flecainide has been researched along with Myotonic Dystrophy in 2 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the mechanisms of cardiac arrhythmias in DM1 are unknown." | 1.42 | Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1. ( Algalarrondo, V; Azibi, K; Balse, E; Beldjord, C; Coulombe, A; Duboc, D; Eymard, B; Fischmeister, R; Gourdon, G; Hatem, SN; Sebag, F; Wahbi, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maury, P | 1 |
| Audoubert, M | 1 |
| Cintas, P | 1 |
| Rollin, A | 1 |
| Duparc, A | 1 |
| Mondoly, P | 1 |
| Chiriac, AM | 1 |
| Acket, B | 1 |
| Zhao, X | 1 |
| Pasquié, JL | 1 |
| Cardin, C | 1 |
| Delay, M | 1 |
| Sadron, M | 1 |
| Carrié, D | 1 |
| Galinier, M | 1 |
| Davy, JM | 1 |
| Arne-Bès, MC | 1 |
| Raczka, F | 1 |
| Algalarrondo, V | 1 |
| Wahbi, K | 1 |
| Sebag, F | 1 |
| Gourdon, G | 1 |
| Beldjord, C | 1 |
| Azibi, K | 1 |
| Balse, E | 1 |
| Coulombe, A | 1 |
| Fischmeister, R | 1 |
| Eymard, B | 1 |
| Duboc, D | 1 |
| Hatem, SN | 1 |
2 other studies available for flecainide and Myotonic Dystrophy
| Article | Year |
|---|---|
Prevalence of type 1 Brugada ECG pattern after administration of Class 1C drugs in patients with type 1 myotonic dystrophy: Myotonic dystrophy as a part of the Brugada syndrome.
Topics: Adult; Ajmaline; Brugada Syndrome; Death, Sudden, Cardiac; Defibrillators, Implantable; Electrocardi | 2014 |
Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1.
Topics: Action Potentials; Aging; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Brugada Syndrome; C | 2015 |