flecainide has been researched along with Poisoning in 10 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 8.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 4.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| " Five case reports are presented pertaining to diabetic ketoacidosis in an adult who was not known to suffer from diabetes and in presence of multiple psychotropic substances; fatal flecainide intoxication in a poor metabolizer also presenting an impaired renal function; diabetic ketoacidosis showing severe postmortem changes; primary aldosteronism presented with intracranial hemorrhage and hypothermia showing severe postmortem changes." | 3.78 | Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports. ( Augsburger, M; Lesta, Mdel M; Mangin, P; Palmiere, C; Sabatasso, S; Sporkert, F, 2012) |
| "Flecainide is a lipophilic anti-arrhythmic with a significant cardiotoxic profile, with blockade of sodium and potassium channels causing arrhythmias and shock in severe toxicity." | 1.39 | Hypertonic sodium bicarbonate versus intravenous lipid emulsion in a rabbit model of intravenous flecainide toxicity: no difference, no sink. ( Cave, G; Harvey, M; Heys, D; Quinn, P, 2013) |
| " Both patients had rapid onset of symptoms due to the very good bioavailability of the drug." | 1.28 | Primary and secondary detoxification in severe flecainide intoxication. ( Barckow, D; Götz, D; Pohle, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cave, G | 1 |
| Harvey, M | 1 |
| Quinn, P | 1 |
| Heys, D | 1 |
| Kit, YC | 1 |
| Yin, LH | 1 |
| Leung, MK | 1 |
| Gay, KP | 1 |
| Tak, WY | 1 |
| Palmiere, C | 1 |
| Lesta, Mdel M | 1 |
| Sabatasso, S | 1 |
| Mangin, P | 1 |
| Augsburger, M | 1 |
| Sporkert, F | 1 |
| Devin, R | 1 |
| Garrett, P | 1 |
| Anstey, C | 1 |
| Maury, P | 1 |
| Vuille, C | 1 |
| Metzger, J | 1 |
| Veragut, B | 1 |
| Schoenenberger, I | 1 |
| Elamly, A | 1 |
| Chevrolet, JC | 1 |
| Corkeron, MA | 1 |
| van Heerden, PV | 1 |
| Newman, SM | 1 |
| Dusci, L | 1 |
| Buss, J | 1 |
| Nitsch, J | 1 |
| Köppel, C | 1 |
| Tenczer, J | 1 |
| Peixoto-Menezes, KM | 1 |
| Götz, D | 1 |
| Pohle, S | 1 |
| Barckow, D | 1 |
1 review available for flecainide and Poisoning
| Article | Year |
|---|---|
[Severe flecainide acetate poisoning. Apropos of a case].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate | 1999 |
9 other studies available for flecainide and Poisoning
| Article | Year |
|---|---|
Hypertonic sodium bicarbonate versus intravenous lipid emulsion in a rabbit model of intravenous flecainide toxicity: no difference, no sink.
Topics: Animals; Anti-Arrhythmia Agents; Antidotes; Blood Pressure; Disease Models, Animal; Endpoint Determi | 2013 |
CASH as a mnemonic for indications of sodium bicarbonate for sodium channel blocker intoxication.
Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Magnesium; | 2009 |
Usefulness of postmortem biochemistry in forensic pathology: illustrative case reports.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Adult; Aged; Anti-Arrhythmia Agents; Benzodiazepines; Biomarkers; | 2012 |
Managing cardiovascular collapse in severe flecainide overdose without recourse to extracorporeal therapy.
Topics: Adult; Anti-Arrhythmia Agents; Cardiovascular Diseases; Charcoal; Drug Overdose; Electrocardiography | 2007 |
Extracorporeal circulatory support in near-fatal flecainide overdose.
Topics: Adult; Anti-Arrhythmia Agents; Cardiopulmonary Bypass; Drug Overdose; Electrocardiography; Extracorp | 1999 |
[Flecainide poisoning].
Topics: Antidotes; Flecainide; Hemoperfusion; Humans; Poisoning | 1992 |
[Flecainide poisoning].
Topics: Charcoal; Flecainide; Humans; Poisoning | 1992 |
Formation of formaldehyde adducts from various drugs by use of methanol in a toxicological screening procedure with gas chromatography-mass spectrometry.
Topics: Adrenergic beta-Antagonists; Flecainide; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; | 1991 |
Primary and secondary detoxification in severe flecainide intoxication.
Topics: Adolescent; Adult; Cardiac Pacing, Artificial; Charcoal; Flecainide; Gastric Lavage; Hemoperfusion; | 1991 |