fleroxacin has been researched along with Liver Cirrhosis in 1 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this open-label study, the disposition of fleroxacin in liver disease in 12 healthy male volunteers, 6 male cirrhotics without ascites (group A), and 6 male cirrhotics with ascites (group B) was evaluated." | 7.68 | Fleroxacin pharmacokinetics in patients with liver cirrhosis. ( Blouin, RA; Foster, TS; Hamelin, BA; John, WJ; Smith, DA; Welker, HA, 1992) |
| "In this open-label study, the disposition of fleroxacin in liver disease in 12 healthy male volunteers, 6 male cirrhotics without ascites (group A), and 6 male cirrhotics with ascites (group B) was evaluated." | 3.68 | Fleroxacin pharmacokinetics in patients with liver cirrhosis. ( Blouin, RA; Foster, TS; Hamelin, BA; John, WJ; Smith, DA; Welker, HA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blouin, RA | 1 |
| Hamelin, BA | 1 |
| Smith, DA | 1 |
| Foster, TS | 1 |
| John, WJ | 1 |
| Welker, HA | 1 |
1 other study available for fleroxacin and Liver Cirrhosis
| Article | Year |
|---|---|
Fleroxacin pharmacokinetics in patients with liver cirrhosis.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Ascites; Fleroxacin; Humans; Infusions, Intravenous; | 1992 |