floxuridine has been researched along with Abnormalities, Autosome in 52 studies
Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
floxuridine : A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings suggest that chromosomal abnormalities in childhood malignancies cannot generally be explained by the presence of FdU- or FdU plus caffeine-induced fragile sites." | 1.28 | Relationship between chemical-induced fragile sites and chromosomal breakpoints in malignant cells in children. ( Crist, WM; Douglass, EC; Lewis, S; Raimondi, SC; Ribeiro, RC; Valentine, M; Williams, DL, 1992) |
| "The frequencies of chromosome aberrations and development of the bromodeoxyuridine (BrdU)-sensitive fragile site were studied in vitro in Chinese hamster kidney and bone marrow cells and in vivo in Chinese hamster bone marrow cells." | 1.27 | An in vitro and in vivo study of a BrdU-sensitive fragile site in the Chinese hamster. ( Lin, MS; Marchese, CA; Takabayashi, T; Wilson, MG, 1984) |
| "Caffeine did not enhance the expression of the fra(X) in the PBLC or in the three LCL from fra(X) expressing individuals nor did it elicit fra(X) expression in LCL from a non-expressing obligate-carrier female and a transmitting male." | 1.27 | The effect of caffeine on fragile X expression. ( Abruzzo, MA; Jacobs, PA; Mayer, M; Pettay, D, 1986) |
| "FudR barely affected the frequency of chromosomal aberrations." | 1.26 | [Formation of chromosome aberrations in human lymphocytes to the action of 5-fluorodeoxyuridine used separately and in combination with gamma irradiation: changes in the effect in the course of the mitotic cycle]. ( Izmaĭlova, NN; Luchnik, NV; Poriadkova, NA, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (84.62) | 18.7374 |
| 1990's | 6 (11.54) | 18.2507 |
| 2000's | 2 (3.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, A | 1 |
| Abdullah, M | 1 |
| Babar, ME | 1 |
| Javed, K | 1 |
| Nadeem, A | 1 |
| Luchnik, NV | 2 |
| KIHLMAN, BA | 3 |
| NATARAJAN, AT | 3 |
| RAO, RN | 1 |
| Barclay, BJ | 1 |
| Kunz, BA | 1 |
| Little, JG | 1 |
| Haynes, RH | 1 |
| Makedonov, GP | 1 |
| Tarasov, VA | 1 |
| Lin, MS | 1 |
| Takabayashi, T | 1 |
| Wilson, MG | 1 |
| Marchese, CA | 1 |
| Barbi, G | 2 |
| Steinbach, P | 2 |
| Vogel, W | 2 |
| Korotkov, EV | 1 |
| Bokhon'ko, AI | 1 |
| Petrov, OE | 1 |
| Akif'ev, AP | 2 |
| Sono, A | 1 |
| Sakaguchi, K | 1 |
| Yajima, N | 1 |
| Kondo, K | 1 |
| Morita, K | 1 |
| Poriadkova, NA | 1 |
| Izmaĭlova, NN | 1 |
| Yang, MY | 1 |
| Long, SE | 1 |
| Güven, GS | 1 |
| Hacihanefioğlu, S | 1 |
| Cenani, A | 1 |
| Dutrillaux, B | 1 |
| Aurias, A | 1 |
| Fosse, AM | 1 |
| Bauknecht, T | 1 |
| Bayer, U | 1 |
| Wild, D | 1 |
| Volgareva, GM | 1 |
| Sokova, OI | 1 |
| Pogosiants, EE | 1 |
| Traut, H | 1 |
| Fundia, AF | 1 |
| Gorla, NB | 1 |
| Bonduel, MM | 1 |
| Azpilicueta, O | 1 |
| Lejarraga, H | 1 |
| Muriel, FS | 1 |
| Larripa, IB | 1 |
| Dewald, GW | 1 |
| Buckley, DD | 1 |
| Spurbeck, JL | 1 |
| Jalal, SM | 1 |
| Ribeiro, RC | 1 |
| Douglass, EC | 1 |
| Williams, DL | 1 |
| Raimondi, SC | 1 |
| Valentine, M | 1 |
| Lewis, S | 1 |
| Crist, WM | 1 |
| Zaslav, AL | 1 |
| Brown, WT | 1 |
| Mateos, S | 2 |
| Piñero, J | 2 |
| Ortiz, T | 2 |
| Cortés, F | 2 |
| Beliaev, IIa | 1 |
| Semakin, AB | 1 |
| Grigorova, NV | 1 |
| Smeets, DF | 1 |
| Scheres, JM | 1 |
| Hustinx, TW | 1 |
| Abruzzo, MA | 1 |
| Pettay, D | 1 |
| Mayer, M | 1 |
| Jacobs, PA | 1 |
| Tsuji, H | 1 |
| Heartlein, MW | 1 |
| Latt, SA | 1 |
| Przylepa, KA | 1 |
| Wenger, SL | 1 |
| Djalali, M | 1 |
| Hampel, KE | 2 |
| Gerhartz, H | 1 |
| Fahmy, OG | 1 |
| Fahmy, MJ | 1 |
| De Vrye, CE | 1 |
| Hartley, B | 1 |
| Westphal, F | 1 |
| Hagen, U | 1 |
| Rushton, PS | 1 |
| Ockey, CH | 2 |
| Bos, M | 1 |
| Scharloo, W | 1 |
| Bijlsma, R | 1 |
| de Boer, IM | 1 |
| den Hollander, J | 1 |
| Kvelland, I | 1 |
| Vig, BK | 1 |
| Honda, M | 1 |
| Uchida, H | 1 |
| Hägele, K | 1 |
| Stopik, D | 1 |
| Knight, LA | 1 |
| Luzzatti, L | 1 |
| Akifjev, AP | 1 |
| Aingorn, ED | 1 |
| Painter, RB | 1 |
| Smith, RH | 1 |
| Hoffmann, GR | 1 |
| Malling, HV | 1 |
| Mitchell, TJ | 1 |
| Bender, MA | 1 |
| Griggs, HG | 1 |
| Bedford, JS | 1 |
| Kulinich, AV | 1 |
| Ahnström, G | 1 |
3 reviews available for floxuridine and Abnormalities, Autosome
| Article | Year |
|---|---|
Cytogenetic guidelines for fragile X studies tested in routine practice.
Topics: Adolescent; Adult; Cell Count; Cells, Cultured; Child; Child, Preschool; Chromosome Aberrations; Cul | 1992 |
The action of ultraviolet light on mammalian cells.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Chlorides; Chromosome Aberrations; Crice | 1970 |
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; | 1974 |
49 other studies available for floxuridine and Abnormalities, Autosome
| Article | Year |
|---|---|
Expression and identification of folate-sensitive fragile sites in British Suffolk sheep (Ovis aries).
Topics: Animals; Cell Count; Chromosome Aberrations; Chromosome Banding; Chromosome Fragile Sites; Chromosom | 2008 |
[Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes].
Topics: 2,4-Dinitrophenol; Adenosine Diphosphate; Chromosome Aberrations; DNA Repair; Floxuridine; Genetic V | 2002 |
DEOXYADENOSINE AS AN INDUCER OF CHROMOSOMAL ABERRATIONS IN VICIA FABA.
Topics: Chromosome Aberrations; Deoxyadenosines; DNA; Floxuridine; Nucleotides; Plants; Research; Thymidine; | 1963 |
CHROMOSOME BREAKAGE INDUCED BY FLUORINATED THYMIDINE IN SECONDARY ROOTS OF VICIA FABA.
Topics: Cell Division; Chromosome Aberrations; Chromosome Breakage; Enzyme Inhibitors; Floxuridine; Pharmaco | 1965 |
Genetic and biochemical consequences of thymidylate stress.
Topics: Chromosome Aberrations; DNA Repair; DNA, Fungal; DNA, Mitochondrial; Ethyl Methanesulfonate; Floxuri | 1982 |
[Directed modification of the damaged DNA region in inducing structural chromosomal mutations].
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Rep | 1982 |
An in vitro and in vivo study of a BrdU-sensitive fragile site in the Chinese hamster.
Topics: Animals; Bone Marrow; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Chromosome Banding | 1984 |
Potentiation of chromosomal alterations by inhibitors of DNA repair.
Topics: Animals; Anti-Bacterial Agents; Chromatids; Chromosome Aberrations; Deoxyadenosines; DNA Repair; Flo | 1984 |
Nonrandom distribution of methotrexate-induced aberrations on human chromosomes. Detection of further folic acid sensitive fragile sites.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fr | 1984 |
[Noninduced local DNA synthesis in the G1 phase and its relationship to chromosomal mutagenesis].
Topics: Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; DNA; Floxuridine; Humans; L | 1980 |
Inhibition of protein synthesis antagonizes induction of sister-chromatid exchanges by exogenous agents.
Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Crossing Over | 1981 |
Reverse mutation tests in Salmonella typhimurium and chromosomal aberration tests in mammalian cells in culture on fluorinated pyrimidine derivatives.
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Floxuridine; Fluorouracil; Mutag | 1981 |
[Formation of chromosome aberrations in human lymphocytes to the action of 5-fluorodeoxyuridine used separately and in combination with gamma irradiation: changes in the effect in the course of the mitotic cycle].
Topics: Cells, Cultured; Chromosome Aberrations; Floxuridine; Gamma Rays; Humans; Interphase; Lymphocytes; M | 1981 |
Folate sensitive common fragile sites in chromosomes of the domestic pig (Sus scrofa).
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosome Fragile Sites; Ch | 1993 |
Expression of aphidicolin, FUdR and caffeine-induced fragile sites in lymphocytes of healthy Turkish individuals.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aphidicolin; Caffeine; Cells, Cultured; Chi | 1999 |
[Differentiation of the mechanisms inducing segmentation and asymetry of chromatids after treatment with 5-bromodeoxyuridine].
Topics: Bromodeoxyuridine; Chromatin; Chromosome Aberrations; Chromosomes; Floxuridine; Humans; Lymphocytes; | 1976 |
Comparative in vivo mutagenicity testing by SCE and micronucleus induction in mouse bone marrow.
Topics: Animals; Bromodeoxyuridine; Chromatids; Chromosome Aberrations; Crossing Over, Genetic; Cyclophospha | 1977 |
[Mechanism of the chromosome damaging effect of ftorafur].
Topics: Animals; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Floxuridine; Fluorouracil; Mito | 1977 |
The induction of X-chromosomal aneuploidy by 5-fluorodeoxyuridine (FUdR) fed to Drosophila melanogaster females.
Topics: Aneuploidy; Animals; Chromosome Aberrations; Chromosomes; Drosophila melanogaster; Female; Floxuridi | 1978 |
Increased expression of 5q31 fragile site in a Bloom syndrome family.
Topics: Bloom Syndrome; Caffeine; Child; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragil | 1992 |
Relationship between chemical-induced fragile sites and chromosomal breakpoints in malignant cells in children.
Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Chromosome Aberrations; Chromosome Fragile Sit | 1992 |
Simultaneous expression of the rare and common fragile sites on the X chromosome.
Topics: Aphidicolin; Chromosome Aberrations; Chromosome Banding; Ethanol; Female; Floxuridine; Fragile X Syn | 1991 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxu | 1989 |
[Reproduction in the second nuclear cycle of chromosome aberrations induced in the G2 phase of Crepis capillaris cells by gamma rays, 5-fluoro-2-deoxyuridine and their combined action].
Topics: Chromosome Aberrations; Floxuridine; Gamma Rays; Interphase; Mitosis; Mutation; Plant Cells; Plants | 1985 |
The most common fragile site in man is 3p14.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chromosome Aberrations; Chromosome Banding; Chromo | 1986 |
The effect of caffeine on fragile X expression.
Topics: Caffeine; Cells, Cultured; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; F | 1986 |
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replica | 1987 |
Disparate effects of 5-bromodeoxyuridine on sister-chromatid exchanges and chromosomal aberrations in Bloom syndrome fibroblasts.
Topics: Bloom Syndrome; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Deoxycytidine; Fibroblas | 1988 |
Chromosome breaks and fragile sites in leukemic bone marrow cells.
Topics: Adolescent; Aged; Bone Marrow; Caffeine; Cells, Cultured; Child; Child, Preschool; Chromosome Aberra | 1988 |
Folic acid sensitive fragile sites are not limited to the human karyotype. Demonstration of nonrandom gaps and breaks in the Persian vole Ellobius lutescens Th. inducible by methotrexate, fluorodeoxyuridine, and aphidicolin.
Topics: Animals; Aphidicolin; Arvicolinae; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Frag | 1985 |
Action of 5-fluorodeoxyuridine on human chromosomes.
Topics: Chromosome Aberrations; Chromosome Disorders; Chromosomes; Floxuridine; Humans; In Vitro Techniques; | 1965 |
The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Cytarabin | 1966 |
Hydroxyurea: effect on Cicia chromosomes previously exposed to x-rays or to radiomimetic chemicals.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antitubercular Agents; Caffeine; Chromosome Aber | 1967 |
[Radiation protection and radiation sensitization in chromosomes of lymphatic cells].
Topics: Animals; Chromosome Aberrations; Chromosomes; Cysteamine; Floxuridine; Male; Mice; Radiation Injurie | 1967 |
The effects of 5-fluorodeoxyuridine on radiation-induced chromatid aberrations in Tradescantia microspores.
Topics: Chromosome Aberrations; Floxuridine; Plants; Radiation Effects; Spores | 1969 |
Human chromosome identification and the pattern of DNA replication in fibroblasts from an XXY male. A quantitative autoradiographic study of early and late synthesis.
Topics: Autoradiography; Chromosome Aberrations; Chromosomes; Chromosomes, Human, 1-3; Chromosomes, Human, 1 | 1969 |
Induction of morphological aberrations by enzyme inhibition in Drosophila melanogaster.
Topics: Aminopterin; Animals; Chromosome Aberrations; Chromosomes; Drosophila; Female; Floxuridine; Ligases; | 1969 |
The effect of homozygous deletions upon heterozygote formation in bacteriophage T4D.
Topics: Chromosome Aberrations; Coliphages; DNA, Viral; Floxuridine; Heterozygote; Homozygote | 1969 |
Human chromosome identification and the pattern of DNA replication in fibroblasts from an XXY male. A quantitative autoradiographic study of early and late synthesis.
Topics: Autoradiography; Chromosome Aberrations; Chromosomes; Chromosomes, Human, 1-3; Chromosomes, Human, 1 | 1969 |
Alterations in the pattern of daunomycin-induced chromosomal aberrations by inhibitors of protein and DNA synthesis.
Topics: Chromatids; Chromosome Aberrations; Chromosomes; Crossing Over, Genetic; Culture Media; Daunorubicin | 1970 |
Genetic recombination between closely linked markers of bacteriophage T4. I. A dual mechanism for recombinant formation.
Topics: Chromosome Aberrations; Coliphages; Floxuridine; Genetics, Microbial; Models, Biological; Radiation | 1969 |
[Effect of FUdR on the structure of polytene chromosomes and the relation of DNA replication and breakage frequency of bands].
Topics: Animals; Autoradiography; Chromosome Aberrations; Chromosome Mapping; Chromosomes; Diptera; DNA; DNA | 1971 |
Intrachromosomal distribution of spontaneous and induced breaks in human lymphocytes.
Topics: Alkylating Agents; Benz(a)Anthracenes; Carcinogens; Cells, Cultured; Chromatids; Chromosome Aberrati | 1971 |
Replication pattern of the X and Y chromosomes in partially synchronized human lymphocyte cultures.
Topics: Autoradiography; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; DNA; DNA Replication | 1973 |
DNA synthesis related to genome activation in human lymphocytes cultured in vitro.
Topics: Autoradiography; Chromosome Aberrations; Chromosomes; Colchicine; Dactinomycin; DNA; Female; Floxuri | 1972 |
Induction of lethality in first meiotic oocytes of Habrobracon with mitomycin C and 5-fluorodeoxyuridine.
Topics: Animals; Chromosome Aberrations; Female; Floxuridine; Insecta; Meiosis; Mitomycins; Ovum | 1973 |
Genetics of 5-fluorodeoxyuridine-resistant mutants of Neurospora crassa.
Topics: Alleles; Cell Division; Chromosome Aberrations; Crosses, Genetic; Drug Resistance, Microbial; Floxur | 1973 |
Correlated exchanges in three-marker crossing of feletion mutants of phage T4B.
Topics: Alleles; Chromosome Aberrations; Coliphages; Crosses, Genetic; DNA Viruses; DNA, Viral; Escherichia | 1974 |
Mechanism of chromosome breakage--a new theory.
Topics: Chromosome Aberrations; Chromosomes; Diphosphates; DNA; DNA Nucleotidyltransferases; Floxuridine; Pl | 1966 |