florbetapir-f-18 and Mononeuropathies

Multiple mononeuropathy is a rare presentation of primary (AL) amyloidosis and nerve biopsy is usually needed for diagnosis. Conventional imaging is useful to identify proximal nerve involvement but may be inadequate. We report a patient with multiple mononeuropathy whose presentation was suggestive of AL amyloid neuropathy and in whom repeated tissue biopsies were negative for amyloid (including two sensory nerves and one muscle).

Topics: Amyloid Neuropathies; Amyloidosis; Aniline Compounds; Biopsy; Ethylene Glycols; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Mononeuropathies; Neurosurgical Procedures; Positron-Emission Tomography