fleroxacin has been researched along with Leprosy in 2 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a dosage of 150 mg/kg administered daily, A-56619 is active and A-56620 is inactive against M." | 1.28 | Anti-Mycobacterium leprae activity of several quinolones studied in the mouse. ( Pattyn, SR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pattyn, SR | 1 |
| Tomioka, H | 1 |
| Sato, K | 1 |
| Saito, H | 1 |
2 other studies available for fleroxacin and Leprosy
| Article | Year |
|---|---|
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobact | 1991 |
Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria.
Topics: Animals; Disease Models, Animal; Female; Fleroxacin; Leprosy; Mice; Mice, Inbred BALB C; Microbial S | 1991 |