fleroxacin has been researched along with Skin Diseases, Bacterial in 5 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Skin Diseases, Bacterial: Skin diseases caused by bacteria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fleroxacin was given at a dosage of 400 mg once daily, and AMX/CP was given at a dosage of 500 mg/125 mg three times a day." | 2.67 | Open trial of oral fleroxacin versus amoxicillin/clavulanate in the treatment of infections of skin and soft tissue. ( Powers, RD, 1993) |
| " Clinical adverse events related to the trial medication were reported by 40 (21%) of 189 patients in the fleroxacin group and by 16 (17%) of 95 patients in the AMX/CP group." | 2.67 | Comparative efficacy and safety of oral fleroxacin and amoxicillin/clavulanate potassium in skin and soft tissue infections. ( Tassler, H, 1993) |
| "The most common diagnoses were wound infections and cellulitis, which affected 36% and 30% of the fleroxacin group, and 24% and 24% of the ceftazidime group, respectively." | 2.67 | Systemic antimicrobial therapy for skin and skin structure infections: comparison of fleroxacin and ceftazidime. ( Jungkind, DL; Parish, LC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, RN | 1 |
| Erwin, ME | 1 |
| Hager, HL | 1 |
| Hohl, PE | 1 |
| Smith, JW | 1 |
| Nichols, RL | 1 |
| Powers, RD | 1 |
| Tassler, H | 1 |
| Parish, LC | 1 |
| Jungkind, DL | 1 |
4 trials available for fleroxacin and Skin Diseases, Bacterial
| Article | Year |
|---|---|
Comparison of oral fleroxacin with oral amoxicillin/clavulanate for treatment of skin and soft tissue infections.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combin | 1993 |
Open trial of oral fleroxacin versus amoxicillin/clavulanate in the treatment of infections of skin and soft tissue.
Topics: Administration, Oral; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; | 1993 |
Comparative efficacy and safety of oral fleroxacin and amoxicillin/clavulanate potassium in skin and soft tissue infections.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Amoxicillin-Potassium | 1993 |
Systemic antimicrobial therapy for skin and skin structure infections: comparison of fleroxacin and ceftazidime.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteria; Ceftazidime; Cellulitis; Female; Fleroxacin; H | 1993 |
1 other study available for fleroxacin and Skin Diseases, Bacterial
| Article | Year |
|---|---|
Interlaboratory variations of fluoroquinolone susceptibility testing. An international study to validate the quality of microbiology results reported during the fleroxacin clinical trials.
Topics: Bacteria; Bronchitis; Clinical Trials as Topic; Europe; False Positive Reactions; Fleroxacin; Humans | 1993 |