fleroxacin has been researched along with Bacteremia in 5 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a multicenter, randomized trial, we compared the efficacy, safety, and length of hospital stay for patients with staphylococcal infections treated either with an oral combination of a fluoroquinolone (fleroxacin) plus rifampicin or with standard parenteral treatment (flucloxacillin or vancomycin)." | 5.11 | A randomized clinical trial to compare fleroxacin-rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection. ( Bregenzer, T; Flueckiger, U; Francioli, P; Genné, D; Harbarth, S; Jacobs, F; Lew, DP; Petignat, C; Schockmel, G; Schrenzel, J; Zimmerli, W, 2004) |
| "The objective of this open label, non-comparative study was to evaluate the efficacy and safety of fleroxacin 400mg administered orally once daily to patients with acute osteomyelitis and/or acute septic arthritis." | 5.07 | Clinical evaluation of fleroxacin in the treatment of bone and joint infections. ( Chen, YS; Cheng, DL; de Garis, ST; Hsieh, TL; Lin, HH; Liu, CY; Liu, YC; Wang, RS; Yen, MY, 1992) |
| "Fleroxacin is a new broad-spectrum quinolone which can be given by the oral route." | 1.29 | Single-dose pharmacokinetics of oral fleroxacin in bacteremic patients. ( Cerruti, F; Herrmann, M; Hirschel, B; Leemann, T; Lew, DP; Portmann, R; Schrenzel, J; Weidekamm, E, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schrenzel, J | 2 |
| Harbarth, S | 1 |
| Schockmel, G | 1 |
| Genné, D | 1 |
| Bregenzer, T | 1 |
| Flueckiger, U | 1 |
| Petignat, C | 1 |
| Jacobs, F | 1 |
| Francioli, P | 1 |
| Zimmerli, W | 1 |
| Lew, DP | 2 |
| Cerruti, F | 1 |
| Herrmann, M | 1 |
| Leemann, T | 1 |
| Weidekamm, E | 1 |
| Portmann, R | 1 |
| Hirschel, B | 1 |
| Siristonpun, Y | 1 |
| Rojnpisarnvong, V | 1 |
| Chongchitmate, A | 1 |
| Srimuang, S | 1 |
| Tanphaichitra, D | 1 |
| Kerr, KG | 1 |
| Armitage, HT | 1 |
| McWhinney, PH | 1 |
| Liu, YC | 1 |
| Cheng, DL | 1 |
| Liu, CY | 1 |
| de Garis, ST | 1 |
| Lin, HH | 1 |
| Hsieh, TL | 1 |
| Yen, MY | 1 |
| Wang, RS | 1 |
| Chen, YS | 1 |
2 trials available for fleroxacin and Bacteremia
| Article | Year |
|---|---|
A randomized clinical trial to compare fleroxacin-rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection.
Topics: Administration, Oral; Adult; Aged; Bacteremia; Catheters, Indwelling; Drug Therapy, Combination; Fem | 2004 |
Clinical evaluation of fleroxacin in the treatment of bone and joint infections.
Topics: Acute Disease; Adult; Aged; Arthritis, Infectious; Bacteremia; Female; Fleroxacin; Humans; Male; Mid | 1992 |
3 other studies available for fleroxacin and Bacteremia
| Article | Year |
|---|---|
Single-dose pharmacokinetics of oral fleroxacin in bacteremic patients.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Bacteremia; Female; Fleroxacin; H | 1994 |
In vitro activity of sparfloxacin against selected gram-negative blood culture isolates.
Topics: Anti-Infective Agents; Bacteremia; Culture Media; Fleroxacin; Fluoroquinolones; Gram-Negative Bacter | 1995 |
Activity of quinolones against viridans group streptococci isolated from blood cultures of patients with haematological malignancy.
Topics: Adult; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Fleroxacin; Fluoroquinolones; Hematologic N | 1999 |