floxuridine has been researched along with Cancer of Cecum in 5 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The elimination half-life time for 5-FU was protracted by a factor of 2-3 compared with the direct injection of 5-FU." | 2.66 | Phase I/II tolerability/pharmacokinetic study with one-hour intravenous infusion of doxifluiridine (5'-dFUrd) 3 g/m2 VS 5 g/m2 QD x 5 per month. ( Aas, M; Flokkmann, A; Fosså, SD; Heier, M; Heintz, R; Linder-Ciccolunghi, S; Moe, B, 1986) |
| "Postoperatively cecal cancer was detected." | 2.39 | [Peritoneal dissemination of cecal cancer disappearing in a patient taking 5'-DFUR for 3 years]. ( Etoh, T; Maeda, Y; Matoba, N; Nagata, T; Niiyama, H; Yoshida, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamesa, T | 1 |
| Watanabe, Y | 1 |
| Yoshimura, K | 1 |
| Mori, N | 1 |
| Yamamoto, S | 1 |
| Hazama, S | 1 |
| Tangoku, A | 1 |
| Oka, M | 1 |
| Etoh, T | 1 |
| Yoshida, J | 1 |
| Matoba, N | 1 |
| Niiyama, H | 1 |
| Maeda, Y | 1 |
| Nagata, T | 1 |
| Zhang, ZG | 2 |
| Rustum, YM | 2 |
| Harstrick, A | 1 |
| Fosså, SD | 1 |
| Flokkmann, A | 1 |
| Heier, M | 1 |
| Aas, M | 1 |
| Moe, B | 1 |
| Heintz, R | 1 |
| Linder-Ciccolunghi, S | 1 |
1 review available for floxuridine and Cancer of Cecum
| Article | Year |
|---|---|
[Peritoneal dissemination of cecal cancer disappearing in a patient taking 5'-DFUR for 3 years].
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Cecal Neoplasms; Female; Floxuridine; Humans; Middle Ag | 1994 |
1 trial available for floxuridine and Cancer of Cecum
| Article | Year |
|---|---|
Phase I/II tolerability/pharmacokinetic study with one-hour intravenous infusion of doxifluiridine (5'-dFUrd) 3 g/m2 VS 5 g/m2 QD x 5 per month.
Topics: Adenocarcinoma; Antineoplastic Agents; Cecal Neoplasms; Colonic Neoplasms; Drug Evaluation; Drug Tol | 1986 |
3 other studies available for floxuridine and Cancer of Cecum
| Article | Year |
|---|---|
[A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoembryonic | 2004 |
Pharmacologic rationale for fluoropyrimidine-leucovorin combination: biochemical mechanisms.
Topics: Cecal Neoplasms; Drug Administration Schedule; Drug Synergism; Floxuridine; Humans; Ileal Neoplasms; | 1992 |
Mechanisms of resistance to fluoropyrimidines.
Topics: Cecal Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluoro | 1992 |