Page last updated: 2024-10-27

flecainide and Wolff-Parkinson-White Syndrome

flecainide has been researched along with Wolff-Parkinson-White Syndrome in 50 studies

Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).

Wolff-Parkinson-White Syndrome: A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulses are abnormally conducted to the HEART VENTRICLES via an ACCESSORY CONDUCTING PATHWAY that is located between the wall of the right or left atria and the ventricles, also known as a BUNDLE OF KENT. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Research Excerpts

ExcerptRelevanceReference
"The effects of intravenous flecainide and propafenone (2 mg/kg) administered in random order were compared in 16 patients with Wolff-Parkinson-White syndrome."9.07Effects of flecainide on atrial electrophysiology in the Wolff-Parkinson-White syndrome. ( Camm, AJ; Katritsis, D; Nunain, SO, 1992)
"In 34 patients with a symptomatic accessory atrioventricular connection the reversible protective effect of orally administered flecainide (300 mg/day) and of propafenone (900 mg/day) in control of ventricular response during atrial fibrillation by exercise was assessed."9.07Reversible protective effect of propafenone or flecainide during atrial fibrillation in patients with an accessory atrioventricular connection. ( Auricchio, A, 1992)
"We compared the electrophysiological effects of intravenous propafenone and flecainide on accessory pathway conduction by a randomized crossover study in 16 patients with Wolff-Parkinson-White syndrome."9.07A comparison of intravenous propafenone and flecainide in the treatment of tachycardias associated with the Wolff-Parkinson-White syndrome. ( Camm, AJ; Garratt, CJ; Gill, J; Linker, NJ; O'Nunain, S; Ward, DE, 1991)
"This report summarizes efficacy and safety data on the use of flecainide acetate for supraventricular arrhythmias."8.78Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias. ( Hohnloser, SH; Zabel, M, 1992)
"The effects of flecainide on electrophysiologic parameters and arrhythmias in the Wolff-Parkinson-White syndrome were reviewed."8.78Flecainide in the Wolff-Parkinson-White syndrome. ( Crozier, I, 1992)
"We determined the effects of combined sotalol (160 mg/day) and flecainide (200 mg/day) in 15 patients with the Wolff-Parkinson-White syndrome."7.68Combined sotalol and flecainide given at low dosage in patients with the Wolff-Parkinson-White syndrome. ( Gössinger, HD; Mösslacher, H; Siostrzonek, P, 1990)
"Four neonates with Wolff-Parkinson-White syndrome developed supraventricular tachycardia and received flecainide orally after reduction of the arrhythmia."7.68[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants]. ( Casasoprana, A; Denjoy, I; Jacqz-Aigrain, E; Lupoglazoff, JM, 1991)
"Drug efficacy and pharmacokinetics were assessed in 63 patients, aged 5 days to 30 years (mean 8 years), who received flecainide acetate for control of resistant arrhythmias."7.67Flecainide acetate for resistant arrhythmias in the young: efficacy and pharmacokinetics. ( Fredell, P; Garson, A; Gothing, C; McQuinn, RL; Perry, JC; Smith, RT, 1989)
"The response of sustained supraventricular tachycardia to intravenous and oral flecainide acetate was investigated in 5 children, aged 5."7.67Use of flecainide acetate for refractory junctional tachycardias in children with the Wolff-Parkinson-White syndrome. ( Jones, S; Shinebourne, EA; Ward, DE, 1986)
"Flecainide is reported to be effective in patients with paroxysmal tachycardias, but its effect on rapid ventricular response over accessory atrioventricular pathway during atrial fibrillation is not known."7.67Evaluation of flecainide acetate in rapid atrial fibrillation complicating Wolff-Parkinson-White syndrome. ( Fromer, MA; Gloor, HO; Kappenberger, LJ; Shenasa, M, 1985)
"The effect of flecainide in 12 patients with the Wolff-Parkinson-White syndrome was analyzed with respect to the anterograde and retrograde conduction properties of the accessory pathway, the modes of initiation and termination of circus movement tachycardias, and the ventricular response during induced atrial fibrillation."7.66Effects of flecainide on electrophysiological properties of accessory pathways in the Wolff-Parkinson-White syndrome. ( Berthold, R; Buss, J; Krämer, A; Mitrović, V; Musial, WJ; Neuss, H; Schlepper, M, 1983)
"Flecainide was effective in all patients: Seven became asymptomatic, and six experimented isolated episodes of palpitations."5.36Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome. ( Brines, J; Martínez-Costa, C; Morell, S; Núñez, F; Ruiz-Granell, R, 2010)
"Isoproterenol infusion was given in dosages of 1 to 4 micrograms/min to increase the heart rate at rest by 50%."5.28Reversal of electrophysiologic effects of flecainide on the accessory pathway by isoproterenol in the Wolff-Parkinson-White syndrome. ( Estes, NA; Manolis, AS, 1989)
"The effects of intravenous flecainide and propafenone (2 mg/kg) administered in random order were compared in 16 patients with Wolff-Parkinson-White syndrome."5.07Effects of flecainide on atrial electrophysiology in the Wolff-Parkinson-White syndrome. ( Camm, AJ; Katritsis, D; Nunain, SO, 1992)
"In 34 patients with a symptomatic accessory atrioventricular connection the reversible protective effect of orally administered flecainide (300 mg/day) and of propafenone (900 mg/day) in control of ventricular response during atrial fibrillation by exercise was assessed."5.07Reversible protective effect of propafenone or flecainide during atrial fibrillation in patients with an accessory atrioventricular connection. ( Auricchio, A, 1992)
"We compared the electrophysiological effects of intravenous propafenone and flecainide on accessory pathway conduction by a randomized crossover study in 16 patients with Wolff-Parkinson-White syndrome."5.07A comparison of intravenous propafenone and flecainide in the treatment of tachycardias associated with the Wolff-Parkinson-White syndrome. ( Camm, AJ; Garratt, CJ; Gill, J; Linker, NJ; O'Nunain, S; Ward, DE, 1991)
"Eighty-three patients with paroxysmal supraventricular tachycardia (Wolff-Parkinson-White syndrome in 47 patients and atrioventricular nodal reentry in 36 patients) underwent electrophysiologic study before and after intravenous administration of flecainide."5.06Long-term efficacy and safety of flecainide for supraventricular tachycardia. ( Neuss, H; Schlepper, M, 1988)
"This report summarizes efficacy and safety data on the use of flecainide acetate for supraventricular arrhythmias."4.78Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias. ( Hohnloser, SH; Zabel, M, 1992)
"The effects of flecainide on electrophysiologic parameters and arrhythmias in the Wolff-Parkinson-White syndrome were reviewed."4.78Flecainide in the Wolff-Parkinson-White syndrome. ( Crozier, I, 1992)
"Flecainide is a class Ic antidysrhythmic agent used to prevent and treat both ventricular and supraventricular tachycardias, including atrial fibrillation, atrioventricular nodal re-entrant tachycardia, and Wolff-Parkinson-White syndrome."3.96The Case of Flecainide Toxicity: What to Look for and How to Treat. ( Newson, JM; Santos, CD; Todd, BR; Walters, BL, 2020)
"A 73 year-old patient with Wolff-Parkinson-White syndrome and paroxysmic supraventricular tachycardia developed an acute reversible encephalopathy within 15 days of initiation of flecainide."3.69Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy. ( Ghika, J; Goy, JJ; Naegeli, C; Regli, F, 1994)
"Four neonates with Wolff-Parkinson-White syndrome developed supraventricular tachycardia and received flecainide orally after reduction of the arrhythmia."3.68[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants]. ( Casasoprana, A; Denjoy, I; Jacqz-Aigrain, E; Lupoglazoff, JM, 1991)
"We determined the effects of combined sotalol (160 mg/day) and flecainide (200 mg/day) in 15 patients with the Wolff-Parkinson-White syndrome."3.68Combined sotalol and flecainide given at low dosage in patients with the Wolff-Parkinson-White syndrome. ( Gössinger, HD; Mösslacher, H; Siostrzonek, P, 1990)
"A 46 year-old woman with Wolff-Parkinson-White syndrome (postero-septal accessory pathway), symptomatic for recurrent episodes of nonsustained paroxismal supraventricular tachycardia (PSVT), was empirically treated with propafenone (600 mg/day)."3.68Opposite effects of propafenone and flecainide in a patient with reciprocating supraventricular tachycardia. ( Calvi, V; di Bona, G; Manzoli, U; Montenero, AS; Natale, A; Santarelli, P, 1990)
"In order to identify the flecainide plasma concentrations capable to inhibit the abnormal Kent's pathways, 9 patients affected by a Wolff-Parkinson-White syndrome were studied."3.67[Pharmacodynamics and pharmacokinetics of flecainide in cardiac pre-excitation of the bundle of Kent]. ( Casiglia, E; Marchese, D; Martines, C; Padrini, R; Pessina, AC; Piovan, D; Sforza, G, 1989)
"In order to assess the value of the various atrial pacing techniques employed to evaluate the anterograde conduction of the accessory pathway and the effect of antiarrhythmic agents in Wolff-Parkinson-White syndrome, transesophageal atrial pacing was performed in 12 patients before and during treatment with oral flecainide acetate in doses of 200 mg per day."3.67[Value of transesophageal auricular stimulation for evaluating the accessory pathway and effect of treatment in Wolf-Parkinson-White syndrome]. ( Bareiss, P; Facello, A; Kieny, JR; Kraenner, C; Mossard, JM; Roul, G; Sacrez, A, 1989)
"The response of sustained supraventricular tachycardia to intravenous and oral flecainide acetate was investigated in 5 children, aged 5."3.67Use of flecainide acetate for refractory junctional tachycardias in children with the Wolff-Parkinson-White syndrome. ( Jones, S; Shinebourne, EA; Ward, DE, 1986)
"Flecainide is reported to be effective in patients with paroxysmal tachycardias, but its effect on rapid ventricular response over accessory atrioventricular pathway during atrial fibrillation is not known."3.67Evaluation of flecainide acetate in rapid atrial fibrillation complicating Wolff-Parkinson-White syndrome. ( Fromer, MA; Gloor, HO; Kappenberger, LJ; Shenasa, M, 1985)
"Drug efficacy and pharmacokinetics were assessed in 63 patients, aged 5 days to 30 years (mean 8 years), who received flecainide acetate for control of resistant arrhythmias."3.67Flecainide acetate for resistant arrhythmias in the young: efficacy and pharmacokinetics. ( Fredell, P; Garson, A; Gothing, C; McQuinn, RL; Perry, JC; Smith, RT, 1989)
"The effect of flecainide in 12 patients with the Wolff-Parkinson-White syndrome was analyzed with respect to the anterograde and retrograde conduction properties of the accessory pathway, the modes of initiation and termination of circus movement tachycardias, and the ventricular response during induced atrial fibrillation."3.66Effects of flecainide on electrophysiological properties of accessory pathways in the Wolff-Parkinson-White syndrome. ( Berthold, R; Buss, J; Krämer, A; Mitrović, V; Musial, WJ; Neuss, H; Schlepper, M, 1983)
" Little justification for the use of agents or dosing in children is available."2.40Pharmacologic management of supraventricular tachycardias in children. Part 1: Wolff-Parkinson-White and atrioventricular nodal reentry. ( Kuhn, RJ; Luedtke, SA; McCaffrey, FM, 1997)
"Flecainide was effective in all patients: Seven became asymptomatic, and six experimented isolated episodes of palpitations."1.36Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome. ( Brines, J; Martínez-Costa, C; Morell, S; Núñez, F; Ruiz-Granell, R, 2010)
"Patient 1 had frequent episodes of paroxysmal atrial fibrillation resistant to Class IA drugs."1.30ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome. ( Fujiki, A; Hayashi, H; Inoue, H; Mizumaki, K; Nagasawa, H; Usui, M, 1999)
"Isoproterenol infusion was given in dosages of 1 to 4 micrograms/min to increase the heart rate at rest by 50%."1.28Reversal of electrophysiologic effects of flecainide on the accessory pathway by isoproterenol in the Wolff-Parkinson-White syndrome. ( Estes, NA; Manolis, AS, 1989)
"Flecainide acetate was administered intravenously and orally to 12 consecutive children, aged 1-15 years, presenting with arrhythmias that were life threatening or resistant to conventional medical treatment."1.27The response of paediatric arrhythmias to intravenous and oral flecainide. ( Campbell, RW; Wren, C, 1987)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199022 (44.00)18.7374
1990's19 (38.00)18.2507
2000's4 (8.00)29.6817
2010's4 (8.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Sekine, M1
Masutani, S1
Imamura, T1
Iwamoto, Y1
Muraji, S1
Yoshiba, S1
Ishido, H1
Sumitomo, N1
Newson, JM1
Santos, CD1
Walters, BL1
Todd, BR1
Suzuki, S1
Hokosaki, T1
Iwamoto, M1
Tanel, RE1
Núñez, F1
Ruiz-Granell, R1
Martínez-Costa, C1
Morell, S1
Brines, J1
Brace, S1
Kanemoto, M1
Shimizu, A1
Yamagata, T1
Esato, M1
Ueyama, T1
Yoshiga, Y1
Kakugawa, H1
Kametani, R1
Inoue, N1
Sawa, A1
Matsuzaki, M1
Orning, OM1
Neuss, H3
Buss, J1
Schlepper, M2
Berthold, R1
Mitrović, V1
Krämer, A1
Musial, WJ1
Ghika, J1
Goy, JJ1
Naegeli, C1
Regli, F1
Lee, CY1
Teo, WS1
Blanch, G1
Walkinshaw, SA1
Walsh, K1
Auricchio, A2
Auricchio, U1
Chiariello, L1
Mannino, MM1
Mehta, D1
Gomes, JA1
Luedtke, SA1
Kuhn, RJ1
McCaffrey, FM1
Fujiki, A1
Usui, M1
Nagasawa, H1
Mizumaki, K1
Hayashi, H1
Inoue, H1
Kähler, C1
Schleussner, E1
Schneider, U1
Seewald, HJ1
Price, JF1
Kertesz, NJ1
Snyder, CS1
Friedman, RA1
Fenrich, AL1
Hohnloser, SH1
Zabel, M1
Crozier, I1
Camm, AJ3
Katritsis, D1
Nunain, SO1
Wiseman, MN1
Elstob, JE1
Nathan, AW1
O'Nunain, S1
Garratt, CJ1
Linker, NJ1
Gill, J1
Ward, DE2
Lupoglazoff, JM1
Jacqz-Aigrain, E1
Denjoy, I2
Casasoprana, A2
Song, Y1
Lucet, V1
Do Ngoc, D1
Magnier, S1
Coumel, P2
Gössinger, HD1
Siostrzonek, P1
Mösslacher, H1
Talard, P1
Cointe, R1
Bru, P1
Moyal, C1
Lacombe, P1
Bremondy, M1
Levy, S1
Gerard, R1
Montenero, AS1
Natale, A1
di Bona, G1
Calvi, V1
Santarelli, P1
Manzoli, U1
Stuart, AG1
Wren, C2
Bain, HH1
Manolis, AS2
Salem, DN1
Estes, NA2
Perry, JC1
McQuinn, RL1
Smith, RT1
Gothing, C1
Fredell, P1
Garson, A1
Casiglia, E2
Padrini, R1
Piovan, D2
Marchese, D1
Sforza, G1
Martines, C2
Pessina, AC1
Kieny, JR1
Kraenner, C1
Facello, A1
Roul, G1
Mossard, JM1
Bareiss, P1
Sacrez, A1
Borgeat, A1
Grbic, M1
Campbell, RW1
Moretto, R1
Crijns, HJ1
den Heijer, P1
van Wijk, LM1
Lie, KI1
Klersy, C1
Marangoni, E1
Salerno, JA1
Guasti, L1
Chimienti, M1
Morellini, MC1
li Bergolis, M1
Moizi, M1
Tronconi, L1
Bobba, P1
Casciani, M1
Podestà, M1
Carolis, S1
Bargellini, F1
Anticoli Borza, S1
Chouty, F1
Leclercq, JF2
Brembilla-Perrot, B1
Admant, P1
Le Helloco, A1
Pernot, C1
Fauchier, JP1
Cosnay, P1
Rouesnel, P1
Moquet, B1
Bonnet, P1
Scala, PJ1
Demeyer, JF1
Jones, S1
Shinebourne, EA1
Kappenberger, LJ1
Fromer, MA1
Shenasa, M1
Gloor, HO1
Slama, R1

Reviews

3 reviews available for flecainide and Wolff-Parkinson-White Syndrome

ArticleYear
Pharmacologic management of supraventricular tachycardias in children. Part 1: Wolff-Parkinson-White and atrioventricular nodal reentry.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:10

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Calcium Channel Blockers; Child; Ch

1997
Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias.
    The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Flecainide; Humans; Meta-Analysis as Topi

1992
Flecainide in the Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Flecainide; Heart Conduction Syst

1992

Trials

6 trials available for flecainide and Wolff-Parkinson-White Syndrome

ArticleYear
Partial reversal by exercise of protective effect in atrial fibrillation inducibility in patients with an accessory atrioventricular connection: comparison between flecainide and propafenone.
    Giornale italiano di cardiologia, 1994, Volume: 24, Issue:2

    Topics: Adult; Arrhythmias, Cardiac; Electric Stimulation; Exercise Test; Female; Flecainide; Humans; Male;

1994
Effects of flecainide on atrial electrophysiology in the Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5

    Topics: Atrial Fibrillation; Atrial Function; Cardiac Catheterization; Cardiac Pacing, Artificial; Flecainid

1992
Reversible protective effect of propafenone or flecainide during atrial fibrillation in patients with an accessory atrioventricular connection.
    American heart journal, 1992, Volume: 124, Issue:4

    Topics: Adult; Atrial Fibrillation; Atrioventricular Node; Cardiac Pacing, Artificial; Exercise; Exercise Te

1992
A comparison of intravenous propafenone and flecainide in the treatment of tachycardias associated with the Wolff-Parkinson-White syndrome.
    Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:11 Pt 2

    Topics: Adult; Atrial Fibrillation; Cardiac Pacing, Artificial; Female; Flecainide; Humans; Male; Propafenon

1991
[Wolff-Parkinson-White syndrome. Value of intravenous flecainide for detecting Kent's pathways with short refractory period].
    Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Child; Electrocardiography; Electrophysiology; Female; Flecainide; Heart Conducti

1990
Long-term efficacy and safety of flecainide for supraventricular tachycardia.
    The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6

    Topics: Cardiac Pacing, Artificial; Clinical Trials as Topic; Electrocardiography; Electrophysiology; Flecai

1988

Other Studies

41 other studies available for flecainide and Wolff-Parkinson-White Syndrome

ArticleYear
Improvement in Dyssynchrony with Pharmacological Ablation of Right-Sided Accessory Pathway-Induced Cardiomyopathy in Infants.
    International heart journal, 2019, Sep-27, Volume: 60, Issue:5

    Topics: Accessory Atrioventricular Bundle; Cardiomyopathy, Dilated; Echocardiography, Doppler; Electrocardio

2019
The Case of Flecainide Toxicity: What to Look for and How to Treat.
    The Journal of emergency medicine, 2020, Volume: 59, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Humans; Middle

2020
Pharmacologic therapy with flecainide for asymptomatic Wolff-Parkinson-White syndrome in an infant with severe left ventricular dyssynchrony.
    Cardiology in the young, 2018, Volume: 28, Issue:7

    Topics: Anti-Arrhythmia Agents; Echocardiography; Electrocardiography, Ambulatory; Flecainide; Heart Ventric

2018
ECGs in the ED.
    Pediatric emergency care, 2008, Volume: 24, Issue:11

    Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Emergency Service, Hospital; Fleca

2008
Safety and efficacy of flecainide in the treatment of symptomatic children with Wolff-Parkinson-White syndrome.
    Pediatric cardiology, 2010, Volume: 31, Issue:8

    Topics: Adolescent; Anti-Arrhythmia Agents; Catheter Ablation; Child; Child, Preschool; Electrocardiography;

2010
Emergency treatment of Wolff-Parkinson-White syndrome.
    Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association, 2011, Volume: 18, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Causality; Electric Countershock; Electrocardiography; Emergency

2011
Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:4

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Electrophysiologic Techniques, C

2004
The use of tocainide, encainide, lorcainide and flecainide for supraventricular arrhythmias.
    European heart journal, 1984, Volume: 5 Suppl B

    Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node;

1984
Effects of flecainide on electrophysiological properties of accessory pathways in the Wolff-Parkinson-White syndrome.
    European heart journal, 1983, Volume: 4, Issue:5

    Topics: Adult; Electrophysiology; Female; Flecainide; Heart Conduction System; Humans; Male; Middle Aged; Pi

1983
Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy.
    Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1994, Volume: 145, Issue:1

    Topics: Aged; Cerebellar Ataxia; Drug Interactions; Drug Therapy, Combination; Flecainide; Humans; Male; Myo

1994
Electrocardiographic case. Irregular broad complex tachycardia. Wolff-Parkinson-White syndrome with atrial flutter-fibrillation.
    Singapore medical journal, 1994, Volume: 35, Issue:6

    Topics: Atrial Fibrillation; Atrial Flutter; Diagnosis, Differential; Electrocardiography; Flecainide; Human

1994
Cardioversion of fetal tachyarrhythmia with adenosine.
    Lancet (London, England), 1994, Dec-10, Volume: 344, Issue:8937

    Topics: Adenosine; Adult; Digoxin; Female; Fetal Diseases; Flecainide; Heart Rate, Fetal; Humans; Infant, Ne

1994
Current treatment options for paroxysmal supraventricular tachycardia.
    American heart journal, 1994, Volume: 127, Issue:2

    Topics: Acute Disease; Catheter Ablation; Chronic Disease; Flecainide; Humans; Propafenone; Tachycardia, Atr

1994
ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome.
    Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Flecainide; Follow-Up Studies; Hea

1999
Prenatal diagnosis of the Wolf-Parkinson-White-syndrome by fetal magnetocardiography.
    BJOG : an international journal of obstetrics and gynaecology, 2001, Volume: 108, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Fetal Diseases; Flecainide; Humans; Magn

2001
Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age.
    Journal of the American College of Cardiology, 2002, Feb-06, Volume: 39, Issue:3

    Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Com

2002
A study of the use of flecainide acetate in the long-term management of cardiac arrhythmias.
    Pacing and clinical electrophysiology : PACE, 1990, Volume: 13, Issue:6

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Administration Schedule; Dru

1990
[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants].
    Archives francaises de pediatrie, 1991, Volume: 48, Issue:9

    Topics: Flecainide; Humans; Infant, Newborn; Male; Tachycardia, Supraventricular; Wolff-Parkinson-White Synd

1991
[Effects of intravenous flecainide acetate in patients with concealed atrioventricular pathway with supraventricular tachycardia].
    Zhonghua xin xue guan bing za zhi, 1991, Volume: 19, Issue:6

    Topics: Adult; Electrocardiography; Female; Flecainide; Humans; Injections, Intravenous; Male; Middle Aged;

1991
[Our experience with flecainide acetate in resistant arrhythmias in children. Apropos of 35 cases].
    Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Electrocardiography; Female; Flecainide; Humans; Infant; Infant

1991
Combined sotalol and flecainide given at low dosage in patients with the Wolff-Parkinson-White syndrome.
    International journal of cardiology, 1990, Volume: 26, Issue:3

    Topics: Adult; Drug Combinations; Female; Flecainide; Follow-Up Studies; Humans; Male; Refractory Period, El

1990
Opposite effects of propafenone and flecainide in a patient with reciprocating supraventricular tachycardia.
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:3

    Topics: Administration, Oral; Cardiac Pacing, Artificial; Electrocardiography; Female; Flecainide; Follow-Up

1990
Is there a genetic factor in flecainide toxicity?
    BMJ (Clinical research ed.), 1989, Jan-14, Volume: 298, Issue:6666

    Topics: Cold Temperature; Drug Storage; Flecainide; Humans; Infant, Newborn; Male; Wolff-Parkinson-White Syn

1989
Electrophysiologic effects, efficacy and tolerance of class Ic antiarrhythmic agents in Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1989, Mar-15, Volume: 63, Issue:11

    Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Drug Tolerance; Electroca

1989
Flecainide acetate for resistant arrhythmias in the young: efficacy and pharmacokinetics.
    Journal of the American College of Cardiology, 1989, Volume: 14, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Arrhythmias, Cardiac; Child; Child, Preschool; Digoxin; Ech

1989
Reversal of electrophysiologic effects of flecainide on the accessory pathway by isoproterenol in the Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1989, Jul-15, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Electrophysiology; Female; Flecainide; Follow-Up Studies; Humans; Isoproterenol;

1989
[Pharmacodynamics and pharmacokinetics of flecainide in cardiac pre-excitation of the bundle of Kent].
    Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:5

    Topics: Adult; Aged; Female; Flecainide; Heart Conduction System; Humans; Male; Middle Aged; Wolff-Parkinson

1989
[Value of transesophageal auricular stimulation for evaluating the accessory pathway and effect of treatment in Wolf-Parkinson-White syndrome].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:9

    Topics: Adult; Arrhythmias, Cardiac; Electric Stimulation; Electrocardiography; Female; Flecainide; Heart At

1989
[Syncope in a 16-year-old young man during a football match].
    Schweizerische medizinische Wochenschrift, 1986, Oct-11, Volume: 116, Issue:41

    Topics: Adolescent; Atrial Fibrillation; Flecainide; Humans; Male; Syncope; Wolff-Parkinson-White Syndrome

1986
The response of paediatric arrhythmias to intravenous and oral flecainide.
    British heart journal, 1987, Volume: 57, Issue:2

    Topics: Administration, Oral; Adolescent; Bundle of His; Child; Child, Preschool; Female; Flecainide; Heart

1987
Flecainide plasma concentrations correlated to inhibition of a bundle of Kent.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:2

    Topics: Adult; Electrocardiography; Flecainide; Heart Conduction System; Humans; Kinetics; Male; Wolff-Parki

1987
Successful use of flecainide in atrial fibrillation with rapid ventricular rate in the Wolff-Parkinson-White syndrome.
    American heart journal, 1988, Volume: 115, Issue:6

    Topics: Adult; Atrial Fibrillation; Electrocardiography; Electrophysiology; Flecainide; Heart Rate; Heart Ve

1988
[Intravenous flecainide in Wolff-Parkinson-White syndrome: a test for evaluation of the refractory period of the anomalous pathway. Comparison with ajmaline].
    Cardiologia (Rome, Italy), 1988, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Aged; Ajmaline; Child; Female; Flecainide; Heart Conduction System; Humans; Infus

1988
[Wolff-Parkinson-White syndrome and anesthesia].
    Minerva anestesiologica, 1987, Volume: 53, Issue:11

    Topics: Adult; Amiodarone; Anesthesia, General; Female; Flecainide; Humans; Propranolol; Tachycardia, Paroxy

1987
[Value of flecainide in supraventricular arrhythmias].
    Annales de cardiologie et d'angeiologie, 1986, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial F

1986
Loss of efficacy of flecainide in the Wolff-Parkinson-White syndrome after isoproterenol administration.
    European heart journal, 1985, Volume: 6, Issue:12

    Topics: Adult; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Heart Block; Heart Conductio

1985
[Effects of oral and injectable flecainide in patients with an accessory atrioventricular pathway].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78 Spec No

    Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Electrocardiography; Electrop

1985
Use of flecainide acetate for refractory junctional tachycardias in children with the Wolff-Parkinson-White syndrome.
    The American journal of cardiology, 1986, Apr-01, Volume: 57, Issue:10

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Child; Child, Preschool; Electrocardiography; Female;

1986
Evaluation of flecainide acetate in rapid atrial fibrillation complicating Wolff-Parkinson-White syndrome.
    Clinical cardiology, 1985, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Electroc

1985
Long term use of flecainide in patients with supraventricular tachycardia.
    Drugs, 1985, Volume: 29 Suppl 4

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Female; Flecainide; Humans; Male; Middle Aged; Pipe

1985
The clinical use of oral flecainide.
    Drugs, 1985, Volume: 29 Suppl 4

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Flecainide; Humans; Piperidines;

1985