Page last updated: 2024-10-27

fleroxacin and Bleb

fleroxacin has been researched along with Bleb in 3 studies

Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.

Research Excerpts

ExcerptRelevanceReference
"Serum, blister fluid, and paper disk samples were analyzed by large-plate microbiologic assay."2.67Penetration of fleroxacin and ciprofloxacin into skin blister fluid: a comparative study. ( Lubowski, TJ; Nightingale, C; Quintiliani, R; Sweeney, K; Zhi, J, 1992)
" The elimination half-life in serum was 11."1.27Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone. ( Ashby, J; Griggs, DJ; Kirkpatrick, B; Wise, R, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lubowski, TJ1
Nightingale, C1
Sweeney, K1
Quintiliani, R1
Zhi, J1
Limberg, J1
LeBel, M1
Derendorf, H1
Wise, R1
Kirkpatrick, B1
Ashby, J1
Griggs, DJ1

Trials

1 trial available for fleroxacin and Bleb

ArticleYear
Penetration of fleroxacin and ciprofloxacin into skin blister fluid: a comparative study.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:3

    Topics: Administration, Oral; Adult; Blister; Body Fluids; Ciprofloxacin; Female; Fleroxacin; Humans; Male;

1992

Other Studies

2 other studies available for fleroxacin and Bleb

ArticleYear
Evaluation of free tissue concentrations of fleroxacin after oral administration.
    Pharmaceutical research, 1990, Volume: 7, Issue:4

    Topics: Administration, Oral; Adult; Blister; Chromatography, High Pressure Liquid; Ciprofloxacin; Fleroxaci

1990
Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Blister; Ciprofloxacin; Exudates and Transudates

1987