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floxacrine and Malaria

floxacrine has been researched along with Malaria in 5 studies

*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Degnan, MJ; Hung, J; Kesten, SJ; McNamara, DJ; Ortwine, DF; Uhlendorf, SE; Werbel, LM1
Fink, E; Raether, W2
Abdel-Rasoul, S; Königk, E; Mirtsch, S; Putfarken, B1
Schmidt, LH1

Other Studies

5 other study(ies) available for floxacrine and Malaria

ArticleYear
Synthesis and antimalarial properties of 1-imino derivatives of 7-chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and related structures.
    Journal of medicinal chemistry, 1992, Sep-18, Volume: 35, Issue:19

    Topics: Acridines; Animals; Antimalarials; Haplorhini; Malaria; Mice; Plasmodium berghei; Structure-Activity Relationship

1992
Antimalarial activity of floxacrine (HOE 991) II: Studies on causal prophylactic and blood schizontocidal action of floxacrine and related dihydroacridinediones against Plasmodium yoelii and P. berghei.
    Annals of tropical medicine and parasitology, 1982, Volume: 76, Issue:5

    Topics: Acridines; Animals; Antimalarials; Female; Malaria; Male; Mice; Mice, Inbred Strains; Plasmodium; Plasmodium berghei

1982
Plasmodium chabaudi-infection of mice: effects of chloroquine and mefloquine. Inhibition of ornithine decarboxylase activity.
    Tropenmedizin und Parasitologie, 1981, Volume: 32, Issue:2

    Topics: Acridines; Animals; Antimalarials; Carboxy-Lyases; Chloroquine; Enzyme Repression; Erythrocyte Membrane; Malaria; Mefloquine; Mice; Ornithine Decarboxylase Inhibitors; Piperidines; Plasmodium; Primaquine; Quinolines

1981
Antimalarial properties of floxacrine, a dihydroacridinedione derivative.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:4

    Topics: Acridines; Animals; Antimalarials; Chloroquine; Haplorhini; Macaca mulatta; Malaria; Plasmodium falciparum; Plasmodium malariae

1979
Antimalarial activity of Floxacrine (HOE 991) I. Studies on blood schizontocidal action of Floxacrine against Plasmodium berghei, P. vinckei and P. cynomolgi.
    Annals of tropical medicine and parasitology, 1979, Volume: 73, Issue:6

    Topics: 4-Aminobenzoic Acid; Acridines; Animals; Antimalarials; Blood; Cricetinae; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Microbial; Drug Tolerance; Female; Folic Acid; Haplorhini; Macaca mulatta; Malaria; Male; Mesocricetus; Mice; Plasmodium; Plasmodium berghei; Rats

1979