Page last updated: 2024-10-27

flecainide and Drop Attack

flecainide has been researched along with Drop Attack in 21 studies

Flecainide: A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial ARRHYTHMIAS and TACHYCARDIAS.
flecainide : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2,5-bis(2,2,2-trifluoroethoxy)benzoic acid with the primary amino group of piperidin-2-ylmethylamine. An antiarrhythmic agent used (in the form of its acetate salt) to prevent and treat tachyarrhythmia (abnormal fast rhythm of the heart).

Research Excerpts

ExcerptRelevanceReference
"This study sought to compare the differences between procainamide and flecainide to stress the His-Purkinje system during electrophysiological study (EPS) in patients with syncope and bundle branch block (BBB)."7.91Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration. ( Ferreira-Gonzalez, I; Francisco-Pasqual, J; García-Dorado, D; Martin-Sanchez, G; Moya-Mitjans, A; Oristrell, G; Perez-Rodon, J; Rivas-Gandara, N; Roca-Luque, I; Rodríguez-García, J; Santos-Ortega, A, 2019)
"In patients with false-negative responses to the provocative testing with flecainide, cardiac syncope predicts SCA, allowing a more extensive and individualized evaluation."7.88Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing. ( Avanzas, P; Calvo, D; Coto, E; García, D; Gómez, J; González-Vasserot, M; María de la Hera, J; Morís, C; Pablo Flórez, J; Pérez, D; Reguero, J; Rubín, J; Valverde, I, 2018)
"The flecainide test is widely used in Brugada syndrome."7.72Flecainide test in Brugada syndrome: a reproducible but risky tool. ( Ceriotti, C; Galimberti, P; Gasparini, M; Mantica, M; Napolitano, C; Priori, SG; Simonini, S, 2003)
" We describe the case of a 62-year-old male with latent Brugada syndrome in whom the intravenous infusion of flecainide for paroxysmal atrial fibrillation caused ECG abnormalities similar to those of an acute septal myocardial infarction."7.72[Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct]. ( Carotenuto, F; Cirillo, R; D'Errico, L; di Palma, F; Fontana, D; Granato, L; Pagano, V; Sestri, C; Vitiello, N, 2003)
" This study assessed in 1,330 patients followed up for 292 +/- 393 days the predictive value for cardiovascular safety of a system by which patients were classified according to ventricular arrhythmias on entry, presence or absence of organic heart disease and drug dose for flecainide acetate."7.67Classification by type of ventricular arrhythmia predicts frequency of adverse cardiac events from flecainide. ( Anderson, JL; Gentzkow, GD; Morganroth, J, 1986)
"This study sought to compare the differences between procainamide and flecainide to stress the His-Purkinje system during electrophysiological study (EPS) in patients with syncope and bundle branch block (BBB)."3.91Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration. ( Ferreira-Gonzalez, I; Francisco-Pasqual, J; García-Dorado, D; Martin-Sanchez, G; Moya-Mitjans, A; Oristrell, G; Perez-Rodon, J; Rivas-Gandara, N; Roca-Luque, I; Rodríguez-García, J; Santos-Ortega, A, 2019)
"In patients with false-negative responses to the provocative testing with flecainide, cardiac syncope predicts SCA, allowing a more extensive and individualized evaluation."3.88Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing. ( Avanzas, P; Calvo, D; Coto, E; García, D; Gómez, J; González-Vasserot, M; María de la Hera, J; Morís, C; Pablo Flórez, J; Pérez, D; Reguero, J; Rubín, J; Valverde, I, 2018)
"The flecainide test is widely used in Brugada syndrome."3.72Flecainide test in Brugada syndrome: a reproducible but risky tool. ( Ceriotti, C; Galimberti, P; Gasparini, M; Mantica, M; Napolitano, C; Priori, SG; Simonini, S, 2003)
" We describe the case of a 62-year-old male with latent Brugada syndrome in whom the intravenous infusion of flecainide for paroxysmal atrial fibrillation caused ECG abnormalities similar to those of an acute septal myocardial infarction."3.72[Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct]. ( Carotenuto, F; Cirillo, R; D'Errico, L; di Palma, F; Fontana, D; Granato, L; Pagano, V; Sestri, C; Vitiello, N, 2003)
" This study assessed in 1,330 patients followed up for 292 +/- 393 days the predictive value for cardiovascular safety of a system by which patients were classified according to ventricular arrhythmias on entry, presence or absence of organic heart disease and drug dose for flecainide acetate."3.67Classification by type of ventricular arrhythmia predicts frequency of adverse cardiac events from flecainide. ( Anderson, JL; Gentzkow, GD; Morganroth, J, 1986)
"This multicenter study suggests that oral flecainide therapy is an effective and safe means of suppressing VAs in patients with ATS with KCNJ2 mutations, though the U-wave amplitude remained unchanged by flecainide."2.80Efficacy and safety of flecainide for ventricular arrhythmias in patients with Andersen-Tawil syndrome with KCNJ2 mutations. ( Aiba, T; Anzai, T; Hayashi, H; Horie, M; Ishibashi, K; Ishihara, M; Kamakura, S; Kimura, H; Kusano, K; Miyamoto, K; Miyamoto, Y; Nakajima, I; Noda, T; Ogawa, H; Ohno, S; Okamura, H; Shimizu, W; Tanioka, Y; Tsuboi, I; Tsuchiya, T; Yasuda, S; Yasuoka, C; Yoshida, Y, 2015)
"The short QT syndrome is characterized by familial sudden death, short refractory periods, and inducible ventricular fibrillation."2.71Short QT Syndrome: a familial cause of sudden death. ( Bianchi, F; Borggrefe, M; Gaita, F; Giustetto, C; Grossi, S; Riccardi, R; Richiardi, E; Schimpf, R; Wolpert, C, 2003)
"Catecholaminergic polymorphic ventricular tachycardia was diagnosed with the aid of an implantable loop recorder."1.39A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia. ( Anastasakis, A; Kotsaka, X; Luria, D; Mantziari, L; Paraskevaidis, S; Styliadis, IH; Vassilikos, V, 2013)
"Syncope was abolished after successful radiofrequency catheter ablation of the AFL."1.31Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs. ( Azegami, K; Hiejima, K; Hirao, K; Horikawa, T; Kawabata, M; Motokawa, K; Suzuki, F; Suzuki, K, 2001)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's2 (9.52)18.2507
2000's7 (33.33)29.6817
2010's7 (33.33)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Cheung, CC1
Scheinman, M1
Lee, BK1
Luna-López, R1
Datino, T1
Espinosa, MÁ1
Fernández-Avilés, F1
Arenal, Á1
Pablo Flórez, J1
García, D1
Valverde, I1
Rubín, J1
Pérez, D1
González-Vasserot, M1
Reguero, J1
María de la Hera, J1
Avanzas, P1
Gómez, J1
Coto, E1
Morís, C1
Calvo, D1
El-Battrawy, I1
Borggrefe, M2
Lang, S1
Zhou, X1
Akin, I1
Roca-Luque, I1
Francisco-Pasqual, J1
Oristrell, G1
Rodríguez-García, J1
Santos-Ortega, A1
Martin-Sanchez, G1
Rivas-Gandara, N1
Perez-Rodon, J1
Ferreira-Gonzalez, I1
García-Dorado, D1
Moya-Mitjans, A1
Lokhandwala, Y1
Kumar, B1
Sato, A1
Takano, T1
Chinushi, M1
Minamino, T1
Mantziari, L1
Vassilikos, V1
Anastasakis, A1
Kotsaka, X1
Paraskevaidis, S1
Styliadis, IH1
Luria, D1
Miyamoto, K1
Aiba, T1
Kimura, H1
Hayashi, H2
Ohno, S1
Yasuoka, C1
Tanioka, Y1
Tsuchiya, T1
Yoshida, Y1
Tsuboi, I1
Nakajima, I1
Ishibashi, K1
Okamura, H1
Noda, T1
Ishihara, M1
Anzai, T1
Yasuda, S1
Miyamoto, Y1
Kamakura, S1
Kusano, K1
Ogawa, H1
Horie, M1
Shimizu, W1
Beinart, R1
Michailidis, A1
Gurevitz, OT1
Glikson, M1
Gasparini, M1
Priori, SG1
Mantica, M1
Napolitano, C1
Galimberti, P1
Ceriotti, C1
Simonini, S1
Vitiello, N1
Cirillo, R1
Fontana, D1
Granato, L1
Sestri, C1
Pagano, V1
D'Errico, L1
Carotenuto, F1
di Palma, F1
Gaita, F1
Giustetto, C1
Bianchi, F1
Wolpert, C1
Schimpf, R1
Riccardi, R1
Grossi, S1
Richiardi, E1
Haghjoo, M1
Arya, A1
Emkanjoo, Z1
Sadr-Ameli, MA1
Füessl, HS1
Greenberg, HM1
Dwyer, EM1
Hochman, JS1
Steinberg, JS1
Echt, DS1
Peters, RW1
Itoh, E1
Suzuki, K2
Tanabe, Y1
Kawabata, M1
Hirao, K1
Horikawa, T1
Motokawa, K1
Suzuki, F1
Azegami, K1
Hiejima, K1
Borgeat, A1
Grbic, M1
Morganroth, J1
Anderson, JL1
Gentzkow, GD1
Wehr, M1
Noll, B1
Krappe, J1

Trials

3 trials available for flecainide and Drop Attack

ArticleYear
Efficacy and safety of flecainide for ventricular arrhythmias in patients with Andersen-Tawil syndrome with KCNJ2 mutations.
    Heart rhythm, 2015, Volume: 12, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Andersen Syndrome; Anti-Arrhythmia Agents; Electrocardiogra

2015
Short QT Syndrome: a familial cause of sudden death.
    Circulation, 2003, Aug-26, Volume: 108, Issue:8

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Complexes, Premature; Ch

2003
Interaction of ischaemia and encainide/flecainide treatment: a proposed mechanism for the increased mortality in CAST I.
    British heart journal, 1995, Volume: 74, Issue:6

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Databases, Factual; Death, Sudden, Cardiac; Drug Interactio

1995

Other Studies

18 other studies available for flecainide and Drop Attack

ArticleYear
A peculiar case of palpitations and syncope.
    Heart rhythm, 2022, Volume: 19, Issue:3

    Topics: Andersen Syndrome; Arrhythmias, Cardiac; Flecainide; Humans; Mutation; Syncope

2022
Permanent atrioventricular block after flecainide testing.
    Revista espanola de cardiologia (English ed.), 2020, Volume: 73, Issue:2

    Topics: Aged; Atrioventricular Block; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Pac

2020
Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018, 06-01, Volume: 20, Issue:FI1

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; False Negative Reactions; Fema

2018
Sodium channel blockers in Brugada syndrome.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2018, 06-01, Volume: 20, Issue:FI1

    Topics: Ajmaline; Brugada Syndrome; Flecainide; Humans; Sodium Channel Blockers; Syncope

2018
Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration.
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Bundle-Branch Block; Electrocardiography; Electrophysiologic Techniques, Ca

2019
Flecainide to Unmask Infranodal Disease: A Better Sieve?
    JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2

    Topics: Bundle-Branch Block; Flecainide; Humans; Procainamide; Syncope

2019
Usefulness of the intravenous flecainide challenge test before oral flecainide treatment in a patient with Andersen-Tawil syndrome.
    BMJ case reports, 2019, Jul-15, Volume: 12, Issue:7

    Topics: Administration, Intravenous; Administration, Oral; Adult; Andersen Syndrome; Anti-Arrhythmia Agents;

2019
A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2013, Volume: 18, Issue:6

    Topics: Adolescent; Anti-Arrhythmia Agents; Defibrillators, Implantable; Female; Flecainide; Follow-Up Studi

2013
Is flecainide dangerous in long QT-3 patients?
    Pacing and clinical electrophysiology : PACE, 2009, Volume: 32, Issue:1

    Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Long QT S

2009
Flecainide test in Brugada syndrome: a reproducible but risky tool.
    Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:1P2

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Death, Sudden, Cardiac; Electrocardi

2003
[Infusion of flecainide in a patient with atrial fibrillation and latent Brugada's syndrome has determined modifications of the electrocardiogram similar to those of a septal myocardial infarct].
    Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2003, Volume: 4, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Death, Sudden, Cardiac; Echocardiography; Electrocardio

2003
Clinical and electrophysiologic profile of Brugada syndrome in Iranian patients.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Bundle-Branch Block; Defibrillators, Implantable; Electric Stimulatio

2005
[Reason for worry: syncope in the morning].
    MMW Fortschritte der Medizin, 2005, Apr-21, Volume: 147, Issue:16

    Topics: Anti-Arrhythmia Agents; Circadian Rhythm; Death, Sudden, Cardiac; Diagnosis, Differential; Electroca

2005
A case of vasospastic angina presenting Brugada-type ECG abnormalities.
    Japanese circulation journal, 1999, Volume: 63, Issue:6

    Topics: Acetylcholine; Aged; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiovascular Agents; Chest

1999
Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs.
    Journal of electrocardiology, 2001, Volume: 34, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Catheter Ablation; Electrocardiography; Electrophysio

2001
[Syncope in a 16-year-old young man during a football match].
    Schweizerische medizinische Wochenschrift, 1986, Oct-11, Volume: 116, Issue:41

    Topics: Adolescent; Atrial Fibrillation; Flecainide; Humans; Male; Syncope; Wolff-Parkinson-White Syndrome

1986
Classification by type of ventricular arrhythmia predicts frequency of adverse cardiac events from flecainide.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:3

    Topics: Arrhythmias, Cardiac; Death, Sudden; Drug Administration Schedule; Flecainide; Heart Failure; Humans

1986
Flecainide-induced aggravation of ventricular arrhythmias.
    The American journal of cardiology, 1985, Jun-01, Volume: 55, Issue:13 Pt 1

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Female; Flecainide; Humans

1985