Page last updated: 2024-10-27

fleroxacin and Leprosy

fleroxacin has been researched along with Leprosy in 2 studies

Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
" In a dosage of 150 mg/kg administered daily, A-56619 is active and A-56620 is inactive against M."1.28Anti-Mycobacterium leprae activity of several quinolones studied in the mouse. ( Pattyn, SR, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pattyn, SR1
Tomioka, H1
Sato, K1
Saito, H1

Other Studies

2 other studies available for fleroxacin and Leprosy

ArticleYear
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1991, Volume: 59, Issue:4

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Leprosy; Mice; Mycobact

1991
Comparative in vitro and in vivo activity of fleroxacin and ofloxacin against various mycobacteria.
    Tubercle, 1991, Volume: 72, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Fleroxacin; Leprosy; Mice; Mice, Inbred BALB C; Microbial S

1991