floxuridine has been researched along with Ascites in 5 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
Ascites: Accumulation or retention of free fluid within the peritoneal cavity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The efficacy of weekly paclitaxel in combination with doxifluridine (5'-DFUR) in gastric cancer patients with malignant ascites was evaluated." | 9.15 | Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites. ( Ishikawa, H; Iwazaki, S; Izumi, M; Kakinuma, S; Kamoshita, N; Kawate, S; Kobayashi, I; Kobayashi, J; Makita, F; Nakagami, K; Ohya, T; Okabe, T; Sakamoto, I; Sato, Y; Sunose, Y; Takeyoshi, I; Tanahashi, Y; Tomizawa, N; Yamada, T; Yoshinari, D, 2011) |
| "Gemcitabine (dFdC) is a prodrug that undergoes metabolism by cytidine deaminase to form an inactive metabolite, 2',2'-difluorodeoxyuridine (dFdU)." | 5.31 | Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites. ( Delauter, BJ; Egorin, MJ; Plunkett, W; Ramanathan, RK; Stover, LL; Zamboni, WC; Zuhowski, EG, 2000) |
| " The efficacy of weekly paclitaxel in combination with doxifluridine (5'-DFUR) in gastric cancer patients with malignant ascites was evaluated." | 5.15 | Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites. ( Ishikawa, H; Iwazaki, S; Izumi, M; Kakinuma, S; Kamoshita, N; Kawate, S; Kobayashi, I; Kobayashi, J; Makita, F; Nakagami, K; Ohya, T; Okabe, T; Sakamoto, I; Sato, Y; Sunose, Y; Takeyoshi, I; Tanahashi, Y; Tomizawa, N; Yamada, T; Yoshinari, D, 2011) |
| "Gemcitabine (dFdC) is a prodrug that undergoes metabolism by cytidine deaminase to form an inactive metabolite, 2',2'-difluorodeoxyuridine (dFdU)." | 1.31 | Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites. ( Delauter, BJ; Egorin, MJ; Plunkett, W; Ramanathan, RK; Stover, LL; Zamboni, WC; Zuhowski, EG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takeyoshi, I | 1 |
| Makita, F | 1 |
| Iwazaki, S | 1 |
| Ishikawa, H | 1 |
| Kakinuma, S | 1 |
| Sato, Y | 1 |
| Ohya, T | 1 |
| Nakagami, K | 1 |
| Tomizawa, N | 1 |
| Izumi, M | 1 |
| Kobayashi, I | 1 |
| Tanahashi, Y | 1 |
| Kobayashi, J | 1 |
| Kamoshita, N | 1 |
| Kawate, S | 1 |
| Sunose, Y | 1 |
| Sakamoto, I | 1 |
| Yoshinari, D | 1 |
| Yamada, T | 1 |
| Okabe, T | 1 |
| MARUYAMA, Y | 1 |
| SILINI, G | 1 |
| KAPLAN, HS | 1 |
| HEIDELBERGER, C | 2 |
| BOOHAR, J | 1 |
| BIRNIE, GD | 1 |
| REYES, P | 1 |
| Delauter, BJ | 1 |
| Ramanathan, RK | 1 |
| Egorin, MJ | 1 |
| Stover, LL | 1 |
| Zuhowski, EG | 1 |
| Plunkett, W | 1 |
| Zamboni, WC | 1 |
1 trial available for floxuridine and Ascites
| Article | Year |
|---|---|
Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Dose-Response Relationship, Dr | 2011 |
4 other studies available for floxuridine and Ascites
| Article | Year |
|---|---|
STUDIES OF THE LSA ASCITES LYMPHOMA OF C57B1 MICE. II. RADIOSENSITIZATION IN VIVO WITH 5-BROMODEOXYCYTIDINE AND COMBINED 5-FLUORODEOXYURIDINE AND 5-BROMODEOXYCYTIDINE.
Topics: Ascites; Bromodeoxycytidine; DNA; DNA, Neoplasm; Floxuridine; Lymphoma; Mice; Neoplasms; Neoplasms, | 1963 |
FLUORINATED PYRIMIDINES. XXII. EFFECTS OF VARIOUS COMPOUNDS ON THE INCORPORATION OF (14C)FORMATE INTO DNA THYMINE IN SUSPENSIONS OF EHRLICH ASCITES CELLS.
Topics: Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; | 1964 |
FLUORINATED PYRIMIDINES. XXV. THE INHIBITION OF THYMIDYLATE SYNTHETASE FROM EHRLICH ASCITES CARCINOMA CELLS BY PYRIMIDINE ANALOGS.
Topics: Adenosine Triphosphate; Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Enzyme Inhibitors; Fl | 1965 |
Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites.
Topics: Abdominal Pain; Adenocarcinoma; Antimetabolites, Antineoplastic; Ascites; Catheters, Indwelling; Chr | 2000 |