floxuridine has been researched along with Cancer of Nasopharynx in 9 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Concurrent carboplatin chemotherapy did not significantly improve the long-term survival after inductive carboplatin and floxuridine chemotherapy in locoregionally advanced nasopharyngeal carcinoma." | 5.20 | Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area. ( Cao, KJ; Guo, L; Guo, X; Hong, MH; Huang, PY; Mai, HQ; Mo, HY; Qian, CN; Wu, PH; Zeng, Q, 2015) |
| "To evaluate the benefits and risks of hepatic artery infusion (HAI) gemcitabine and floxuridine (FUDR) in patients with nasopharyngeal carcinoma liver metastases." | 3.96 | Hepatic artery infusion pump for nasopharyngeal carcinoma with liver metastasis. ( Li, G; Li, H; Peng, C; Shi, L; Zhou, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, C | 1 |
| Zhou, C | 1 |
| Li, G | 1 |
| Li, H | 1 |
| Shi, L | 1 |
| Huang, PY | 3 |
| Zeng, Q | 1 |
| Cao, KJ | 3 |
| Guo, X | 3 |
| Guo, L | 3 |
| Mo, HY | 3 |
| Wu, PH | 1 |
| Qian, CN | 1 |
| Mai, HQ | 3 |
| Hong, MH | 3 |
| Chen, LC | 2 |
| Hsueh, C | 1 |
| Tsang, NM | 2 |
| Liang, Y | 2 |
| Chang, KP | 1 |
| Hao, SP | 1 |
| Yu, JS | 1 |
| Chang, YS | 2 |
| Luo, DH | 2 |
| Qiu, F | 2 |
| Li, NW | 2 |
| Xiang, YQ | 2 |
| Chen, QY | 2 |
| Zhang, L | 2 |
| Sun, R | 2 |
| Deng, MQ | 2 |
| Zhang, F | 1 |
| Cao, SM | 2 |
| Chen, MY | 1 |
| Guo, Y | 2 |
| Fan, YY | 1 |
| Hu, W | 1 |
| Hua, YJ | 2 |
| Xie, GF | 1 |
| Chen, CC | 1 |
| OETTGEN, HF | 2 |
| CLIFFORD, P | 1 |
| CANDLER, P | 1 |
| Oberfield, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter and Prospective Clinical Trial of Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma[NCT04522050] | Phase 1 | 65 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for floxuridine and Cancer of Nasopharynx
| Article | Year |
|---|---|
Ten-year outcomes of a randomised trial for locoregionally advanced nasopharyngeal carcinoma: A single-institution experience from an endemic area.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemoradiotherapy, Ad | 2015 |
Induction-concurrent chemoradiotherapy versus induction chemotherapy and radiotherapy for locoregionally advanced nasopharyngeal carcinoma.
Topics: Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Combined Modality Therap | 2009 |
A randomized trial of induction chemotherapy plus concurrent chemoradiotherapy versus induction chemotherapy plus radiotherapy for locoregionally advanced nasopharyngeal carcinoma.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Comb | 2012 |
6 other studies available for floxuridine and Cancer of Nasopharynx
| Article | Year |
|---|---|
Hepatic artery infusion pump for nasopharyngeal carcinoma with liver metastasis.
Topics: Adult; Aged; Angiography, Digital Subtraction; Antineoplastic Combined Chemotherapy Protocols; Deoxy | 2020 |
Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Biomarkers, Pharmacological; Biomarkers, Tumor; Carcin | 2008 |
Epstein-Barr virus latent membrane protein 1 induces the chemotherapeutic target, thymidine phosphorylase, via NF-kappaB and p38 MAPK pathways.
Topics: Antimetabolites, Antineoplastic; Carcinoma; Cell Line, Tumor; Floxuridine; Humans; Nasopharyngeal Ne | 2010 |
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona | 1963 |
[REGIONAL CHEMOTHERAPY OF MALIGNANT TUMORS. I. PROLONGED INTRA-ARTERIAL INFUSION OF ANTIMETABOLITES].
Topics: Antimetabolites; Catheterization; Female; Floxuridine; Humans; Infusions, Intra-Arterial; Injections | 1964 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; | 1975 |