floxuridine has been researched along with Abnormalities, Sex Chromosome in 15 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The main clinical features are mental retardation, typical facial dysmorphism and macroorchidism." | 2.37 | [Mental retardation linked to fragility of chromosome X: current knowledge]. ( Auger, M; Giraud, F; Mattei, JF; Mattei, MG, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mixon, JC | 1 |
| Dev, VG | 1 |
| Hecht, F | 1 |
| Jacky, PB | 2 |
| Sutherland, GR | 3 |
| Nielsen, KB | 1 |
| Tommerup, N | 1 |
| Dyggve, HV | 1 |
| Schou, C | 1 |
| Brookwell, R | 1 |
| Daniel, A | 1 |
| Turner, G | 1 |
| Fishburn, J | 1 |
| Glover, TW | 2 |
| Howard-Peebles, PN | 1 |
| Gardiner, GB | 1 |
| Wenger, SL | 1 |
| Steele, MW | 1 |
| Cantú, ES | 1 |
| Jacobs, PA | 1 |
| Mattei, JF | 1 |
| Mattei, MG | 1 |
| Auger, M | 1 |
| Giraud, F | 1 |
| Duncan, AM | 1 |
| Baker, E | 1 |
| Purvis-Smith, S | 1 |
| Hockey, A | 1 |
| Krumins, E | 1 |
| Eichenbaum, SZ | 1 |
| Vandamme, B | 1 |
| Liebaers, I | 1 |
| Hens, L | 1 |
| Bernheim, JL | 1 |
| Roobol, C | 1 |
| Wang, JC | 1 |
| Beardsley, GP | 1 |
| Erbe, RW | 1 |
| Priest, JH | 1 |
2 reviews available for floxuridine and Abnormalities, Sex Chromosome
| Article | Year |
|---|---|
The fragile X chromosome: current methods.
Topics: Cells, Cultured; Chromosome Fragility; Chromosome Mapping; Female; Fibroblasts; Floxuridine; Folic A | 1982 |
[Mental retardation linked to fragility of chromosome X: current knowledge].
Topics: Bromodeoxyuridine; Child; Chromosome Banding; Ear, External; Face; Floxuridine; Folic Acid; Fragile | 1984 |
13 other studies available for floxuridine and Abnormalities, Sex Chromosome
| Article | Year |
|---|---|
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine.
Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X | 1983 |
Macroorchidism and fragile X in mentally retarded males. Clinical, cytogenetic, and some hormonal investigations in mentally retarded males, including two with the fragile site at Xq28, fra(X)(q28).
Topics: Adult; Aged; Birth Weight; Body Height; Body Weight; Chromosome Banding; Chromosome Mapping; Electro | 1982 |
The fragile X(q27) form of X-linked mental retardation: FUdR as an inducing agent for fra(X)(q27) expression in lymphocytes, fibroblasts, and amniocytes.
Topics: Cells, Cultured; Female; Floxuridine; Fragile X Syndrome; Humans; Lymphocytes; Male; Pedigree; Pheno | 1982 |
The combined effects of FUdR addition and methionine depletion on the X-chromosome fragile site.
Topics: Cells, Cultured; Culture Media; Female; Floxuridine; Fragile X Syndrome; Gene Expression Regulation; | 1983 |
Thymidylate synthetase inhibitors and fragile site expression in lymphocytes.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Culture Media; Deoxycytidine; Female; F | 1983 |
In vitro reversal of fragile-X expression by exogenous thymidine.
Topics: Culture Media; Floxuridine; Fragile X Syndrome; Humans; In Vitro Techniques; Lymphocytes; Male; Sex | 1984 |
Fragile (X) expression: relationship to the cell cycle.
Topics: Base Sequence; Bromodeoxyuridine; Cell Cycle; Chromosome Banding; Floxuridine; Fragile X Syndrome; H | 1984 |
FUdR induction of the X chromosome fragile site: evidence for the mechanism of folic acid and thymidine inhibition.
Topics: Cells, Cultured; DNA; Female; Floxuridine; Folic Acid; Humans; Intellectual Disability; Lymphocytes; | 1981 |
Enhanced sensitivity of lymphoblastoid cells from individuals carrying the mutation for the fragile X syndrome to the clastogenic effects of FUdR.
Topics: Cell Nucleus; Cells, Cultured; Chromosomes; Female; Floxuridine; Folic Acid; Fragile X Syndrome; Gen | 1986 |
Prenatal diagnosis of the fragile X using thymidine induction.
Topics: Adult; Amniocentesis; Australia; Chorionic Villi; Female; Floxuridine; Fragile X Syndrome; Humans; M | 1987 |
The role of fluorinated pyrimidine analogues in the induction of the in vitro expression of the fragile X chromosome.
Topics: Base Composition; Cell Division; Cells, Cultured; Deoxycytidine; DNA; DNA Damage; Floxuridine; Fragi | 1988 |
Antifolate-induced misincorporation of deoxyuridine monophosphate into DNA by cells from patients with the fragile X syndrome.
Topics: Cells, Cultured; Deoxyuracil Nucleotides; DNA; DNA Glycosylases; Floxuridine; Folic Acid Antagonists | 1985 |
The replication of human heterochromatin in serial culture.
Topics: Autoradiography; DNA Replication; Female; Floxuridine; Heterochromatin; Humans; In Vitro Techniques; | 1968 |