floxuridine has been researched along with Bloom Syndrome in 3 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Bloom Syndrome: An autosomal recessive disorder characterized by telangiectatic ERYTHEMA of the face, photosensitivity, DWARFISM and other abnormalities, and a predisposition toward developing cancer. The Bloom syndrome gene (BLM) encodes a RecQ-like DNA helicase.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of cell fusion and deoxynucleosides (deoxyadenosine, dA; deoxyguanosine, dG; deoxycytidine, dC; thymidine, T) on sister-chromatid exchanges (SCEs) in Bloom syndrome (BS) was studied in two types of BrdU (bromodeoxyuridine)-sensitive and BrdU-resistant B-lymphoblastoid cell lines (LCLs) with respect to cellular proliferation in BrdU-labeled culture conditions." | 3.67 | Effects of cell fusion and deoxynucleosides on sister-chromatid exchanges in B-lymphoblastoid cell lines from 5 Bloom syndrome patients. ( Shiraishi, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fundia, AF | 1 |
| Gorla, NB | 1 |
| Bonduel, MM | 1 |
| Azpilicueta, O | 1 |
| Lejarraga, H | 1 |
| Muriel, FS | 1 |
| Larripa, IB | 1 |
| Tsuji, H | 1 |
| Heartlein, MW | 1 |
| Latt, SA | 1 |
| Shiraishi, Y | 1 |
3 other studies available for floxuridine and Bloom Syndrome
| Article | Year |
|---|---|
Increased expression of 5q31 fragile site in a Bloom syndrome family.
Topics: Bloom Syndrome; Caffeine; Child; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragil | 1992 |
Disparate effects of 5-bromodeoxyuridine on sister-chromatid exchanges and chromosomal aberrations in Bloom syndrome fibroblasts.
Topics: Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Deoxycytidine; Fibroblas | 1988 |
Effects of cell fusion and deoxynucleosides on sister-chromatid exchanges in B-lymphoblastoid cell lines from 5 Bloom syndrome patients.
Topics: B-Lymphocytes; Bloom Syndrome; Bromodeoxyuridine; Cell Division; Cell Fusion; Deoxyribonucleosides; | 1988 |