floxuridine has been researched along with Atypical Lipomatous Tumor in 2 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Growth inhibition assays indicated that the IC50 values for methotrexate (MTX) and 5-fluorodeoxyuridine (FdUrd) in HS-18, a liposarcoma cell line lacking retinoblastoma protein (pRB), and SaOS-2, an osteosarcoma cell line with a truncated and nonfunctional pRB, were 10- to 12-fold and 4- to 11-fold higher, respectively, than for the HT-1080 (fibrosarcoma) cell line, which has wild-type pRB." | 3.69 | Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. ( Almasan, A; Banerjee, D; Bertino, JR; Fan, J; Hochhauser, D; Kelly, R; Li, W; Wahl, GM; Yin, Y; Zielinski, Z, 1995) |
| "There were seven malignant fibrous histiocytomas, four liposarcomas, two fibrosarcomas, one leiomyosarcoma, and one rhabdomyosarcoma; 73% were grade III." | 1.28 | Intraarterial chemotherapy with limb-sparing resection of large soft-tissue sarcomas of the extremities. ( Bonn, J; Gardiner, GA; Lackman, RD; Shapiro, MJ; Soulen, MC; Sullivan, KL; Weiss, AJ; Weissmann, JR, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, W | 1 |
| Fan, J | 1 |
| Hochhauser, D | 1 |
| Banerjee, D | 1 |
| Zielinski, Z | 1 |
| Almasan, A | 1 |
| Yin, Y | 1 |
| Kelly, R | 1 |
| Wahl, GM | 1 |
| Bertino, JR | 1 |
| Soulen, MC | 1 |
| Weissmann, JR | 1 |
| Sullivan, KL | 1 |
| Lackman, RD | 1 |
| Shapiro, MJ | 1 |
| Bonn, J | 1 |
| Weiss, AJ | 1 |
| Gardiner, GA | 1 |
2 other studies available for floxuridine and Atypical Lipomatous Tumor
| Article | Year |
|---|---|
Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Base Sequence; Bone Neoplasms; Cell Division | 1995 |
Intraarterial chemotherapy with limb-sparing resection of large soft-tissue sarcomas of the extremities.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D | 1992 |