flecainide has been researched along with Renal Insufficiency in 5 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Five case reports are presented pertaining to diabetic ketoacidosis in an adult who was not known to suffer from diabetes and in presence of multiple psychotropic substances; fatal flecainide intoxication in a poor metabolizer also presenting an impaired renal function; diabetic ketoacidosis showing severe postmortem changes; primary aldosteronism presented with intracranial hemorrhage and hypothermia showing severe postmortem changes." | 3.78 | Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports. ( Augsburger, M; Lesta, Mdel M; Mangin, P; Palmiere, C; Sabatasso, S; Sporkert, F, 2012) |
| " Recently a new method has been proposed to determine absolute bioavailability in the absence of intravenous dose." | 1.30 | Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical view. ( Mahmood, I, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, JS | 1 |
| Fan, EH | 1 |
| Sohn, JT | 1 |
| Palmiere, C | 1 |
| Lesta, Mdel M | 1 |
| Sabatasso, S | 1 |
| Mangin, P | 1 |
| Augsburger, M | 1 |
| Sporkert, F | 1 |
| Evers, J | 1 |
| Eichelbaum, M | 1 |
| Kroemer, HK | 1 |
| Mahmood, I | 1 |
5 other studies available for flecainide and Renal Insufficiency
| Article | Year |
|---|---|
Toxic Effects of Flecainide in a Patient With Kidney Failure and Tachyarrhythmia.
Topics: Aged; Atrial Flutter; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Flecainide; | 2021 |
Treatment of flecainide intoxication with a lipid emulsion.
Topics: Flecainide; Humans; Lipids; Pacemaker, Artificial; Renal Insufficiency; Shock | 2019 |
Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Adult; Aged; Anti-Arrhythmia Agents; Benzodiazepines; Biomarkers; | 2012 |
Unpredictability of flecainide plasma concentrations in patients with renal failure: relationship to side effects and sudden death?
Topics: Aged; Death, Sudden; Dose-Response Relationship, Drug; Female; Flecainide; Humans; Male; Middle Aged | 1994 |
Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical view.
Topics: Acebutolol; Administration, Oral; Adult; Aged; Amiloride; Anti-Arrhythmia Agents; Anti-Infective Age | 1997 |