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floxuridine and Cachexia

floxuridine has been researched along with Cachexia in 8 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Research Excerpts

ExcerptRelevanceReference
"Cancer cachexia is a common paraneoplastic syndrome in patients with advanced malignancies."5.30[Doxifluridine decreases serum levels of interleukin-6 in a cancer cachexia model]. ( Arime, I; Kunisue, H; Kurebayashi, J; Shimozuma, K; Sonoo, H; Tanaka, K; Udagawa, K; Yamamoto, S; Yamamoto, Y, 1999)
"The figures in patients with breast cancer were: 1,761 days (58."3.78[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR]. ( Taguchi, T, 1996)
" The degree of synergism between docetaxel and two oral fluoropyrimidines, tegafur and 5'-deoxy-5-fluorouridine (5'-dFUrd), was investigated in the KPL-4 human breast cancer xenograft model."3.71Combined effects of docetaxel and fluoropyrimidines on tumor growth and expression of interleukin-6 and thymidine phosphorylase in breast cancer xenografts. ( Kunisue, H; Kurebayashi, J; Kurosumi, M; Otsuki, T; Sonoo, H; Tanaka, K; Yamamoto, S, 2001)
"Cancer cachexia is a common paraneoplastic syndrome in patients with advanced malignancies."1.30[Doxifluridine decreases serum levels of interleukin-6 in a cancer cachexia model]. ( Arime, I; Kunisue, H; Kurebayashi, J; Shimozuma, K; Sonoo, H; Tanaka, K; Udagawa, K; Yamamoto, S; Yamamoto, Y, 1999)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujimoto-Ouchi, K1
Tamura, S1
Mori, K1
Ishikawa, T2
Eda, H3
Tanaka, Y4
Ninomiya, Y1
Ishitsuka, H4
Taguchi, T1
Okamura, A1
Ohmura, Y1
Islam, MM1
Tagawa, M1
Horitsu, K1
Moriyama, Y1
Fujimura, S1
Yamamoto, S2
Kurebayashi, J2
Kunisue, H2
Udagawa, K1
Yamamoto, Y1
Arime, I1
Tanaka, K2
Shimozuma, K1
Sonoo, H2
Hussey, HJ1
Todorov, PT1
Field, WN1
Inagaki, N1
Tisdale, MJ1
Kurosumi, M1
Otsuki, T1
Fujimoto, K1
Tanaka, T1

Reviews

1 review available for floxuridine and Cachexia

ArticleYear
[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia;

1996

Trials

1 trial available for floxuridine and Cachexia

ArticleYear
[Survival and changes of clinical laboratory data in phase II study with 5'-DFUR].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Blood Cell Count; Breast Neoplasms; Cachexia;

1996

Other Studies

7 other studies available for floxuridine and Cachexia

ArticleYear
[Antitumor activity of various cytostatics in mice bearing murine advanced tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:15

    Topics: Animals; Antineoplastic Agents; Cachexia; Cyclophosphamide; Drug Screening Assays, Antitumor; Floxur

1993
Increased hepatic nicotinamide N-methyltransferase activity as a marker of cancer cachexia in mice bearing colon 26 adenocarcinoma.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:6

    Topics: Adenocarcinoma; Animals; Cachexia; Colonic Neoplasms; Floxuridine; Liver; Methyltransferases; Mice;

1998
[Doxifluridine decreases serum levels of interleukin-6 in a cancer cachexia model].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:10

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cachexia; Cell Division; Female; Floxuridine; Huma

1999
Effect of a fluorinated pyrimidine on cachexia and tumour growth in murine cachexia models: relationship with a proteolysis inducing factor.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Appetite Stimulants; Blood Proteins; Body

2000
Combined effects of docetaxel and fluoropyrimidines on tumor growth and expression of interleukin-6 and thymidine phosphorylase in breast cancer xenografts.
    Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Breast Neoplasms; Cachexia; Docetaxel; Drug Interactions;

2001
Anticachectic activity of 5'-deoxy-5-fluorouridine in a murine tumor cachexia model, colon 26 adenocarcinoma.
    Cancer research, 1990, Aug-01, Volume: 50, Issue:15

    Topics: Acute-Phase Proteins; Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Cachexia; C

1990
5'-Deoxy-5-fluorouridine improves cachexia by a mechanism independent of its antiproliferative action in colon 26 adenocarcinoma-bearing mice.
    Cancer chemotherapy and pharmacology, 1991, Volume: 29, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cachexia; Cell Division; Colonic Neoplasms; Drug Res

1991