flecainide has been researched along with Pre-Excitation Syndromes in 5 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Pre-Excitation Syndromes: A group of conditions in which HEART VENTRICLE activation by the atrial impulse is faster than the normal impulse conduction from the SINOATRIAL NODE. In these pre-excitation syndromes, atrial impulses often bypass the ATRIOVENTRICULAR NODE delay and travel via ACCESSORY CONDUCTING PATHWAYS connecting the atrium directly to the BUNDLE OF HIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen consecutive patients who had ventricular preexcitation complicated by atrial fibrillation or flutter were treated with intravenous flecainide acetate after treatment with as many as 5 unsuccessful trial regimens with other drugs." | 3.67 | Treatment of atrial tachyarrhythmias and preexcitation syndrome with flecainide acetate. ( Kim, SS; Ruffy, R; Smith, P, 1988) |
| "There were 63 deaths/resuscitated cardiac arrests in the active treatment (encainide/flecainide) group and 26 in the placebo group." | 2.67 | Prevalence, characteristics and significance of ventricular premature complexes and ventricular tachycardia detected by 24-hour continuous electrocardiographic recording in the Cardiac Arrhythmia Suppression Trial. CAST Investigators. ( Denes, P; Gillis, AM; Kammerling, JM; Pawitan, Y; Salerno, DM; Wilhelmsen, L, 1991) |
| "Flecainide acetate is a new class 1 c antiarrhythmic drug." | 2.37 | Flecainide: a new antiarrhythmic drug. ( Baur, HR; Mueller, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morady, F | 1 |
| Manz, M | 1 |
| Lüderitz, B | 1 |
| Denes, P | 1 |
| Gillis, AM | 1 |
| Pawitan, Y | 1 |
| Kammerling, JM | 1 |
| Wilhelmsen, L | 1 |
| Salerno, DM | 1 |
| Kim, SS | 1 |
| Smith, P | 1 |
| Ruffy, R | 1 |
| Mueller, RA | 1 |
| Baur, HR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000526] | Phase 3 | 0 participants | Interventional | 1986-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for flecainide and Pre-Excitation Syndromes
| Article | Year |
|---|---|
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Fle | 1993 |
Flecainide: a new antiarrhythmic drug.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Flecainide; Hemo | 1986 |
1 trial available for flecainide and Pre-Excitation Syndromes
| Article | Year |
|---|---|
Prevalence, characteristics and significance of ventricular premature complexes and ventricular tachycardia detected by 24-hour continuous electrocardiographic recording in the Cardiac Arrhythmia Suppression Trial. CAST Investigators.
Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cross-Sectional Studies; Electric Countershock | 1991 |
2 other studies available for flecainide and Pre-Excitation Syndromes
| Article | Year |
|---|---|
Wide QRS complexes during atrial fibrillation: what is the mechanism?
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrophysiology; Flecainide; Humans; Male; Middle Age | 2004 |
Treatment of atrial tachyarrhythmias and preexcitation syndrome with flecainide acetate.
Topics: Adult; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Electrocardiography; Electro | 1988 |