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fleroxacin and Pneumonia

fleroxacin has been researched along with Pneumonia in 5 studies

Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"Fleroxacin, administered intravenously at a dosage of 400 mg once a day, was compared with ceftazidime, 0."6.67Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections. ( Farkas, SA, 1993)
" Single-dose (10 mg/kg of body weight given intraperitoneally) pharmacokinetic studies performed in guinea pigs with L."5.28In vitro activities of fleroxacin against clinical isolates of Legionella spp., its pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia. ( Edelstein, MA; Edelstein, PH; Holzknecht, B, 1992)
"Fleroxacin, administered intravenously at a dosage of 400 mg once a day, was compared with ceftazidime, 0."2.67Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections. ( Farkas, SA, 1993)
" Single-dose (10 mg/kg of body weight given intraperitoneally) pharmacokinetic studies performed in guinea pigs with L."1.28In vitro activities of fleroxacin against clinical isolates of Legionella spp., its pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia. ( Edelstein, MA; Edelstein, PH; Holzknecht, B, 1992)
"Fleroxacin was inactive against S."1.28In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin. ( Beskid, G; Chan, K; Cleeland, R; Keith, DD; McGarry, CM; Siebelist, J, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, RN1
Erwin, ME1
Hager, HL1
Hohl, PE1
Farkas, SA1
Edelstein, PH1
Edelstein, MA1
Holzknecht, B1
Beskid, G1
Siebelist, J1
McGarry, CM1
Cleeland, R1
Chan, K1
Keith, DD1
Hirai, K1
Aoyama, H1
Hosaka, M1
Oomori, Y1
Niwata, Y1
Suzue, S1
Irikura, T1

Trials

1 trial available for fleroxacin and Pneumonia

ArticleYear
Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections.
    The American journal of medicine, 1993, Mar-22, Volume: 94, Issue:3A

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacteria; Bronchitis; Ceftazidime; Female; Fleroxacin

1993

Other Studies

4 other studies available for fleroxacin and Pneumonia

ArticleYear
Interlaboratory variations of fluoroquinolone susceptibility testing. An international study to validate the quality of microbiology results reported during the fleroxacin clinical trials.
    Diagnostic microbiology and infectious disease, 1993, Volume: 17, Issue:3

    Topics: Bacteria; Bronchitis; Clinical Trials as Topic; Europe; False Positive Reactions; Fleroxacin; Humans

1993
In vitro activities of fleroxacin against clinical isolates of Legionella spp., its pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Animals; Fleroxacin; Guinea Pigs; Legionella pneumophila; Legionnaires' Disease; Macrophages, Alveol

1992
In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin.
    Chemotherapy, 1990, Volume: 36, Issue:2

    Topics: Animals; Anti-Infective Agents; Bacterial Infections; Cefotaxime; Ciprofloxacin; Drug Evaluation, Pr

1990
In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative.
    Antimicrobial agents and chemotherapy, 1986, Volume: 29, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Resistance, Micr

1986