1
Kobayashi, Y1
Sekiya, T1
Udagawa, Y1
OETTGEN, HF1
CLIFFORD, P1
CANDLER, P1
SULLIVAN, RD2
WATKINS, E1
Takeno, A1
Mishima, H1
Ikenaga, M1
Masuda, N1
Kashiwazaki, M1
Takeda, Y1
Hirao, M1
Fujitani, K1
Sawamura, T1
Tsujinaka, T1
Oberfield, RA1
Abele, R1
Kaplan, E1
Grossenbacher, R1
Schmid, HJ1
Cavalli, F1
Perez, LM1
Mekras, JA1
Briggle, TV1
Greer, S1
Leichman, CG1
Morris, M1
Eifel, PJ1
Burke, TW1
McNamara, MM1
Levenback, C1
Kavanagh, JJ1
Gershenson, DM1
Ueda, M2
Ueki, M2
Terai, Y1
Morimoto, A1
Fujii, H1
Yoshizawa, K1
Yanagihara, T1
Hatae, M1
Noda, K2
Yajima, A2
Sato, S1
Terashima, Y2
Ochiai, K2
Sasaki, H1
Mizutani, K1
Honjo, H1
Yamamoto, T1
Ozaki, M1
Yamamoto, K1
Nishimura, R1
Kudo, T1
Kobashi, Y1
Yakushiji, M1
Sugiyama, T1
Hasuo, Y1
Onishi, Y1
Matsumoto, S1
Mashiba, H1
Okamoto, K1
Ekimoto, H1
Grem, JL1
Danenberg, KD1
Kao, V1
Danenberg, PV1
Nguyen, D1
Tsukeda, H1
Mizuno, S1
Nitta, K1
Ikeda, M1
Saito, Y1
Sato, A1
Suzuki, M1
Yoshida, K1
Takada, M1
Kubota, Y1
Miura, T1
Shuin, T1
Kinoshita, Y1
Hosaka, M1
Kondo, I1
Moriyama, M1
Fukushima, S1
Fukuoka, H1
Miyai, K1
Firestone, WM1
FitzGerald, GB2
Wick, MM2
Zhao, L1
Kaneda, T1
Tohnai, I1
Shinoda, T1
Kasuya, Y1
Matsuyama, M1
Tsai, CM1
Gazdar, AF1
Allegra, C1
Perng, RP1
Kramer, BS1
Ajani, JA1
Carrasco, CH1
Jackson, DE1
Wallace, S1
Misaki, O1
Yamada, T1
Okamoto, Y1
Goto, M1
Maeda, T1
Okamura, S1
Sugimoto, O1
Chang, YM1
Bertino, JR1
Drings, P1
Calcanis, A1
Simoni, G1
Bignami, P1
Civalleri, D1
Cosimelli, M1
Craus, W1
Percivale, PL1
Repetto, M1
Abe, Y1
Matsuzawa, T1
Ito, M1
Fujiwara, T1
Yamaguchi, K1
Hatazawa, J1
Fukuda, H1
Kubota, K1
Sato, T1
Watanuki, S1
Baker, SR1
Wheeler, RH1
Medvec, BR1
Goffinet, DR1
Bagshaw, MA1
Miller, E1
Van Dyk, JJ1
Clarkson, BD1
Duschinsky, R1
Keller, O1
La Sala, E1
Krakoff, IH1
Poste, G1

Reviews

3 reviews available for floxuridine and Carcinoma, Epidermoid

ArticleYear
[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem

2004
Prolonged infusion of fluorinated pyrimidines in gastrointestinal malignancies: a review of recent clinical trials.
    Cancer investigation, 1994, Volume: 12, Issue:2

    Topics: Carcinoma, Squamous Cell; Circadian Rhythm; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasm

1994
Clinical use of radiation sensitizing agents.
    Cancer treatment reviews, 1974, Volume: 1, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromoura

1974

Trials

2 trials available for floxuridine and Carcinoma, Epidermoid

ArticleYear
Treatment of locally advanced cervical cancer with concurrent radiation and intra-arterial chemotherapy.
    Gynecologic oncology, 1995, Volume: 57, Issue:1

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Catheters, Indwelling; Cisplatin; Combined Modality Therapy;

1995
[Effect of 5'-DFUR used concurrently in radiotherapy and immunotherapy uterine cervical cancer--pilot study. Study of 5'-DFUR for Uterine Cervical Cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:5

    Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality The

1998

Other Studies

27 other studies available for floxuridine and Carcinoma, Epidermoid

ArticleYear
Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma.
    Oral oncology, 2012, Volume: 48, Issue:6

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; CASP8 and FADD-Like Apoptosis Regulating

2012
The effect of chemotherapy or radiotherapy on thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in cancer of the uterine cervix.
    European journal of obstetrics, gynecology, and reproductive biology, 2012, Volume: 163, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Squamous Cell; Chemoradiother

2012
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
    Cancer chemotherapy reports, 1963, Volume: 32

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona

1963
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neop

1964
Intra-arterial infusion in tumors of the pelvis.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 86

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality T

1983
Phase II study of doxifluridine in advanced squamous cell carcinoma of the head and neck.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:3

    Topics: Aged; Antineoplastic Agents; Bone Marrow Diseases; Carcinoma, Squamous Cell; Drug Administration Sch

1984
Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Animals; Aspartic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Deoxycytidine; Dose-Resp

1984
Stimulatory effects of EGF and TGF-alpha on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in uterine cervical-carcinoma SKG-IIIb cells.
    International journal of cancer, 1997, Sep-17, Volume: 72, Issue:6

    Topics: Basement Membrane; Carcinoma, Squamous Cell; Chemotaxis; Collagen; Collagenases; Dose-Response Relat

1997
[Evaluation of antitumor activity of etoposide administered orally for 21 consecutive days against human uterine cancer subcutaneous and/or orthotopic xenografts in nude mice].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:9

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytoge

1999
Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
    Anti-cancer drugs, 2002, Volume: 13, Issue:3

    Topics: Alkaloids; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Deo

2002
Susceptibilities of normal and malignant human lung cells in culture to the cytocidal action of antitumor agents.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Doxorubicin; Drug Evaluat

1978
[Phase II study of 5'-DFUR in uterine cervical cancer and ovarian cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:15

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Administration, Oral; Adult; Aged; Antineoplastic Agents;

1991
[Phase II study of 5'-DFUR (Furtulon) capsule for bladder cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:13

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Carcinoma, Squamous

1991
A comparison of the effects of antitumor agents upon normal human epidermal keratinocytes and human squamous cell carcinoma.
    The Journal of investigative dermatology, 1990, Volume: 94, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; DNA; DNA, Neoplasm; Floxuridine; Humans; Keratin

1990
[Experimental study relating to the anti-cancer effect of doxifluridine].
    Nihon Gan Chiryo Gakkai shi, 1990, Jun-20, Volume: 25, Issue:6

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Screening Assay

1990
Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human lung cancer cell lines.
    International journal of cancer, 1990, Jul-15, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Carcinoma, Squamous Cell; Cell Line; Dose-Respo

1990
Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal.
    The American journal of medicine, 1989, Volume: 87, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp

1989
[In vitro studies of 5-FU sensitivity on uterine cervical cancer cell lines--comparison between squamous cell carcinoma and adenocarcinoma].
    Nihon Sanka Fujinka Gakkai zasshi, 1989, Volume: 41, Issue:9

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cell Survival; DNA, Neoplasm; Drug Screening Assays, Antit

1989
Enhancement of fluoropyrimidine inhibition of cell growth by leucovorin and deoxynucleosides in a human squamous cell carcinoma cell line.
    Cancer investigation, 1989, Volume: 7, Issue:6

    Topics: Carcinoma, Squamous Cell; Culture Media; Deoxyribonucleosides; Drug Synergism; Floxuridine; Fluorour

1989
[Furtulon (doxifluridine) in the treatment of non-small cell bronchial carcinoma].
    Onkologie, 1987, Volume: 10, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small

1987
[Comparison of the performance of a totally implantable pump and conventional access systems in regional arterial chemotherapy of liver tumors].
    Minerva medica, 1986, Jan-14, Volume: 77, Issue:1-2

    Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Floxuridine; Humans; Infusions, I

1986
Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
    The Journal of investigative dermatology, 1987, Volume: 88, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyuracil Nucleotides; Depression, Chemical; DNA Rep

1987
[Cancer detection with 18F-5-fluorodeoxyuridine--a new cancer diagnostic agent reflecting nucleic acid metabolism].
    Kaku igaku. The Japanese journal of nuclear medicine, 1985, Volume: 22, Issue:5

    Topics: Carcinoma, Small Cell; Carcinoma, Squamous Cell; Floxuridine; Fluorine; Humans; Lung Neoplasms; Nucl

1985
Surgical aspects of intra-arterial chemotherapy of outpatients with head and neck cancer.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1985, Volume: 93, Issue:2

    Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin

1985
The clinical effects of prolonged intravenous infusion of 5-fluoro-2'-deoxyuridine.
    Cancer research, 1965, Volume: 25, Issue:7

    Topics: Adenoma, Islet Cell; Aged; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Fl

1965
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
    Cancer research, 1967, Volume: 27, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carci

1967
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
    Experimental cell research, 1972, Volume: 73, Issue:2

    Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transfor

1972