floxuridine has been researched along with Carcinoma, Epidermoid in 32 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen patients with squamous carcinoma of the cervix were prospectively treated in a Phase I study." | 2.68 | Treatment of locally advanced cervical cancer with concurrent radiation and intra-arterial chemotherapy. ( Burke, TW; Eifel, PJ; Gershenson, DM; Kavanagh, JJ; Levenback, C; McNamara, MM; Morris, M, 1995) |
| "Case 2: A 74-year-old female with anal squamous cell carcinoma Stage II was treated by chemoradiotherapy with tegafur/uracil, external irradiation (30 Gy) and interstitial irradiation (24 Gy)." | 2.42 | [Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma]. ( Fujitani, K; Hirao, M; Ikenaga, M; Kashiwazaki, M; Masuda, N; Mishima, H; Sawamura, T; Takeda, Y; Takeno, A; Tsujinaka, T, 2004) |
| "Oral squamous cell carcinoma (OSCC) is the major cancer of head and neck with increasing incidence and mortality in Taiwan." | 1.38 | Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma. ( Chang, KP; Chang, YS; Chen, CC; Chen, LC; Hseuh, C; Liang, Y; Wu, CS, 2012) |
| " The clinical evaluation of UCN-01 combined with 5-fluoropyrimidines may be of interest." | 1.31 | Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells. ( Danenberg, KD; Danenberg, PV; Grem, JL; Kao, V; Nguyen, D, 2002) |
| "The overall response rate was 20." | 1.28 | [Phase II study of 5'-DFUR in uterine cervical cancer and ovarian cancer]. ( Ikeda, M; Noda, K; Ochiai, K; Saito, Y; Sato, A; Suzuki, M; Takada, M; Terashima, Y; Yajima, A; Yoshida, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (56.25) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, CS | 1 |
| Chang, KP | 1 |
| Chen, LC | 1 |
| Chen, CC | 1 |
| Liang, Y | 1 |
| Hseuh, C | 1 |
| Chang, YS | 1 |
| Hasegawa, K | 2 |
| Okamoto, H | 1 |
| Kawamura, K | 1 |
| Kato, R | 1 |
| Kobayashi, Y | 1 |
| Sekiya, T | 1 |
| Udagawa, Y | 1 |
| OETTGEN, HF | 1 |
| CLIFFORD, P | 1 |
| CANDLER, P | 1 |
| SULLIVAN, RD | 2 |
| WATKINS, E | 1 |
| Takeno, A | 1 |
| Mishima, H | 1 |
| Ikenaga, M | 1 |
| Masuda, N | 1 |
| Kashiwazaki, M | 1 |
| Takeda, Y | 1 |
| Hirao, M | 1 |
| Fujitani, K | 1 |
| Sawamura, T | 1 |
| Tsujinaka, T | 1 |
| Oberfield, RA | 1 |
| Abele, R | 1 |
| Kaplan, E | 1 |
| Grossenbacher, R | 1 |
| Schmid, HJ | 1 |
| Cavalli, F | 1 |
| Perez, LM | 1 |
| Mekras, JA | 1 |
| Briggle, TV | 1 |
| Greer, S | 1 |
| Leichman, CG | 1 |
| Morris, M | 1 |
| Eifel, PJ | 1 |
| Burke, TW | 1 |
| McNamara, MM | 1 |
| Levenback, C | 1 |
| Kavanagh, JJ | 1 |
| Gershenson, DM | 1 |
| Ueda, M | 2 |
| Ueki, M | 2 |
| Terai, Y | 1 |
| Morimoto, A | 1 |
| Fujii, H | 1 |
| Yoshizawa, K | 1 |
| Yanagihara, T | 1 |
| Hatae, M | 1 |
| Noda, K | 2 |
| Yajima, A | 2 |
| Sato, S | 1 |
| Terashima, Y | 2 |
| Ochiai, K | 2 |
| Sasaki, H | 1 |
| Mizutani, K | 1 |
| Honjo, H | 1 |
| Yamamoto, T | 1 |
| Ozaki, M | 1 |
| Yamamoto, K | 1 |
| Nishimura, R | 1 |
| Kudo, T | 1 |
| Kobashi, Y | 1 |
| Yakushiji, M | 1 |
| Sugiyama, T | 1 |
| Hasuo, Y | 1 |
| Onishi, Y | 1 |
| Matsumoto, S | 1 |
| Mashiba, H | 1 |
| Okamoto, K | 1 |
| Ekimoto, H | 1 |
| Grem, JL | 1 |
| Danenberg, KD | 1 |
| Kao, V | 1 |
| Danenberg, PV | 1 |
| Nguyen, D | 1 |
| Tsukeda, H | 1 |
| Mizuno, S | 1 |
| Nitta, K | 1 |
| Ikeda, M | 1 |
| Saito, Y | 1 |
| Sato, A | 1 |
| Suzuki, M | 1 |
| Yoshida, K | 1 |
| Takada, M | 1 |
| Kubota, Y | 1 |
| Miura, T | 1 |
| Shuin, T | 1 |
| Kinoshita, Y | 1 |
| Hosaka, M | 1 |
| Kondo, I | 1 |
| Moriyama, M | 1 |
| Fukushima, S | 1 |
| Fukuoka, H | 1 |
| Miyai, K | 1 |
| Firestone, WM | 1 |
| FitzGerald, GB | 2 |
| Wick, MM | 2 |
| Zhao, L | 1 |
| Kaneda, T | 1 |
| Tohnai, I | 1 |
| Shinoda, T | 1 |
| Kasuya, Y | 1 |
| Matsuyama, M | 1 |
| Tsai, CM | 1 |
| Gazdar, AF | 1 |
| Allegra, C | 1 |
| Perng, RP | 1 |
| Kramer, BS | 1 |
| Ajani, JA | 1 |
| Carrasco, CH | 1 |
| Jackson, DE | 1 |
| Wallace, S | 1 |
| Misaki, O | 1 |
| Yamada, T | 1 |
| Okamoto, Y | 1 |
| Goto, M | 1 |
| Maeda, T | 1 |
| Okamura, S | 1 |
| Sugimoto, O | 1 |
| Chang, YM | 1 |
| Bertino, JR | 1 |
| Drings, P | 1 |
| Calcanis, A | 1 |
| Simoni, G | 1 |
| Bignami, P | 1 |
| Civalleri, D | 1 |
| Cosimelli, M | 1 |
| Craus, W | 1 |
| Percivale, PL | 1 |
| Repetto, M | 1 |
| Abe, Y | 1 |
| Matsuzawa, T | 1 |
| Ito, M | 1 |
| Fujiwara, T | 1 |
| Yamaguchi, K | 1 |
| Hatazawa, J | 1 |
| Fukuda, H | 1 |
| Kubota, K | 1 |
| Sato, T | 1 |
| Watanuki, S | 1 |
| Baker, SR | 1 |
| Wheeler, RH | 1 |
| Medvec, BR | 1 |
| Goffinet, DR | 1 |
| Bagshaw, MA | 1 |
| Miller, E | 1 |
| Van Dyk, JJ | 1 |
| Clarkson, BD | 1 |
| Duschinsky, R | 1 |
| Keller, O | 1 |
| La Sala, E | 1 |
| Krakoff, IH | 1 |
| Poste, G | 1 |
3 reviews available for floxuridine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Chem | 2004 |
Prolonged infusion of fluorinated pyrimidines in gastrointestinal malignancies: a review of recent clinical trials.
Topics: Carcinoma, Squamous Cell; Circadian Rhythm; Cisplatin; Clinical Trials as Topic; Colorectal Neoplasm | 1994 |
Clinical use of radiation sensitizing agents.
Topics: Animals; Antimetabolites, Antineoplastic; Bleomycin; Bromodeoxycytidine; Bromodeoxyuridine; Bromoura | 1974 |
2 trials available for floxuridine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Treatment of locally advanced cervical cancer with concurrent radiation and intra-arterial chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Catheters, Indwelling; Cisplatin; Combined Modality Therapy; | 1995 |
[Effect of 5'-DFUR used concurrently in radiotherapy and immunotherapy uterine cervical cancer--pilot study. Study of 5'-DFUR for Uterine Cervical Cancer].
Topics: Adjuvants, Immunologic; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality The | 1998 |
27 other studies available for floxuridine and Carcinoma, Epidermoid
| Article | Year |
|---|---|
Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; CASP8 and FADD-Like Apoptosis Regulating | 2012 |
The effect of chemotherapy or radiotherapy on thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in cancer of the uterine cervix.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Squamous Cell; Chemoradiother | 2012 |
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona | 1963 |
PROTRACTED ARTERIAL INFUSION CANCER CHEMOTHERAPY.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Catheterization; Colonic Neop | 1964 |
Intra-arterial infusion in tumors of the pelvis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality T | 1983 |
Phase II study of doxifluridine in advanced squamous cell carcinoma of the head and neck.
Topics: Aged; Antineoplastic Agents; Bone Marrow Diseases; Carcinoma, Squamous Cell; Drug Administration Sch | 1984 |
Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis.
Topics: Animals; Aspartic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Deoxycytidine; Dose-Resp | 1984 |
Stimulatory effects of EGF and TGF-alpha on invasive activity and 5'-deoxy-5-fluorouridine sensitivity in uterine cervical-carcinoma SKG-IIIb cells.
Topics: Basement Membrane; Carcinoma, Squamous Cell; Chemotaxis; Collagen; Collagenases; Dose-Response Relat | 1997 |
[Evaluation of antitumor activity of etoposide administered orally for 21 consecutive days against human uterine cancer subcutaneous and/or orthotopic xenografts in nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytoge | 1999 |
Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Deo | 2002 |
Susceptibilities of normal and malignant human lung cells in culture to the cytocidal action of antitumor agents.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Doxorubicin; Drug Evaluat | 1978 |
[Phase II study of 5'-DFUR in uterine cervical cancer and ovarian cancer].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Administration, Oral; Adult; Aged; Antineoplastic Agents; | 1991 |
[Phase II study of 5'-DFUR (Furtulon) capsule for bladder cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Agents; Carcinoma, Squamous | 1991 |
A comparison of the effects of antitumor agents upon normal human epidermal keratinocytes and human squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cell Division; Cell Line; DNA; DNA, Neoplasm; Floxuridine; Humans; Keratin | 1990 |
[Experimental study relating to the anti-cancer effect of doxifluridine].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Screening Assay | 1990 |
Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human lung cancer cell lines.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Carcinoma, Squamous Cell; Cell Line; Dose-Respo | 1990 |
Combination of cisplatin plus fluoropyrimidine chemotherapy effective against liver metastases from carcinoma of the anal canal.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell; Cisp | 1989 |
[In vitro studies of 5-FU sensitivity on uterine cervical cancer cell lines--comparison between squamous cell carcinoma and adenocarcinoma].
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cell Survival; DNA, Neoplasm; Drug Screening Assays, Antit | 1989 |
Enhancement of fluoropyrimidine inhibition of cell growth by leucovorin and deoxynucleosides in a human squamous cell carcinoma cell line.
Topics: Carcinoma, Squamous Cell; Culture Media; Deoxyribonucleosides; Drug Synergism; Floxuridine; Fluorour | 1989 |
[Furtulon (doxifluridine) in the treatment of non-small cell bronchial carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small | 1987 |
[Comparison of the performance of a totally implantable pump and conventional access systems in regional arterial chemotherapy of liver tumors].
Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Squamous Cell; Female; Floxuridine; Humans; Infusions, I | 1986 |
Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyuracil Nucleotides; Depression, Chemical; DNA Rep | 1987 |
[Cancer detection with 18F-5-fluorodeoxyuridine--a new cancer diagnostic agent reflecting nucleic acid metabolism].
Topics: Carcinoma, Small Cell; Carcinoma, Squamous Cell; Floxuridine; Fluorine; Humans; Lung Neoplasms; Nucl | 1985 |
Surgical aspects of intra-arterial chemotherapy of outpatients with head and neck cancer.
Topics: Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin | 1985 |
The clinical effects of prolonged intravenous infusion of 5-fluoro-2'-deoxyuridine.
Topics: Adenoma, Islet Cell; Aged; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Fl | 1965 |
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carci | 1967 |
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transfor | 1972 |