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fleroxacin and Acquired Immunodeficiency Syndrome

fleroxacin has been researched along with Acquired Immunodeficiency Syndrome in 1 studies

Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections."9.06Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989)
"In Kenya, researchers enrolled 53, men aged 18-60 years with chancroid who enrolled at the Nairobi City Council Special Treatment Clinic in a clinical trial to test the efficacy of fleroxacin in clinical Haemophilus ducreyi infections."5.06Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya. ( Cameron, DW; D'Costa, L; MacDonald, KS; Ndinya-Achola, JO; Plummer, FA; Ronald, AR, 1989)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MacDonald, KS1
Cameron, DW1
D'Costa, L1
Ndinya-Achola, JO1
Plummer, FA1
Ronald, AR1

Trials

1 trial available for fleroxacin and Acquired Immunodeficiency Syndrome

ArticleYear
Evaluation of fleroxacin (RO 23-6240) as single-oral-dose therapy of culture-proven chancroid in Nairobi, Kenya.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents;

1989