fleroxacin has been researched along with Gonorrhea in 7 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Gonorrhea: Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a multicenter, randomized, open, comparative trial, patients with uncomplicated gonorrhea were treated with 400 mg of oral fleroxacin or 250 mg of intramuscular ceftriaxone." | 9.07 | Multicenter trial of fleroxacin versus ceftriaxone in the treatment of uncomplicated gonorrhea. ( Dalu, ZA; Douglas, JM; Handsfield, HH; Hook, EW; Jones, RB; McCormack, WM; Mogabgab, WJ; Shands, JW; Smith, BL; Viner, BL, 1993) |
| "Eighty male patients with gonococcal urethritis were randomly allocated to receive, in an open study, either a single oral 400 mg dose of fleroxacin, or, as standard therapy, a single intramuscular dose of 2." | 9.06 | Fleroxacin versus standard therapy in gonococcal urethritis. ( Ellmén, J; Lassus, A; Renkonen, OV, 1988) |
| "We performed basic and clinical studies on the effects of a new oral antimicrobial agent, fleroxacin (FLRX), a new quinolone derivative in male gonococcal urethritis." | 7.68 | [Bacteriological and clinical studies on fleroxacin in male gonococcal urethritis]. ( Hamaya, O; Miyamura, R; Ono, K; Saito, I; Suzuki, A; Yokozawa, M, 1991) |
| "In a multicenter, randomized, open, comparative trial, patients with uncomplicated gonorrhea were treated with 400 mg of oral fleroxacin or 250 mg of intramuscular ceftriaxone." | 5.07 | Multicenter trial of fleroxacin versus ceftriaxone in the treatment of uncomplicated gonorrhea. ( Dalu, ZA; Douglas, JM; Handsfield, HH; Hook, EW; Jones, RB; McCormack, WM; Mogabgab, WJ; Shands, JW; Smith, BL; Viner, BL, 1993) |
| "Eighty male patients with gonococcal urethritis were randomly allocated to receive, in an open study, either a single oral 400 mg dose of fleroxacin, or, as standard therapy, a single intramuscular dose of 2." | 5.06 | Fleroxacin versus standard therapy in gonococcal urethritis. ( Ellmén, J; Lassus, A; Renkonen, OV, 1988) |
| "We performed basic and clinical studies on the effects of a new oral antimicrobial agent, fleroxacin (FLRX), a new quinolone derivative in male gonococcal urethritis." | 3.68 | [Bacteriological and clinical studies on fleroxacin in male gonococcal urethritis]. ( Hamaya, O; Miyamura, R; Ono, K; Saito, I; Suzuki, A; Yokozawa, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, BL | 1 |
| Mogabgab, WJ | 1 |
| Dalu, ZA | 1 |
| Jones, RB | 1 |
| Douglas, JM | 1 |
| Handsfield, HH | 1 |
| Hook, EW | 1 |
| Viner, BL | 1 |
| Shands, JW | 1 |
| McCormack, WM | 1 |
| Kam, KM | 1 |
| Wong, PW | 1 |
| Cheung, MM | 1 |
| Ho, NK | 1 |
| Lassus, A | 2 |
| Abath Filho, L | 1 |
| Santos Júnior, MF | 1 |
| Belli, L | 1 |
| Saito, I | 1 |
| Suzuki, A | 1 |
| Yokozawa, M | 1 |
| Ono, K | 1 |
| Miyamura, R | 1 |
| Hamaya, O | 1 |
| Boerema, JB | 1 |
| Moesker, HL | 1 |
| Van de Rhee, HJ | 1 |
| Renkonen, OV | 1 |
| Ellmén, J | 1 |
| Eugster, H | 1 |
| Eichmann, A | 1 |
3 trials available for fleroxacin and Gonorrhea
| Article | Year |
|---|---|
Multicenter trial of fleroxacin versus ceftriaxone in the treatment of uncomplicated gonorrhea.
Topics: Administration, Oral; Adolescent; Adult; Ceftriaxone; Chlamydia Infections; Chlamydia trachomatis; F | 1993 |
Comparison of fleroxacin and penicillin G plus probenecid in the treatment of acute uncomplicated gonococcal infections.
Topics: Acute Disease; Adolescent; Adult; Drug Therapy, Combination; Fleroxacin; Gonorrhea; Humans; Male; Mi | 1992 |
Fleroxacin versus standard therapy in gonococcal urethritis.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Follow-Up Studies; Gonorrhea; Humans; Male; | 1988 |
4 other studies available for fleroxacin and Gonorrhea
| Article | Year |
|---|---|
Detection of quinolone-resistant Neisseria gonorrhoeae.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Enoxacin; Female; Fleroxacin; Fluo | 1996 |
[Bacteriological and clinical studies on fleroxacin in male gonococcal urethritis].
Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Drug Evaluation; Drug Resistance, Micr | 1991 |
Fleroxacin (Ro 23-6240) in the treatment of gonorrhoea.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Gonorrhea; Humans; Male | 1988 |
Single dose therapy with Ro 23-6240 in patients suffering from acute, non-complicated gonococcal infection.
Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Gonorrhea; Humans; Male | 1987 |