flecainide has been researched along with Laryngismus in 2 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
Laryngismus: A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "More recently, severe neonatal episodic laryngospasm (SNEL) has been described in a small number of patients." | 2.53 | Flecainide-Responsive Myotonia Permanens With SNEL Onset: A New Case and Literature Review. ( Musumeci, O; Portaro, S; Rodolico, C; Sinicropi, S; Toscano, A; Valenzise, M, 2016) |
| "Residue G1306 Neonatal laryngospasm and unusual distribution of myotonia, muscle hypertrophy, and weakness encourage direct search for the G1306E mutation, a hotspot for de-novo mutations." | 1.46 | Myotonia permanens with Nav1.4-G1306E displays varied phenotypes during course of life. ( Bertini, E; D'Amico, A; Jurkat-Rott, K; Lehmann-Horn, F; Lomonaco, M; Merlini, L; Nelson, KR; Philippi, H; Siciliano, G; Spaans, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lehmann-Horn, F | 1 |
| D'Amico, A | 1 |
| Bertini, E | 1 |
| Lomonaco, M | 1 |
| Merlini, L | 1 |
| Nelson, KR | 1 |
| Philippi, H | 1 |
| Siciliano, G | 1 |
| Spaans, F | 1 |
| Jurkat-Rott, K | 1 |
| Portaro, S | 1 |
| Rodolico, C | 1 |
| Sinicropi, S | 1 |
| Musumeci, O | 1 |
| Valenzise, M | 1 |
| Toscano, A | 1 |
1 review available for flecainide and Laryngismus
| Article | Year |
|---|---|
Flecainide-Responsive Myotonia Permanens With SNEL Onset: A New Case and Literature Review.
Topics: Child; Female; Flecainide; Humans; Hypertrophy; Laryngismus; Muscle, Skeletal; Mutation; Myotonia Co | 2016 |
1 other study available for flecainide and Laryngismus
| Article | Year |
|---|---|
Myotonia permanens with Nav1.4-G1306E displays varied phenotypes during course of life.
Topics: Action Potentials; Adolescent; Adult; Age Factors; Child; Child, Preschool; Dyspnea; Exercise; Femal | 2017 |