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floxuridine and Abnormalities, Drug-Induced

floxuridine has been researched along with Abnormalities, Drug-Induced in 18 studies

Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's3 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chahoud, I1
Talsness, CE1
Walter, A1
Grote, K1
Ritter, EJ1
Scott, WJ1
Wilson, JG1
Mathinos, PR1
Randall, JL1
Amwayi, PJ1
Otiang'a-Owiti, GE1
Nolan, RS1
Schwartz, G1
Farquharson, S1
Hootnick, DR1
Levinsohn, EM1
Miller, M1
Manz, LA1
Packard, DS1
Nagao, T1
Kuwagata, M1
Saito, Y1
Forsthoefel, PF1
Williams, ML1
Langman, J2
Cardell, EL1
Crowley, KK1
Geelen, JA1
Ferguson, MW1
Khan, KM1
Hall, BK1
Bro-Rasmussen, F3
Jensen, B3
Sorensen, AH2
Kury, G1
Craig, JM1
Hansen, OM1
Ostergaard, AH1
Omori, K1
Williams, JP1
Kleinbrecht, J1

Other Studies

18 other studies available for floxuridine and Abnormalities, Drug-Induced

ArticleYear
Postnatal investigation of prenatally induced effects on the vertebral column of rats reduces the uncertainty of classification of anomalies.
    Reproductive toxicology (Elmsford, N.Y.), 2015, Volume: 58

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Female; Floxuridine; Gestational Age; Male; Pregn

2015
Potentiative interactions between caffeine and various teratogenic agents.
    Teratology, 1982, Volume: 25, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Caffeine; Cycloheximide; Dactinomycin; Dose-Res

1982
Use of biometric embryonic growth parameters as indicator of exposure to a teratogen.
    East African medical journal, 1997, Volume: 74, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Anthropometry; Embryonic and Fetal Development; Female; Floxur

1997
Hematomas and limb skeletal malformations in chicken embryos following exposure to 5-fluoro-2-deoxyuridine.
    Biomedical and environmental sciences : BES, 1998, Volume: 11, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites, Antineoplastic; Blister; Chick Embryo; Floxur

1998
Effects of prenatal exposure to 5-fluoro-2'-deoxyuridine on developing central nervous system and reproductive function in male offspring of mice.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites, Antineoplastic; Brain; DNA Fragmentation; Dos

1998
The effects of 5-fluorouracil and 5-fluorodeoxyuridine used alone and in combination with normal nucleic acid precursors on development of mice in lines selected for low and high expression of Strong's luxoid gene.
    Teratology, 1975, Volume: 11, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cell Survival; Drug Synergism; Female; Fetal Deat

1975
Cell degeneration and recovery of the fetal mammalian brain after a chemical insult.
    Teratology, 1977, Volume: 16, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Cell Movement; Cell Survival; DNA Replication; Female;

1977
Repair mechanism in the embryonic spinal cord after a chemical insult.
    Teratology, 1978, Volume: 17, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Epithelial Cells; Floxuridine; Mitosis; Spinal C

1978
The teratogenic effects of 5-fluoro-2-desoxyuridine (F.U.D.R.) on the Wistar rat fetus with particular reference to cleft palate.
    Journal of anatomy, 1978, Volume: 126, Issue:Pt 1

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Central Nervous System; Cleft Palate; Fetus; Flox

1978
Protective role of compensatory growth in the development of mammalian inner ear.
    JPMA. The Journal of the Pakistan Medical Association, 1986, Volume: 36, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Ear, Inner; Female; Floxuridine; Pregnancy; Rats; Rats, Inbred

1986
Development of the mandibular skeleton in the embryonic chick as evaluated using the DNA-inhibiting agent 5-fluoro-2'-deoxyuridine.
    Journal of craniofacial genetics and developmental biology, 1987, Volume: 7, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cell Differentiation; Cell Division; Chick Embryo;

1987
"Spontaneous" amputations.
    Lancet (London, England), 1972, Apr-22, Volume: 1, Issue:7756

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amputation, Surgical; Animals; Female; Floxuridi

1972
Congenital malformations produced in chickens by fluorinated pyrimidines.
    Archives of pathology, 1966, Volume: 81, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Chick Embryo; Floxuridine; Fluorouracil; Pyri

1966
Fluorodeoxyuridine-induced malformations in mice. Studies on the early stages of teratogenesis.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cleft Palate; Clubfoot; Encephalocele; Femal

1971
Teratogenic effects of 5-fluoro-2'-deoxyuridine in pregnant mice.
    Teratology, 1972, Volume: 5, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Floxuridine; Liver; Mice; Nucleic A

1972
Congenital meromelia or "spontaneous amputations". Experimental studies on mice.
    Acta orthopaedica Scandinavica, 1972, Volume: 43, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Animals, Newborn; Ectromelia; Female;

1972
Incorporation of thymidine after administration of fluorouracil and fluorouridine to adult and embryo mice.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, Drug; E

1971
The embryotoxic effects of 5-fluoro-2'-deoxyuridine in mice.
    Teratology, 1970, Volume: 3, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetus; Floxuridine;

1970