flecainide and Tachycardia, Supraventricular studies

Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).

Tachycardia, Supraventricular: A generic expression for any tachycardia that originates above the BUNDLE OF HIS.

Research Excerpts

Excerpt	Relevance	Reference
"Patients with supraventricular arrhythmias have been safely and effectively treated with flecainide."	9.08	Safety and utility of flecainide acetate in the routine care of patients with supraventricular tachyarrhythmias: results of a multicenter trial. The Flecainide Supraventricular Tachycardia Study Group. ( Buxton, AE; Heilman, JM; Hopson, JR; Kienzle, MG; Nademanee, K; Rinkenberger, RL, 1996)
"In order to compare the long-term safety of flecainide and propafenone, an open label, randomized, parallel group study was performed in 335 patients with paroxysmal atrial fibrillation (n = 200) or paroxysmal supraventricular tachycardia (n = 135), and no history of heart disease."	9.08	Safety of flecainide versus propafenone for the long-term management of symptomatic paroxysmal supraventricular tachyarrhythmias. Report from the Flecainide and Propafenone Italian Study (FAPIS) Group. ( Casadei, G; Chimienti, M; Cullen, MT, 1995)
"The dose-response relations for efficacy and tolerance of the antiarrhythmic drug flecainide acetate were studied in 28 patients with paroxysmal supraventricular tachycardia (Group 1) and 45 patients with paroxysmal atrial fibrillation or flutter (Group 2)."	9.07	Flecainide acetate treatment of paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation: dose-response studies. The Flecainide Supraventricular Tachycardia Study Group. ( DaTorre, SD; Hougham, AJ; McCarville, SE; Platt, ML; Pritchett, EL, 1991)
"The aim of this review is to evaluate the available data on efficacy and safety of flecainide in all the spectrum of its indications including cardioversion of recent-onset AF, sinus rhythm maintenance in paroxysmal AF and management of ventricular tachyarrhythmias."	8.89	Flecainide acetate for the treatment of atrial and ventricular arrhythmias. ( Apostolakis, S; Breithardt, G; Fabritz, L; Kirchhof, P; Oeff, M; Tebbe, U, 2013)
"Flecainide (CAS 54143-55-4) has been associated with increased mortality in patients with ventricular dysfunction and arrhythmias."	8.81	Meta-analysis of flecainide safety in patients with supraventricular arrhythmias. ( Wehling, M, 2002)
"This report summarizes efficacy and safety data on the use of flecainide acetate for supraventricular arrhythmias."	8.78	Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias. ( Hohnloser, SH; Zabel, M, 1992)
"Flecainide is a benzenacetamide synthesised about a decade ago and only recently introduced into the treatment of arrhythmias."	8.77	[Flecainide and anti-arrhythmia therapy]. ( Croce, L; Lomuscio, A; Pozzoni, L; Romano, S, 1988)
"We retrospectively studied the clinical efficacy and safety of oral flecainide in 38 patients with symptomatic arrhythmias."	7.69	Safety and efficacy of oral flecainide acetate in patients with cardiac arrhythmias. ( Nakata, Y; Nakazato, K; Nakazato, Y; Ogura, S; Sumiyoshi, M; Yamaguchi, H; Yasuda, M, 1997)
"In a recent clinical trial, the class Ic antiarrhythmic drugs encainide and flecainide were found to be associated with an increased mortality risk in patients with new myocardial infarction and ventricular arrhythmias."	7.68	Mortality in patients treated with flecainide and encainide for supraventricular arrhythmias. ( Pritchett, EL; Wilkinson, WE, 1991)
"Four neonates with Wolff-Parkinson-White syndrome developed supraventricular tachycardia and received flecainide orally after reduction of the arrhythmia."	7.68	[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants]. ( Casasoprana, A; Denjoy, I; Jacqz-Aigrain, E; Lupoglazoff, JM, 1991)
"In order to compare the long-term safety of flecainide and propafenone, an open label, randomized, parallel group study was performed in 335 patients with paroxysmal atrial fibrillation (n = 200) or paroxysmal supraventricular tachycardia (n = 135), and no history of heart disease."	5.08	Safety of flecainide versus propafenone for the long-term management of symptomatic paroxysmal supraventricular tachyarrhythmias. Report from the Flecainide and Propafenone Italian Study (FAPIS) Group. ( Casadei, G; Chimienti, M; Cullen, MT, 1995)
"Patients with supraventricular arrhythmias have been safely and effectively treated with flecainide."	5.08	Safety and utility of flecainide acetate in the routine care of patients with supraventricular tachyarrhythmias: results of a multicenter trial. The Flecainide Supraventricular Tachycardia Study Group. ( Buxton, AE; Heilman, JM; Hopson, JR; Kienzle, MG; Nademanee, K; Rinkenberger, RL, 1996)
"The dose-response relations for efficacy and tolerance of the antiarrhythmic drug flecainide acetate were studied in 28 patients with paroxysmal supraventricular tachycardia (Group 1) and 45 patients with paroxysmal atrial fibrillation or flutter (Group 2)."	5.07	Flecainide acetate treatment of paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation: dose-response studies. The Flecainide Supraventricular Tachycardia Study Group. ( DaTorre, SD; Hougham, AJ; McCarville, SE; Platt, ML; Pritchett, EL, 1991)
"Eighty-three patients with paroxysmal supraventricular tachycardia (Wolff-Parkinson-White syndrome in 47 patients and atrioventricular nodal reentry in 36 patients) underwent electrophysiologic study before and after intravenous administration of flecainide."	5.06	Long-term efficacy and safety of flecainide for supraventricular tachycardia. ( Neuss, H; Schlepper, M, 1988)
"The aim of this review is to evaluate the available data on efficacy and safety of flecainide in all the spectrum of its indications including cardioversion of recent-onset AF, sinus rhythm maintenance in paroxysmal AF and management of ventricular tachyarrhythmias."	4.89	Flecainide acetate for the treatment of atrial and ventricular arrhythmias. ( Apostolakis, S; Breithardt, G; Fabritz, L; Kirchhof, P; Oeff, M; Tebbe, U, 2013)
"Flecainide (CAS 54143-55-4) has been associated with increased mortality in patients with ventricular dysfunction and arrhythmias."	4.81	Meta-analysis of flecainide safety in patients with supraventricular arrhythmias. ( Wehling, M, 2002)
" In the case of atrial flutters the pregnant woman is treated with sotalol administered orally and, if no sinus rhythm is obtained nor a reduced ventricular rhythm occurs, subsequently with digoxin."	4.81	[Protocols for the treatment of supraventricular tachycardias in the fetus]. ( Ambachtsheer, EB; Meijboom, EJ; Oudijk, MA; Stoutenbeek, P, 2001)
" These antiarrhythmics, prescribed to prevent atrial fibrillation (3 patients) and atrial flutter (5 patients), were flecainide in 4 cases, propafenone in 2 cases and cibenzoline and hydroquinidine respectively associated with digitoxine and propranolol."	4.79	[Supraventricular tachycardia with wide QRS complexes during Vaughan-Williams class I anti-arrhythmic treatment. Diagnostic and therapeutic implications]. ( Aouate, P; Benassar, A; Fontaine, G; Frank, R; Jacquemin, M; Laborde, JP; Tageddine, R; Tonet, J; Turlure, A, 1995)
"This report summarizes efficacy and safety data on the use of flecainide acetate for supraventricular arrhythmias."	4.78	Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias. ( Hohnloser, SH; Zabel, M, 1992)
"Flecainide is a benzenacetamide synthesised about a decade ago and only recently introduced into the treatment of arrhythmias."	4.77	[Flecainide and anti-arrhythmia therapy]. ( Croce, L; Lomuscio, A; Pozzoni, L; Romano, S, 1988)
"The use of flecainide and propafenone for medical cardioversion of atrial fibrillation (AF) and atrial flutter/intra-atrial reentrant tachycardia (IART) is well-described in adults without congenital heart disease (CHD)."	4.31	Medical cardioversion of atrial fibrillation and flutter with class IC antiarrhythmic drugs in young patients with and without congenital heart disease. ( Alexander, ME; Bezzerides, VJ; DeWitt, ES; Dionne, A; Eberly, LM; Mah, DY; O'Leary, ET; Przybylski, R; Triedman, JK; Walsh, EP, 2023)
"High-dose flecainide and digoxin combination offers effective treatment strategy in fetuses with hydrops and tachyarrhythmia with favourable outcomes."	4.12	Favourable outcome for hydrops or cardiac failure associated with fetal tachyarrhythmia: a 20-year review. ( Beattie, RB; Tunca Sahin, G; Uzun, O, 2022)
"Flecainide is a class Ic antidysrhythmic agent used to prevent and treat both ventricular and supraventricular tachycardias, including atrial fibrillation, atrioventricular nodal re-entrant tachycardia, and Wolff-Parkinson-White syndrome."	3.96	The Case of Flecainide Toxicity: What to Look for and How to Treat. ( Newson, JM; Santos, CD; Todd, BR; Walters, BL, 2020)
"Oral flecainide was successful in longer-term management of arrhythmia in 74 and 81% of patients with AV nodal and AV reentrant tachycardia, respectively, and in 83% with atrial tachycardia."	3.76	Summary of efficacy and safety of flecainide for supraventricular arrhythmias. ( Anderson, JL; Fredell, PA; Jolivette, DM, 1988)
"Flecainide is an effective therapy for supraventricular tachycardias in a twin pregnancy."	3.74	Diagnosis, treatment, observation and outcome of fetal supraventricular tachycardia in a twin pregnancy. ( Gronemeyer, D; Hatzmann, W; Reinhard, J; Schiermeier, S; van Leeuwen, P, 2008)
"We retrospectively studied the clinical efficacy and safety of oral flecainide in 38 patients with symptomatic arrhythmias."	3.69	Safety and efficacy of oral flecainide acetate in patients with cardiac arrhythmias. ( Nakata, Y; Nakazato, K; Nakazato, Y; Ogura, S; Sumiyoshi, M; Yamaguchi, H; Yasuda, M, 1997)
"We report a case of fetal supraventricular tachycardia with intra uterine cardiac failure, treated with oral administration of flecainide acetate (Flecaine) to the mother."	3.69	[Flecaine: drug of choice for supraventricular tachycardias with anasarca. A case report]. ( Barjot, P; Febbraro, W; Hamel, P; Iselin, M; Lindet, Y; Muller, G, 1997)
"A 73 year-old patient with Wolff-Parkinson-White syndrome and paroxysmic supraventricular tachycardia developed an acute reversible encephalopathy within 15 days of initiation of flecainide."	3.69	Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy. ( Ghika, J; Goy, JJ; Naegeli, C; Regli, F, 1994)
"A 46 year-old woman with Wolff-Parkinson-White syndrome (postero-septal accessory pathway), symptomatic for recurrent episodes of nonsustained paroxismal supraventricular tachycardia (PSVT), was empirically treated with propafenone (600 mg/day)."	3.68	Opposite effects of propafenone and flecainide in a patient with reciprocating supraventricular tachycardia. ( Calvi, V; di Bona, G; Manzoli, U; Montenero, AS; Natale, A; Santarelli, P, 1990)
"Four neonates with Wolff-Parkinson-White syndrome developed supraventricular tachycardia and received flecainide orally after reduction of the arrhythmia."	3.68	[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants]. ( Casasoprana, A; Denjoy, I; Jacqz-Aigrain, E; Lupoglazoff, JM, 1991)
"In a recent clinical trial, the class Ic antiarrhythmic drugs encainide and flecainide were found to be associated with an increased mortality risk in patients with new myocardial infarction and ventricular arrhythmias."	3.68	Mortality in patients treated with flecainide and encainide for supraventricular arrhythmias. ( Pritchett, EL; Wilkinson, WE, 1991)
" Both the intravenous efficacy and the oral efficacy of 2 class IC antiarrhythmic drugs, encainide and flecainide, were studied in 16 patients with atrial ectopic tachycardia and in 3 patients with junctional ectopic tachycardia, using exercise testing, 24-hour long-term electrocardiography and programmed electrical stimulation."	3.67	Encainide versus flecainide for chronic atrial and junctional ectopic tachycardia. ( Duckeck, W; Kuck, KH; Kunze, KP; Schlüter, M, 1988)
"We report on a 46-year-old woman with ventricular tachycardia and ventricular fibrillation after starting antiarrhythmic drug therapy with flecainide."	3.67	[Arrhythmogenic effect of flecainide--treatment with i.v. magnesium]. ( Jung, W; Kamradt, T; Lüderitz, B; Manz, M; Mletzko, R; Vogel, F, 1989)
"Standardized treatment of fetal tachyarrhythmia has not been established."	2.90	Antenatal Therapy for Fetal Supraventricular Tachyarrhythmias: Multicenter Trial. ( Hagiwara, A; Hamasaki, T; Horigome, H; Ikeda, T; Inamura, N; Kato, H; Katsuragi, S; Kawataki, M; Maeno, Y; Miyoshi, T; Nii, M; Sago, H; Sakaguchi, H; Shimizu, W; Shiraishi, I; Taketazu, M; Ueda, K; Yamamoto, H; Yasukochi, S; Yoda, H, 2019)
"Flecainide is a first-line antiarrhythmic drug used to treat atrial arrhythmias and/or supraventricular tachycardia in those without coronary artery disease or structural heart disease."	2.72	Perioperative Management of Flecainide: A Problem-Based Learning Discussion. ( Acker, L; Bova Campbell, K; Bronshteyn, YS; Naglee, C; Taicher, B, 2021)
" There were no deaths and no reports of major proarrhythmic events or other major adverse effects."	2.68	Efficacy and safety of long-term oral flecainide acetate in patients with responsive supraventricular tachycardia. ( Hellestrand, KJ, 1996)
"Oral flecainide acetate was administered to 34 patients with documented symptomatic paroxysmal supraventricular tachycardia (PSVT) with a double-blind, placebo-controlled, 8-week crossover trial design."	2.67	Flecainide acetate prevents recurrence of symptomatic paroxysmal supraventricular tachycardia. The Flecainide Supraventricular Tachycardia Study Group. ( Alpert, BL; Anderson, JL; Bhandari, AK; Gilbert, EM; Hawkinson, RW; Henthorn, RW; Pritchett, EL; Waldo, AL, 1991)
"Flecainide has been shown to be effective in short-term, controlled studies for prevention of paroxysmal supraventricular tachycardia (SVT) and paroxysmal atrial fibrillation (AF)."	2.67	Flecainide acetate for paroxysmal supraventricular tachyarrhythmias. The Flecainide Supraventricular Tachycardia Study Group. ( Anderson, JL; Fox, TL; Guarnieri, T; Maser, MJ; Platt, ML; Pritchett, EL, 1994)
" Only 3 (5%) of 66 patients discontinued therapy due to possible noncardiac adverse effects."	2.67	Long-term safety and efficacy of flecainide in the treatment of supraventricular tachyarrhythmias: the United States experience. The Flecainide Supraventricular Tachyarrhythmia Investigators. ( Anderson, JL, 1992)
"With flecainide, nine cases were reported at varying times after initiation of therapy, from in-hospital to 8 months."	2.39	Inpatient versus outpatient initiation of antiarrhythmic drug therapy for patients with supraventricular tachycardia. ( Prystowsky, EN, 1994)
"Fetal supraventricular tachycardia is a relatively uncommon cardiac rhythm abnormality which is often associated with adverse perinatal outcomes if untreated."	1.62	Management of Fetal Supraventricular Tachycardia: Case Series from a Tertiary Perinatal Cardiac Center. ( Broom, E; Gardener, G; Gooi, A; Kostner, K; Kumar, S; Lee-Tannock, A; Petersen, S; Thomas, JT; Ward, C, 2021)
"Supraventricular tachycardia is the most common fetal tachyarrhythmia and if persistent often associated with fetal hydrops which can cause intrauterine and neonatal death."	1.56	Refractory Fetal Supraventricular Tachycardia with Hydrops Successfully Converted by Intraperitoneal Flecainide in the Fetus: A Case Report. ( Ekelund, CK; Gembruch, U; Harmsen, L; Jaeggi, E; Jensen, LN; Nørgaard, LN; Petersen, OB; Sundberg, K; Vedel, C; Vejlstrup, N, 2020)
"Flecainide was discontinued at 31 weeks' gestation due to elevated liver enzymes."	1.56	Complete resolution of arrhythmia-induced hydrops fetalis in utero. ( Alapati, S; Dhuka, S; Kauffman, RP; Narayanan, M, 2020)
"Flecainide acetate is a Vaughan-Williams class IC antiarrhythmic drug prescribed for the treatment of supraventricular arrhythmias."	1.56	Complete Heart Block Secondary to Flecainide Toxicity: Is It Time for CYP2D6 Genotype Testing? ( Abdul Haium, AA; Choo, TLJ; Lee, JH; Poh, BH, 2020)
"Flecainide was used in 47 patients and amiodarone in 27 patients."	1.51	A comparison of oral flecainide and amiodarone for the treatment of recurrent supraventricular tachycardia in children. ( Bar-Cohen, Y; Hill, AC; Silka, MJ, 2019)
" Propranolol is a common choice though it is dosed every 6-8 h."	1.46	Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children. ( Bradley, DJ; Caruthers, R; LaPage, MJ; von Alvensleben, JC, 2017)
"Flecainide was more effective than digoxin, especially when hydrops was present."	1.43	Flecainide versus digoxin for fetal supraventricular tachycardia: Comparison of two drug treatment protocols. ( Dominguez, TE; Janoušek, J; Marek, J; Škovránek, J; Sridharan, S; Sullivan, I; Tomek, V; Wolfenden, J; Yates, R, 2016)
"Fetal tachyarrhythmia can lead to fetal hydrops due to heart failure."	1.43	High-dose flecainide is the most effective treatment of fetal supraventricular tachycardia. ( Berg, C; Geipel, A; Gembruch, U; Gottschalk, I; Herberg, U; Strizek, B, 2016)
"Transplacental flecainide is an established therapy for fetal supraventricular tachycardia (SVT), but there is a paucity of data regarding the dose-response relationship."	1.40	Correlation of maternal flecainide concentrations and therapeutic effect in fetal supraventricular tachycardia. ( Andrews, RE; Callaghan, N; Miller, O; Rosenthal, E; Sharland, GK; Simpson, JM; Vigneswaran, TV, 2014)
"Supraventricular tachycardia is uncommon in pregnancy."	1.40	Management of labour and delivery in a woman with refractory supraventricular tachycardia. ( Dennis, AT; Gerstman, MD, 2014)
"Flecainide is a class IC antiarrhythmic agent, used frequently in all age groups for the treatment of tachyarrhythmias."	1.38	Decreased milk drinking causing flecainide toxicity in an older child. ( Barton, C; Hawcutt, DB; Mangat, J; Thompson, B, 2012)
"Flecainide and digoxin were superior to sotalol in converting SVT to a normal rhythm and in slowing both AF and SVT to better-tolerated ventricular rates and therefore might be considered first to treat significant fetal tachyarrhythmia."	1.37	Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study. ( Api, O; Blom, NA; Carvalho, JS; Clur, SA; De Groot, E; Jaeggi, ET; Manlhiot, C; McCrindle, BW; Rammeloo, L; Ryan, G, 2011)
"Flecainide for the treatment of supraventricular tachycardia (SVT) in newborns is still controversial because of its potentially severe proarrhythmic effects."	1.35	Flecainide as first-line treatment for supraventricular tachycardia in newborns. ( Bonanomi, C; Centola, M; Colli, AM; Danzi, GB; Ferlini, M; Galli, MA; Ravaglia, R; Salice, P; Salvini, L, 2009)
" We conclude, therefore, that dosing of the drug should be always done with caution, and in case of suspected haemolysis plasma levels should be repeated with a new blood sample."	1.34	Haemolysis alters plasma flecainide levels in newborn infants. ( Cano, A; Escrig, R; Sáenz, P; Sánchez, A; Tudela, BF; Vento, M, 2007)
"To examine the effect of CYP2D6 genotype on the pharmacokinetics of flecainide, we conducted a population pharmacokinetic analysis of the data collected during routine therapeutic drug monitoring of Japanese patients with supraventricular tachyarrhythmia."	1.33	Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia. ( Doki, K; Homma, M; Kohda, Y; Kuga, K; Kusano, K; Watanabe, S; Yamaguchi, I, 2006)
"Flecainide was prescribed with a median posology of 150 mg per day, mostly as LP form (64%)."	1.33	[Flecainide acetate utilisation review among general practitioners and hospital or office-based cardiologists in France. Obepine: observational study of flecainide]. ( Danchin, N; Jaillon, P; Le Heuzey, JY; Liard, F; Lièvre, M, 2006)
"Supraventricular tachycardia is the most common clinically significant fetal tachycardia."	1.32	Fetal supraventricular tachycardia diagnosed and treated at twenty-four weeks of gestation and after birth: a case report. ( Annunziata, A; Calabrò, R; Cardaropoli, D; D'Alto, M; Pacileo, G; Paladini, D; Romeo, E; Russo, MG; Sarubbi, B, 2004)
"Treatment with digoxin and flecainide was successful; the heart rate returned to sinus rhythm within one day, and fetal hydrops resolved within 8 days of treatment."	1.32	Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report. ( Anteby, EY; Hamani, Y; Porat, S; Yagel, S, 2003)
"Flecainide use can cause the absence of accelerations and poor variability in the FHR."	1.29	The effect of flecainide acetate on fetal heart rate variability: a case report. ( de Jong, CL; de Vries, JI; van Geijn, HP; van Gelder-Hasker, MR, 1995)
"Flecainide was effective in restoring sinus rhythm in all non-hydropic fetuses where digoxin treatment failed, and in 43 per cent of hydropic fetuses."	1.29	The efficacy of flecainide versus digoxin in the management of fetal supraventricular tachycardia. ( Den Hollander, NS; Frohn-Mulder, IM; Hess, J; Stewart, PA; Witsenburg, M; Wladimiroff, JW, 1995)
"Three patients with fetal hydrops died."	1.29	Management outcome and follow-up of fetal tachycardia. ( Brenner, JI; Copel, JA; Kleinman, CS; Meijboom, EJ; Stoutenbeek, P; van Engelen, AD; Weijtens, O, 1994)
"The diagnosis of ventricular tachycardia is difficult, often requiring endocavitary investigation to obtain proof."	1.29	[Tachycardia with wide QRS. Limitations of electrocardiographic criteria in patients treated with anti-arrhythmia agents]. ( Dupuis, JM; Le Davay, M; Merheb, M; Tadeï, A; Tran, P; Victor, J, 1994)
" Pharmacokinetic variables were calculated--median terminal half life 7."	1.28	Paediatric use of flecainide in supraventricular tachycardia: clinical efficacy and pharmacokinetics. ( Bhamra, R; Haga, P; Holt, DW; Johnston, A; Rowland, E; Shinebourne, EA; Till, JA; Ward, DE, 1989)
"Supraventricular tachycardia is relatively common in pregnancy, and is related to the normal physiologic changes of the cardiovascular system in the gravid state."	1.28	Supraventricular tachycardia resistant to treatment in a pregnant woman. ( Hulkower, S; Kostic, B; Treakle, K, 1992)
"Propafenone was administered to 32 patients, with positive results in 15 (46."	1.28	Long-term follow-up of patients with inducible supraventricular tachycardia treated with flecainide or propafenone: therapy guided by transesophageal electropharmacologic testing. ( Bertoldi, A; Dallago, M; Del Greco, M; Furlanello, F; Guarnerio, M; Inama, G; Vergara, G, 1992)
" Daily flecainide dosage was 200 (100-400) mg."	1.28	Antiarrhythmic treatment with flecainide (Tambocor). Clinical experience from 107 patients. ( Frandsen, F; Mickley, H; Møller, M; Pless, P, 1990)
"Propafenone was tested in 13 patients (43."	1.28	[Electropharmacological test with class-I C drugs in paroxysmal supraventricular re-entrant tachycardia: is a negative result with a drug predictive of the ineffectiveness of other drugs of the same class?]. ( Braito, G; Furlanello, F; Guarnerio, M; Inama, G; Vergara, G, 1991)
"The fetus required no further treatment in pregnancy or at follow up."	1.28	Intermittent fetal tachycardia and fetal hydrops. ( James, DK; Martin, R; Smoleniec, JS, 1991)
"In 65% of the patients there was no recurrence during a follow-up period of 11 +/- 10 months."	1.28	Flecainide acetate in the treatment of supraventricular tachycardias: value of programmed electrical stimulation for long-term prognosis. ( Crijns, HJ; Lie, KI; van Gilst, WH; van Wijk, LM; Wesseling, H, 1989)
" Adverse effects were associated with larger dosage and atrial flutter or atrial reentrant tachycardia."	1.27	Flecainide acetate for conversion of acute supraventricular tachycardia to sinus rhythm. ( Crozier, IG; Ikram, H; Kenealy, M; Levy, L, 1987)
"Flecainide was successful in preventing recurrences of the tachycardia by eliminating slow pathway conduction during long-term follow-up."	1.27	Paroxysmal nonreentrant supraventricular tachycardia due to simultaneous fast and slow pathway conduction in dual atrioventricular node pathways. ( Kim, SS; Lal, R; Ruffy, R, 1987)
"Thus flecainide is an highly effective and well tolerated drug for the control of PSVT in infancy."	1.27	[Electrophysiological effects and clinical efficacy of flecainide in childhood patients with supraventricular reciprocating paroxysmal tachycardia]. ( Cavallaro, C; D'Onofrio, A; Della Gatta, O; Marsico, F; Musto, A; Musto, B, 1987)
"Flecainide was administered to other patients during spontaneous episodes of tachyarrhythmias."	1.27	[Treatment of recurrent supraventricular tachyarrhythmias with flecainide or a flecainide and amiodarone combination]. ( Capestro, F; Ciampani, N; Costantini, C; Fratadocchi, GB; Mazzanti, M; Molini, E; Purcaro, A, 1987)
" It allows a reduction in the dosage of amiodarone when both drugs are combined."	1.27	Long term evaluation of flecainide acetate in supraventricular tachyarrhythmias. ( Mary-Rabine, L; Telerman, M, 1988)
"Flecainide was administered during SVT to 9 patients with atrial flutter, 11 with atrial fibrillation, 7 with atrial tachycardia, 38 with AV reentrant tachycardia and 34 with AV nodal reentrant tachycardia."	1.27	Intravenous flecainide acetate for supraventricular tachycardias. ( Hellestrand, KJ, 1988)
"Flecainide acetate was administered to 19 patients who had inducible sustained orthodromic atrioventricular reentrant tachycardia."	1.27	Flecainide acetate for treatment of bypass tract mediated reentrant tachycardia. ( Kim, SS; Ruffy, R; Zee-Cheng, CS, 1988)
"Encainide was completely effective in 54% (22 of 41 study patients) and partially effective in an additional 24% (10 of 41 patients), when combined with propranolol or verapamil."	1.27	Encainide for resistant supraventricular tachycardia in children: follow-up report. ( Garson, A; Gothing, C; Moak, JP; Smith, RT; Strasburger, JF, 1988)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (20.35)	18.7374
1990's	66 (38.37)	18.2507
2000's	30 (17.44)	29.6817
2010's	29 (16.86)	24.3611
2020's	12 (6.98)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Safety Assessment for Sotalol Protocol in Outpatient Unit[NCT05418036]			Phase 4	110 participants (Anticipated)	Interventional	2020-10-26	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Sotalol as an effective adjunct therapy in the management of supraventricular tachycardia induced fetal hydrops fetalis. Journal of neonatal-perinatal medicine, 2020, Volume: 13, Issue:2 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Female; Fetal Diseases; Flecainid	2020
Perioperative Management of Flecainide: A Problem-Based Learning Discussion. A&A practice, 2021, Apr-01, Volume: 15, Issue:4 Topics: Anti-Arrhythmia Agents; Atrial Flutter; Flecainide; Humans; Problem-Based Learning; Tachycardia, Sup	2021
Is antiarrhythmic therapy safe in twin pregnancies? Acta paediatrica (Oslo, Norway : 1992), 2019, Volume: 108, Issue:9 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Preg	2019
Flecainide acetate for the treatment of atrial and ventricular arrhythmias. Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Flecainide; Humans; Prac	2013
Meta-analysis of flecainide safety in patients with supraventricular arrhythmias. Arzneimittel-Forschung, 2002, Volume: 52, Issue:7 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomegaly; Female; Flecainide; Heart V	2002
Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials. The Journal of thoracic and cardiovascular surgery, 2005, Volume: 129, Issue:5 Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial F	2005
Inpatient versus outpatient initiation of antiarrhythmic drug therapy for patients with supraventricular tachycardia. Clinical cardiology, 1994, Volume: 17, Issue:9 Suppl 2 Topics: Ambulatory Care; Anti-Arrhythmia Agents; Cardiomyopathies; Flecainide; Hospitalization; Humans; Prop	1994
[Tachycardias: considerations in childhood in the 90s]. Anales espanoles de pediatria, 1993, Volume: 39, Issue:6 Topics: Adenosine; Adolescent; Adult; Amiodarone; Atrial Flutter; Child; Child, Preschool; Electrocardiograp	1993
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy. European heart journal, 1993, Volume: 14 Suppl E Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Fle	1993
[Supraventricular tachycardia with wide QRS complexes during Vaughan-Williams class I anti-arrhythmic treatment. Diagnostic and therapeutic implications]. Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Th	1995
[Protocols for the treatment of supraventricular tachycardias in the fetus]. Nederlands tijdschrift voor geneeskunde, 2001, Jun-23, Volume: 145, Issue:25 Topics: Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Drug Therapy, Combination; Fema	2001
Short- and long-term efficacy and safety of flecainide acetate for supraventricular arrhythmias. The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Flecainide; Humans; Meta-Analysis as Topi	1992
Supraventricular tachycardia: diagnosis and current acute management. Archives of disease in childhood, 1991, Volume: 66, Issue:5 Topics: Adenosine; Electric Countershock; Electrocardiography; Flecainide; Humans; Infant; Infant, Newborn;	1991
New antiarrhythmic drugs. II. Flecainide. Pediatric cardiology, 1990, Volume: 11, Issue:3 Topics: Child; Electrocardiography; Flecainide; Heart Ventricles; Humans; Tachycardia; Tachycardia, Supraven	1990
[Flecainide and anti-arrhythmia therapy]. Minerva medica, 1988, Volume: 79, Issue:3 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Electrocardiography; Flecainide; Heart Ventricles; Humans	1988
Summary of efficacy and safety of flecainide for supraventricular arrhythmias. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Atrial Fibrillation; Atrial Flutter; Clinical Trials as Topic; Flecainide; Humans; Tachycardia, Supr	1988
[Clinical pharmacology of flecainide]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1988, Nov-01, Volume: 41, Issue:21 Topics: Clinical Trials as Topic; Flecainide; Humans; Tachycardia, Supraventricular	1988

Article	Year
Antenatal Therapy for Fetal Supraventricular Tachyarrhythmias: Multicenter Trial. Journal of the American College of Cardiology, 2019, 08-20, Volume: 74, Issue:7 Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Atrial Flutter; Cesarean Section; Digoxin; Fema	2019
Three-month lower-dose flecainide after catheter ablation of atrial fibrillation. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2014, Volume: 16, Issue:8 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Drug Administration Schedule;	2014
Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia. European journal of clinical pharmacology, 2007, Volume: 63, Issue:10 Topics: Adult; Aged; Anti-Arrhythmia Agents; Asian People; Chromatography, High Pressure Liquid; Cross-Secti	2007
Oral flecainide, sotalol, and verapamil for the termination of paroxysmal supraventricular tachycardia. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:7 Pt 1 Topics: Administration, Oral; Adult; Cardiac Pacing, Artificial; Female; Flecainide; Humans; Male; Middle Ag	1993
Effects of flecainide on exercise hemodynamics and electrocardiography in patients without structural heart disease. Clinical cardiology, 1995, Volume: 18, Issue:3 Topics: Atrial Fibrillation; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; E	1995
Flecainide acetate for paroxysmal supraventricular tachyarrhythmias. The Flecainide Supraventricular Tachycardia Study Group. The American journal of cardiology, 1994, Sep-15, Volume: 74, Issue:6 Topics: Adult; Aged; Confounding Factors, Epidemiologic; Female; Flecainide; Humans; Male; Middle Aged; Tach	1994
Safety and utility of flecainide acetate in the routine care of patients with supraventricular tachyarrhythmias: results of a multicenter trial. The Flecainide Supraventricular Tachycardia Study Group. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmia	1996
Efficacy and safety of long-term oral flecainide acetate in patients with responsive supraventricular tachycardia. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; A	1996
A randomized comparison of flecainide versus verapamil in paroxysmal supraventricular tachycardia. The Flecainide Multicenter Investigators Group. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide;	1996
Safety of flecainide versus propafenone for the long-term management of symptomatic paroxysmal supraventricular tachyarrhythmias. Report from the Flecainide and Propafenone Italian Study (FAPIS) Group. European heart journal, 1995, Volume: 16, Issue:12 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Dose-Res	1995
Efficacy and safety of out-of-hospital self-administered single-dose oral drug treatment in the management of infrequent, well-tolerated paroxysmal supraventricular tachycardia. Journal of the American College of Cardiology, 2001, Volume: 37, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Diltiazem; D	2001
Clinical and pharmacologic study of fetal supraventricular tachyarrhythmias. The Journal of pediatrics, 1992, Volume: 121, Issue:4 Topics: Digoxin; Drug Therapy, Combination; Fetal Diseases; Flecainide; Humans; Prospective Studies; Retrosp	1992
Long-term safety and efficacy of flecainide in the treatment of supraventricular tachyarrhythmias: the United States experience. The Flecainide Supraventricular Tachyarrhythmia Investigators. The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5 Topics: Atrial Fibrillation; Drug Evaluation; Drug Tolerance; Female; Flecainide; Follow-Up Studies; Humans;	1992
[Value of intravenous flecainide in electro-induced supraventricular arrhythmia. Apropos of 37 cases]. Annales de cardiologie et d'angeiologie, 1992, Volume: 41, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Electric Stimulation; Female; Flecainide; Humans; Injections, Intrav	1992
Flecainide acetate prevents recurrence of symptomatic paroxysmal supraventricular tachycardia. The Flecainide Supraventricular Tachycardia Study Group. Circulation, 1991, Volume: 83, Issue:1 Topics: Administration, Oral; Double-Blind Method; Drug Administration Schedule; Female; Flecainide; Humans;	1991
Flecainide acetate for long-term prevention of paroxysmal supraventricular tachyarrhythmias. Circulation, 1991, Volume: 83, Issue:1 Topics: Flecainide; Humans; Research Design; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Time Fa	1991
Flecainide acetate treatment of paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation: dose-response studies. The Flecainide Supraventricular Tachycardia Study Group. Journal of the American College of Cardiology, 1991, Volume: 17, Issue:2 Topics: Adult; Atrial Fibrillation; Atrial Flutter; Dose-Response Relationship, Drug; Double-Blind Method; F	1991
Treatment of fetal supraventricular tachycardia with flecainide acetate after digoxin failure. American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:3 Topics: Adult; Digoxin; Female; Fetal Diseases; Flecainide; Humans; Pregnancy; Tachycardia, Supraventricular	1991
Efficacy and safety of class IC antiarrhythmic agents for the treatment of coexisting supraventricular and ventricular tachycardia. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Electrocardi	1988
Long-term efficacy and safety of flecainide for supraventricular tachycardia. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Cardiac Pacing, Artificial; Clinical Trials as Topic; Electrocardiography; Electrophysiology; Flecai	1988
Summary of efficacy and safety of flecainide for supraventricular arrhythmias. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Atrial Fibrillation; Atrial Flutter; Clinical Trials as Topic; Flecainide; Humans; Tachycardia, Supr	1988
[Clinical pharmacology of flecainide]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1988, Nov-01, Volume: 41, Issue:21 Topics: Clinical Trials as Topic; Flecainide; Humans; Tachycardia, Supraventricular	1988

Article	Year
Toxic Effects of Flecainide in a Patient With Kidney Failure and Tachyarrhythmia. JAMA internal medicine, 2021, 11-01, Volume: 181, Issue:11 Topics: Aged; Atrial Flutter; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Flecainide;	2021
Favourable outcome for hydrops or cardiac failure associated with fetal tachyarrhythmia: a 20-year review. Cardiology in the young, 2022, Volume: 32, Issue:7 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cesarean Section; Digoxin; Female; Fetal Diseases; Fle	2022
Management of Fetal Supraventricular Tachycardia: Case Series from a Tertiary Perinatal Cardiac Center. Fetal diagnosis and therapy, 2021, Volume: 48, Issue:11-12 Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Retr	2021
Triple Antiarrhythmic Therapy in Newborns with Refractory Atrioventricular Reentrant Tachycardia. Pediatric cardiology, 2023, Volume: 44, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Flecainide; Humans; Infant; Infant, Newborn; Propranolol; Tachyc	2023
Medical cardioversion of atrial fibrillation and flutter with class IC antiarrhythmic drugs in young patients with and without congenital heart disease. Journal of cardiovascular electrophysiology, 2023, Volume: 34, Issue:12 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Electric Countershoc	2023
Predictability in Fetal Supraventricular Tachycardia Management. Journal of the American College of Cardiology, 2019, 08-20, Volume: 74, Issue:7 Topics: Female; Flecainide; Humans; Pregnancy; Prenatal Care; Tachycardia, Supraventricular	2019
The Case of Flecainide Toxicity: What to Look for and How to Treat. The Journal of emergency medicine, 2020, Volume: 59, Issue:2 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Humans; Middle	2020
Complete Heart Block Secondary to Flecainide Toxicity: Is It Time for CYP2D6 Genotype Testing? Pediatrics, 2020, Volume: 146, Issue:1 Topics: Cytochrome P-450 CYP2D6; Electrocardiography; Flecainide; Genotype; Heart Block; Humans; Infant, New	2020
Refractory Fetal Supraventricular Tachycardia with Hydrops Successfully Converted by Intraperitoneal Flecainide in the Fetus: A Case Report. Fetal diagnosis and therapy, 2020, Volume: 47, Issue:9 Topics: Adult; Anti-Arrhythmia Agents; Female; Fetal Therapies; Flecainide; Humans; Hydrops Fetalis; Pregnan	2020
Complete resolution of arrhythmia-induced hydrops fetalis in utero. BMJ case reports, 2020, Oct-10, Volume: 13, Issue:10 Topics: Anti-Arrhythmia Agents; Cesarean Section; Digoxin; Echocardiography; Female; Fetal Therapies; Flecai	2020
Supraventricular tachycardias in the first year of life: what is the best pharmacological treatment? 24 years of experience in a single centre. BMC cardiovascular disorders, 2021, 03-15, Volume: 21, Issue:1 Topics: Action Potentials; Adrenergic beta-Antagonists; Age Factors; Anti-Arrhythmia Agents; Digoxin; Drug T	2021
Antenatal antiarrhythmic treatment for fetal tachyarrhythmias: a study protocol for a prospective multicentre trial. BMJ open, 2017, Aug-29, Volume: 7, Issue:8 Topics: Anti-Arrhythmia Agents; Atrial Flutter; Child Development; Child, Preschool; Digoxin; Drug Therapy,	2017
Neonatal complex arrhythmias possibly related to a TTN mutation. Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:3 Topics: Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Connectin; Electrocardiography; Fetal Monit	2017
A comparison of oral flecainide and amiodarone for the treatment of recurrent supraventricular tachycardia in children. Pacing and clinical electrophysiology : PACE, 2019, Volume: 42, Issue:6 Topics: Administration, Oral; Adolescent; Amiodarone; Anti-Arrhythmia Agents; Child; Child, Preschool; Femal	2019
Management of idiopathic giant dilatation of the right atrium with subsequent atrial tachycardia. Archives of gynecology and obstetrics, 2013, Volume: 288, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Echocardiography; Female; Fetal Diseases; Flecainide; Heart	2013
SCN5A promoter haplotype affects the therapeutic range for serum flecainide concentration in Asian patients. Pharmacogenetics and genomics, 2013, Volume: 23, Issue:7 Topics: Aged; Anti-Arrhythmia Agents; Asian People; Female; Flecainide; Haplotypes; Homozygote; Humans; Male	2013
Management of labour and delivery in a woman with refractory supraventricular tachycardia. International journal of obstetric anesthesia, 2014, Volume: 23, Issue:1 Topics: Adult; Amides; Amnion; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Epidural; Anes	2014
Correlation of maternal flecainide concentrations and therapeutic effect in fetal supraventricular tachycardia. Heart rhythm, 2014, Volume: 11, Issue:11 Topics: Adult; Algorithms; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Echocardiography; Femal	2014
Use of maternal flecainide concentration in management of fetal supraventricular tachycardia: a step in the right direction. Heart rhythm, 2014, Volume: 11, Issue:11 Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Pregnancy; Tachycardia, Supraven	2014
Serum flecainide S/R ratio reflects the CYP2D6 genotype and changes in CYP2D6 activity. Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:4 Topics: Anti-Arrhythmia Agents; Bepridil; Bignoniaceae; Cytochrome P-450 CYP2D6; DNA, Complementary; Female;	2015
The use of flecainide in critical neonates and infants with incessant supraventricular tachycardias. Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2015, Volume: 43, Issue:7 Topics: Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Drug Therapy, Combination; Female; Flecainide	2015
High-dose flecainide is the most effective treatment of fetal supraventricular tachycardia. Heart rhythm, 2016, Volume: 13, Issue:6 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Heart Rate, Fetal; Humans; Hydrops Fetal	2016
Variation in Antiarrhythmic Management of Infants Hospitalized with Supraventricular Tachycardia: A Multi-Institutional Analysis. Pediatric cardiology, 2016, Volume: 37, Issue:5 Topics: Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Humans; Infant; Infant, Newborn; Male; Retrospe	2016
Flecainide vs digoxin for fetal supraventricular tachycardia: Comparison of 2 drug protocols. Heart rhythm, 2016, Volume: 13, Issue:9 Topics: Anti-Arrhythmia Agents; Digoxin; Fetal Diseases; Flecainide; Humans; Tachycardia; Tachycardia, Supra	2016
β1-Adrenergic receptor Arg389Gly polymorphism affects the antiarrhythmic efficacy of flecainide in patients with coadministration of β-blockers. Pharmacogenetics and genomics, 2016, Volume: 26, Issue:10 Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Drug Therapy, Combination; Female; Flecai	2016
Flecainide versus digoxin for fetal supraventricular tachycardia: Comparison of two drug treatment protocols. Heart rhythm, 2016, Volume: 13, Issue:9 Topics: Administration, Intravenous; Administration, Oral; Adult; Anti-Arrhythmia Agents; Clinical Protocols	2016
Nadolol for Treatment of Supraventricular Tachycardia in Infants and Young Children. Pediatric cardiology, 2017, Volume: 38, Issue:3 Topics: Age of Onset; Anti-Arrhythmia Agents; Databases, Factual; Female; Flecainide; Humans; Infant; Infant	2017
Proarrhythmic Antiarrhythmic. Texas Heart Institute journal, 2016, Volume: 43, Issue:6 Topics: Action Potentials; Anti-Arrhythmia Agents; Atrial Flutter; Atrioventricular Node; Catheter Ablation;	2016
Flecainide as first-line treatment for fetal supraventricular tachycardia. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2018, Volume: 31, Issue:4 Topics: Adult; Anti-Arrhythmia Agents; Echocardiography; Female; Fetal Diseases; Fetal Heart; Flecainide; Ge	2018
Diagnosis, treatment, observation and outcome of fetal supraventricular tachycardia in a twin pregnancy. Fetal diagnosis and therapy, 2008, Volume: 24, Issue:4 Topics: Adrenergic beta-Agonists; Adult; Anti-Arrhythmia Agents; Echocardiography; Female; Fenoterol; Fetal	2008
ECGs in the ED. Pediatric emergency care, 2008, Volume: 24, Issue:11 Topics: Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Emergency Service, Hospital; Fleca	2008
An enhancement of coronary blood flow in a fetus with supraventricular tachycardia. Prenatal diagnosis, 2009, Volume: 29, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Female; Fetal Membranes, Premature Rupture; Flecainide; Humans; Infan	2009
Flecainide as first-line treatment for supraventricular tachycardia in newborns. Journal of cardiovascular medicine (Hagerstown, Md.), 2009, Volume: 10, Issue:5 Topics: Administration, Oral; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography, Ambula	2009
Effects of CYP2D6 genotypes on age-related change of flecainide metabolism: involvement of CYP1A2-mediated metabolism. British journal of clinical pharmacology, 2009, Volume: 68, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cytochrome P-450 CYP1A2; Cytoch	2009
Successful use of a rapid response team in the pediatric oncology outpatient setting. Joint Commission journal on quality and patient safety, 2010, Volume: 36, Issue:1 Topics: Adolescent; Anti-Arrhythmia Agents; Antineoplastic Agents; Bone Neoplasms; Flecainide; Hospital Rapi	2010
Incessant tachycardia following posteroseptal pathway ablation: a pseudo-r' or pseudo-pseudo-r' wave in V1? Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:11 Topics: Accessory Atrioventricular Bundle; Adult; Catheter Ablation; Digoxin; Electrocardiography; Flecainid	2010
Comparison of transplacental treatment of fetal supraventricular tachyarrhythmias with digoxin, flecainide, and sotalol: results of a nonrandomized multicenter study. Circulation, 2011, Oct-18, Volume: 124, Issue:16 Topics: Anti-Arrhythmia Agents; Digoxin; Drug Evaluation; Female; Fetal Diseases; Fetal Therapies; Flecainid	2011
Rapid control of foetal supraventricular tachycardia with digoxin and flecainide combination treatment. Cardiology in the young, 2012, Volume: 22, Issue:4 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Drug Therapy, Combination; Echoc	2012
Decreased milk drinking causing flecainide toxicity in an older child. BMJ case reports, 2012, Jun-21, Volume: 2012 Topics: Animals; Anti-Arrhythmia Agents; Apnea; Child; Child, Preschool; Confusion; Drinking Behavior; Drug	2012
[Supraventricular extrasystole after cardioversion with amiodarone]. Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:28-29 Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Premature Complex	2012
Fetal supraventricular tachycardia: a role for amiodarone as second-line therapy? Prenatal diagnosis, 2003, Volume: 23, Issue:2 Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Flecainide; Hydrops Fetalis;	2003
Neonatal ECG changes caused by supratherapeutic flecainide following treatment for fetal supraventricular tachycardia. Heart (British Cardiac Society), 2003, Volume: 89, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Female; Fetal Diseases; Flecainid	2003
Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2003, Volume: 21, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Gestational Age; Humans; Hydrops Fetalis	2003
[Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases]. Journal de gynecologie, obstetrique et biologie de la reproduction, 2003, Volume: 32, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Echocardiography; F	2003
Neonatal flecainide toxicity following supraventricular tachycardia treatment. The Annals of pharmacotherapy, 2003, Volume: 37, Issue:9 Topics: Anti-Arrhythmia Agents; Dobutamine; Enoximone; Female; Fetal Diseases; Flecainide; Humans; Infant, N	2003
Flecainide induced ventricular fibrillation in a neonate. Heart (British Cardiac Society), 2003, Volume: 89, Issue:10 Topics: Anti-Arrhythmia Agents; Fatal Outcome; Flecainide; Humans; Infant, Newborn; Tachycardia, Supraventri	2003
Fetal supraventricular tachycardia diagnosed and treated at twenty-four weeks of gestation and after birth: a case report. Italian heart journal : official journal of the Italian Federation of Cardiology, 2004, Volume: 5, Issue:10 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Fetal Distress; Flecainide; Gestational Age; Humans;	2004
[Combination therapy for fetal supraventricular tachycardia with flecainide and digoxin]. Zeitschrift fur Geburtshilfe und Neonatologie, 2005, Volume: 209, Issue:1 Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Drug Combinations; Female; Fetal Distress; Flecainide; Human	2005
[Fetal supraventricular tachyarrhythmias refractory to initial therapy]. Medicina, 2005, Volume: 65, Issue:2 Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Female; Fetal Diseases; Flecainide; Humans; Male	2005
[Flecainide acetate utilisation review among general practitioners and hospital or office-based cardiologists in France. Obepine: observational study of flecainide]. Annales de cardiologie et d'angeiologie, 2006, Volume: 55, Issue:3 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Output, Low; Cardiology; Coronary Disease	2006
Effect of CYP2D6 genotype on flecainide pharmacokinetics in Japanese patients with supraventricular tachyarrhythmia. European journal of clinical pharmacology, 2006, Volume: 62, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents; Asian People; Cytochrome P-450 CYP2D6; Female	2006
Fetal and maternal magnetocardiography during flecainide therapy for supraventricular tachycardia. Obstetrics and gynecology, 2006, Volume: 108, Issue:3 Pt 2 Topics: Anti-Arrhythmia Agents; Diseases in Twins; Electrocardiography; Female; Fetal Diseases; Flecainide;	2006
Haemolysis alters plasma flecainide levels in newborn infants. Acta paediatrica (Oslo, Norway : 1992), 2007, Volume: 96, Issue:3 Topics: Anti-Arrhythmia Agents; Flecainide; Gas Chromatography-Mass Spectrometry; Hemolysis; Humans; Infant,	2007
Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy. Emergency medicine Australasia : EMA, 2007, Volume: 19, Issue:2 Topics: Adult; Anti-Arrhythmia Agents; Cardiovascular Diseases; Charcoal; Drug Overdose; Electrocardiography	2007
Acute reversible ataxo-myoclonic encephalopathy with flecainide therapy. Schweizer Archiv fur Neurologie und Psychiatrie (Zurich, Switzerland : 1985), 1994, Volume: 145, Issue:1 Topics: Aged; Cerebellar Ataxia; Drug Interactions; Drug Therapy, Combination; Flecainide; Humans; Male; Myo	1994
The effect of flecainide acetate on fetal heart rate variability: a case report. Obstetrics and gynecology, 1995, Volume: 86, Issue:4 Pt 2 Topics: Adult; Female; Fetal Diseases; Flecainide; Heart Rate, Fetal; Humans; Pregnancy; Tachycardia, Suprav	1995
Direct fetal administration of adenosine for the termination of incessant supraventricular tachycardia. Obstetrics and gynecology, 1995, Volume: 85, Issue:5 Pt 2 Topics: Adenosine; Digoxin; Female; Fetal Death; Flecainide; Gestational Age; Heart Rate; Humans; Hydrops Fe	1995
Flecainide and amiodarone: combined therapy for refractory tachyarrhythmias in infancy. Journal of the American College of Cardiology, 1995, Volume: 25, Issue:5 Topics: Amiodarone; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Flecainide; Follow-U	1995
Management outcome and follow-up of fetal tachycardia. Journal of the American College of Cardiology, 1994, Nov-01, Volume: 24, Issue:5 Topics: Atrial Flutter; Digoxin; Echocardiography; Female; Fetal Diseases; Fetal Heart; Flecainide; Follow-U	1994
Cardioversion of fetal tachyarrhythmia with adenosine. Lancet (London, England), 1994, Dec-10, Volume: 344, Issue:8937 Topics: Adenosine; Adult; Digoxin; Female; Fetal Diseases; Flecainide; Heart Rate, Fetal; Humans; Infant, Ne	1994
[Tachycardia with wide QRS. Limitations of electrocardiographic criteria in patients treated with anti-arrhythmia agents]. Annales de cardiologie et d'angeiologie, 1994, Volume: 43, Issue:5 Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Electrocardiography; Flecainide; Humans; Male; Midd	1994
Treatment with flecainide for symptomatic and refractory tachyarrhythmias in children. Acta paediatrica Japonica : Overseas edition, 1994, Volume: 36, Issue:1 Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Female; Flecainide; Humans; Infant; Injec	1994
Current treatment options for paroxysmal supraventricular tachycardia. American heart journal, 1994, Volume: 127, Issue:2 Topics: Acute Disease; Catheter Ablation; Chronic Disease; Flecainide; Humans; Propafenone; Tachycardia, Atr	1994
Is exercise testing safe in patients treated with flecainide for atrial arrhythmia? American heart journal, 1993, Volume: 126, Issue:1 Topics: Contraindications; Exercise Test; Flecainide; Humans; Quinidine; Tachycardia, Supraventricular	1993
A symposium: Supraventricular Arrhythmias: Update 1995. Boston, Massachusetts, May 6, 1995. The American journal of cardiology, 1996, Jan-25, Volume: 77, Issue:3 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Flecainide; Humans; Tachycardia, Supraventricular	1996
Effect of flecainide on atrial and ventricular refractoriness and conduction in patients with normal left ventricle. Implications for possible antiarrhythmic and proarrhythmic mechanisms. European heart journal, 1995, Volume: 16, Issue:12 Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Dose	1995
[Role of a "bystander" concealed accessory pathway in the response to verapamil and flecainide treatment in a patient with nodal reentry tachycardia]. Giornale italiano di cardiologia, 1996, Volume: 26, Issue:4 Topics: Anti-Arrhythmia Agents; Child; Echocardiography; Electrocardiography, Ambulatory; Flecainide; Heart	1996
The efficacy of flecainide versus digoxin in the management of fetal supraventricular tachycardia. Prenatal diagnosis, 1995, Volume: 15, Issue:13 Topics: Anti-Arrhythmia Agents; Digoxin; Edema; Female; Fetal Diseases; Flecainide; Humans; Pregnancy; Retro	1995
[Flecaine: drug of choice for supraventricular tachycardias with anasarca. A case report]. Journal de gynecologie, obstetrique et biologie de la reproduction, 1997, Volume: 26, Issue:1 Topics: Anti-Arrhythmia Agents; Electrocardiography; Female; Fetal Diseases; Flecainide; Heart Failure; Huma	1997
[Fetal supraventricular tachycardia with anasarca complicating benign extrasystole: treatment with flecainide. Apropos of a case]. Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:3 Topics: Anti-Arrhythmia Agents; Atrial Premature Complexes; Dose-Response Relationship, Drug; Drug Administr	1997
Safety and efficacy of oral flecainide acetate in patients with cardiac arrhythmias. Japanese heart journal, 1997, Volume: 38, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child;	1997
[European protocol for the management of fetal supraventricular tachycardia. European Association of Pediatric Cardiology]. Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:5 Topics: Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Fetal Death	1997
Flecainide against fetal supraventricular tachycardia complicated by hydrops fetalis. Acta obstetricia et gynecologica Scandinavica, 1998, Volume: 77, Issue:3 Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Follow-Up Studies; Humans; Hydrops Fetal	1998
Transplacental flecainide therapy for fetal supraventricular tachycardia in a twin pregnancy. The Australian & New Zealand journal of obstetrics & gynaecology, 1999, Volume: 39, Issue:1 Topics: Adult; Anti-Arrhythmia Agents; Diseases in Twins; Ethics, Medical; Female; Fetal Diseases; Flecainid	1999
Digoxin, flecainide, and amiodarone transfer across the placenta and the effects of an elevated umbilical venous pressure on the transfer rate. Therapeutic drug monitoring, 2000, Volume: 22, Issue:5 Topics: Amiodarone; Anti-Arrhythmia Agents; Area Under Curve; Digoxin; Female; Fetal Diseases; Flecainide; H	2000
Guidelines for the use of flecainide in patients with supraventricular arrhythmias. The New Zealand medical journal, 2000, Oct-13, Volume: 113, Issue:1119 Topics: Anti-Arrhythmia Agents; Contraindications; Drug Monitoring; Flecainide; Humans; Patient Selection; P	2000
Supraventricular tachycardia with hydrops in a 27-week premature baby. International journal of clinical practice, 2001, Volume: 55, Issue:8 Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Hydrops Fetalis; Infan	2001
Flecainide and sotalol: a new combination therapy for refractory supraventricular tachycardia in children <1 year of age. Journal of the American College of Cardiology, 2002, Feb-06, Volume: 39, Issue:3 Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Com	2002
Flecainide in the intrauterine treatment of fetal supraventricular tachycardia. Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2002, Volume: 19, Issue:2 Topics: Anti-Arrhythmia Agents; Cardiotocography; Digoxin; Female; Fetal Diseases; Flecainide; Humans; Hydro	2002
Diffuse infiltrative lung disease associated with flecainide. Report of two cases. Respiration; international review of thoracic diseases, 2002, Volume: 69, Issue:2 Topics: Aged; Anti-Arrhythmia Agents; Bronchoalveolar Lavage Fluid; Flecainide; Humans; Lung Diseases; Male;	2002
Death of child with supraventricular tachycardia. Lancet (London, England), 1992, Jun-27, Volume: 339, Issue:8809 Topics: Child, Preschool; Flecainide; Humans; Male; Malpractice; Physician's Role; Tachycardia, Supraventric	1992
A symposium: Use of flecainide for the treatment of supraventricular arrhythmias. Amsterdam, The Netherlands, August 17, 1991. The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5 Topics: Flecainide; Humans; Tachycardia, Supraventricular	1992
Supraventricular tachycardia resistant to treatment in a pregnant woman. The Journal of family practice, 1992, Volume: 35, Issue:5 Topics: Adult; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electric Countershock; Female; Flecainide;	1992
Long-term follow-up of patients with inducible supraventricular tachycardia treated with flecainide or propafenone: therapy guided by transesophageal electropharmacologic testing. The American journal of cardiology, 1992, Aug-20, Volume: 70, Issue:5 Topics: Adult; Cardiac Pacing, Artificial; Female; Flecainide; Follow-Up Studies; Humans; Male; Propafenone;	1992
[Drug therapy in supraventricular arrhythmia]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Apr-28, Volume: 81, Issue:18 Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Flecainide; Humans; Quinidine; Tachycardia, Supraventri	1992
Treatment of fetal supraventricular tachycardia with flecainide acetate after digoxin failure. American journal of obstetrics and gynecology, 1992, Volume: 166, Issue:6 Pt 1 Topics: Adult; Digoxin; Female; Fetal Diseases; Flecainide; Humans; Pregnancy; Tachycardia, Supraventricular	1992
Flecainide for supraventricular tachyarrhythmias. The Medical letter on drugs and therapeutics, 1992, Jul-24, Volume: 34, Issue:875 Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Flecainide; Humans; Tachycardia, Paroxysmal; Tachycardia,	1992
Correlation of symptoms with occurrence of paroxysmal supraventricular tachycardia or atrial fibrillation: a transtelephonic monitoring study. The Flecainide Supraventricular Tachycardia Study Group. American heart journal, 1992, Volume: 124, Issue:2 Topics: Atrial Fibrillation; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Predictive	1992
A study of the use of flecainide acetate in the long-term management of cardiac arrhythmias. Pacing and clinical electrophysiology : PACE, 1990, Volume: 13, Issue:6 Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Administration Schedule; Dru	1990
Antiarrhythmic treatment with flecainide (Tambocor). Clinical experience from 107 patients. Acta cardiologica, 1990, Volume: 45, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Atrial Flutte	1990
Flecainide therapy in patients treated for supraventricular tachycardia with near normal left ventricular function. American heart journal, 1992, Volume: 123, Issue:2 Topics: Atrial Fibrillation; Atrial Flutter; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Age	1992
Intermittent fetal tachycardia and fetal hydrops. Archives of disease in childhood, 1991, Volume: 66, Issue:10 Spec No Topics: Adult; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Tachycardia, Supraven	1991
[Use of flecainide in the preventive treatment of tachycardia crisis of Wolff-Parkinson-White syndrome in 4 newborn infants]. Archives francaises de pediatrie, 1991, Volume: 48, Issue:9 Topics: Flecainide; Humans; Infant, Newborn; Male; Tachycardia, Supraventricular; Wolff-Parkinson-White Synd	1991
[Effects of intravenous flecainide acetate in patients with concealed atrioventricular pathway with supraventricular tachycardia]. Zhonghua xin xue guan bing za zhi, 1991, Volume: 19, Issue:6 Topics: Adult; Electrocardiography; Female; Flecainide; Humans; Injections, Intravenous; Male; Middle Aged;	1991
Fetal supraventricular tachycardia treated with flecainide acetate. The Journal of pediatrics, 1991, Volume: 118, Issue:2 Topics: Adult; Female; Fetal Diseases; Fetal Heart; Flecainide; Humans; Infant, Newborn; Male; Pregnancy; Ta	1991
Mortality in patients treated with flecainide and encainide for supraventricular arrhythmias. The American journal of cardiology, 1991, May-01, Volume: 67, Issue:11 Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Female; Flecainide;	1991
The acute effects of flecainide in the swine heart failing from incessant supraventricular tachycardia. American heart journal, 1991, Volume: 121, Issue:6 Pt 1 Topics: Animals; Cardiac Output, Low; Cardiac Pacing, Artificial; Electrophysiology; Flecainide; Heart Atria	1991
Proarrhythmia, cardiac arrest and death in young patients receiving encainide and flecainide. The Pediatric Electrophysiology Group. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:2 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Death, Sudden; Encainide; Flecainide;	1991
[Electropharmacological test with class-I C drugs in paroxysmal supraventricular re-entrant tachycardia: is a negative result with a drug predictive of the ineffectiveness of other drugs of the same class?]. Giornale italiano di cardiologia, 1991, Volume: 21, Issue:2 Topics: Adolescent; Adult; Cardiac Pacing, Artificial; Drug Evaluation; Electrocardiography; Female; Flecain	1991
[Our experience with flecainide acetate in resistant arrhythmias in children. Apropos of 35 cases]. Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:5 Topics: Adolescent; Child; Child, Preschool; Electrocardiography; Female; Flecainide; Humans; Infant; Infant	1991
Flecainide toxicity in a neonate with supraventricular tachycardia. Heart & lung : the journal of critical care, 1991, Volume: 20, Issue:6 Topics: Electrocardiography; Flecainide; Heart Block; Humans; Infant, Newborn; Male; Tachycardia, Supraventr	1991
Possible atrial proarrhythmic effects of class 1C antiarrhythmic drugs. The American journal of cardiology, 1990, Aug-01, Volume: 66, Issue:3 Topics: Aged; Anilides; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Encainide; Female; Flec	1990
Dangerous recurrence of arrhythmia following withdrawal of flecainide. International journal of cardiology, 1990, Volume: 28, Issue:2 Topics: Child, Preschool; Double Outlet Right Ventricle; Flecainide; Humans; Male; Substance Withdrawal Synd	1990
Opposite effects of propafenone and flecainide in a patient with reciprocating supraventricular tachycardia. Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:3 Topics: Administration, Oral; Cardiac Pacing, Artificial; Electrocardiography; Female; Flecainide; Follow-Up	1990
[His bundle block 2:1 during paroxysmal supraventricular tachycardia involving an occult accessory atrio-His pathway]. Giornale italiano di cardiologia, 1990, Volume: 20, Issue:12 Topics: Bundle of His; Electrocardiography; Female; Flecainide; Heart Block; Heart Conduction System; Humans	1990
Flecainide acetate in the treatment of supraventricular tachycardias: value of programmed electrical stimulation for long-term prognosis. American heart journal, 1989, Volume: 117, Issue:2 Topics: Adult; Aged; Cardiac Pacing, Artificial; Electrophysiology; Flecainide; Follow-Up Studies; Humans; M	1989
Pseudocardiomyopathy secondary to chronic incessant supraventricular tachycardia. Archives of disease in childhood, 1989, Volume: 64, Issue:3 Topics: Cardiomyopathy, Dilated; Child; Chronic Disease; Flecainide; Humans; Male; Tachycardia, Supraventric	1989
Paediatric use of flecainide in supraventricular tachycardia: clinical efficacy and pharmacokinetics. British heart journal, 1989, Volume: 62, Issue:2 Topics: Administration, Oral; Adolescent; Age Factors; Child; Child, Preschool; Female; Flecainide; Half-Lif	1989
[Flecainide acetate in the acute and medium-term prophylactic treatment of 2 cases of ectopic atrial tachycardia]. Cardiologia (Rome, Italy), 1989, Volume: 34, Issue:6 Topics: Aged; Echocardiography; Electrocardiography; Female; Flecainide; Humans; Middle Aged; Tachycardia, E	1989
[Arrhythmogenic effect of flecainide--treatment with i.v. magnesium]. Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:9 Topics: Electrocardiography; Female; Flecainide; Heart Valve Prosthesis; Humans; Magnesium; Middle Aged; Mit	1989
Efficacy of flecainide in pacing-induced sustained ventricular tachyarrhythmias: correlation to clinical parameters and tachycardia-characteristics. European heart journal, 1989, Volume: 10, Issue:10 Topics: Adult; Aged; Cardiac Pacing, Artificial; Drug Evaluation; Electrophysiology; Female; Flecainide; Hum	1989
Use of flecainide in children. Lancet (London, England), 1989, Aug-05, Volume: 2, Issue:8658 Topics: Child; Child, Preschool; Flecainide; Humans; Infant; Tachycardia, Atrioventricular Nodal Reentry; Ta	1989
[Treatment of junctional tachycardia with high doses of flecainide in infants]. Presse medicale (Paris, France : 1983), 1988, Sep-17, Volume: 17, Issue:31 Topics: Flecainide; Humans; Infant; Male; Tachycardia, Ectopic Junctional; Tachycardia, Supraventricular	1988
Evaluation of the efficacy of flecainide acetate in the treatment of ventricular premature contractions. Postgraduate medical journal, 1986, Volume: 62, Issue:723 Topics: Flecainide; Humans; Tachycardia, Supraventricular	1986
Flecainide acetate for conversion of acute supraventricular tachycardia to sinus rhythm. The American journal of cardiology, 1987, Mar-01, Volume: 59, Issue:6 Topics: Acute Disease; Adolescent; Adult; Aged; Female; Flecainide; Heart Rate; Humans; Infusions, Intraveno	1987
Treatment of refractory supraventricular arrhythmias with flecainide acetate. Archives of disease in childhood, 1987, Volume: 62, Issue:3 Topics: Administration, Oral; Adolescent; Arrhythmias, Cardiac; Child; Child, Preschool; Female; Flecainide;	1987
Paroxysmal nonreentrant supraventricular tachycardia due to simultaneous fast and slow pathway conduction in dual atrioventricular node pathways. Journal of the American College of Cardiology, 1987, Volume: 10, Issue:2 Topics: Atrioventricular Node; Atropine; Cardiac Pacing, Artificial; Electrocardiography; Female; Flecainide	1987
[Electrophysiological effects and clinical efficacy of flecainide in childhood patients with supraventricular reciprocating paroxysmal tachycardia]. Giornale italiano di cardiologia, 1987, Volume: 17, Issue:5 Topics: Adolescent; Child; Child, Preschool; Electrocardiography; Female; Flecainide; Heart Conduction Syste	1987
[Treatment of recurrent supraventricular tachyarrhythmias with flecainide or a flecainide and amiodarone combination]. Giornale italiano di cardiologia, 1987, Volume: 17, Issue:8 Topics: Administration, Oral; Adult; Aged; Amiodarone; Drug Therapy, Combination; Electrocardiography; Femal	1987
Long term evaluation of flecainide acetate in supraventricular tachyarrhythmias. Acta cardiologica, 1988, Volume: 43, Issue:1 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Electrocardiography; Fema	1988
[Flecainide and paroxysmal supraventricular tachycardia in the operating room]. Schweizerische medizinische Wochenschrift, 1988, Jun-18, Volume: 118, Issue:24 Topics: Anesthesia, General; Electrocardiography; Female; Flecainide; Humans; Middle Aged; Reoperation; Surg	1988
Electrophysiologic effects and clinical efficacy of flecainide in children with recurrent paroxysmal supraventricular tachycardia. The American journal of cardiology, 1988, Aug-01, Volume: 62, Issue:4 Topics: Child; Electrophysiology; Female; Flecainide; Heart Conduction System; Humans; Male; Tachycardia, Pa	1988
Ventricular Wenckebach after intravenous therapy with class I antiarrhythmic agents. International journal of cardiology, 1988, Volume: 20, Issue:1 Topics: Adult; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Female; Flecainide; Heart Block;	1988
International Symposium on Supraventricular Arrhythmias: Focus on Flecainide. October 23-26, 1987, Paradise Island, Nassau, Bahamas. Proceedings. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Flecainide; Humans; Tachycardia, Supraventricular	1988
Intravenous flecainide acetate for supraventricular tachycardias. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Electrocardiography; Electro	1988
Flecainide acetate for treatment of bypass tract mediated reentrant tachycardia. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Adult; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female; Flecainide; Follo	1988
Flecainide for supraventricular tachycardia in children. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Adolescent; Child; Flecainide; Follow-Up Studies; Humans; Tachycardia, Supraventricular; Time Factor	1988
Electrophysiologic and clinical effects of flecainide for recurrent paroxysmal supraventricular tachycardia. The American journal of cardiology, 1988, Sep-15, Volume: 62, Issue:9 Topics: Adolescent; Adult; Aged; Cardiac Pacing, Artificial; Electrophysiology; Female; Flecainide; Humans;	1988
Flecainide for supraventricular and ventricular arrhythmias in children and young adults. The American journal of cardiology, 1988, Oct-01, Volume: 62, Issue:10 Pt 1 Topics: Adolescent; Adult; Child; Child, Preschool; Echocardiography; Electrocardiography; Flecainide; Human	1988
[Wolff-Parkinson-White syndrome and anesthesia]. Minerva anestesiologica, 1987, Volume: 53, Issue:11 Topics: Adult; Amiodarone; Anesthesia, General; Female; Flecainide; Humans; Propranolol; Tachycardia, Paroxy	1987
Flecainide acetate in the treatment of resistant supraventricular arrhythmias. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1988, Dec-03, Volume: 74, Issue:11 Topics: Adolescent; Adult; Aged; Child; Depression, Chemical; Electrocardiography; Female; Flecainide; Heart	1988
Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment. The American journal of cardiology, 1988, Dec-01, Volume: 62, Issue:17 Topics: Aged; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Tachy	1988
Encainide versus flecainide for chronic atrial and junctional ectopic tachycardia. The American journal of cardiology, 1988, Dec-20, Volume: 62, Issue:19 Topics: Administration, Oral; Adolescent; Adult; Aged; Anilides; Anti-Arrhythmia Agents; Chronic Disease; El	1988
Encainide for resistant supraventricular tachycardia in children: follow-up report. The American journal of cardiology, 1988, Dec-20, Volume: 62, Issue:19 Topics: Administration, Oral; Adolescent; Anilides; Anti-Arrhythmia Agents; Child; Child, Preschool; Drug Th	1988
[Electrophysiologic effects of intravenous flecainide in intranodal junctional tachycardia in 30 patients]. Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81, Issue:12 Topics: Adolescent; Adult; Aged; Electrocardiography; Electrophysiology; Female; Flecainide; Heart Conductio	1988

flecainide and Tachycardia, Supraventricular

Research Excerpts

Research

Studies (172)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Liu, JS	1
Fan, EH	1
Tunca Sahin, G	1
Beattie, RB	1
Uzun, O	2
Broom, E	1
Thomas, JT	1
Petersen, S	1
Gooi, A	1
Ward, C	1
Gardener, G	1
Kostner, K	1
Lee-Tannock, A	1
Kumar, S	1
Ciriello, GD	1
Colonna, D	1
Papaccioli, G	1
Correra, A	1
Romeo, E	2
Palladino, MT	1
Cioppa, ND	1
Russo, MG	2
Sarubbi, B	2
Przybylski, R	1
Eberly, LM	1
Alexander, ME	1
Bezzerides, VJ	1
DeWitt, ES	1
Dionne, A	1
Mah, DY	1
Triedman, JK	1
Walsh, EP	1
O'Leary, ET	1
Miyoshi, T	2
Maeno, Y	2
Hamasaki, T	2
Inamura, N	2
Yasukochi, S	2
Kawataki, M	2
Horigome, H	2
Yoda, H	2
Taketazu, M	2
Nii, M	2
Hagiwara, A	2
Kato, H	2
Shimizu, W	3
Shiraishi, I	2
Sakaguchi, H	2
Ueda, K	2
Katsuragi, S	2
Yamamoto, H	2
Sago, H	2
Ikeda, T	2
Strasburger, JF	2
Refaat, M	1
El Dick, J	1
Sabra, M	1
Bitar, F	1
Tayeh, C	1
Abutaqa, M	1
Arabi, M	1
Newson, JM	1
Santos, CD	1
Walters, BL	1
Todd, BR	1
Poh, BH	1
Lee, JH	1
Abdul Haium, AA	1
Choo, TLJ	1
Vedel, C	1
Vejlstrup, N	1
Jensen, LN	1
Ekelund, CK	1
Nørgaard, LN	1
Harmsen, L	1
Petersen, OB	1
Jaeggi, E	1
Gembruch, U	3
Sundberg, K	1
Narayanan, M	1
Dhuka, S	1
Alapati, S	1
Kauffman, RP	1
Capponi, G	1
Belli, G	1
Giovannini, M	1
Remaschi, G	1
Brambilla, A	1
Vannuccini, F	1
Favilli, S	1
Porcedda, G	1
De Simone, L	1
Acker, L	1
Bova Campbell, K	1
Naglee, C	1
Taicher, B	1
Bronshteyn, YS	1
Shozu, M	1
Evans, WN	1
Acherman, RJ	1
Law, IH	1
Von Bergen, NH	1
Samson, RA	1
Restrepo, H	1
Hill, AC	1
Silka, MJ	1
Bar-Cohen, Y	1
Gesuete, V	1
Fantasia, I	1
Lo Bello, L	1
Rizzante, E	1
D'Agata Mottolese, B	1
Stampalija, T	1
Enzensberger, C	1
Kreymborg, KG	1
Valeske, K	1
Apitz, C	1
Akintürk, H	1
Schranz, D	1
Axt-Fliedner, R	1
Doki, K	6
Homma, M	6
Kuga, K	6
Aonuma, K	5
Kohda, Y	4
Dennis, AT	1
Gerstman, MD	1
Hayashi, M	1
Miyauchi, Y	1
Iwasaki, YK	1
Yodogawa, K	1
Tsuboi, I	1
Uetake, S	1
Hayashi, H	1
Takahashi, K	1
Vigneswaran, TV	1
Callaghan, N	1
Andrews, RE	1
Miller, O	1
Rosenthal, E	2
Sharland, GK	1
Simpson, JM	1
Cuneo, BF	1
Benson, DW	2
Sekiguchi, Y	2
Ergül, Y	1
Özyılmaz, İ	1
Saygı, M	1
Tola, HT	1
Akdeniz, C	1
Tuzcu, V	1
Strizek, B	1
Berg, C	1
Gottschalk, I	1
Herberg, U	1
Geipel, A	2
Guerrier, K	1
Shamszad, P	1
Czosek, RJ	1
Spar, DS	1
Knilans, TK	1
Anderson, JB	1
Van Hare, GF	1
Sridharan, S	1
Sullivan, I	1
Tomek, V	1
Wolfenden, J	1
Škovránek, J	1
Yates, R	1
Janoušek, J	1
Dominguez, TE	1
Marek, J	1
von Alvensleben, JC	1
LaPage, MJ	1
Caruthers, R	1
Bradley, DJ	1
Pollet, M	1
Saeed, M	1
Ekiz, A	1
Kaya, B	1
Bornaun, H	1
Acar, DK	1
Avci, ME	1
Bestel, A	1
Yildirim, G	1
Schiermeier, S	1
van Leeuwen, P	1
Reinhard, J	1
Gronemeyer, D	1
Hatzmann, W	1
Tanel, RE	1
Uerpairojkit, B	1
Manotaya, S	1
Tanawattanacharoen, S	1
Prechawat, S	1
Charoenvidhya, D	1
Ferlini, M	1
Colli, AM	1
Bonanomi, C	1
Salvini, L	1
Galli, MA	1
Salice, P	1
Ravaglia, R	1
Centola, M	1
Danzi, GB	1
Avent, Y	1
Johnson, S	1
Henderson, N	1
Wilder, K	1
Cresswell, J	1
Elbahlawan, L	1
Lim, HS	1
Kuchar, D	1
Walker, B	1
Thorburn, C	1
Subbiah, R	1
Jaeggi, ET	1
Carvalho, JS	1
De Groot, E	1
Api, O	1
Clur, SA	1
Rammeloo, L	1
McCrindle, BW	1
Ryan, G	1
Manlhiot, C	1
Blom, NA	1
Babaoglu, K	1
Sinha, A	1
Massias, S	1
Beattie, B	1
Thompson, B	1
Mangat, J	1
Barton, C	1
Hawcutt, DB	1
Meinertz, T	1
Apostolakis, S	1
Oeff, M	1
Tebbe, U	1
Fabritz, L	1
Breithardt, G	2
Kirchhof, P	1
Wehling, M	1
Jouannic, JM	2
Delahaye, S	2
Fermont, L	2
Le Bidois, J	2
Villain, E	2
Dumez, Y	2
Dommergues, M	2
Rasheed, A	1
Simpson, J	1
Porat, S	1
Anteby, EY	1
Hamani, Y	1
Yagel, S	1
Hall, CM	1
Ward Platt, MP	1
Ackland, F	1
Singh, R	1
Thayyil, S	1
D'Alto, M	1
Cardaropoli, D	1
Paladini, D	1
Pacileo, G	1
Annunziata, A	1
Calabrò, R	1
Anderer, G	1
Hellmeyer, L	1
Tekesin, I	1
Schmidt, S	1
Sedrakyan, A	1
Treasure, T	1
Browne, J	1
Krumholz, H	1
Sharpin, C	1
van der Meulen, J	1
Malvino, E	1
Bruno, MC	1
Gallo, JP	1
Medrano, JC	1
Ferrante, D	1
Liard, F	1
Le Heuzey, JY	1
Jaillon, P	1
Lièvre, M	1
Danchin, N	1
Kusano, K	1
Watanabe, S	1
Yamaguchi, I	2
Campbell, JQ	1
Best, TH	1
Eswaran, H	1
Lowery, CL	1
Vento, M	1
Tudela, BF	1
Escrig, R	1
Sáenz, P	1
Sánchez, A	1
Cano, A	1
Devin, R	1
Garrett, P	1
Anstey, C	1
Sakai, S	1
Ghika, J	1
Goy, JJ	1
Naegeli, C	1
Regli, F	1
van Gelder-Hasker, MR	1
de Jong, CL	1
de Vries, JI	1
van Geijn, HP	1
Hamer, AW	1
Strathmore, N	1
Vohra, JK	1
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