fleroxacin has been researched along with Acute Disease in 10 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetics of fleroxacin, a new broad-spectrum fluoroquinolone, were measured by positron emission tomography (PET) with [18F]fleroxacin in five patients with acute bacterial exacerbations of chronic bronchitis and in five patients with symptomatic, complicated urinary tract infection." | 9.08 | Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography. ( Alpert, NM; Babich, JW; Bonab, A; Chodosh, S; Cleeland, R; Correia, JA; Fischman, AJ; Kamitsuka, P; Liu, YY; Livni, E; McGovern, F; Prosser, BL; Rubin, RH, 1996) |
| "The purpose of this work was to evaluate the efficacy and safety of a single dose of 400 mg of fleroxacin for the empiric antibiotic treatment of acute diarrhea in adult patients." | 9.08 | [Single dose of fleroxacin for the treatment of adult acute diarrhea]. ( Casero, R; Colazo, A; Gandini, B; Kitzmann, P; Lalik, S; Monterisi, A; Patrito, V; Pereyra de Santiago, O; Polo Friz, H; Rocchi, M; Rojo, S; Serra, J, 1997) |
| "The objective of this double-blind, multicenter study was to compare the efficacy and safety of oral fleroxacin, 400 mg once daily for 7 days, with amoxicillin, 500 mg administered every 8 hours for 7 days, in the treatment of acute exacerbation of chronic bronchitis." | 9.07 | Fleroxacin versus amoxicillin in the treatment of acute exacerbation of chronic bronchitis. ( Ulmer, W, 1993) |
| "In a multicenter study the efficacy and safety of oral fleroxacin at 400 mg once a day and amoxicillin at 500 mg three times daily for 7 days were compared for the treatment of patients with acute bacterial exacerbations of chronic bronchitis due to drug-susceptible bacteria." | 9.07 | Efficacy of fleroxacin versus amoxicillin in acute exacerbations of chronic bronchitis. ( Chodosh, S, 1993) |
| "Fleroxacin, administered intravenously at a dosage of 400 mg once a day, was compared with ceftazidime, 0." | 6.67 | Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections. ( Farkas, SA, 1993) |
| "The pharmacokinetics of fleroxacin, a new broad-spectrum fluoroquinolone, were measured by positron emission tomography (PET) with [18F]fleroxacin in five patients with acute bacterial exacerbations of chronic bronchitis and in five patients with symptomatic, complicated urinary tract infection." | 5.08 | Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography. ( Alpert, NM; Babich, JW; Bonab, A; Chodosh, S; Cleeland, R; Correia, JA; Fischman, AJ; Kamitsuka, P; Liu, YY; Livni, E; McGovern, F; Prosser, BL; Rubin, RH, 1996) |
| "The purpose of this work was to evaluate the efficacy and safety of a single dose of 400 mg of fleroxacin for the empiric antibiotic treatment of acute diarrhea in adult patients." | 5.08 | [Single dose of fleroxacin for the treatment of adult acute diarrhea]. ( Casero, R; Colazo, A; Gandini, B; Kitzmann, P; Lalik, S; Monterisi, A; Patrito, V; Pereyra de Santiago, O; Polo Friz, H; Rocchi, M; Rojo, S; Serra, J, 1997) |
| "The objective of this double-blind, multicenter study was to compare the efficacy and safety of oral fleroxacin, 400 mg once daily for 7 days, with amoxicillin, 500 mg administered every 8 hours for 7 days, in the treatment of acute exacerbation of chronic bronchitis." | 5.07 | Fleroxacin versus amoxicillin in the treatment of acute exacerbation of chronic bronchitis. ( Ulmer, W, 1993) |
| "In a multicenter study the efficacy and safety of oral fleroxacin at 400 mg once a day and amoxicillin at 500 mg three times daily for 7 days were compared for the treatment of patients with acute bacterial exacerbations of chronic bronchitis due to drug-susceptible bacteria." | 5.07 | Efficacy of fleroxacin versus amoxicillin in acute exacerbations of chronic bronchitis. ( Chodosh, S, 1993) |
| "The objective of this open label, non-comparative study was to evaluate the efficacy and safety of fleroxacin 400mg administered orally once daily to patients with acute osteomyelitis and/or acute septic arthritis." | 5.07 | Clinical evaluation of fleroxacin in the treatment of bone and joint infections. ( Chen, YS; Cheng, DL; de Garis, ST; Hsieh, TL; Lin, HH; Liu, CY; Liu, YC; Wang, RS; Yen, MY, 1992) |
| "Fleroxacin, administered intravenously at a dosage of 400 mg once a day, was compared with ceftazidime, 0." | 2.67 | Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections. ( Farkas, SA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ulmer, W | 1 |
| Chodosh, S | 2 |
| Farkas, SA | 1 |
| Fischman, AJ | 1 |
| Livni, E | 1 |
| Babich, JW | 1 |
| Alpert, NM | 1 |
| Bonab, A | 1 |
| McGovern, F | 1 |
| Kamitsuka, P | 1 |
| Liu, YY | 1 |
| Cleeland, R | 1 |
| Prosser, BL | 1 |
| Correia, JA | 1 |
| Rubin, RH | 1 |
| Polo Friz, H | 1 |
| Kitzmann, P | 1 |
| Lalik, S | 1 |
| Serra, J | 1 |
| Rojo, S | 1 |
| Rocchi, M | 1 |
| Monterisi, A | 1 |
| Colazo, A | 1 |
| Casero, R | 1 |
| Patrito, V | 1 |
| Pereyra de Santiago, O | 1 |
| Gandini, B | 1 |
| Lassus, A | 1 |
| Abath Filho, L | 1 |
| Santos Júnior, MF | 1 |
| Belli, L | 1 |
| Liu, YC | 1 |
| Cheng, DL | 1 |
| Liu, CY | 1 |
| de Garis, ST | 1 |
| Lin, HH | 1 |
| Hsieh, TL | 1 |
| Yen, MY | 1 |
| Wang, RS | 1 |
| Chen, YS | 1 |
| Møller, BR | 1 |
| Kaspersen, P | 1 |
| Mamsen, A | 1 |
| Korsager, B | 1 |
| Quitzau, K | 1 |
| Kosmidis, J | 1 |
| Gargalianos, P | 1 |
| Adamis, G | 1 |
| Petropoulou, D | 1 |
| Makris, D | 1 |
| Eugster, H | 1 |
| Eichmann, A | 1 |
8 trials available for fleroxacin and Acute Disease
| Article | Year |
|---|---|
Fleroxacin versus amoxicillin in the treatment of acute exacerbation of chronic bronchitis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amoxicillin; Bacteria; Bronchitis; Chronic Disease; D | 1993 |
Efficacy of fleroxacin versus amoxicillin in acute exacerbations of chronic bronchitis.
Topics: Acute Disease; Aged; Amoxicillin; Bacteria; Bacterial Infections; Bronchitis; Chronic Disease; Confi | 1993 |
Intravenous fleroxacin versus ceftazidime in the treatment of acute nonpneumococcal lower respiratory tract infections.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacteria; Bronchitis; Ceftazidime; Female; Fleroxacin | 1993 |
Pharmacokinetics of [18F]fleroxacin in patients with acute exacerbations of chronic bronchitis and complicated urinary tract infection studied by positron emission tomography.
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Bronchitis; Chronic Disease; Fleroxacin; Fluorine | 1996 |
[Single dose of fleroxacin for the treatment of adult acute diarrhea].
Topics: Acute Disease; Adult; Aged; Anti-Infective Agents; Diarrhea; Double-Blind Method; Female; Fleroxacin | 1997 |
Comparison of fleroxacin and penicillin G plus probenecid in the treatment of acute uncomplicated gonococcal infections.
Topics: Acute Disease; Adolescent; Adult; Drug Therapy, Combination; Fleroxacin; Gonorrhea; Humans; Male; Mi | 1992 |
Clinical evaluation of fleroxacin in the treatment of bone and joint infections.
Topics: Acute Disease; Adult; Aged; Arthritis, Infectious; Bacteremia; Female; Fleroxacin; Humans; Male; Mid | 1992 |
Fleroxacin in single dose oral therapy of uncomplicated lower urinary tract infection.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Amoxicillin; Anti-Infective Agents; Ciproflo | 1988 |
2 other studies available for fleroxacin and Acute Disease
| Article | Year |
|---|---|
Fleroxacin in the treatment of uncomplicated acute cystitis in women.
Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Cystitis; Female; Fleroxacin; Follow-Up | 1988 |
Single dose therapy with Ro 23-6240 in patients suffering from acute, non-complicated gonococcal infection.
Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Fleroxacin; Gonorrhea; Humans; Male | 1987 |