floxuridine has been researched along with Cancer of Stomach in 180 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The concentration of paclitaxel in the ascites was maintained between 0." | 9.15 | Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites. ( Ishikawa, H; Iwazaki, S; Izumi, M; Kakinuma, S; Kamoshita, N; Kawate, S; Kobayashi, I; Kobayashi, J; Makita, F; Nakagami, K; Ohya, T; Okabe, T; Sakamoto, I; Sato, Y; Sunose, Y; Takeyoshi, I; Tanahashi, Y; Tomizawa, N; Yamada, T; Yoshinari, D, 2011) |
| "A 71-year-old man with Borrmann type 3 gastric cancer and peritonitis carcinomatosa was treated with 5'-DFUR 600 mg/body p." | 5.30 | [Successful 5'-DFUR, CDDP and MMC combination therapy and 5'-DFUR and carboplatin combination therapy for a patient with inoperable advanced gastric cancer with peritonitis carcinomatosa]. ( Ando, S; Katanuma, A; Maekubo, H; Mori, M; Tsuji, K, 1997) |
| " The concentration of paclitaxel in the ascites was maintained between 0." | 5.15 | Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites. ( Ishikawa, H; Iwazaki, S; Izumi, M; Kakinuma, S; Kamoshita, N; Kawate, S; Kobayashi, I; Kobayashi, J; Makita, F; Nakagami, K; Ohya, T; Okabe, T; Sakamoto, I; Sato, Y; Sunose, Y; Takeyoshi, I; Tanahashi, Y; Tomizawa, N; Yamada, T; Yoshinari, D, 2011) |
| "Fifty-nine patients with invasive primary gastric adenocarcinoma who were deemed resectable for cure entered a clinical trial that called for 2 cycles of protracted infusion 5-fluorouracil with weekly leucovorin and cisplatin chemotherapy followed by surgery." | 5.08 | Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report. ( Baranda, J; Casagrande, Y; Crookes, P; Groshen, S; Laine, L; Leichman, CG; Leichman, L; Silberman, H; Stain, S; Tan, M, 1997) |
| "The figures in patients with breast cancer were: 1,761 days (58." | 3.78 | [Survival and changes of clinical laboratory data in phase II study with 5'-DFUR]. ( Taguchi, T, 1996) |
| " Using a murine dorsal air sac (DAS) assay, we have previously shown that UFT and its metabolites, gamma-hydroxybutyric acid (GHB) and 5-fluorouracil (5-FU), inhibited the angiogenesis induced by murine renal cell carcinoma." | 3.71 | gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor. ( Aoyagi, K; Basaki, Y; Chikahisa, L; Hashimoto, A; Miyadera, K; Okabe, S; Wierzba, K; Yamada, Y; Yonekura, K, 2001) |
| " Following our former report in which the combination effects of mitomycin C (MMC) and 5'-deoxy-5-fluorouridine (5'-DFUR) were clarified, combined applications of 4 drugs, vindesine (VDS), methotrexate (MTX), cisplatin (CDDP) and 5'-DFUR against 3 lines of human breast cancer (H-62, H-31, H-71), and one line each of gastric cancer (H-55) and colon cancer (H-110) xenografted into nude mice were evaluated in comparison with CAF (cyclophosphamide, adriamycin and 5-FU) therapy which is commonly used for breast cancer." | 3.67 | [Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)]. ( Fujita, F; Fujita, M; Inaba, H; Sakamoto, Y; Shimozuma, K; Taguchi, T, 1987) |
| "Sixty gastric cancer patients were divided randomly into three groups (20 each group) before operation: group one:5'-DFUR oral administration at the dose of 800-1200 mg/d for 3 - 5 d, group two: 500 mg 5-FU + 200 mg/d CF by venous drip for 3 - 5 d,group three (control group)." | 2.72 | Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action. ( Ding, W; Luo, B; Ma, ZM; Sheng, JM; Teng, LS; Wang, M; Wang, SF; Wu, FS; Zhao, WH, 2006) |
| " A further six patients were added in order to confirm the safety of this dosage level, and no more DLTs except for grade 3 nausea in one patient were observed in the second cohort." | 2.71 | A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer. ( Endo, S; Hidaka, S; Hirao, K; Hirasaki, S; Hyodo, I; Kajiwara, T; Kurita, A; Masumoto, T; Moriwaki, T; Nasu, J; Nishina, T; Tsuzuki, T, 2005) |
| "Patients with inoperable gastric cancer were given either of two regimens of combined 5'-deoxy-5-fluorouridine and cisplatin with different dose intensities." | 2.69 | [Two regimens of combined 5'-deoxy-5-fluorouridine and cisplatin showing different dose intensities--investigation based on relative performances]. ( Koizumi, W; Kokutou, M; Koshida, Y; Kurihara, M; Saigenji, K; Soh, I; Tanabe, S; Tanigawa, H; Watanabe, M, 1999) |
| "Patients with 24 advanced gastric cancers and 36 colonic cancers were randomly divided into a preoperatively administered group and a non-administered group." | 2.68 | [Significance of 5'-deoxy-5-fluorouridine (5'-DFUR) administration before surgery for advanced gastric and colonic cancers--activity of pyrimidine nucleoside phosphorylase (PyNPase) and serum immunosuppressive acidic protein (IAP)]. ( Arano, Y; Hirano, M; Ishikawa, N; Kikuchi, T; Kitsukawa, H; Kurokawa, M; Murakami, N; Nagao, S; Saito, H, 1996) |
| "A clinical trial for patients with gastric cancer amenable to curative resection was undertaken to determine feasibility and response to preoperative systemic chemotherapy followed by postoperative intraperitoneal (IP) chemotherapy." | 2.67 | Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program. ( Kiyabu, M; Laine, L; Leichman, CG; Leichman, L; Muggia, FM; Radin, R; Ray, M; Silberman, H; Spears, CP; Stain, S, 1992) |
| " Combination with high-dose 5'-DFUR and low-dose intra-hepatic arterial infusion of CDDP is considered a very effective chemotherapy which can be performed ambulatorily while maintaining the quality of life of patients with liver metastases of gastric cancer." | 2.67 | [Combination with intra-hepatic arterial infusion of low-dose cisplatin and oral administration of high-dose doxyfluridine in patients with liver metastases of gastric cancer]. ( Kikkawa, N; Kobayashi, K; Mishima, H; Shin, E; Takatsuka, Y; Tamaki, Y; Tono, T; Yagyu, T, 1994) |
| "Twenty-one stomach cancer patients and 34 colorectal cancer patients were registered in the study." | 2.67 | [Study of 5'-DFUR treatment as postoperative adjuvant chemotherapy for stomach and colorectal cancer. Tokai GATS Group (pilot study)]. ( Hachisuka, K; Honda, H; Honda, K; Maeda, A; Nakazato, H; Tsuruga, N; Yamaguchi, A; Yoshizaki, S; Yura, J, 1994) |
| "Leukocytopenia was more severe in group B." | 2.67 | [Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy] ( Ito, T; Komatsu, Y; Moriya, N; Ogasawara, H; Saito, S; Sakata, Y; Sugimoto, N; Tamura, Y; Tsushima, K; Yamada, Y, 1994) |
| "To investigate the optimal dosage schedule for 5'-deoxy-5-fluorouridine (5'-DFUR), a randomized comparative study was performed in patients with inoperable or advanced gastric cancer." | 2.66 | [Randomized comparison of continuous and intermittent oral administration of 5'-deoxy-5-fluorouridine in the treatment of advanced gastric cancer; a phase II trial by the Multi-institutional Cooperative Study Group]. ( Hasegawa, K; Hatta, Y; Kawachi, M; Kurihara, M; Niitani, H; Suwa, T; Taguchi, S; Tsuboi, E; Yasui, A; Yoshimori, K, 1987) |
| "5'-DFUR was administered orally to advanced or recurrent cancer patients at a daily dosage of 600-1200 mg divided into 3 or 4 times a day." | 2.66 | [Clinical trial of 5'-deoxy-5-fluorouridine (5'-DFUR) in advanced cancer patients]. ( Imamura, Y; Irie, K; Nakamura, T; Suehiro, I; Yasutake, K; Yoshida, M; Yoshimura, Y, 1985) |
| "We report here a very rare case of chronic myeloid leukemia (CML) following long-term chemotherapy with 5'-deoxy-5-fluorouridine (5'-DFUR) for gastric cancer." | 2.44 | Chronic myeloid leukemia following chemotherapy with 5'-deoxy-5-fluorouridine for gastric cancer. ( Emi, N; Ezaki, K; Handa, K; Hasegawa, A; Maruyama, F; Mizuta, S; Okamoto, M; Tsuzuki, M; Watanabe, M; Yamamoto, K; Yamamoto, Y, 2008) |
| "Whether gastric cancer in young adults differs from gastric cancer in older patients has been a controversial issue." | 2.41 | Gastric cancer in very young adults: apropos four patients and a review of the literature. ( Fiehler, J; Höffken, K; Kath, R; Schneider, CP, 2000) |
| "Mean time from gastric cancer diagnosis to liver metastasis was significantly longer in the TAI group (n = 13) than in the systemic chemotherapy group (n = 29); 944 ± 231 days versus 506 ± 77 days." | 1.38 | The effect of locoregional transarterial infusion chemotherapy on liver metastasis after gastric cancer resection. ( Kan, ZX; Liu, R; Qian, S; Wang, JH; Wang, YY; Zhang, W, 2012) |
| "He had type 3 gastric cancer on the posterior wall of vestibular part." | 1.38 | [A case report of complete response by weekly paclitaxel and 5'-DFUR combination chemotherapy for recurrenced gastric cancer with peritoneal dissemination]. ( Kondo, J; Nagashima, Y; Nakamura, M; Nishimura, T; Okada, T; Sakata, K, 2012) |
| "Paclitaxel was administered at a dose of 80 mg/m(2) on day 1, 8 and 15, and doxifluridine was orally administered at a dose of 533 mg/m(2) day for five days followed by withdrawal for two days." | 1.35 | [A case of complete response for advanced gastric cancer with liver metastasis treated with combination chemotherapy of weekly paclitaxel and doxifluridine]. ( Higuchi, T; Iesato, H; Kawate, S; Matsumoto, H; Numaga, Y; Ohya, T; Okabe, T; Tago, K; Takeyoshi, I; Totsuka, O; Yokomori, T, 2009) |
| "A 82-year-old man with advanced gastric cancer underwent distal gastrectomy in January 2006." | 1.35 | [Complete response obtained with first-line therapy as S-1, followed by second-line 5'-DFUR plus paclitaxel therapy in a patient with multiple liver and lymph node metastases from gastric cancer]. ( Kitajima, Y; Miyazaki, K; Nakafusa, Y; Ohtsuka, T; Sato, S; Tanaka, M; Yakabe, T, 2009) |
| "Many patients with gastric cancer respond to TS-1, but some fail to respond or have recurrence." | 1.34 | Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1. ( Arai, W; Haruta, H; Hirashima, Y; Hosoya, Y; Hyodo, M; Kurashina, K; Nagai, H; Saito, S; Sakuma, K; Yasuda, Y; Yokoyama, T; Zuiki, T, 2007) |
| "In advanced gastric cancer, the frequency of relapses such as metastasis to the peritoneum is high." | 1.33 | [Prediction and treatment of peritoneal dissemination in gastric cancer]. ( Aratake, K; Itabashi, M; Kameoka, S; Mitsuhashi, M; Ogawa, S; Seshimo, A; Shirotani, N, 2005) |
| "We designed a new regimen to evaluate the efficacy and feasibility of weekly paclitaxel combined with orally administered 5'-DFUR therapy against advanced and recurrent gastric cancer." | 1.33 | [Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study]. ( Deguchi, Y; Kamimura, K; Kaneko, I; Kii, E; Murata, T; Tsubono, M; Yasumizu, R, 2005) |
| "Type 3 gastric cancer in the midgastric region was diagnosed, and the patient underwent surgery." | 1.33 | [A long-term survivor with stage IV gastric cancer due to postoperative weekly paclitaxel and 5'-DFUR combination therapy]. ( Fukasawa, T; Gotoh, H; Shoji, T; Taniwaka, K, 2006) |
| " Our hypothesis was that a relatively short and high dosage of TAS-102 results in an additional mechanism of FTD incorporation into DNA other than thymidylate synthase (TS) inhibition." | 1.32 | A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA. ( Emura, T; Fukushima, M; Ohshimo, H; Suzuki, N; Yamaguchi, M, 2004) |
| " Pharmacokinetic studies after administration of S-1 revealed high and prolonged plasma 5-FU levels." | 1.32 | S-1-induced, prolonged complete regression of lung metastasis from gastric cancer refractory to 5'-DFUR: a case report with pharmacokinetic study. ( Ajani, JA; Itoh, N; Itoi, H; Shirasaka, T; Ueda, Y; Yamagishi, H; Yamashita, T, 2004) |
| " The anti-tumor effective dosage of P5, P6 and their mixture, P5+P6, were obtained in dose-dependent manner." | 1.32 | Therapeutic effects of novel anti-tumor reagent, apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line on human gastric carcinoma-bearing SCID mice. ( Guo, M; Jin, A; Mori, E; Mori, T; Qi, Y; Takasaki, S, 2004) |
| "administration in peritoneal gastric cancer (MKN45) xenografts." | 1.32 | Comparison of intraperitoneal continuous infusion of floxuridine and bolus administration in a peritoneal gastric cancer xenograft model. ( Inoue, K; Kato, Y; Machida, Y; Michiura, T; Nakai, K; Nakane, Y; Onishi, H; Sato, M; Yamamichi, K, 2004) |
| "Paclitaxel was infused at a dose of 100-130 mg after short premedication and continued for 2-3 weeks with a 1 week rest." | 1.32 | [A case of advanced gastric cancer successfully treated with neoadjuvant chemotherapy of combined weekly paclitaxel and doxifluridine (5'-DFUR)]. ( Hata, T; Hikino, H; Kanazawa, A; Nagaoka, S; Nakamura, K; Ozaki, N; Sugimoto, S; Tokuka, A; Yamada, T, 2004) |
| "The results of treatment of gastric cancer with docetaxel have scarcely been reported." | 1.31 | [A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine]. ( Ideguchi, K; Ikeda, Y; Mori, T; Nakagawa, K; Okamoto, K; Sakata, K; Yasumitsu, T, 2002) |
| "Two patients with liver metastasis from gastric cancer who responded remarkably to a combined therapy of 5'-DFUR and PSK are reported." | 1.31 | [Two patients with liver metastasis from gastric cancer who responded remarkably to combined therapy of 5'-DFUR and PSK]. ( Arai, K; Inoue, S; Iwasaki, Y; Kawahara, Y; Kitamura, M; Maeshiro, T; Miyamoto, Y; Ohashi, M; Saiura, A; Takahashi, T; Tanaka, S; Umekita, N, 2000) |
| "We report a case of advanced gastric cancer with multiple liver metastases and peritoneal dissemination." | 1.31 | [Effectiveness of high-dose, intermittent 5'-DFUR therapy for advanced gastric cancer]. ( Emoto, K; Etoh, T; Ichiba, Y; Imaoka, Y; Ishizaki, Y; Sumimoto, R; Takahashi, M; Tokumoto, N, 2001) |
| "In the field of gastric cancer treatment, especially for patients showing multiple resistance to anticancer drugs, an effective therapy is critically needed." | 1.31 | Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens. ( Kurihara, M; Matsukawa, M; Nakamachi, M; Sato, A; Shimada, K; Ushio, J; Yamamoto, W, 2002) |
| "A 71-year-old man with Borrmann type 3 gastric cancer and peritonitis carcinomatosa was treated with 5'-DFUR 600 mg/body p." | 1.30 | [Successful 5'-DFUR, CDDP and MMC combination therapy and 5'-DFUR and carboplatin combination therapy for a patient with inoperable advanced gastric cancer with peritonitis carcinomatosa]. ( Ando, S; Katanuma, A; Maekubo, H; Mori, M; Tsuji, K, 1997) |
| "A 71-year-old man with Borrmann type 3 gastric cancer with multiple liver metastases had been treated with 5'-DFUR 1400 mg/m2/day, p." | 1.29 | [A successful 5'-DFUR and CDDP combination therapy for an advanced gastric cancer complicated with multiple liver metastases]. ( Ishihata, R; Kasukawa, R; Kuwana, T; Nishimaki, T; Obara, K, 1995) |
| "A 64-year-old male was found to have a gastric cancer (Borrmann type 3) on the posterior wall of the stomach." | 1.29 | [A case of advanced gastric cancer with liver metastasis disappeared by oral administration of 5'-deoxy-5-fluorouridine after absolute non-curative operation]. ( Matoba, N; Nagata, T; Niiyama, H; Yoshida, J, 1994) |
| "The frequency of multiple early gastric cancer occurring in patients who had not received chemotherapy was 11." | 1.29 | The significance of preoperative chemotherapy for early gastric carcinoma. ( Kumagai, K; Masuo, K; Nishida, Y; Yasui, A; Yoshitoshi, A, 1993) |
| "We reported a patient with advanced gastric cancer and a liver metastasis, who responded remarkably to combination chemotherapy using THP, 5'-DFUR and CDDP." | 1.29 | [A case of advanced gastric cancer successfully treated with combination chemotherapy using THP, 5'-DFUR and CDDP, followed by surgical resection]. ( Adachi, H; Kobori, O; Kurihara, M; Kurihara, T; Murakami, H; Saito, K; Tamura, Y, 1995) |
| "She was diagnosed as having an advanced gastric cancer, which was unresectable because of liver metastasis, esophageal invasion and paraaortic lymph node metastasis." | 1.29 | [Unresectable gastric cancer followed by remarkably effective tumor disappearance and good quality of life for 10 months after CDDP/5'-DFUR combination chemotherapy--a case report]. ( Hoshino, K; Ikeda, H; Kamoshita, N; Kobayashi, J; Koyama, T; Morishita, Y; Nakamura, M; Tanaka, T, 1996) |
| "When this agent is administered to gastric cancer patients, it can be expected to be more effective in the above types of patients because of its characteristics." | 1.29 | [Study on pyrimidine nucleoside phosphorylase (PyNPase) activity in resected tissues of patients with gastric cancer]. ( Ishikawa, S; Katsube, T; Konno, S; Miura, K; Naritaka, Y; Ogawa, K; Shimakawa, T; Wagatsuma, Y; Wakasugi, S; Watanabe, T, 1995) |
| "However, metastatic bone tumors from gastric cancer usually resist any treatments." | 1.28 | [A case of gastric cancer with recurrent bone metastases successfully treated with induced hypertension chemotherapy using cisplatin]. ( Furuya, K; Kashu, Y; Kiyasu, Y; Moriuchi, A; Sakai, K; Satoh, H; Shigematsu, S; Tanaka, T, 1992) |
| "Twenty-five patients with advanced gastric cancer were treated with a combination chemotherapy." | 1.28 | [The changes in tumor markers such as serum CEA, CA 19-9, TPA and CA 125 in the chemotherapy of patients with advanced gastric cancer]. ( Imamura, Y; Masuda, T; Matsushita, K; Ohno, S; Oya, M; Tokisue, M; Yasutake, K; Yoshimura, Y, 1990) |
| "5'-DFUR was administered orally at 800 mg/day, for total dosage of 57." | 1.28 | [A resected case of gastric carcinoma with complete remission of Virchow's node metastasis by 5'-DFUR administration]. ( Fukuda, H; Kitahara, T; Nagamine, H; Nakaguchi, K; Nakano, Y; Onoe, K, 1990) |
| "In case of breast cancer, it was 10 times higher than normal tissue." | 1.28 | [A study on pre-operative administration of 5'-DFUR in carcinomas of the gastric, breast, thyroid and colon]. ( Adachi, I; Douden, K; Hayashi, H; Hikishima, H; Iwa, T; Munemoto, Y; Okada, Y; Omura, K; Watanabe, Y, 1990) |
| "We describe a case of gastric cancer with multiple liver metastasis that clearly decreased in size after administration of 5'-DFUR." | 1.28 | [A case report; 5'-DFUR reduced gastric cancer with multiple liver metastasis]. ( Itoh, N; Kurimoto, N; Tamura, T; Yasuzawa, Y; Yoshimoto, I, 1992) |
| " The optimal daily dosage was considered to be 800-1,200 mg/body/day." | 1.27 | [Phase II study of 5'-deoxy-5-fluorouridine (5'-DFUR) in patients with malignant cancer--a multi-institutional cooperative study]. ( Abe, O; Kimura, K; Kimura, T; Kurihara, M; Nakao, I; Niitani, H; Ohta, K; Saito, T; Urushizaki, I; Yoshida, Y, 1985) |
| "1% of cases; however, it was easily reduced by decreasing the dosage or discontinuing administration of the drug." | 1.27 | [Phase II study of 5'-DFUR in gastrointestinal and breast cancer]. ( Hayashi, K; Kitamura, M; Kosaki, G; Takahashi, I; Tominaga, T, 1985) |
| "We found that this conversion in human tumors was catalyzed not by uridine phosphorylase but by thymidine phosphorylase." | 1.27 | [5'-Deoxy-5-fluorouridine enzymatic activation from the masked compound to 5-fluorouracil in human malignant tissues]. ( Hara, Y, 1984) |
| "The criteria for cancer chemotherapy of gastric cancers proposed by the Japanese Research Society for Gastric Cancer is introduced with several effective cases." | 1.27 | [Cancer chemotherapy of unresectable primary gastric cancer]. ( Kurihara, M; Taguchi, S, 1986) |
| " 5'-DFUR was administered three or four times a day at a daily dosage of 600 to 1200 mg." | 1.27 | [Clinical phase II study of 5'-DFUR for cancer of the digestive organs by a cooperative study group]. ( Gocho, Y; Ishitani, K; Kogo, Y; Kouda, K; Koyama, R; Matsuda, M; Nagai, T; Niitsu, Y; Saijo, N; Urushizaki, I, 1985) |
| "Above all, some CR cases in breast cancer indicated remarkable superiority of this drug for monotherapy." | 1.27 | [Clinical effect of 5'-deoxy-5-fluorouridine (5'-DFUR)]. ( Fujita, M; Nakano, Y; Ohota, J; Taguchi, T, 1985) |
| "In a total of 45 patients with gastric cancer, tumor tissue level of 5-fluorouracil (5-FU) was determined at 2, 4, 6, 8, and 12 hours following the oral administration of drug, using a resected stomach specimen as material." | 1.26 | Studies on the designing of chemotherapy for gastric cancer in man, based on the tumor tissue concentration of anticancer agents. ( Isobe, K; Iwase, H; Kimura, K; Kuwabara, T; Sato, A; Suga, S; Takada, T; Yokoyama, Y; Yoshida, Y, 1982) |
| "Although advanced gastrointestinal cancer is the most commonplace problem encountered by the medical oncologist, this group of diseases has proved exceedingly resistant to past chemotherapy efforts." | 1.25 | Clinical management of advanced gastrointestinal cancer. ( Moertel, CG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (26.11) | 18.7374 |
| 1990's | 61 (33.89) | 18.2507 |
| 2000's | 53 (29.44) | 29.6817 |
| 2010's | 17 (9.44) | 24.3611 |
| 2020's | 2 (1.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, F | 1 |
| Yin, J | 1 |
| Zhang, C | 1 |
| Han, M | 1 |
| Wang, X | 1 |
| Fu, S | 1 |
| Du, J | 1 |
| Zhang, H | 1 |
| Li, W | 1 |
| Bauer, M | 1 |
| Nascakova, Z | 1 |
| Mihai, AI | 1 |
| Cheng, PF | 1 |
| Levesque, MP | 1 |
| Lampart, S | 1 |
| Hurwitz, R | 1 |
| Pfannkuch, L | 1 |
| Dobrovolna, J | 1 |
| Jacobs, M | 1 |
| Bartfeld, S | 1 |
| Dohlman, A | 1 |
| Shen, X | 1 |
| Gall, AA | 1 |
| Salama, NR | 1 |
| Töpfer, A | 1 |
| Weber, A | 1 |
| Meyer, TF | 1 |
| Janscak, P | 1 |
| Müller, A | 1 |
| Moon, JH | 1 |
| Fujiwara, Y | 3 |
| Hirao, M | 2 |
| Imamura, H | 2 |
| Kimura, Y | 2 |
| Fujitani, K | 3 |
| Fujita, J | 1 |
| Tamura, S | 1 |
| Takiguchi, S | 2 |
| Yano, M | 1 |
| Mori, M | 2 |
| Doki, Y | 2 |
| Kang, YK | 2 |
| Chang, HM | 2 |
| Yook, JH | 3 |
| Ryu, MH | 2 |
| Park, I | 1 |
| Min, YJ | 1 |
| Zang, DY | 2 |
| Kim, GY | 1 |
| Yang, DH | 2 |
| Jang, SJ | 3 |
| Park, YS | 3 |
| Lee, JL | 2 |
| Kim, TW | 2 |
| Oh, ST | 1 |
| Park, BK | 1 |
| Jung, HY | 2 |
| Kim, BS | 2 |
| Yoshino, S | 1 |
| Furuya, T | 1 |
| Shimizu, R | 1 |
| Ozasa, H | 1 |
| Nishimura, T | 2 |
| Fukuda, S | 2 |
| Kawaoka, T | 1 |
| Hazama, S | 1 |
| Oka, M | 1 |
| Fukamachi, H | 1 |
| Seol, HS | 1 |
| Shimada, S | 1 |
| Funasaka, C | 1 |
| Baba, K | 1 |
| Kim, JH | 2 |
| Kim, MJ | 1 |
| Kato, K | 1 |
| Inokuchi, M | 1 |
| Kawachi, H | 1 |
| Eishi, Y | 1 |
| Kojima, K | 2 |
| Kim, WH | 1 |
| Yuasa, Y | 1 |
| Yoo, C | 1 |
| Lee, YJ | 1 |
| Kim, SG | 1 |
| Hwang, SH | 1 |
| Tsuzuki, M | 1 |
| Handa, K | 1 |
| Yamamoto, K | 1 |
| Hasegawa, A | 1 |
| Yamamoto, Y | 1 |
| Watanabe, M | 3 |
| Mizuta, S | 1 |
| Maruyama, F | 1 |
| Okamoto, M | 1 |
| Emi, N | 1 |
| Ezaki, K | 1 |
| Okabe, T | 2 |
| Ohya, T | 3 |
| Matsumoto, H | 1 |
| Tago, K | 1 |
| Totsuka, O | 2 |
| Numaga, Y | 1 |
| Higuchi, T | 1 |
| Iesato, H | 1 |
| Yokomori, T | 1 |
| Kawate, S | 3 |
| Takeyoshi, I | 4 |
| Kitajima, Y | 2 |
| Yakabe, T | 2 |
| Ohtsuka, T | 1 |
| Tanaka, M | 4 |
| Sato, S | 2 |
| Nakafusa, Y | 1 |
| Miyazaki, K | 1 |
| Takanashi, K | 1 |
| Minami, S | 1 |
| Miyajima, N | 1 |
| Hirako, T | 1 |
| Hirakawa, M | 1 |
| Koh, Y | 1 |
| Saitoh, T | 1 |
| Ueno, Y | 1 |
| Sasagawa, Y | 1 |
| Yoshikawa, T | 1 |
| Tsuburaya, A | 1 |
| Shimada, K | 2 |
| Sato, A | 4 |
| Takahashi, M | 3 |
| Koizumi, W | 6 |
| Yoshizawa, Y | 1 |
| Nabeshima, K | 1 |
| Kimura, M | 1 |
| Hataya, K | 1 |
| Kobayashi, O | 1 |
| Weinreich, J | 1 |
| Schott, S | 1 |
| Königsrainer, I | 1 |
| Zieker, D | 1 |
| Königsrainer, A | 1 |
| Schott, H | 1 |
| Nukaya, H | 1 |
| Kajino, S | 1 |
| Tokuda, H | 2 |
| Tanaka, Y | 2 |
| Hasegawa, I | 1 |
| Kato, A | 1 |
| Joh, T | 1 |
| Makita, F | 2 |
| Tanahashi, Y | 2 |
| Iwazaki, S | 2 |
| Ogawa, T | 1 |
| Tomizawa, N | 2 |
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| Nakao, I | 1 |
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| Hayashi, K | 1 |
| Takahashi, I | 1 |
| Kosaki, G | 1 |
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| Irie, K | 2 |
| Yamamoto, M | 1 |
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| Satomi, T | 1 |
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| Mitsumori, N | 1 |
| Iwamoto, K | 1 |
| Murai, R | 1 |
| Nagasaki, Y | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology[NCT03092518] | Phase 2 | 27 participants (Actual) | Interventional | 2017-06-05 | Active, not recruiting | ||
| A Phase I/II Trial of TS-1 and Oxaliplatin in Patients With Advanced Colorectal Cancer[NCT00531245] | Phase 1/Phase 2 | 77 participants (Anticipated) | Interventional | 2006-08-31 | Completed | ||
| Efficacy and Safety of Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinoma[NCT04059562] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-10-28 | Active, not recruiting | ||
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| A Phase II Study of Systemic Therapy With CPT-11 (Camptosar HCl) and Cisplatin in Patients With Advanced Gastric Cancer to be Followed by Surgical Resection and Postoperative Intraperitoneal Chemotherapy[NCT00004103] | Phase 2 | 0 participants | Interventional | 1998-07-31 | Completed | ||
| Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449] | Phase 3 | 338 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for floxuridine and Cancer of Stomach
| Article | Year |
|---|---|
Chronic myeloid leukemia following chemotherapy with 5'-deoxy-5-fluorouridine for gastric cancer.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Floxuridine; Humans; Leukemia, Myelog | 2008 |
[Chemotherapy of gastric cancer--a review of clinical trials in Japan].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Clinical Trials | 2002 |
[CHEMOTHERAPY BY PERFUSION FOR CANCER OF THE STOMACH AND COLON].
Topics: Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Colonic Neoplasms; Cyclophosphamide; Flox | 1963 |
[A case of 10-year survival after combination chemotherapy of 5'-deoxy-5-fluorouridine and cisplatin and adjuvant surgery for gastric cancer with liver metastasis].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality | 2004 |
[Current combination chemotherapy containing paclitaxel for advanced, recurrent gastric cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Drug Combin | 2004 |
[Process of making a protocol for advanced gastric cancer chemotherapy--using 5'-DFUR+CDDP as an example].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Protocols; Drug Administration S | 1993 |
[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia; | 1996 |
[A case report of gastric carcinoma with complete remission of paraaortic lymph node metastasis by 5'-DFUR and MMC administration after resection of primary tumor].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Combined Modality Therapy; Floxuridine; Gastr | 1999 |
Gastric cancer in very young adults: apropos four patients and a review of the literature.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Cis | 2000 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cyt | 1974 |
Chemotherapy of residual disease in solid tumours.
Topics: Colonic Neoplasms; Cyclophosphamide; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Lun | 1971 |
45 trials available for floxuridine and Cancer of Stomach
| Article | Year |
|---|---|
Randomized Controlled Trial of Adjuvant Chemotherapy with Fluoropyrimidines
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Ad | 2017 |
Adjuvant chemotherapy for gastric cancer: a randomised phase 3 trial of mitomycin-C plus either short-term doxifluridine or long-term doxifluridine plus cisplatin after curative D2 gastrectomy (AMC0201).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Floxurid | 2013 |
Combination phase II study of weekly paclitaxel and 5'-DFUR for unresectable or recurrent gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; | 2013 |
Enhanced efficacy of postoperative adjuvant chemotherapy in advanced gastric cancer: results from a phase 3 randomized trial (AMC0101).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Fema | 2014 |
A phase II study of doxifluridine and docetaxel combination chemotherapy for advanced or recurrent gastric cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Surv | 2009 |
A phase II study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/recurrent gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation | 2011 |
Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Dose-Response Relationship, Dr | 2011 |
The ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase in tumour tissues of patients with metastatic gastric cancer is predictive of the clinical response to 5'-deoxy-5-fluorouridine.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Enzyme-Linked Immu | 2004 |
A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; F | 2005 |
Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemother | 2005 |
Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic C | 2006 |
A phase II trial of neoadjuvant cisplatin-fluorouracil followed by postoperative intraperitoneal floxuridine-leucovorin in patients with locally advanced gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 2006 |
A clinical study of docetaxel with or without 5'DFUR as a second-line chemotherapy for advanced gastric cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Female; Floxuridine; Humans; Male; | 2007 |
Multi-center phase II study for combination therapy with paclitaxel/doxifluridine to treat advanced/recurrent gastric cancer showing resistance to S-1 (OGSG 0302).
Topics: Adenocarcinoma; Aged; Anemia; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Disease-Free | 2008 |
[Combination therapy of high dose 5'-DFUR+MMC for advanced or recurrent gastric cancer. 5'-DFUR Joint Research Group in the Osaka District for Gastric Cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Drug Administration Schedule; | 1995 |
[Effect of 5'-deoxy-5-fluorouridine (5'-DFUR) on the activity of pyrimidine nucleoside phosphorylase (pyNPase) in normal and tumor tissues of human stomach].
Topics: Antineoplastic Agents; Female; Floxuridine; Humans; Interleukin-1; Male; Middle Aged; Pentosyltransf | 1995 |
[Pharmacological study of 5'-DFUR oral administration and the clinical responses against gastrointestinal carcinoma].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Administration Sch | 1995 |
[Combination with intra-hepatic arterial infusion of low-dose cisplatin and oral administration of high-dose doxyfluridine in patients with liver metastases of gastric cancer].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administ | 1994 |
[Evaluation of combination chemotherapy for advanced gastric carcinoma as a neoadjuvant chemotherapy with CDDP, MMC, etoposide and 5'-DFUR].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Drug Admini | 1994 |
[Study of 5'-DFUR treatment as postoperative adjuvant chemotherapy for stomach and colorectal cancer. Tokai GATS Group (pilot study)].
Topics: Administration, Oral; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Diarrhea; | 1994 |
[Sequential methotrexate/5-fluorouracil therapy with 5'-deoxy-5-fluorouridine against advanced gastric cancer: comparison between bolus injection and drip infusion of 5-fluorouracil administration. Hirosaki Cooperative Study Group for Cancer Chemotherapy]
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alopecia; Anorexia; Antineoplastic Combined Ch | 1994 |
A phase II study of combination therapy with 5'-deoxy-5-fluorouridine and cisplatin in the treatment of advanced gastric cancer with primary foci.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; | 1993 |
Chronomodulated 5-day infusion of floxuridine and L-folinic acid in patients with advanced malignancies: a feasibility and tolerability study.
Topics: Adult; Aged; Antidotes; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Chronobiology Phenom | 1995 |
[Influence of intratumor administration of OK-432 on the tumor selectivity of 5'-DFUR].
Topics: Antineoplastic Agents; Floxuridine; Humans; Injections, Intralesional; Isomerism; Pentosyltransferas | 1995 |
[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia; | 1996 |
[Significance of 5'-deoxy-5-fluorouridine (5'-DFUR) administration before surgery for advanced gastric and colonic cancers--activity of pyrimidine nucleoside phosphorylase (PyNPase) and serum immunosuppressive acidic protein (IAP)].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Drug | 1996 |
Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1997 |
[Correlation between pyrimidine nucleoside phosphorylase (PyNPase)/thymidine phosphorylase/platelet-derived endothelial cell growth factor and histological prognostic factor, and influence of 5'-deoxy-5-fluorouridine (5'-DFUR) administration on PyNPase ac
Topics: Antineoplastic Agents; Drug Administration Schedule; Female; Floxuridine; Humans; Male; Middle Aged; | 1998 |
A phase II study of weekly high-dose 5-fluorouracil and leucovorin plus biweekly alternating doxorubicin and cisplatin for advanced gastric carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Resp | 1998 |
[Correlation between pyrimidine nucleoside phosphorylase (PyNPase)/platelet-derived endothelial cell growth factor and histological prognostic factor, and influences of 5'-deoxy-5-fluorouridine (5'-DFUR) administration on PyNPase levels. 5'-DFUR Joint Res
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Flox | 1998 |
[Comparative study of 5'-DFUR administration in patients with elderly cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Colonic Neoplasms; Female; Floxuridine; Humans; Male | 1998 |
[Effect of CDDP/5'-DFUR combination chemotherapy for advanced or recurrent gastric cancer].
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chil | 1998 |
Combination chemotherapy of oral 5'-deoxy-5-fluorouridine and cisplatin in advanced gastric cancer: a phase II study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug A | 1998 |
[Two regimens of combined 5'-deoxy-5-fluorouridine and cisplatin showing different dose intensities--investigation based on relative performances].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dose-Response Relationship, Drug; Drug Ad | 1999 |
A phase III randomized study comparing oral doxifluridine and oral 5-fluorouracil after curative resection of gastric cancer.
Topics: Administration, Oral; Adult; Aged; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Floxuridin | 2000 |
[Long-term outcome of preoperative chemotherapy with 5'-deoxy-5-fluorouridine (5'-DFUR) for gastric cancer].
Topics: Administration, Oral; Aged; Antineoplastic Agents; Female; Floxuridine; Follow-Up Studies; Humans; M | 2000 |
[Adjuvant chemotherapy after curative resection for gastric cancer-5'-DFUR + cisplatin vs 5'-DFUR].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Dise | 2002 |
A phase II study of doxifluridine in elderly patients with advanced gastric cancer: the Japan Clinical Oncology Group Study (JCOG 9410).
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Drug Administration Schedule; Female; Flox | 2002 |
Factors related to survival following resection for gastric carcinoma: analysis of 903 cases.
Topics: Adult; Aged; Clinical Trials as Topic; Floxuridine; Humans; Male; Middle Aged; Prognosis; Recurrence | 1977 |
Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; | 1992 |
[Requirements for the randomized trial of i.a. vs. i.v. administration to reveal the impact of hepatic arterial infusion on survival in the treatment of liver metastases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female; Floxuri | 1990 |
[Clinical trial of 5'-DFUR against various malignant tumors].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Colonic Neoplasms; Drug Adm | 1985 |
[Clinical trial of 5'-deoxy-5-fluorouridine (5'-DFUR) in advanced cancer patients].
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Administration Schedul | 1985 |
[Randomized comparison of continuous and intermittent oral administration of 5'-deoxy-5-fluorouridine in the treatment of advanced gastric cancer; a phase II trial by the Multi-institutional Cooperative Study Group].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Drug Administration Sch | 1987 |
Adrenal function in patients treated with testosterone and fluorinated pyrimidines.
Topics: 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormon | 1968 |
125 other studies available for floxuridine and Cancer of Stomach
| Article | Year |
|---|---|
Affibody-Conjugated RALA Polymers Delivering Oligomeric 5-Fluorodeoxyuridine for Targeted Therapy of HER2 Overexpressing Gastric Cancer.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biophysical Phenomena; Cell Death; Cell Line, Tumor; Dru | 2020 |
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress.
Topics: Adaptor Proteins, Signal Transducing; Bacterial Proteins; Cell Line, Tumor; DNA; DNA Damage; DNA Rep | 2020 |
CD49f(high) cells retain sphere-forming and tumor-initiating activities in human gastric tumors.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Floxuridi | 2013 |
The association between the duration of fluoropyrimidine-based adjuvant chemotherapy and survival in stage II or III gastric cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cape | 2016 |
[A case of complete response for advanced gastric cancer with liver metastasis treated with combination chemotherapy of weekly paclitaxel and doxifluridine].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Floxuridine; Humans; Liver | 2009 |
[Complete response obtained with first-line therapy as S-1, followed by second-line 5'-DFUR plus paclitaxel therapy in a patient with multiple liver and lymph node metastases from gastric cancer].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Drug Co | 2009 |
[A long term survivor of advanced gastric cancer treated with multi-drug combination chemotherapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Ant | 2009 |
Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tu | 2011 |
[Bi-weekly docetaxel and doxifluridine combination therapy in pretreated patients with unresectable and/or advanced gastric cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Female; F | 2010 |
[A case of gastric cancer with lung, Virchow and para-aortic lymph node metastases treated successfully using PTX/5'-DFUR].
Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta; Combined Modality Therapy; Fatal Outcome; Flo | 2011 |
[Improved sensitivity of gastric carcinoma cells to fluorouracil-related drugs by transfection of thymidine phosphorylase gene].
Topics: Antimetabolites, Antineoplastic; Capecitabine; Cell Line, Tumor; Deoxycytidine; Floxuridine; Fluorou | 2011 |
Postoperative intraperitoneal 5-fluoro-2'-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chem | 2012 |
Second-line chemotherapy with paclitaxel and doxifluridine after failure of S-1 in elderly patients with unresectable advanced or recurrent gastric cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; | 2011 |
Prognostic significance of miR-181b and miR-21 in gastric cancer patients treated with S-1/Oxaliplatin or Doxifluridine/Oxaliplatin.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Female; Fl | 2011 |
The effect of locoregional transarterial infusion chemotherapy on liver metastasis after gastric cancer resection.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Humans; I | 2012 |
[A case report of complete response by weekly paclitaxel and 5'-DFUR combination chemotherapy for recurrenced gastric cancer with peritoneal dissemination].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Floxuridine; Gastre | 2012 |
[A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration Schedule; Floxu | 2002 |
[A case of recurrent gastric cancer that responded dramatically to docetaxel and 5'-DFUR combination chemotherapy].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Administr | 2002 |
Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); | 2002 |
Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm | 2002 |
CHEMOTHERAPY OF METASTATIC LIVER CANCER BY PROLONGED HEPATIC-ARTERY INFUSION.
Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Chemotherapy, Cancer, Regional Perfusion; Colo | 1964 |
ACUTE GASTRITIS RESULTING FROM REGIONAL INFUSION OF AN ANTIMETABOLITE.
Topics: Adenocarcinoma; Angiography; Antimetabolites; Chemotherapy, Cancer, Regional Perfusion; Diagnosis, D | 1963 |
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neop | 1964 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; Dihydrouracil Dehydrogenase | 2004 |
[A case of advanced gastric cancer successfully treated with neoadjuvant chemotherapy of combined weekly paclitaxel and doxifluridine (5'-DFUR)].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug A | 2004 |
Comparison of intraperitoneal continuous infusion of floxuridine and bolus administration in a peritoneal gastric cancer xenograft model.
Topics: Animals; Floxuridine; Humans; Injections, Intraperitoneal; Lactic Acid; Male; Maximum Tolerated Dose | 2004 |
Therapeutic effects of novel anti-tumor reagent, apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line on human gastric carcinoma-bearing SCID mice.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Body Weight; CD57 Antigens; Chromatography, Hig | 2004 |
Doxifluridine-induced neurotoxicity with normal dihydropyrimidine dehydrogenase activity.
Topics: Aged; Antimetabolites, Antineoplastic; Biotransformation; Cerebellar Nuclei; Chemotherapy, Adjuvant; | 2004 |
S-1-induced, prolonged complete regression of lung metastasis from gastric cancer refractory to 5'-DFUR: a case report with pharmacokinetic study.
Topics: Adenocarcinoma, Mucinous; Administration, Oral; Antimetabolites, Antineoplastic; Chemotherapy, Adjuv | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; DNA Damage; DNA, Neop | 2004 |
[The association of expression and gene polymorphism of the thymidylate synthase gene with 5-fluoro-5'-deoxyuridine sensitivity in gastric cancer cell lines].
Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Floxuridine; Humans; Polymorphism, Genetic; Stoma | 2004 |
Enhancement of antitumor activity of 5'-deoxy-5-fluorouridine (Furtulon) by taxane in human gastric cancer xenografts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Cell Line, Tumor; F | 2005 |
[Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Sche | 2005 |
[Prediction and treatment of peritoneal dissemination in gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Combination | 2005 |
[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubicin; Drug Combi | 2005 |
Level of 5-fluorodeoxyuridine 5'-monophosphate in cancerous tissue in patients with gastric cancer under preoperative administration of TS-1. A preliminary study.
Topics: Adult; Aged; Antineoplastic Agents; Drug Combinations; Female; Floxuridine; Humans; Male; Middle Age | 2005 |
[A case of advanced gastric cancer with direct invasion of the transverse colon responding to paclitaxel/5'-DFUR combined therapy].
Topics: Adenocarcinoma, Scirrhous; Antineoplastic Combined Chemotherapy Protocols; Colon, Transverse; Coloni | 2005 |
[A long-term survivor with stage IV gastric cancer due to postoperative weekly paclitaxel and 5'-DFUR combination therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Combined Modality Thera | 2006 |
[Combined chemotherapy with weekly Paclitaxel and doxifluridine for advanced and recurrent gastric cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; F | 2006 |
[A case of recurrent gastric cancer effectively treated by combination chemotherapy of weekly paclitaxel and 5'- DFUR after showing resistance to weekly paclitaxel].
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Moda | 2006 |
[A case of gastric cancer with multiple liver metastases resistant to TS-1 responding to chemotherapy with paclitaxel plus doxifluridine].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat | 2006 |
[A case of advanced gastric cancer--efficacy of combination therapy of doxifluridine and weekly paclitaxel].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Combined Modality Thera | 2006 |
Unresectable gastric cancer with multiple liver metastases effectively treated with combined paclitaxel and doxifluridine chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Floxuridine; Humans; Liver Neoplasms; Male; Pa | 2006 |
[A case of recurrent gastric cancer with peritoneal dissemination responding to doxifluridine/paclitaxel combination chemotherapy as third-line treatment].
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Combined Modality Therapy; D | 2007 |
[Combination therapy with bi-weekly docetaxel and 5'-deoxy-5-fluorouridine for advanced gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Docetaxel; Drug Adm | 2007 |
Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1.
Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Antineoplastic Combine | 2007 |
Studies on the designing of chemotherapy for gastric cancer in man, based on the tumor tissue concentration of anticancer agents.
Topics: Antineoplastic Agents; Floxuridine; Fluorouracil; Gastric Mucosa; Humans; Stomach Neoplasms; Tegafur | 1982 |
Peptic ulceration with marked epithelial atypia following hepatic arterial infusion chemotherapy. A lesion initially misinterpreted as carcinoma.
Topics: Aged; Diagnostic Errors; Duodenum; Epithelium; Female; Floxuridine; Gastric Mucosa; Hepatic Artery; | 1983 |
[Phase I study of a new floxuridine derivative, 2'-deoxy-3', 5'-di-O-acetyl-5-fluoro-3-(3-methylbenzoyl)uridine (FF-705)].
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Capsules; Drug Administration Schedule; Drug Ev | 1984 |
[Phase II study of FF-705 by Clinical Cooperative Study Group].
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Capsules; Colonic Neoplasms; Drug Administratio | 1984 |
[Effects of 5'-deoxy-5-fluorouridine on human gastrointestinal and breast cancers xenografted to nude mice].
Topics: Adenocarcinoma; Administration, Oral; Animals; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Femal | 1984 |
[Measurement of 5'-deoxy-5-fluorouridine (5'-DFUR) by high-performance liquid chromatography and studies on pharmacokinetics of 5'-DFUR and 5-fluorouracil by oral and intravenous administration].
Topics: Administration, Oral; Aged; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Floxuri | 1984 |
[5'-Deoxy-5-fluorouridine enzymatic activation from the masked compound to 5-fluorouracil in human malignant tissues].
Topics: Administration, Oral; Aged; Animals; Antineoplastic Agents; Enzyme Activation; Female; Floxuridine; | 1984 |
[Combination therapy of doxifluridine, pirarubicin and cisplatin for human gastric cancers implanted in nude mice].
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cisplatin; Dox | 1995 |
[A case of advanced gastric cancer successfully treated with combination chemotherapy using THP, 5'-DFUR and CDDP, followed by surgical resection].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Drug A | 1995 |
[Study on pyrimidine nucleoside phosphorylase (PyNPase) activity in resected tissues of patients with gastric cancer].
Topics: Adult; Aged; CD4-CD8 Ratio; Female; Floxuridine; Gastrectomy; Humans; Lymphatic Metastasis; Lymphocy | 1995 |
[A successful 5'-DFUR and CDDP combination therapy for an advanced gastric cancer complicated with multiple liver metastases].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration | 1995 |
[Study of PyNPase activity in patients with gastric cancer--the association with preoperative IAP values].
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Floxuridine; Gastrectomy; Humans; Lymph N | 1995 |
Simultaneous occurrence of adenomas in stomach, duodenal bulb, and colon: disappearance of gastric and duodenal adenomas during oral administration of 5'-deoxy-5-fluorouridine.
Topics: Adenoma; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Colonic Neoplasms; Duodenal Neoplas | 1994 |
[A case of advanced gastric cancer with liver metastasis disappeared by oral administration of 5'-deoxy-5-fluorouridine after absolute non-curative operation].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Floxuridi | 1994 |
Augmentation of 5-fluoro-2'-deoxyuridine cytotoxicity by 5-phenethyl-2'-deoxyuridine in human gastric cancer cells in culture.
Topics: Carbon Radioisotopes; Deoxyuridine; DNA, Neoplasm; Drug Synergism; Floxuridine; Humans; Nucleosides; | 1994 |
[A case of cutaneous and brain metastasis of gastric carcinoma, treated effectively by chemotherapy with CDDP, MMC, etoposide and 5'-DFUR].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Ne | 1994 |
The significance of preoperative chemotherapy for early gastric carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Drug Administra | 1993 |
[A case of advanced gastric cancer with liver and lung metastasis effectively treated by combined chemo-immunotherapy of MMC, 5'-DFUR, OK-432].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Dru | 1993 |
Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine.
Topics: Antineoplastic Agents; Blotting, Northern; Cell Division; Colonic Neoplasms; Cytokines; Depression, | 1993 |
[Successful combination chemotherapy for a post-operative gastric cancer patient with multiple liver metastases and elevated CEA].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Combined Modality Th | 1996 |
[Combined chemotherapy with MMC, ADM, CDDP, etoposide (VP-16) and 5'-DFUR, (MACVD therapy) as a second-line chemotherapy for metastatic gastric cancer: three cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Floxuridi | 1996 |
[A case of nonresectable advanced gastric cancer responding to combined chemotherapy with 5'-DFUR, CDDP, and MMC].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Flox | 1996 |
[Unresectable gastric cancer followed by remarkably effective tumor disappearance and good quality of life for 10 months after CDDP/5'-DFUR combination chemotherapy--a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Cisplatin; Esoph | 1996 |
[A case of advanced gastric cancer that responded to long-term administration of low-dose 5'-DFUR].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedul | 1997 |
[Successful 5'-DFUR, CDDP and MMC combination therapy and 5'-DFUR and carboplatin combination therapy for a patient with inoperable advanced gastric cancer with peritonitis carcinomatosa].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Drug Administration Sc | 1997 |
[Combination therapy with 5'-DFUR, MMC and CDDP in patient with far advanced gastric cancer: report of a case].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; F | 1997 |
[Successful treatment of hepatic metastasis of gastric cancer with 5'-DFUR and Lentinan].
Topics: Adenocarcinoma; Aged; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Drug Adm | 1998 |
[Comparative study of 5'-deoxy-5-fluorouridine between older cancer patients versus younger cancer patients].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Colonic Neopla | 1999 |
Prediction of response to 5'-deoxy-5-fluorouridine (5'-DFUR) in patients with inoperable advanced gastric cancer by immunostaining of thymidine phosphorylase/platelet-derived endothelial cell growth factor.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Agents; Female; Floxuridine; Gene Expression Reg | 1999 |
Carcinoma of the stomach metastatic to the liver that progressed after hepatic arterial infusion of cisplatin plus 5-floxuridine, and then dramatically regressed after chemoembolization based on positive chromogranin staining.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoembolization, Therapeutic | 1999 |
[A case of gastric carcinoma treated effectively with 5'-DFUR].
Topics: Adenocarcinoma; Administration, Oral; Aged; Antineoplastic Agents; Cardia; Drug Administration Sched | 1999 |
Prolonged stable disease effects survival in patients with solid gastric tumor: analysis of phase II studies of doxifluridine.
Topics: Antimetabolites, Antineoplastic; Clinical Trials, Phase II as Topic; Disease Progression; Floxuridin | 2000 |
[Two patients with liver metastasis from gastric cancer who responded remarkably to combined therapy of 5'-DFUR and PSK].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Gastre | 2000 |
[Effectiveness of high-dose, intermittent 5'-DFUR therapy for advanced gastric cancer].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Drug Administrati | 2001 |
[Survival of 2 years and 7 months with 5'-DFUR treatment in a patient with peritoneal gastric cancer recurrence].
Topics: Aged; Antimetabolites, Antineoplastic; Drug Administration Schedule; Floxuridine; Humans; Male; Peri | 2001 |
Thymidine phosphorylase expression is useful in selecting adjuvant chemotherapy for stage III gastric cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; | 2001 |
gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.
Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Carcinoma; Carc | 2001 |
A new micromethod for the detection of HL-A antigens on cultured human tumor cells.
Topics: Adenocarcinoma; Antibody Specificity; Colonic Neoplasms; Culture Techniques; Cytotoxicity Tests, Imm | 1975 |
Clinical management of advanced gastrointestinal cancer.
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Ther | 1975 |
In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colony-Forming Units Assay; Colorecta | 1992 |
[A case report; 5'-DFUR reduced gastric cancer with multiple liver metastasis].
Topics: Adenocarcinoma; Antineoplastic Agents; Floxuridine; Humans; Liver Neoplasms; Male; Middle Aged; Stom | 1992 |
[A case of gastric cancer with recurrent bone metastases successfully treated with induced hypertension chemotherapy using cisplatin].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Bone and Bones | 1992 |
[5-fluorouracil concentration in gastroenterological tumor tissues, in adjacent normal tissues, and in serum after preoperative oral administration of 5'-deoxy-5-fluorouridine (5'-DFUR)].
Topics: Administration, Oral; Colonic Neoplasms; Floxuridine; Fluorouracil; Gallbladder Neoplasms; Humans; S | 1991 |
[5-Fluorouracil level and pyrimidine nucleoside phosphorylase activity in cancer patients after oral administration of doxifluridine (5'-DFUR)].
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Colonic Neop | 1991 |
[A study of combined chemotherapy with MMC, ADM, CDDP, etoposide (VP-16), 5'DFUR (MAC-VD therapy) in advanced cancer and local relapse of the stomach].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxoru | 1990 |
[A progressive gastric cancer in which preoperative oral chemotherapy resulted in a histopathological "Grade 2" rating].
Topics: Adenocarcinoma; Antineoplastic Agents; Combined Modality Therapy; Drug Administration Schedule; Flox | 1990 |
[The changes in tumor markers such as serum CEA, CA 19-9, TPA and CA 125 in the chemotherapy of patients with advanced gastric cancer].
Topics: Adolescent; Adult; Aged; Antigens, Tumor-Associated, Carbohydrate; Antineoplastic Combined Chemother | 1990 |
[Preoperative chemotherapy and anti-cancer effect of gastric carcinoma].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 1990 |
[A resected case of gastric carcinoma with complete remission of Virchow's node metastasis by 5'-DFUR administration].
Topics: Adenocarcinoma; Antineoplastic Agents; Combined Modality Therapy; Female; Floxuridine; Gastrectomy; | 1990 |
[A markedly effective combination therapy of 5'-DFUR and MMC in advanced gastric cancer--a case report].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Floxuridine; Humans; M | 1990 |
[A study on pre-operative administration of 5'-DFUR in carcinomas of the gastric, breast, thyroid and colon].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Colonic Neoplasms; Combined Modality Therapy; F | 1990 |
[Study on endoscopic features in responders to systemic chemotherapy in advanced gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Fema | 1990 |
[Two cases of gastrointestinal cancers with major responses to sequential methotrexate 5-FU plus 5'-DFUR].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoembryonic Antigen; Colonic Ne | 1989 |
[A study of combined chemotherapy with MMC, ADM, CDDP, VP-16 and 5'DFUR (MAC-VD) in advanced cancers of digestive organs].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coloni | 1989 |
[Anticancer treatment with a combination of antimetabolites of polyamine and pyrimidine].
Topics: Animals; DNA Replication; Drug Therapy, Combination; Eflornithine; Floxuridine; Fluorouracil; Mice; | 1985 |
[Phase II study of 5'-deoxy-5-fluorouridine (5'-DFUR) in patients with malignant cancer--a multi-institutional cooperative study].
Topics: Anorexia; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Drug Administration | 1985 |
[Phase II study of 5'-DFUR in gastrointestinal and breast cancer].
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Diarr | 1985 |
[Phase II study of 5'-DFUR (5'-deoxy-5-fluorouridine) by the Cooperative Study Group].
Topics: Administration, Oral; Adult; Aged; Anorexia; Antineoplastic Agents; Breast Neoplasms; Colonic Neopla | 1985 |
[A case of remission of metastatic gastric cancer lesions in the chest and abdominal wall by 5'-DFUR administration].
Topics: Abdominal Muscles; Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Female; Floxuridine; | 1985 |
Combined therapy of polyamine antimetabolites and antitumor drugs for human gastric cancer xenotransplanted into nude mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carcino | 1986 |
Partial purification of a thymidine phosphorylase from human gastric cancer.
Topics: Floxuridine; Humans; In Vitro Techniques; Pentosyltransferases; Stomach Neoplasms; Thymidine; Thymid | 1986 |
[Clinical trial of 5'-deoxy-5-fluorouridine in malignant tumors under cooperative study (phase II study)].
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Floxuridine; | 1986 |
[Combination chemotherapy of human gastrointestinal and breast cancer xenografts in nude mice with 5'-deoxy-5-fluorouridine and mitomycin C].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Female | 1986 |
[Cancer chemotherapy of unresectable primary gastric cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Floxuridine; Humans; Male; Stomach Neoplasms | 1986 |
[Combination chemotherapy with 3 or 4 drugs on human breast and gastrointestinal cancer xenografts in nude mice (II)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Colonic Neopla | 1987 |
Comparison of the pyrimidine nucleoside phosphorylase activity in human tumors and normal tissues.
Topics: Colonic Neoplasms; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Pentosyltransferases; Pro | 1988 |
The antiproliferative effects of fluoropyrimidine derivatives against human tumor xenografts in a subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Colorectal Neoplasms; Floxuridine; Fluor | 1988 |
[Clinical phase II study of 5'-DFUR for cancer of the digestive organs by a cooperative study group].
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Colo | 1985 |
[A case of gastric cancer in which long-term administration of 5'-deoxy-5-fluorouridine (5'-DFUR) proved effective].
Topics: Adenocarcinoma, Mucinous; Antineoplastic Agents; Female; Floxuridine; Humans; Long-Term Care; Middle | 1987 |
[Clinical phase II study of TK-117 by Cooperative Study Group. Effects on gastric cancer].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Female; Floxuridin | 1985 |
[Clinical effect of 5'-deoxy-5-fluorouridine (5'-DFUR)].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Drug Administration Schedule; Drug Ev | 1985 |
[Our experience with 5-fluoro-2-desocyuridine].
Topics: Adult; Aged; Colonic Neoplasms; Female; Floxuridine; Gallbladder Neoplasms; Humans; Liver Neoplasms; | 1968 |
The value of fluorinated pyrimidines in advanced malignancy.
Topics: Adult; Breast Neoplasms; Colonic Neoplasms; Diarrhea; Female; Floxuridine; Fluorouracil; Humans; Leu | 1968 |
Use of 5-fluorodeoxyuridine (FUDR) as an adjuvant to the surgical management of carcinoma of the stomach.
Topics: Adenocarcinoma; Adult; Aged; Floxuridine; Gastrectomy; Humans; Male; Methods; Middle Aged; Postopera | 1969 |
Chemotherapy of gastrointestinal cancer.
Topics: Antineoplastic Agents; Colonic Neoplasms; Esophageal Neoplasms; Floxuridine; Fluorouracil; Gastroint | 1972 |
Adenocarcinomas of stomach, pancreas, liver, and biliary tracts. Survival of 328 patients treated with fluoropyrimidine therapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Bile Duct Neoplasms; Evaluation Studies as Topic; Floxuridine | 1974 |
The clinical effects of prolonged intravenous infusion of 5-fluoro-2'-deoxyuridine.
Topics: Adenoma, Islet Cell; Aged; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Fl | 1965 |
Clinical evaluation of 5-bromo-5-fluoro-6-methoxy-dihydro-2'-deoxyuridine.
Topics: Adenocarcinoma; Adult; Aged; Animals; Bromodeoxyuridine; Carcinoma; Carcinoma, Hepatocellular; Carci | 1967 |