fleroxacin has been researched along with Prostatic Hyperplasia in 2 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fleroxacin is a new fluoroquinolone with a broad antibacterial spectrum and a serum half-life of about 8-12 h." | 5.27 | In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. ( Grobecker, H; Kees, F; Metz, R; Naber, KG; Schumacher, H; Sörgel, F, 1988) |
| "Fleroxacin is a new fluoroquinolone with a broad antibacterial spectrum and a serum half-life of about 8-12 h." | 1.27 | In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue. ( Grobecker, H; Kees, F; Metz, R; Naber, KG; Schumacher, H; Sörgel, F, 1988) |
| "The drug levels in prostatic adenoma tissue were similar to the concomitantly measured plasma levels." | 1.27 | Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue. ( Grobecker, H; Kees, F; Naber, KG; Schumacher, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naber, KG | 2 |
| Sörgel, F | 1 |
| Kees, F | 2 |
| Schumacher, H | 2 |
| Metz, R | 1 |
| Grobecker, H | 2 |
2 other studies available for fleroxacin and Prostatic Hyperplasia
| Article | Year |
|---|---|
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Body Fluids; Ciprofloxacin; Fleroxacin; Gram- | 1988 |
Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue.
Topics: Administration, Oral; Aged; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxacin; Humans; | 1988 |