flecainide has been researched along with Edema, Fetal in 31 studies
Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).
| Excerpt | Relevance | Reference |
|---|---|---|
| "An infant with intrauterine supraventricular tachycardia and fetal hydrops, successfully treated with administration of flecainide acetate to the mother had conjugated hyperbilirubinemia shortly after birth." | 7.69 | Conjugated hyperbilirubinemia in a newborn infant after maternal (transplacental) treatment with flecainide acetate for fetal tachycardia and fetal hydrops. ( Carlson, DE; Cocjin, J; Rosenthal, P; Santulli, TV; Vanderhal, AL, 1995) |
| " In the case of atrial flutters the pregnant woman is treated with sotalol administered orally and, if no sinus rhythm is obtained nor a reduced ventricular rhythm occurs, subsequently with digoxin." | 4.81 | [Protocols for the treatment of supraventricular tachycardias in the fetus]. ( Ambachtsheer, EB; Meijboom, EJ; Oudijk, MA; Stoutenbeek, P, 2001) |
| "High-dose flecainide and digoxin combination offers effective treatment strategy in fetuses with hydrops and tachyarrhythmia with favourable outcomes." | 4.12 | Favourable outcome for hydrops or cardiac failure associated with fetal tachyarrhythmia: a 20-year review. ( Beattie, RB; Tunca Sahin, G; Uzun, O, 2022) |
| "We describe two cases of fetal atrial flutter associated with severe fetal hydrops which were unresponsive to digoxin but were successfully treated with flecainide acetate." | 3.70 | Two cases of atrial flutter with fetal hydrops: successful fetal drug therapy. ( Kim, A; Ko, JK; Lee, IS; Lee, PR; Mok, JE; Won, HS; Yoo, HK; Yoo, SJ, 1998) |
| "We discovered supraventricular tachycardia with advanced hydrops in the setting of normal cardiac anatomy at 26 weeks of gestation which resolved successfully following administration of digoxin and flecainide to the mother." | 3.70 | Fetal hydrops due to a tachyarrhythmia progressing to organic pulmonary stenosis. ( Fesslova, V; Nicolini, U; Villa, L, 2000) |
| "An infant with intrauterine supraventricular tachycardia and fetal hydrops, successfully treated with administration of flecainide acetate to the mother had conjugated hyperbilirubinemia shortly after birth." | 3.69 | Conjugated hyperbilirubinemia in a newborn infant after maternal (transplacental) treatment with flecainide acetate for fetal tachycardia and fetal hydrops. ( Carlson, DE; Cocjin, J; Rosenthal, P; Santulli, TV; Vanderhal, AL, 1995) |
| "We report a case of fetal supraventricular tachycardia with intra uterine cardiac failure, treated with oral administration of flecainide acetate (Flecaine) to the mother." | 3.69 | [Flecaine: drug of choice for supraventricular tachycardias with anasarca. A case report]. ( Barjot, P; Febbraro, W; Hamel, P; Iselin, M; Lindet, Y; Muller, G, 1997) |
| "Fetal supraventricular tachycardia is a relatively uncommon cardiac rhythm abnormality which is often associated with adverse perinatal outcomes if untreated." | 1.62 | Management of Fetal Supraventricular Tachycardia: Case Series from a Tertiary Perinatal Cardiac Center. ( Broom, E; Gardener, G; Gooi, A; Kostner, K; Kumar, S; Lee-Tannock, A; Petersen, S; Thomas, JT; Ward, C, 2021) |
| "Supraventricular tachycardia is the most common fetal tachyarrhythmia and if persistent often associated with fetal hydrops which can cause intrauterine and neonatal death." | 1.56 | Refractory Fetal Supraventricular Tachycardia with Hydrops Successfully Converted by Intraperitoneal Flecainide in the Fetus: A Case Report. ( Ekelund, CK; Gembruch, U; Harmsen, L; Jaeggi, E; Jensen, LN; Nørgaard, LN; Petersen, OB; Sundberg, K; Vedel, C; Vejlstrup, N, 2020) |
| "Flecainide was discontinued at 31 weeks' gestation due to elevated liver enzymes." | 1.56 | Complete resolution of arrhythmia-induced hydrops fetalis in utero. ( Alapati, S; Dhuka, S; Kauffman, RP; Narayanan, M, 2020) |
| "Fetal tachyarrhythmia can lead to fetal hydrops due to heart failure." | 1.43 | High-dose flecainide is the most effective treatment of fetal supraventricular tachycardia. ( Berg, C; Geipel, A; Gembruch, U; Gottschalk, I; Herberg, U; Strizek, B, 2016) |
| "Treatment with digoxin and flecainide was successful; the heart rate returned to sinus rhythm within one day, and fetal hydrops resolved within 8 days of treatment." | 1.32 | Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report. ( Anteby, EY; Hamani, Y; Porat, S; Yagel, S, 2003) |
| "Tachycardia was observed in 15% of cases (three cases of supraventricular tachycardia [SVT] and two cases of auricular flutter [AF])." | 1.31 | [Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases]. ( Dubos, JP; Dufour, P; Puech, F; Subtil, D; Vaast, P; Vaksmann, G; Valat, AS; Vautier-Rit, S, 2000) |
| "Most arrhythmias associated with fetal hydrops can be controlled with transplacental treatment, but the mortality in this group is 27%." | 1.30 | Fetal tachycardias: management and outcome of 127 consecutive cases. ( Sharland, GK; Simpson, JM, 1998) |
| "Three patients with fetal hydrops died." | 1.29 | Management outcome and follow-up of fetal tachycardia. ( Brenner, JI; Copel, JA; Kleinman, CS; Meijboom, EJ; Stoutenbeek, P; van Engelen, AD; Weijtens, O, 1994) |
| "The fetus required no further treatment in pregnancy or at follow up." | 1.28 | Intermittent fetal tachycardia and fetal hydrops. ( James, DK; Martin, R; Smoleniec, JS, 1991) |
| "In cases of non-immune hydrops fetalis caused by tachyarrhythmias, the transplacental passage of antiarrhythmic drugs may be hampered." | 1.27 | Direct intrauterine fetal treatment of fetal tachyarrhythmia with severe hydrops fetalis by antiarrhythmic drugs. ( Bald, R; Gembruch, U; Hansmann, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 10 (32.26) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 5 (16.13) | 2.80 |
| Authors | Studies |
|---|---|
| Tunca Sahin, G | 1 |
| Beattie, RB | 1 |
| Uzun, O | 2 |
| Broom, E | 1 |
| Thomas, JT | 1 |
| Petersen, S | 1 |
| Gooi, A | 1 |
| Ward, C | 1 |
| Gardener, G | 1 |
| Kostner, K | 1 |
| Lee-Tannock, A | 1 |
| Kumar, S | 1 |
| Refaat, M | 1 |
| El Dick, J | 1 |
| Sabra, M | 1 |
| Bitar, F | 1 |
| Tayeh, C | 1 |
| Abutaqa, M | 1 |
| Arabi, M | 1 |
| Vedel, C | 1 |
| Vejlstrup, N | 1 |
| Jensen, LN | 1 |
| Ekelund, CK | 1 |
| Nørgaard, LN | 1 |
| Harmsen, L | 1 |
| Petersen, OB | 1 |
| Jaeggi, E | 1 |
| Gembruch, U | 4 |
| Sundberg, K | 1 |
| Narayanan, M | 1 |
| Dhuka, S | 1 |
| Alapati, S | 1 |
| Kauffman, RP | 1 |
| Gesuete, V | 1 |
| Fantasia, I | 1 |
| Lo Bello, L | 1 |
| Rizzante, E | 1 |
| D'Agata Mottolese, B | 1 |
| Stampalija, T | 1 |
| Strizek, B | 1 |
| Berg, C | 1 |
| Gottschalk, I | 1 |
| Herberg, U | 1 |
| Geipel, A | 2 |
| Ekiz, A | 1 |
| Kaya, B | 1 |
| Bornaun, H | 1 |
| Acar, DK | 1 |
| Avci, ME | 1 |
| Bestel, A | 1 |
| Yildirim, G | 1 |
| Babaoglu, K | 1 |
| Sinha, A | 1 |
| Massias, S | 1 |
| Beattie, B | 1 |
| Jouannic, JM | 2 |
| Delahaye, S | 2 |
| Fermont, L | 2 |
| Le Bidois, J | 2 |
| Villain, E | 2 |
| Dumez, Y | 2 |
| Dommergues, M | 2 |
| Porat, S | 1 |
| Anteby, EY | 1 |
| Hamani, Y | 1 |
| Yagel, S | 1 |
| Gerli, S | 1 |
| Clerici, G | 1 |
| Mattei, A | 1 |
| Di Renzo, GC | 1 |
| Kohl, T | 1 |
| Tercanli, S | 1 |
| Kececioglu, D | 1 |
| Holzgreve, W | 1 |
| Vanderhal, AL | 1 |
| Cocjin, J | 1 |
| Santulli, TV | 1 |
| Carlson, DE | 1 |
| Rosenthal, P | 1 |
| van Engelen, AD | 1 |
| Weijtens, O | 1 |
| Brenner, JI | 1 |
| Kleinman, CS | 1 |
| Copel, JA | 1 |
| Stoutenbeek, P | 2 |
| Meijboom, EJ | 2 |
| Hamel, P | 3 |
| Febbraro, W | 2 |
| Barjot, P | 3 |
| Lindet, Y | 2 |
| Muller, G | 2 |
| Iselin, M | 2 |
| Azancot-Benisty, A | 1 |
| Areias, JC | 1 |
| Oberhänsli, I | 1 |
| Schmidt, KG | 1 |
| Tulzer, G | 1 |
| Viart, P | 1 |
| Calmelet, P | 1 |
| Maragnes, P | 1 |
| Herlicoviez, M | 1 |
| Won, HS | 1 |
| Lee, IS | 1 |
| Yoo, HK | 1 |
| Yoo, SJ | 1 |
| Ko, JK | 1 |
| Lee, PR | 1 |
| Kim, A | 1 |
| Mok, JE | 1 |
| Simpson, JM | 1 |
| Sharland, GK | 1 |
| Edwards, A | 1 |
| Peek, MJ | 1 |
| Curren, J | 1 |
| Midgley, DY | 1 |
| Harding, K | 1 |
| Fesslova, V | 1 |
| Villa, L | 1 |
| Nicolini, U | 1 |
| Vautier-Rit, S | 1 |
| Dufour, P | 1 |
| Vaksmann, G | 1 |
| Subtil, D | 1 |
| Vaast, P | 1 |
| Valat, AS | 1 |
| Dubos, JP | 1 |
| Puech, F | 1 |
| Oudijk, MA | 1 |
| Ambachtsheer, EB | 1 |
| Abraham, P | 1 |
| Krapp, M | 1 |
| Baschat, AA | 1 |
| Germer, U | 1 |
| Smoleniec, JS | 1 |
| Martin, R | 1 |
| James, DK | 1 |
| Hansmann, M | 1 |
| Bald, R | 1 |
3 reviews available for flecainide and Edema, Fetal
| Article | Year |
|---|---|
Sotalol as an effective adjunct therapy in the management of supraventricular tachycardia induced fetal hydrops fetalis.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Female; Fetal Diseases; Flecainid | 2020 |
Is antiarrhythmic therapy safe in twin pregnancies?
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Preg | 2019 |
[Protocols for the treatment of supraventricular tachycardias in the fetus].
Topics: Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Drug Therapy, Combination; Fema | 2001 |
28 other studies available for flecainide and Edema, Fetal
| Article | Year |
|---|---|
Favourable outcome for hydrops or cardiac failure associated with fetal tachyarrhythmia: a 20-year review.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cesarean Section; Digoxin; Female; Fetal Diseases; Fle | 2022 |
Management of Fetal Supraventricular Tachycardia: Case Series from a Tertiary Perinatal Cardiac Center.
Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Retr | 2021 |
Refractory Fetal Supraventricular Tachycardia with Hydrops Successfully Converted by Intraperitoneal Flecainide in the Fetus: A Case Report.
Topics: Adult; Anti-Arrhythmia Agents; Female; Fetal Therapies; Flecainide; Humans; Hydrops Fetalis; Pregnan | 2020 |
Complete resolution of arrhythmia-induced hydrops fetalis in utero.
Topics: Anti-Arrhythmia Agents; Cesarean Section; Digoxin; Echocardiography; Female; Fetal Therapies; Flecai | 2020 |
High-dose flecainide is the most effective treatment of fetal supraventricular tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Heart Rate, Fetal; Humans; Hydrops Fetal | 2016 |
Flecainide as first-line treatment for fetal supraventricular tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Echocardiography; Female; Fetal Diseases; Fetal Heart; Flecainide; Ge | 2018 |
Rapid control of foetal supraventricular tachycardia with digoxin and flecainide combination treatment.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Drug Therapy, Combination; Echoc | 2012 |
Fetal supraventricular tachycardia: a role for amiodarone as second-line therapy?
Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Flecainide; Hydrops Fetalis; | 2003 |
Fetal supraventricular tachycardia diagnosed and treated at 13 weeks of gestation: a case report.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Female; Flecainide; Gestational Age; Humans; Hydrops Fetalis | 2003 |
[Results of prenatal management of fetuses with supraventricular tachycardia. A series of 66 cases].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Clinical Protocols; Digoxin; Echocardiography; F | 2003 |
Flecainide treatment of fetal tachycardia and hydrops fetalis in a twin pregnancy.
Topics: Anti-Arrhythmia Agents; Echocardiography; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetali | 2006 |
Direct fetal administration of adenosine for the termination of incessant supraventricular tachycardia.
Topics: Adenosine; Digoxin; Female; Fetal Death; Flecainide; Gestational Age; Heart Rate; Humans; Hydrops Fe | 1995 |
Conjugated hyperbilirubinemia in a newborn infant after maternal (transplacental) treatment with flecainide acetate for fetal tachycardia and fetal hydrops.
Topics: Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Infant; Infant, Newborn; Jaundice, Neon | 1995 |
Management outcome and follow-up of fetal tachycardia.
Topics: Atrial Flutter; Digoxin; Echocardiography; Female; Fetal Diseases; Fetal Heart; Flecainide; Follow-U | 1994 |
[Flecaine: drug of choice for supraventricular tachycardias with anasarca. A case report].
Topics: Anti-Arrhythmia Agents; Electrocardiography; Female; Fetal Diseases; Flecainide; Heart Failure; Huma | 1997 |
[Fetal supraventricular tachycardia with anasarca complicating benign extrasystole: treatment with flecainide. Apropos of a case].
Topics: Anti-Arrhythmia Agents; Atrial Premature Complexes; Dose-Response Relationship, Drug; Drug Administr | 1997 |
[European protocol for the management of fetal supraventricular tachycardia. European Association of Pediatric Cardiology].
Topics: Anti-Arrhythmia Agents; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Fetal Death | 1997 |
Flecainide against fetal supraventricular tachycardia complicated by hydrops fetalis.
Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Follow-Up Studies; Humans; Hydrops Fetal | 1998 |
Two cases of atrial flutter with fetal hydrops: successful fetal drug therapy.
Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Female; Flecainide; Humans; Hydrops Fetalis; | 1998 |
Fetal tachycardias: management and outcome of 127 consecutive cases.
Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Chi-Square Distribution; Digoxin; Female; Fetal Distr | 1998 |
Transplacental flecainide therapy for fetal supraventricular tachycardia in a twin pregnancy.
Topics: Adult; Anti-Arrhythmia Agents; Diseases in Twins; Ethics, Medical; Female; Fetal Diseases; Flecainid | 1999 |
The Mirror syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Pre-Ecla | 2000 |
Fetal hydrops due to a tachyarrhythmia progressing to organic pulmonary stenosis.
Topics: Adult; Anti-Arrhythmia Agents; Digoxin; Echocardiography, Doppler; Female; Flecainide; Humans; Hydro | 2000 |
[Fetal arrhythmias: diagnosis, prognosis, treatment; apropos of 33 cases].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Echocardiog | 2000 |
Supraventricular tachycardia with hydrops in a 27-week premature baby.
Topics: Anti-Arrhythmia Agents; Bradycardia; Electrocardiography; Flecainide; Humans; Hydrops Fetalis; Infan | 2001 |
Flecainide in the intrauterine treatment of fetal supraventricular tachycardia.
Topics: Anti-Arrhythmia Agents; Cardiotocography; Digoxin; Female; Fetal Diseases; Flecainide; Humans; Hydro | 2002 |
Intermittent fetal tachycardia and fetal hydrops.
Topics: Adult; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Pregnancy; Tachycardia, Supraven | 1991 |
Direct intrauterine fetal treatment of fetal tachyarrhythmia with severe hydrops fetalis by antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Medigoxin; Preg | 1988 |